iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052615

Ensembl Protein ID

ENSLOCP00000015411.1

UniProt Accession

W5N452; W5N452_LEPOC

Genbank Protein ID

ENSLOCP00000015411

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01023107

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000012516.1	ENSLOCT00000015440.1	ENSLOCP00000015411.1
ENSLOCG00000012516.1	ENSLOCT00000015449.1	ENSLOCP00000015420.1
ENSLOCG00000012516.1	ENSLOCT00000015457.1	ENSLOCP00000015428.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.90e-26	91.2	32	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavspre.....llkalkkeaee 83
           Gl N   +N+C++NS+LQ+L+++  +r+ + + +++k+ e+       ++ ++l+++f++++ s++k v p++     l k++++e+ +
   Q: 32   GLINEpgQNSCFLNSALQVLWHLDIFRRSFRQLTSHKCMED------SCIFCALKSIFAQFQFSSEK-VLPSDalrsaLAKTFQDEQ-R 112
           77786668************************999999865......69************644444.4444333332555555444.5 PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           f+     Da E+++ +l +++ ++                    de +e+  + ++++ ++ F ++l +q++c++c+ +s    pf+++
   Q: 113  FQLGIMDDAAECFENILMRIHFHI-------------------ADETKEDICTAKHCIPHQKFAMTLFEQCVCNSCGATSDPL-PFIQM 181
           99**********************...................3455677899*************************99766.9**** PP
   S: 173  slpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
              ++  + +++             d++ +  ++ +  g+ +   ++c +k +  +++ +++ Pe++++ L +   s + +  e +  +
   Q: 182  VHYISTTSLCNQAirmlecrekPTPDMFGELLRNASTMGDLRNCPSNCGEKLR-IRRVLMNS-PEIITIGLVWD--SDHSDLAEDVIHS 266
           *****999998889999999998889999999999999988888889988885.66666665.**********9..4444555555555 PP
   S: 253  vefpleLdlsp..fctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvl 333
           + +   L l    + ++ ++k k+++ Y L+++v+++G     HY ++  ++k + W++fdD +V+e+  k+++v++ +     ++ +l
   Q: 267  LGTC--LRLGDlfYRVT-DDKAKQSELY-LVGMVCYYG----KHYSTFFFQTKIRrWMYFDDAHVKEIgpKWKDVVSRCIkghYQPLLL 347
           5555..55554213333.3333335566.*********....9******9988778************766899988554555555566 PP
   S: 334  fY 335
           +Y
   Q: 348  LY 349
           66 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSWKRNYFAS GSSGLQGIFT PRTMTSIAPS KGLINEPGQN SCFLNSALQV LWHLDIFRRS 60
FRQLTSHKCM EDSCIFCALK SIFAQFQFSS EKVLPSDALR SALAKTFQDE QRFQLGIMDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTTGAGAA GATGACCTGC AGAATGCTTG TCGGCCTAGC GGTTCCACAA GAGCGTGTGA 60
CGGTCCAGTA GGACACGGGG TGAGAACTGC AGCTCGGGAG AGCTTTCTAC AGTGTGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007330--MIT
IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000820	Aegilops tauschii	31.43	5.00e-19	89.00
IUUC-Aml-001414	Ailuropoda melanoleuca	67.63	0.00e+00	1026.00
IUUC-Apl-004044	Anas platyrhynchos	66.00	0.00e+00	1015.00
IUUC-Aca-004351	Anolis carolinensis	68.17	0.00e+00	1053.00
IUUC-Aly-005468	Arabidopsis lyrata	33.80	1.00e-42	169.00
IUUC-Ath-006682	Arabidopsis thaliana	34.01	3.00e-41	164.00
IUUC-Ame-011525	Astyanax mexicanus	74.65	0.00e+00	1229.00
IUUC-Bta-013344	Bos taurus	65.05	0.00e+00	1031.00
IUUC-Bdi-015058	Brachypodium distachyon	34.71	1.00e-44	175.00
IUUC-Bol-015670	Brassica oleracea	33.14	2.00e-39	157.00
IUUC-Bra-016731	Brassica rapa	33.33	2.00e-41	165.00
IUUC-Cja-018724	Callithrix jacchus	67.56	0.00e+00	1029.00
IUUC-Cfa-021222	Canis familiaris	67.38	0.00e+00	1064.00
IUUC-Cpo-021795	Cavia porcellus	66.88	0.00e+00	1051.00
IUUC-Cre-022697	Chlamydomonas reinhardtii	24.29	2.00e-18	89.70
IUUC-Csa-023262	Chlorocebus sabaeus	66.74	0.00e+00	1026.00
IUUC-Cho-024422	Choloepus hoffmanni	62.54	0.00e+00	968.00
IUUC-Cin-025752	Ciona intestinalis	69.42	4.00e-49	186.00
IUUC-Csv-026063	Ciona savignyi	54.91	1.00e-114	405.00
IUUC-Dre-028046	Danio rerio	59.22	0.00e+00	1453.00
IUUC-Dno-029417	Dasypus novemcinctus	65.64	0.00e+00	929.00
IUUC-Dme-032071	Drosophila melanogaster	50.83	7.00e-105	376.00
IUUC-Eca-033235	Equus caballus	66.88	0.00e+00	1013.00
IUUC-Fca-036070	Felis catus	67.24	0.00e+00	1028.00
IUUC-Fal-037089	Ficedula albicollis	65.48	0.00e+00	1154.00
IUUC-Gmo-038653	Gadus morhua	80.26	0.00e+00	645.00
IUUC-Gga-041241	Gallus gallus	65.69	0.00e+00	1153.00
IUUC-Gac-042157	Gasterosteus aculeatus	87.06	0.00e+00	728.00
IUUC-Ggo-045626	Gorilla gorilla	66.84	0.00e+00	1024.00
IUUC-Hsa-045767	Homo sapiens	66.95	0.00e+00	1028.00
IUUC-Hvu-047657	Hordeum vulgare	34.12	6.00e-45	176.00
IUUC-Itr-048187	Ictidomys tridecemlineatus	60.57	0.00e+00	1011.00
IUUC-Lch-049712	Latimeria chalumnae	91.43	0.00e+00	744.00
IUUC-Laf-054578	Loxodonta africana	87.70	0.00e+00	739.00
IUUC-Mcc-054696	Macaca mulatta	66.95	0.00e+00	1026.00
IUUC-Mga-059393	Meleagris gallopavo	86.23	3.00e-165	573.00
IUUC-Mmr-060701	Microcebus murinus	65.55	0.00e+00	1006.00
IUUC-Mdo-062433	Monodelphis domestica	67.63	0.00e+00	1064.00
IUUC-Mmu-063480	Mus musculus	60.47	0.00e+00	949.00
IUUC-Mpu-066404	Mustela putorius furo	66.13	0.00e+00	1050.00
IUUC-Mlu-067841	Myotis lucifugus	87.43	0.00e+00	740.00
IUUC-Nle-070110	Nomascus leucogenys	66.84	0.00e+00	1025.00
IUUC-Opr-070676	Ochotona princeps	62.89	0.00e+00	804.00
IUUC-Oan-073551	Ornithorhynchus anatinus	66.60	0.00e+00	1057.00
IUUC-Ocu-074729	Oryctolagus cuniculus	67.49	0.00e+00	1065.00
IUUC-Oba-075174	Oryza barthii	32.16	6.00e-37	150.00
IUUC-Ogl-077138	Oryza glaberrima	33.04	1.00e-41	166.00
IUUC-Ogu-078705	Oryza glumaepatula	32.16	6.00e-37	150.00
IUUC-Oin-079125	Oryza indica	33.04	1.00e-41	165.00
IUUC-Olo-080872	Oryza longistaminata	32.16	7.00e-37	149.00
IUUC-Ome-081864	Oryza meridionalis	32.16	9.00e-37	150.00
IUUC-Oni-082109	Oryza nivara	32.16	6.00e-37	150.00
IUUC-Opu-083823	Oryza punctata	33.04	4.00e-42	167.00
IUUC-Oru-084310	Oryza rufipogon	32.16	6.00e-37	150.00
IUUC-Osa-085583	Oryza sativa	33.04	7.00e-41	161.00
IUUC-Ola-086742	Oryzias latipes	84.47	0.00e+00	675.00
IUUC-Oga-088920	Otolemur garnettii	64.62	0.00e+00	1027.00
IUUC-Oar-089644	Ovis aries	64.57	0.00e+00	1031.00
IUUC-Ptr-091530	Pan troglodytes	66.31	0.00e+00	1027.00
IUUC-Pan-092190	Papio anubis	66.95	0.00e+00	1025.00
IUUC-Psi-094022	Pelodiscus sinensis	67.71	0.00e+00	1083.00
IUUC-Pma-094745	Petromyzon marinus	59.62	3.00e-136	477.00
IUUC-Pfo-096072	Poecilia formosa	85.23	0.00e+00	754.00
IUUC-Pab-097979	Pongo abelii	66.21	0.00e+00	1025.00
IUUC-Pca-101005	Procavia capensis	75.59	2.00e-174	607.00
IUUC-Pva-103125	Pteropus vampyrus	66.67	0.00e+00	1058.00
IUUC-Rno-105463	Rattus norvegicus	66.89	0.00e+00	1006.00
IUUC-Sha-107164	Sarcophilus harrisii	65.64	0.00e+00	982.00
IUUC-Sit-110021	Setaria italica	33.14	2.00e-39	158.00
IUUC-Sbi-114345	Sorghum bicolor	34.31	1.00e-43	172.00
IUUC-Ssc-116206	Sus scrofa	63.60	0.00e+00	975.00
IUUC-Tgu-116521	Taeniopygia guttata	89.01	0.00e+00	754.00
IUUC-Tru-118155	Takifugu rubripes	74.75	0.00e+00	635.00
IUUC-Tsy-118998	Tarsius syrichta	61.16	0.00e+00	919.00
IUUC-Tni-120257	Tetraodon nigroviridis	84.69	0.00e+00	706.00
IUUC-Tca-121692	Theobroma cacao	32.35	3.00e-39	157.00
IUUC-Tae-125674	Triticum aestivum	34.51	3.00e-46	181.00
IUUC-Tur-126027	Triticum urartu	34.51	6.00e-46	180.00
IUUC-Ttr-128290	Tursiops truncatus	64.73	0.00e+00	964.00
IUUC-Vpa-130213	Vicugna pacos	63.69	0.00e+00	981.00
IUUC-Xtr-131831	Xenopus tropicalis	65.12	0.00e+00	1090.00
IUUC-Xma-133409	Xiphophorus maculatus	62.83	0.00e+00	962.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence