iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011011

Ensembl Protein ID

ENSAMXP00000016898.1

UniProt Accession

W5LAN6; W5LAN6_ASTMX

Genbank Protein ID

ENSAMXP00000016898

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01078653

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000016403.1	ENSAMXT00000016898.1	ENSAMXP00000016898.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	2.10e-148	493.8	177	483
E3 adaptor/Cullin RING/DCX/DWD	1.90e-25	88.1	313	343

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+++avGt+kg v+i+D+++ kk
   Q: 177  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNHVAVGTHKGFVQIWDAAAGKK 265
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           ++ l+gh+arvgaL+Wna++lssGsrd++il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss +P+++++
   Q: 266  LFALEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSVQPVQQYT 354
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntlt++ l++idtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl+++a+l+g
   Q: 355  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTAQPLQCIDTGSQVCNLAWSKHTNELVSTHGYSQNQILVWKYPSLTQIAKLTG 443
           ***************************************************************************************** PP
   S: 266  heaRvlsl..alspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+l  a+spdgeaivt+agDetlrfw++f+k++++
   Q: 444  HSYRVLYLiqAMSPDGEAIVTGAGDETLRFWNVFSKTRST 483
           *****986448************************99875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 313  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 343
           8**********98889**************9 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MDQDYERRLL RQINVQNDNA SPVKVTDVIR HLTPTKSPMS SPSKHGDRFI PSRAGANWSI 60
NFHRINENEK SPSQNKKTKD ATSDTGKVDG LAYSALLKNE LLGAGIEKVQ DPQTEDRRLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTAACGGT CGTGTCCCCG TTGTCAGGTC GACAGCGACT TCCGCTGTTT TGTTTCAAAC 60
GCTGGTGACG TCCGGCCCGA AGCGCTCGTG GCCCACAGTG CATTGCGGCA GCGTCGGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002003	Ailuropoda melanoleuca	89.00	0.00e+00	894.00
IUUC-Apl-003212	Anas platyrhynchos	93.36	0.00e+00	953.00
IUUC-Aly-005442	Arabidopsis lyrata	55.93	1.00e-141	496.00
IUUC-Ath-006938	Arabidopsis thaliana	58.41	1.00e-139	489.00
IUUC-Afu-008829	Aspergillus fumigatus	49.41	2.00e-133	469.00
IUUC-Ani-009471	Aspergillus nidulans	49.49	2.00e-132	466.00
IUUC-Ate-010534	Aspergillus terreus	49.30	4.00e-132	464.00
IUUC-Bta-012586	Bos taurus	92.35	0.00e+00	944.00
IUUC-Bdi-014981	Brachypodium distachyon	71.01	8.00e-130	457.00
IUUC-Bol-016301	Brassica oleracea	56.58	8.00e-141	493.00
IUUC-Bra-017453	Brassica rapa	56.58	7.00e-141	493.00
IUUC-Cja-019929	Callithrix jacchus	92.20	0.00e+00	943.00
IUUC-Cfa-020977	Canis familiaris	92.00	0.00e+00	938.00
IUUC-Cpo-021537	Cavia porcellus	92.56	0.00e+00	945.00
IUUC-Csa-023389	Chlorocebus sabaeus	92.56	0.00e+00	947.00
IUUC-Csv-025921	Ciona savignyi	66.03	0.00e+00	668.00
IUUC-Dre-027470	Danio rerio	94.18	0.00e+00	910.00
IUUC-Dno-029629	Dasypus novemcinctus	83.85	0.00e+00	767.00
IUUC-Dor-030187	Dipodomys ordii	82.20	0.00e+00	817.00
IUUC-Dse-031502	Dothistroma septosporum	50.31	2.00e-128	452.00
IUUC-Dme-031858	Drosophila melanogaster	70.16	0.00e+00	682.00
IUUC-Ete-032562	Echinops telfairi	81.29	0.00e+00	804.00
IUUC-Eca-034210	Equus caballus	92.76	0.00e+00	947.00
IUUC-Fca-035839	Felis catus	88.33	0.00e+00	884.00
IUUC-Fal-036895	Ficedula albicollis	93.56	0.00e+00	956.00
IUUC-Gga-041025	Gallus gallus	93.16	0.00e+00	951.00
IUUC-Gac-041596	Gasterosteus aculeatus	90.96	0.00e+00	887.00
IUUC-Gma-042657	Glycine max	54.78	7.00e-137	480.00
IUUC-Ggo-045599	Gorilla gorilla	92.20	0.00e+00	907.00
IUUC-Hsa-046695	Homo sapiens	92.00	0.00e+00	942.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	91.75	0.00e+00	941.00
IUUC-Kpa-049239	Komagataella pastoris	46.02	1.00e-123	437.00
IUUC-Lch-049827	Latimeria chalumnae	92.76	0.00e+00	914.00
IUUC-Loc-052856	Lepisosteus oculatus	94.57	0.00e+00	940.00
IUUC-Laf-054321	Loxodonta africana	59.41	7.00e-147	513.00
IUUC-Mcc-055601	Macaca mulatta	92.56	0.00e+00	947.00
IUUC-Mtr-057689	Medicago truncatula	56.96	2.00e-138	485.00
IUUC-Mga-060097	Meleagris gallopavo	87.23	0.00e+00	879.00
IUUC-Mmr-061151	Microcebus murinus	83.40	0.00e+00	813.00
IUUC-Mdo-063062	Monodelphis domestica	92.96	0.00e+00	951.00
IUUC-Mmu-063731	Mus musculus	92.15	0.00e+00	941.00
IUUC-Mac-065208	Musa acuminata	58.09	5.00e-130	457.00
IUUC-Mpu-066173	Mustela putorius furo	92.56	0.00e+00	944.00
IUUC-Mlu-068030	Myotis lucifugus	92.20	0.00e+00	942.00
IUUC-Nle-070163	Nomascus leucogenys	92.56	0.00e+00	947.00
IUUC-Opr-070974	Ochotona princeps	90.41	1.00e-153	535.00
IUUC-Ont-072272	Oreochromis niloticus	90.44	0.00e+00	884.00
IUUC-Oan-073634	Ornithorhynchus anatinus	96.93	4.00e-171	593.00
IUUC-Obr-076123	Oryza brachyantha	57.32	8.00e-127	447.00
IUUC-Ogl-077294	Oryza glaberrima	52.98	4.00e-127	448.00
IUUC-Oin-080172	Oryza indica	70.03	5.00e-126	444.00
IUUC-Olo-081068	Oryza longistaminata	70.03	5.00e-126	444.00
IUUC-Ome-081250	Oryza meridionalis	53.54	1.00e-127	450.00
IUUC-Oni-083048	Oryza nivara	52.98	4.00e-127	448.00
IUUC-Opu-083333	Oryza punctata	53.32	3.00e-127	448.00
IUUC-Oru-085001	Oryza rufipogon	52.98	4.00e-127	448.00
IUUC-Osa-086243	Oryza sativa	52.98	4.00e-127	448.00
IUUC-Ola-087094	Oryzias latipes	90.06	0.00e+00	842.00
IUUC-Oga-088911	Otolemur garnettii	92.76	0.00e+00	946.00
IUUC-Oar-089508	Ovis aries	92.35	0.00e+00	944.00
IUUC-Ptr-090967	Pan troglodytes	79.80	2.00e-180	624.00
IUUC-Pan-092147	Papio anubis	92.00	0.00e+00	942.00
IUUC-Psi-093702	Pelodiscus sinensis	92.99	0.00e+00	948.00
IUUC-Pma-094581	Petromyzon marinus	82.18	0.00e+00	799.00
IUUC-Pfo-096309	Poecilia formosa	91.57	0.00e+00	892.00
IUUC-Pab-098762	Pongo abelii	75.80	0.00e+00	724.00
IUUC-Pop-098924	Populus trichocarpa	56.50	1.00e-133	469.00
IUUC-Pca-100565	Procavia capensis	88.03	0.00e+00	848.00
IUUC-Ppe-101924	Prunus persica	57.05	3.00e-137	481.00
IUUC-Pva-102602	Pteropus vampyrus	89.98	0.00e+00	901.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	44.80	3.00e-114	405.00
IUUC-Rno-105028	Rattus norvegicus	91.95	0.00e+00	939.00
IUUC-Sha-107107	Sarcophilus harrisii	78.97	0.00e+00	788.00
IUUC-Smo-108878	Selaginella moellendorffii	58.64	1.00e-145	509.00
IUUC-Sly-111446	Solanum lycopersicum	55.72	1.00e-135	476.00
IUUC-Stu-112491	Solanum tuberosum	55.53	7.00e-135	473.00
IUUC-Sre-115222	Sporisorium reilianum	48.40	4.00e-132	464.00
IUUC-Ssc-116171	Sus scrofa	92.35	0.00e+00	944.00
IUUC-Tgu-116878	Taeniopygia guttata	82.18	0.00e+00	815.00
IUUC-Tni-119863	Tetraodon nigroviridis	90.56	0.00e+00	876.00
IUUC-Tca-121599	Theobroma cacao	56.06	4.00e-136	478.00
IUUC-Tbe-128056	Tupaia belangeri	86.56	1.00e-162	565.00
IUUC-Ttr-129055	Tursiops truncatus	91.00	0.00e+00	925.00
IUUC-Uma-129555	Ustilago maydis	48.21	4.00e-131	461.00
IUUC-Vvi-131749	Vitis vinifera	55.73	6.00e-136	477.00
IUUC-Xtr-132808	Xenopus tropicalis	88.73	0.00e+00	904.00
IUUC-Xma-133183	Xiphophorus maculatus	91.57	0.00e+00	892.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence