iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lma-053112

Ensembl Protein ID

CBX93963

UniProt Accession

E4ZRW6; E4ZRW6_LEPMJ

Genbank Protein ID

CBX93963.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

FP929116

Gene Name

LEMA_P036370.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
LEMA_P036370.1	CBX93963	CBX93963

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.60e-62	209.2	18	554

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagg..lGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           YDRQ+rlwG+++q +l+++++ll++ g+  +G+E+lKnLvl Gvg++t+ D + v+ ++l+ +F++++++ g  +Ae +++ lkelnpdv++ +++e+i+ 
   Q: 18   YDRQLRLWGATGQTALENSHILLLNSGPgvVGVETLKNLVLPGVGHFTIQDSAIVSEADLGVNFFLEDQHLGGYRAEHTCNCLKELNPDVEGHFVTEPIES 118
           ***********************9887666*********************************************************************** PP
   S: 100  leeeivFfkkfdvVvlaldnrea.rrkvnrlclnarvpliesgtlGllGqvrviik.gltecyscsd....dppqktiPfctlketpn...........aa 183
             ++   ++ ++++++    r    +++++   +a +pl+ + + G++++ +v+++  +++ + ++d     +++   P+++l ++ +           ++
   Q: 119  WLQQPKVLEPYTLIIAVAPIRPGlLTRLAEHASAALIPLFYIHSVGFYSHFSVHLPpAFPIVDTHPDagttSDLRIVRPWPELVQYAEektagldsmkpED 219
           *999779999*9999887777641568***************************9726788888888***9**************98888888888988** PP
   S: 184  ehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv..... 274
           + ++++++l+ ++lee+++ +e++ +++++ek+e+++ v++++++      eenf+ea+ +++k +++ +  + +k+++  +ec  +++++++fwv     
   Q: 220  HGHVPYIALLLHFLEEWKKTHEGNLPSNYKEKLEFRKTVEQAARTdtpeGGEENFDEAVGAVLKLLNPPEVRGaVKEIFTAPECLLIRQDSPSFWVianav 320
           ********************************************955555578****************99999*************************** PP
   S: 275  ...................................................................sfcsnaealq....................vpek 288
                                                                               fc+na+ ++                    + ++
   Q: 321  glfytkygvlpvpgsvpdmkarsadyiqlqnvykskarkdlaevvesvrflernanrstviqekdieAFCKNAAHIKlmrgrpfhvmqagqkvswrdRAKS 421
           *******************************************************************9999999999777766666555544332222233 PP
   S: 289  vekdeevvkasap.....lylllralerfekkkgrk.....pgelsfekdddsavdlvtaaanlra............eslgiep.kldddlikeiagnii 366
            ++ ++      p     lyl+++a ++  ++++++     p ++  e d++   + +t +a  +             e+  ++    ++++++e+++ + 
   Q: 422  LAQTMTF-----PeslvpLYLAFLAWDQYVATHDKDglggaP-GVPGETDQPLDTEKLTGIALQILedlvkeahadidEDELSKVtTQTREFVAEMVRAGG 516
           3333333.....244666999999999887777665222223.5666777776666666666444467777777777755555555699************ PP
   S: 367  paiattnavvgGlaaqEviKvvsgkfeplknfflfdae 404
           ++++ + a+ gG+++qE+iKv++++++p++n+ +fd++
   Q: 517  AELHNIGAMTGGMVSQEIIKVITEQYVPVDNTCVFDGI 554
           ***********************************986 PP

Organism

Leptosphaeria maculans

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MADLPPPVQG PTAKEKKYDR QLRLWGATGQ TALENSHILL LNSGPGVVGV ETLKNLVLPG 60
VGHFTIQDSA IVSEADLGVN FFLEDQHLGG YRAEHTCNCL KELNPDVEGH FVTEPIESWL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGATC TCCCTCCTCC TGTGCAGGGG CCCACCGCCA AGGAGAAGAA GTAGGCCGTC 60
TCCAATCCAC AGAGCTCTCT CGTTCGCCCA CTAAGAAACG CAGGTACGAC CGACAACTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	32.68	2.00e-73	268.00
IUUC-Aml-002333	Ailuropoda melanoleuca	34.98	4.00e-87	313.00
IUUC-Atr-002644	Amborella trichopoda	32.97	2.00e-69	254.00
IUUC-Apl-003446	Anas platyrhynchos	35.64	7.00e-80	289.00
IUUC-Aca-004450	Anolis carolinensis	32.69	1.00e-80	292.00
IUUC-Aly-005466	Arabidopsis lyrata	33.81	1.00e-78	285.00
IUUC-Ath-006692	Arabidopsis thaliana	33.87	2.00e-79	288.00
IUUC-Ago-007900	Ashbya gossypii	28.39	3.00e-27	114.00
IUUC-Acl-008333	Aspergillus clavatus	50.00	2.00e-150	523.00
IUUC-Afl-008529	Aspergillus flavus	51.06	3.00e-152	530.00
IUUC-Afu-009071	Aspergillus fumigatus	49.56	4.00e-149	519.00
IUUC-Ani-009443	Aspergillus nidulans	48.62	1.00e-142	498.00
IUUC-Ang-009669	Aspergillus niger	48.96	1.00e-153	534.00
IUUC-Aor-009914	Aspergillus oryzae	50.09	7.00e-151	525.00
IUUC-Ate-010450	Aspergillus terreus	49.91	6.00e-149	519.00
IUUC-Ame-011183	Astyanax mexicanus	34.29	2.00e-85	307.00
IUUC-Bgr-012111	Blumeria graminis	44.36	2.00e-122	431.00
IUUC-Bta-012583	Bos taurus	34.76	5.00e-89	320.00
IUUC-Bci-013892	Botrytis cinerea	46.49	3.00e-131	460.00
IUUC-Bdi-014592	Brachypodium distachyon	32.85	9.00e-71	259.00
IUUC-Bol-015487	Brassica oleracea	34.59	6.00e-79	286.00
IUUC-Bra-017506	Brassica rapa	34.13	2.00e-78	284.00
IUUC-Cel-018456	Caenorhabditis elegans	30.91	2.00e-62	231.00
IUUC-Cja-020007	Callithrix jacchus	35.56	2.00e-87	314.00
IUUC-Cfa-020324	Canis familiaris	35.58	5.00e-89	320.00
IUUC-Cpo-022248	Cavia porcellus	34.68	9.00e-49	186.00
IUUC-Csa-023149	Chlorocebus sabaeus	32.51	2.00e-63	234.00
IUUC-Cho-024537	Choloepus hoffmanni	29.01	4.00e-49	187.00
IUUC-Cin-025763	Ciona intestinalis	32.69	1.00e-76	278.00
IUUC-Csv-026113	Ciona savignyi	32.38	6.00e-78	283.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	48.92	3.00e-102	363.00
IUUC-Cne-026884	Cryptococcus neoformans	31.53	9.00e-59	219.00
IUUC-Cme-027210	Cyanidioschyzon merolae	19.61	9.00e-16	76.60
IUUC-Dre-028140	Danio rerio	34.88	9.00e-88	315.00
IUUC-Dno-030033	Dasypus novemcinctus	37.34	4.00e-78	283.00
IUUC-Dor-030513	Dipodomys ordii	52.78	2.00e-24	105.00
IUUC-Dse-031536	Dothistroma septosporum	52.99	3.00e-180	623.00
IUUC-Dme-031683	Drosophila melanogaster	33.45	9.00e-76	276.00
IUUC-Ete-032420	Echinops telfairi	32.90	2.00e-68	251.00
IUUC-Eca-033992	Equus caballus	32.21	7.00e-62	229.00
IUUC-Eeu-034713	Erinaceus europaeus	55.45	1.00e-25	109.00
IUUC-Fca-036548	Felis catus	35.75	2.00e-88	318.00
IUUC-Fal-037600	Ficedula albicollis	35.23	2.00e-78	285.00
IUUC-Fox-038037	Fusarium oxysporum	42.63	4.00e-129	453.00
IUUC-Fso-038387	Fusarium solani	42.91	1.00e-131	461.00
IUUC-Gmo-038562	Gadus morhua	33.81	6.00e-85	306.00
IUUC-Ggr-040005	Gaeumannomyces graminis	45.88	8.00e-134	468.00
IUUC-Gga-041129	Gallus gallus	35.60	1.00e-85	308.00
IUUC-Gac-042558	Gasterosteus aculeatus	34.29	3.00e-84	303.00
IUUC-Gma-043610	Glycine max	32.50	5.00e-75	273.00
IUUC-Ggo-045611	Gorilla gorilla	35.68	4.00e-87	313.00
IUUC-Hsa-046563	Homo sapiens	35.69	1.00e-87	315.00
IUUC-Hvu-047790	Hordeum vulgare	29.70	2.00e-42	164.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	35.04	2.00e-87	314.00
IUUC-Kpa-049309	Komagataella pastoris	33.09	6.00e-70	256.00
IUUC-Lch-050038	Latimeria chalumnae	34.51	2.00e-81	295.00
IUUC-Lpe-051535	Leersia perrieri	31.02	6.00e-54	203.00
IUUC-Loc-051917	Lepisosteus oculatus	33.68	5.00e-80	290.00
IUUC-Laf-053690	Loxodonta africana	35.83	2.00e-88	317.00
IUUC-Mcc-055117	Macaca mulatta	34.97	3.00e-84	304.00
IUUC-Meu-056761	Macropus eugenii	28.20	4.00e-56	210.00
IUUC-Mor-057230	Magnaporthe oryzae	44.97	9.00e-133	465.00
IUUC-Mpo-057514	Magnaporthe poae	46.21	1.00e-128	451.00
IUUC-Mtr-058551	Medicago truncatula	30.20	2.00e-69	255.00
IUUC-Mla-059183	Melampsora laricipopulina	32.94	2.00e-81	295.00
IUUC-Mga-060144	Meleagris gallopavo	35.32	1.00e-82	298.00
IUUC-Mvi-060221	Microbotryum violaceum	38.06	9.00e-67	246.00
IUUC-Mmr-061325	Microcebus murinus	34.86	6.00e-84	303.00
IUUC-Mdo-062532	Monodelphis domestica	34.22	1.00e-84	305.00
IUUC-Mmu-063956	Mus musculus	35.40	5.00e-90	323.00
IUUC-Mac-064521	Musa acuminata	33.75	1.00e-74	272.00
IUUC-Mpu-066716	Mustela putorius furo	34.90	4.00e-79	287.00
IUUC-Mlu-067459	Myotis lucifugus	36.03	5.00e-90	323.00
IUUC-Nfi-068245	Neosartorya fischeri	50.17	6.00e-151	525.00
IUUC-Ncr-068910	Neurospora crassa	46.96	3.00e-144	503.00
IUUC-Nle-070034	Nomascus leucogenys	34.24	7.00e-80	289.00
IUUC-Opr-070552	Ochotona princeps	32.83	7.00e-69	253.00
IUUC-Ont-071426	Oreochromis niloticus	34.77	2.00e-87	314.00
IUUC-Oan-073389	Ornithorhynchus anatinus	32.06	3.00e-58	217.00
IUUC-Ocu-074911	Oryctolagus cuniculus	35.22	7.00e-88	316.00
IUUC-Oba-075437	Oryza barthii	32.55	5.00e-63	233.00
IUUC-Obr-076684	Oryza brachyantha	32.31	7.00e-59	219.00
IUUC-Ogl-077170	Oryza glaberrima	32.55	5.00e-63	233.00
IUUC-Ogu-078844	Oryza glumaepatula	32.02	3.00e-56	211.00
IUUC-Oin-079105	Oryza indica	32.55	2.00e-63	235.00
IUUC-Olo-080943	Oryza longistaminata	30.67	4.00e-50	190.00
IUUC-Oni-082891	Oryza nivara	31.47	4.00e-57	214.00
IUUC-Opu-083457	Oryza punctata	32.91	7.00e-63	233.00
IUUC-Oru-084960	Oryza rufipogon	30.67	5.00e-50	190.00
IUUC-Osa-085358	Oryza sativa	32.37	4.00e-63	233.00
IUUC-Ola-086420	Oryzias latipes	32.99	2.00e-54	204.00
IUUC-Olu-087625	Ostreococcus lucimarinus	29.22	8.00e-48	183.00
IUUC-Oga-088810	Otolemur garnettii	34.76	6.00e-89	319.00
IUUC-Oar-089196	Ovis aries	34.57	6.00e-87	313.00
IUUC-Ptr-090617	Pan troglodytes	35.51	1.00e-87	315.00
IUUC-Pan-092761	Papio anubis	35.75	4.00e-89	320.00
IUUC-Psi-093191	Pelodiscus sinensis	33.21	1.00e-78	285.00
IUUC-Pma-094380	Petromyzon marinus	32.95	5.00e-72	263.00
IUUC-Pno-095084	Phaeosphaeria nodorum	72.82	0.00e+00	845.00
IUUC-Ppa-095875	Physcomitrella patens	32.14	7.00e-75	272.00
IUUC-Pfo-096467	Poecilia formosa	33.45	2.00e-86	311.00
IUUC-Pab-098255	Pongo abelii	36.97	6.00e-78	282.00
IUUC-Pop-099871	Populus trichocarpa	32.79	1.00e-75	275.00
IUUC-Pca-100807	Procavia capensis	38.07	2.00e-28	118.00
IUUC-Ppe-101280	Prunus persica	33.16	7.00e-77	279.00
IUUC-Pva-102333	Pteropus vampyrus	34.92	7.00e-81	292.00
IUUC-Pgr-103401	Puccinia graminis	29.26	9.00e-63	233.00
IUUC-Ptt-103889	Puccinia triticina	26.32	1.00e-57	215.00
IUUC-Pte-104355	Pyrenophora teres	79.93	0.00e+00	958.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	79.40	0.00e+00	947.00
IUUC-Rno-105810	Rattus norvegicus	35.16	9.00e-89	319.00
IUUC-Sha-106770	Sarcophilus harrisii	39.18	2.00e-49	187.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	30.31	4.00e-67	247.00
IUUC-Spo-108276	Schizosaccharomyces pombe	32.09	7.00e-73	266.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	48.23	5.00e-138	482.00
IUUC-Smo-109296	Selaginella moellendorffii	31.83	5.00e-72	263.00
IUUC-Sit-110157	Setaria italica	33.09	7.00e-76	276.00
IUUC-Sly-111105	Solanum lycopersicum	31.91	2.00e-75	274.00
IUUC-Stu-112469	Solanum tuberosum	32.62	9.00e-77	279.00
IUUC-Sar-113083	Sorex araneus	28.62	1.00e-25	108.00
IUUC-Sbi-113813	Sorghum bicolor	33.03	1.00e-74	272.00
IUUC-Sre-115058	Sporisorium reilianum	32.16	6.00e-75	273.00
IUUC-Tgu-116772	Taeniopygia guttata	34.95	3.00e-78	284.00
IUUC-Tru-118686	Takifugu rubripes	33.51	2.00e-84	304.00
IUUC-Tsy-119111	Tarsius syrichta	36.59	6.00e-42	163.00
IUUC-Tni-120231	Tetraodon nigroviridis	29.96	3.00e-71	261.00
IUUC-Tca-121491	Theobroma cacao	33.04	8.00e-72	262.00
IUUC-Tre-122103	Trichoderma reesei	44.64	1.00e-133	468.00
IUUC-Tvi-122672	Trichoderma virens	44.13	1.00e-130	457.00
IUUC-Tae-125684	Triticum aestivum	32.68	5.00e-74	270.00
IUUC-Tur-126487	Triticum urartu	31.70	8.00e-69	252.00
IUUC-Tme-127097	Tuber melanosporum	38.65	3.00e-101	360.00
IUUC-Ttr-128465	Tursiops truncatus	33.27	7.00e-75	273.00
IUUC-Uma-129645	Ustilago maydis	33.23	3.00e-78	284.00
IUUC-Vda-129989	Verticillium dahliae	41.10	8.00e-102	362.00
IUUC-Vpa-130529	Vicugna pacos	33.39	5.00e-77	280.00
IUUC-Vvi-131059	Vitis vinifera	31.96	3.00e-75	273.00
IUUC-Xtr-132002	Xenopus tropicalis	35.62	1.00e-86	311.00
IUUC-Xma-133930	Xiphophorus maculatus	33.93	2.00e-85	308.00
IUUC-Yli-134505	Yarrowia lipolytica	36.49	8.00e-84	302.00
IUUC-Zma-135895	Zea mays	32.85	5.00e-74	270.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence