iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011554

Ensembl Protein ID

ENSAMXP00000006863.1

UniProt Accession

W5KH01; W5KH01_ASTMX

Genbank Protein ID

ENSAMXP00000006863

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01102320

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000006693.1	ENSAMXT00000006863.1	ENSAMXP00000006863.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.90e-76	256.1	89	414
ULD/UDP/UBQ/UBQ_Other	1.00e-09	38.4	965	1028

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp..kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           +Gl+Nlg+tCY+N  LQ+ ++  elr++l   ++++ +  n   + +  +++++lq lf+ l++s++++++p+ l+kal+     +++ 
   Q: 89   VGLTNLGATCYVNTFLQVWFHNLELRRMLYMCQNSRAEGHNIesDYEPRTICEHLQYLFALLQNSNRRYIDPSGLVKALG-----LDTG 172
           6*****************************9666666555541155667******************************9.....7889 PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDaqEf + +l+ le++l                       +++k+ + +++i++ F gq++  ++c++c ++s   + f++l+l++
   Q: 173  QQQDAQEFSKLFLSLLEDTL-----------------------SKQKDPSLQNVIQQQFCGQFSYVTVCNQCSRSSALPSRFYELELNI 238
           9*******************.......................457889999************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           +g++     +l++c+ +f kee+l+g+n+yyce+c++kq a++++kl++lP++L l+L+Rf f+++ ++++k+n+ ++fp+ Ld+spf+
   Q: 239  QGHK-----NLTECITEFLKEEKLDGDNRYYCESCQSKQSATRRIKLHSLPPTLNLQLMRFVFDRQSGHKKKLNTFISFPEVLDMSPFL 322
           ****.....9******************************************************************************* PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg.......................st 329
           + ++e    k++YeL+av++H G s+ sGHY+a+v++ + + W++f+D+++++++ ++ +  t+                       ++
   Q: 323  EAKDE----KCTYELSAVLIHRGvSAYSGHYIAHVRDARTNdWYKFNDEEIEKMEGKKLQLGTEedlaetvksqtrkpksskgyhcsRN 407
           *9554....79**************************77767***************999988899*********************** PP
   S: 330  aYvlfYk 336
           aY+l+Yk
   Q: 408  AYMLVYK 414
           ******8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           e  l v+   t +eLK +i +++++ p +q+L ++G++L +d  tL+++g++++s i+l  +++
   Q: 965  EKALIVSANQTLKELKIQIMHAFSVAPFDQNLSIDGRCLtDDSATLGSLGVFPESIICLKADEP 1028
           5556689999**********************************************99987765 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MAPRIQLEKA AWRWVDSVRP EDITQEHIDL AYRIAVPACK RGTCRRNCKG NPNCLVGIGE 60
HLWLGEIDEN TFHNIDDPNS ERRDKNTFVG LTNLGATCYV NTFLQVWFHN LELRRMLYMC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGTCATCG CGTACGCCTC CAACAAGTTT GAAAGTGAGG AAGGTAAAAA AATATATAAT 60
TTAAAAACAG AGCGAAGGGC GCTAAATACA AACACCCCCC GAATAAAATG TGAACAGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	34.14	5.00e-79	289.00
IUUC-Aml-001357	Ailuropoda melanoleuca	68.27	0.00e+00	1453.00
IUUC-Atr-002976	Amborella trichopoda	29.05	3.00e-82	300.00
IUUC-Apl-003773	Anas platyrhynchos	67.11	0.00e+00	1292.00
IUUC-Aca-004466	Anolis carolinensis	70.89	0.00e+00	771.00
IUUC-Aly-006249	Arabidopsis lyrata	27.69	3.00e-72	267.00
IUUC-Ath-006700	Arabidopsis thaliana	32.28	6.00e-83	302.00
IUUC-Bta-012573	Bos taurus	68.39	0.00e+00	1465.00
IUUC-Bdi-014149	Brachypodium distachyon	33.33	2.00e-83	304.00
IUUC-Bol-016289	Brassica oleracea	27.38	6.00e-84	305.00
IUUC-Bra-017494	Brassica rapa	33.54	3.00e-84	306.00
IUUC-Cel-018662	Caenorhabditis elegans	29.71	3.00e-28	121.00
IUUC-Cja-019991	Callithrix jacchus	67.72	0.00e+00	1462.00
IUUC-Cfa-020294	Canis familiaris	68.33	0.00e+00	1477.00
IUUC-Cpo-021706	Cavia porcellus	68.44	0.00e+00	1404.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	36.69	8.00e-43	170.00
IUUC-Csa-023931	Chlorocebus sabaeus	68.61	0.00e+00	1477.00
IUUC-Cho-024566	Choloepus hoffmanni	62.59	6.00e-108	385.00
IUUC-Cin-025307	Ciona intestinalis	49.66	3.00e-81	294.00
IUUC-Csv-026006	Ciona savignyi	36.50	7.00e-157	548.00
IUUC-Cne-027065	Cryptococcus neoformans	33.85	5.00e-69	256.00
IUUC-Dre-027624	Danio rerio	84.40	0.00e+00	1845.00
IUUC-Dno-029633	Dasypus novemcinctus	70.06	0.00e+00	934.00
IUUC-Dor-030809	Dipodomys ordii	54.67	0.00e+00	845.00
IUUC-Ete-032818	Echinops telfairi	71.15	0.00e+00	738.00
IUUC-Eca-033692	Equus caballus	68.33	0.00e+00	1471.00
IUUC-Eeu-035185	Erinaceus europaeus	68.55	7.00e-113	402.00
IUUC-Fca-035676	Felis catus	68.21	0.00e+00	1473.00
IUUC-Fal-036913	Ficedula albicollis	67.42	0.00e+00	1444.00
IUUC-Gmo-038532	Gadus morhua	73.74	0.00e+00	1593.00
IUUC-Gga-041041	Gallus gallus	68.37	0.00e+00	1447.00
IUUC-Gac-042570	Gasterosteus aculeatus	75.60	0.00e+00	1649.00
IUUC-Gma-044136	Glycine max	27.86	5.00e-86	313.00
IUUC-Ggo-045367	Gorilla gorilla	65.60	0.00e+00	1385.00
IUUC-Hsa-046019	Homo sapiens	68.52	0.00e+00	1477.00
IUUC-Hvu-047303	Hordeum vulgare	35.59	1.00e-65	243.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	67.87	0.00e+00	1461.00
IUUC-Lch-049989	Latimeria chalumnae	69.74	0.00e+00	1507.00
IUUC-Lpe-051612	Leersia perrieri	33.70	5.00e-79	289.00
IUUC-Loc-052756	Lepisosteus oculatus	76.45	0.00e+00	1707.00
IUUC-Laf-054043	Loxodonta africana	67.38	0.00e+00	1462.00
IUUC-Mcc-054986	Macaca mulatta	67.57	0.00e+00	1461.00
IUUC-Meu-056228	Macropus eugenii	53.12	2.00e-165	576.00
IUUC-Mtr-058610	Medicago truncatula	29.82	7.00e-78	285.00
IUUC-Mga-059896	Meleagris gallopavo	67.87	0.00e+00	1359.00
IUUC-Mvi-060269	Microbotryum violaceum	38.90	3.00e-66	247.00
IUUC-Mmr-060887	Microcebus murinus	68.52	0.00e+00	1474.00
IUUC-Mdo-062506	Monodelphis domestica	68.71	0.00e+00	1473.00
IUUC-Mmu-063642	Mus musculus	67.01	0.00e+00	1454.00
IUUC-Mac-064896	Musa acuminata	32.61	3.00e-79	290.00
IUUC-Mpu-066194	Mustela putorius furo	68.52	0.00e+00	1469.00
IUUC-Mlu-067233	Myotis lucifugus	67.94	0.00e+00	1462.00
IUUC-Nle-069052	Nomascus leucogenys	67.75	0.00e+00	1461.00
IUUC-Opr-070890	Ochotona princeps	71.00	0.00e+00	906.00
IUUC-Ont-071450	Oreochromis niloticus	72.38	0.00e+00	1554.00
IUUC-Oan-073252	Ornithorhynchus anatinus	62.34	0.00e+00	728.00
IUUC-Ocu-073796	Oryctolagus cuniculus	68.24	0.00e+00	1241.00
IUUC-Oba-075563	Oryza barthii	33.65	3.00e-80	293.00
IUUC-Obr-076394	Oryza brachyantha	33.44	4.00e-81	296.00
IUUC-Ogl-077339	Oryza glaberrima	40.62	5.00e-43	167.00
IUUC-Ogu-079007	Oryza glumaepatula	32.70	2.00e-73	270.00
IUUC-Oin-079997	Oryza indica	33.65	2.00e-80	294.00
IUUC-Olo-080364	Oryza longistaminata	33.65	3.00e-80	293.00
IUUC-Ome-081165	Oryza meridionalis	33.12	2.00e-74	274.00
IUUC-Oni-083026	Oryza nivara	33.65	2.00e-80	294.00
IUUC-Opu-083284	Oryza punctata	34.11	2.00e-73	270.00
IUUC-Oru-084797	Oryza rufipogon	33.96	3.00e-80	293.00
IUUC-Osa-086221	Oryza sativa	40.62	5.00e-43	167.00
IUUC-Ola-086568	Oryzias latipes	75.44	0.00e+00	1635.00
IUUC-Oga-088687	Otolemur garnettii	67.97	0.00e+00	1465.00
IUUC-Oar-090345	Ovis aries	68.50	0.00e+00	1397.00
IUUC-Ptr-090734	Pan troglodytes	68.52	0.00e+00	1476.00
IUUC-Pan-091704	Papio anubis	66.13	0.00e+00	1407.00
IUUC-Psi-092937	Pelodiscus sinensis	66.17	0.00e+00	1219.00
IUUC-Ppa-095808	Physcomitrella patens	28.68	6.00e-72	266.00
IUUC-Pab-098129	Pongo abelii	68.52	0.00e+00	1476.00
IUUC-Pop-099494	Populus trichocarpa	32.35	1.00e-78	288.00
IUUC-Pca-100647	Procavia capensis	76.06	1.00e-156	547.00
IUUC-Ppe-102091	Prunus persica	32.24	6.00e-82	299.00
IUUC-Pva-102719	Pteropus vampyrus	68.14	0.00e+00	1460.00
IUUC-Rno-105363	Rattus norvegicus	68.33	0.00e+00	1478.00
IUUC-Sha-107620	Sarcophilus harrisii	65.96	0.00e+00	1351.00
IUUC-Smo-109487	Selaginella moellendorffii	27.38	9.00e-82	298.00
IUUC-Sit-110683	Setaria italica	30.70	3.00e-86	313.00
IUUC-Sly-111377	Solanum lycopersicum	30.98	4.00e-80	293.00
IUUC-Stu-111969	Solanum tuberosum	31.65	1.00e-68	254.00
IUUC-Sar-113099	Sorex araneus	67.93	0.00e+00	1236.00
IUUC-Sbi-113833	Sorghum bicolor	43.67	8.00e-60	223.00
IUUC-Ssc-115279	Sus scrofa	60.77	0.00e+00	905.00
IUUC-Tgu-117519	Taeniopygia guttata	64.64	0.00e+00	1294.00
IUUC-Tru-117651	Takifugu rubripes	74.31	0.00e+00	1641.00
IUUC-Tsy-119201	Tarsius syrichta	66.70	0.00e+00	1317.00
IUUC-Tni-120840	Tetraodon nigroviridis	75.67	0.00e+00	1665.00
IUUC-Tca-121674	Theobroma cacao	28.29	1.00e-85	311.00
IUUC-Tae-125814	Triticum aestivum	33.66	3.00e-80	293.00
IUUC-Tur-126599	Triticum urartu	34.14	7.00e-79	289.00
IUUC-Tbe-127782	Tupaia belangeri	61.01	0.00e+00	1243.00
IUUC-Ttr-128312	Tursiops truncatus	67.39	0.00e+00	1444.00
IUUC-Vpa-130348	Vicugna pacos	68.41	0.00e+00	1397.00
IUUC-Vvi-131353	Vitis vinifera	31.22	5.00e-79	289.00
IUUC-Xtr-132172	Xenopus tropicalis	61.47	0.00e+00	1176.00
IUUC-Xma-133263	Xiphophorus maculatus	75.35	0.00e+00	1589.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence