iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133618

Ensembl Protein ID

ENSXMAP00000002601.1

UniProt Accession

M3ZK59; M3ZK59_XIPMA

Genbank Protein ID

ENSXMAP00000002601

Protein Name

Nitric oxide synthase-interacting protein

Genbank Nucleotide ID

AGAJ01031795

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000002594.1	ENSXMAT00000002606.1	ENSXMAP00000002601.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.10e-15	57.5	40	99

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk.......tcPvtrqplteed 54
           + ++ +C +sl++ +dPvv+p+G+ y++++I +++ ++++          + +q l++++
   Q: 40   IKDFDCCCLSLQPCQDPVVTPDGYLYEKQAILEYILHQKTeiakkmkAYEKQKQALKSTN 99
           567789*****************************8888755555445555666665554 PP

Organism

Xiphophorus maculatus

Functional Description
(View)

Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.

Protein Sequence
(Fasta)

MTRHGKNCTA GAVYTYHEKR KDTAASGYGT QSVRLGKDAI KDFDCCCLSL QPCQDPVVTP 60
DGYLYEKQAI LEYILHQKTE IAKKMKAYEK QKQALKSTNQ LESKSEERQR VERFKTSENS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTCGAC ATGGGAAGAA CTGCACAGCC GGAGCTGTTT ATACTTACCA TGAGAAGAGG 60
AAGGACACAG GTGAGCTTCA CTGAGCAGCA GCATCTGTTG GCTAATGGTG TTACTAATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF15906--zf-NOSIP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0050999--P:regulation of nitric-oxide synthase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000769	Aegilops tauschii	48.84	4.00e-17	82.80
IUUC-Aml-002069	Ailuropoda melanoleuca	63.06	2.00e-112	399.00
IUUC-Atr-002661	Amborella trichopoda	30.00	4.00e-27	115.00
IUUC-Aca-004630	Anolis carolinensis	67.11	3.00e-117	414.00
IUUC-Aly-006316	Arabidopsis lyrata	28.95	2.00e-26	113.00
IUUC-Ath-007000	Arabidopsis thaliana	28.29	7.00e-26	110.00
IUUC-Ame-011874	Astyanax mexicanus	77.60	2.00e-125	441.00
IUUC-Bgr-012090	Blumeria graminis	23.67	1.00e-04	40.80
IUUC-Bta-012956	Bos taurus	65.79	2.00e-116	411.00
IUUC-Bci-013897	Botrytis cinerea	36.25	8.00e-08	51.20
IUUC-Bdi-014968	Brachypodium distachyon	30.82	3.00e-34	139.00
IUUC-Bol-015578	Brassica oleracea	30.16	2.00e-29	123.00
IUUC-Bra-017234	Brassica rapa	30.16	2.00e-29	123.00
IUUC-Cel-018637	Caenorhabditis elegans	63.51	5.00e-28	117.00
IUUC-Cja-019632	Callithrix jacchus	66.78	3.00e-117	414.00
IUUC-Cfa-020192	Canis familiaris	65.13	2.00e-115	409.00
IUUC-Cpo-021939	Cavia porcellus	65.13	8.00e-116	409.00
IUUC-Cre-023005	Chlamydomonas reinhardtii	32.08	6.00e-36	144.00
IUUC-Csa-023802	Chlorocebus sabaeus	65.46	3.00e-115	408.00
IUUC-Cho-024637	Choloepus hoffmanni	50.31	4.00e-36	144.00
IUUC-Cin-025180	Ciona intestinalis	52.61	2.00e-84	305.00
IUUC-Csv-026206	Ciona savignyi	53.90	8.00e-42	162.00
IUUC-Cgl-026696	Colletotrichum gloeosporioides	32.61	5.00e-09	55.10
IUUC-Cne-026827	Cryptococcus neoformans	36.47	3.00e-07	49.30
IUUC-Dre-028092	Danio rerio	80.26	1.00e-131	462.00
IUUC-Dno-029501	Dasypus novemcinctus	60.91	8.00e-101	360.00
IUUC-Dor-030542	Dipodomys ordii	65.79	1.00e-115	409.00
IUUC-Dme-031734	Drosophila melanogaster	45.28	1.00e-76	279.00
IUUC-Eca-033577	Equus caballus	65.46	2.00e-115	408.00
IUUC-Fca-035761	Felis catus	65.79	3.00e-116	410.00
IUUC-Gmo-038523	Gadus morhua	72.40	3.00e-69	254.00
IUUC-Ggr-040087	Gaeumannomyces graminis	35.90	3.00e-08	52.40
IUUC-Gac-042621	Gasterosteus aculeatus	77.99	5.00e-128	450.00
IUUC-Gma-042698	Glycine max	30.29	3.00e-31	129.00
IUUC-Ggo-045357	Gorilla gorilla	65.79	8.00e-116	409.00
IUUC-Hsa-046195	Homo sapiens	65.79	8.00e-116	409.00
IUUC-Hvu-047174	Hordeum vulgare	30.82	9.00e-34	137.00
IUUC-Itr-048487	Ictidomys tridecemlineatus	64.47	1.00e-115	409.00
IUUC-Lch-050569	Latimeria chalumnae	65.27	3.00e-105	374.00
IUUC-Lpe-050992	Leersia perrieri	33.02	1.00e-20	94.40
IUUC-Loc-052522	Lepisosteus oculatus	73.93	2.00e-118	418.00
IUUC-Laf-053397	Loxodonta africana	65.79	5.00e-115	407.00
IUUC-Mcc-054681	Macaca mulatta	65.79	7.00e-116	410.00
IUUC-Meu-056723	Macropus eugenii	63.49	4.00e-114	404.00
IUUC-Mor-056961	Magnaporthe oryzae	33.01	4.00e-09	55.80
IUUC-Mpo-057359	Magnaporthe poae	27.27	3.00e-06	45.80
IUUC-Mtr-058063	Medicago truncatula	30.29	5.00e-33	134.00
IUUC-Mla-059004	Melampsora laricipopulina	28.98	3.00e-22	99.00
IUUC-Mvi-060460	Microbotryum violaceum	28.70	1.00e-21	97.10
IUUC-Mmr-060847	Microcebus murinus	65.79	5.00e-116	410.00
IUUC-Mdo-062480	Monodelphis domestica	63.73	4.00e-114	404.00
IUUC-Mmu-063809	Mus musculus	64.14	7.00e-112	396.00
IUUC-Mac-064870	Musa acuminata	31.10	4.00e-35	141.00
IUUC-Mpu-066322	Mustela putorius furo	66.45	2.00e-116	412.00
IUUC-Mlu-067556	Myotis lucifugus	65.79	4.00e-117	414.00
IUUC-Ncr-068898	Neurospora crassa	33.33	5.00e-06	45.40
IUUC-Nle-070049	Nomascus leucogenys	65.79	9.00e-116	409.00
IUUC-Opr-070972	Ochotona princeps	66.12	2.00e-116	411.00
IUUC-Ont-071682	Oreochromis niloticus	83.44	3.00e-137	480.00
IUUC-Oan-073296	Ornithorhynchus anatinus	89.83	6.00e-30	122.00
IUUC-Ocu-074218	Oryctolagus cuniculus	63.60	7.00e-100	356.00
IUUC-Oba-075284	Oryza barthii	30.82	1.00e-32	133.00
IUUC-Obr-076651	Oryza brachyantha	30.49	1.00e-34	139.00
IUUC-Ogl-077899	Oryza glaberrima	30.82	1.00e-32	133.00
IUUC-Ogu-078477	Oryza glumaepatula	31.15	7.00e-33	134.00
IUUC-Oin-080011	Oryza indica	30.82	1.00e-32	133.00
IUUC-Olo-080545	Oryza longistaminata	29.96	9.00e-25	107.00
IUUC-Ome-081543	Oryza meridionalis	30.82	1.00e-32	133.00
IUUC-Oni-082955	Oryza nivara	30.82	1.00e-32	133.00
IUUC-Opu-083565	Oryza punctata	30.82	6.00e-33	134.00
IUUC-Oru-084474	Oryza rufipogon	30.82	1.00e-32	133.00
IUUC-Osa-085913	Oryza sativa	30.82	1.00e-32	133.00
IUUC-Ola-086851	Oryzias latipes	81.25	2.00e-142	498.00
IUUC-Olu-087724	Ostreococcus lucimarinus	29.13	5.00e-11	61.60
IUUC-Oga-087970	Otolemur garnettii	65.90	2.00e-114	404.00
IUUC-Oar-089756	Ovis aries	64.14	5.00e-110	390.00
IUUC-Ptr-091485	Pan troglodytes	64.80	2.00e-112	398.00
IUUC-Pan-091832	Papio anubis	65.79	9.00e-116	409.00
IUUC-Pma-094551	Petromyzon marinus	61.24	4.00e-101	360.00
IUUC-Ppa-095255	Physcomitrella patens	29.77	3.00e-29	122.00
IUUC-Pfo-096373	Poecilia formosa	89.54	4.00e-156	543.00
IUUC-Pab-098247	Pongo abelii	65.79	1.00e-115	409.00
IUUC-Pop-099186	Populus trichocarpa	30.82	2.00e-32	132.00
IUUC-Pca-100677	Procavia capensis	60.79	1.00e-88	319.00
IUUC-Ppe-101403	Prunus persica	29.43	3.00e-30	125.00
IUUC-Pva-103000	Pteropus vampyrus	65.46	4.00e-116	410.00
IUUC-Pgr-103663	Puccinia graminis	29.32	9.00e-25	107.00
IUUC-Ptt-103712	Puccinia triticina	33.85	3.00e-07	48.90
IUUC-Pyt-104579	Pyrenophora triticirepentis	31.25	4.00e-07	48.90
IUUC-Rno-106069	Rattus norvegicus	64.47	1.00e-112	399.00
IUUC-Sha-106553	Sarcophilus harrisii	63.73	9.00e-114	402.00
IUUC-Smo-108874	Selaginella moellendorffii	32.00	8.00e-35	140.00
IUUC-Sit-110307	Setaria italica	31.15	3.00e-31	129.00
IUUC-Sly-111094	Solanum lycopersicum	31.10	7.00e-34	137.00
IUUC-Stu-112363	Solanum tuberosum	31.10	6.00e-34	137.00
IUUC-Sar-113480	Sorex araneus	64.80	5.00e-112	397.00
IUUC-Sbi-113939	Sorghum bicolor	31.15	3.00e-33	135.00
IUUC-Ssc-115644	Sus scrofa	66.12	2.00e-116	411.00
IUUC-Tru-118781	Takifugu rubripes	75.90	2.00e-133	468.00
IUUC-Tni-119672	Tetraodon nigroviridis	77.01	6.00e-36	141.00
IUUC-Tca-121795	Theobroma cacao	31.10	2.00e-34	139.00
IUUC-Tre-122037	Trichoderma reesei	31.17	1.00e-06	47.40
IUUC-Tvi-122524	Trichoderma virens	23.51	3.00e-11	62.40
IUUC-Tae-122828	Triticum aestivum	30.49	1.00e-33	136.00
IUUC-Tur-126387	Triticum urartu	30.34	8.00e-27	114.00
IUUC-Tme-127111	Tuber melanosporum	35.71	8.00e-08	51.20
IUUC-Tbe-127839	Tupaia belangeri	31.25	1.00e-03	37.40
IUUC-Ttr-128227	Tursiops truncatus	65.79	4.00e-116	410.00
IUUC-Vda-129924	Verticillium dahliae	24.36	2.00e-13	69.70
IUUC-Vpa-130802	Vicugna pacos	71.91	5.00e-34	137.00
IUUC-Vvi-131105	Vitis vinifera	31.31	1.00e-33	137.00
IUUC-Xtr-132830	Xenopus tropicalis	64.26	2.00e-114	405.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence