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Tag Content
iUUCD ID IUUC-Bta-013304
Ensembl Protein ID ENSBTAP00000019973.3
UniProt Accession Q5E951; Q3ZCC1; TBCB_BOVIN
Genbank Protein ID AAX09086.1; AAI02572.1
Protein Name Tubulin-folding cofactor B; Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; Tubulin-specific chaperone B
Genbank Nucleotide ID BT021069; BC102571
Gene Name TBCB; CKAP1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000015004.3 ENSBTAT00000019973.3 ENSBTAP00000019973.3
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 43.24 7.00e-45 177.00 IUUC-Cel-018176
ULD/UDP/UBQ/UBQ_Other 34.04 5.00e-27 115.00 IUUC-Spo-108310
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Bos taurus
Functional Description
(View)

Functional Description


     Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
 Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
Protein Sequence
(Fasta)
MEVTGLSAPT VNVFISSSLN SFRSQKRYSR SLTVAEFKCK LQLVVGSPAS CMELELYGPD 60
DKFCCKLDQD DALLGSYPVD DGCRIHVIDH SGARLGEYED ISKVEKYEIS QEAYEQRQDS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-013304|ULD,UBQ_Other|Bos taurus
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Nucleotide Sequence
(Fasta)
GCGGCTGTCC GGGCTGAGGG CCGCCACAGG GCGCGGCGAG ATGGAGGTGA CGGGGTTGTC 60
GGCGCCCACA GTGAACGTGT TCATCAGCAG CTCTCTCAAC AGCTTTCGCT CCCAGAAGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-013304|ULD,UBQ_Other|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0143--Chaperone
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0493--Microtubule
KW-0524--Neurogenesis
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0832--Ubl conjugation
Interpro

IPR000938--CAP-Gly_domain
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
PROSITE

PS00845--CAP_GLY_1
PS50245--CAP_GLY_2
Pfam

PF01302--CAP_GLY
PF14560--Ubiquitin_2
SMART

SM01052--CAP_GLY
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005874--C:microtubule
GO:0030154--P:cell differentiation
GO:0007399--P:nervous system development
GO:0007023--P:post-chaperonin tubulin folding pathway
KEGG bta:530447
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000863 Aegilops tauschii 39.51 2.00e-25 108.00
IUUC-Aml-002358 Ailuropoda melanoleuca 88.35 3.00e-121 427.00
IUUC-Atr-003043 Amborella trichopoda 39.30 5.00e-35 140.00
IUUC-Aca-004737 Anolis carolinensis 70.87 6.00e-81 293.00
IUUC-Aly-005916 Arabidopsis lyrata 38.89 2.00e-35 142.00
IUUC-Ath-007038 Arabidopsis thaliana 40.17 5.00e-36 144.00
IUUC-Ago-007723 Ashbya gossypii 38.76 1.00e-14 73.60
IUUC-Acl-008216 Aspergillus clavatus 36.55 6.00e-33 134.00
IUUC-Afl-008534 Aspergillus flavus 34.80 5.00e-31 127.00
IUUC-Afu-008927 Aspergillus fumigatus 36.64 3.00e-32 131.00
IUUC-Ani-009283 Aspergillus nidulans 37.94 2.00e-32 132.00
IUUC-Ang-009564 Aspergillus niger 36.40 2.00e-31 129.00
IUUC-Aor-010034 Aspergillus oryzae 34.80 5.00e-31 127.00
IUUC-Ate-010424 Aspergillus terreus 37.25 7.00e-32 130.00
IUUC-Ame-011741 Astyanax mexicanus 61.48 1.00e-79 289.00
IUUC-Bgr-011988 Blumeria graminis 37.25 2.00e-32 132.00
IUUC-Bci-013694 Botrytis cinerea 41.20 1.00e-36 145.00
IUUC-Bdi-014585 Brachypodium distachyon 38.33 4.00e-32 131.00
IUUC-Bol-015891 Brassica oleracea 39.82 2.00e-35 142.00
IUUC-Bra-017389 Brassica rapa 40.27 5.00e-36 144.00
IUUC-Cel-018176 Caenorhabditis elegans 43.69 2.00e-46 178.00
IUUC-Cja-019754 Callithrix jacchus 87.70 8.00e-117 412.00
IUUC-Cfa-020813 Canis familiaris 91.39 1.00e-123 435.00
IUUC-Cpo-021932 Cavia porcellus 88.93 9.00e-122 429.00
IUUC-Cre-022753 Chlamydomonas reinhardtii 37.22 1.00e-29 123.00
IUUC-Csa-023261 Chlorocebus sabaeus 87.30 6.00e-116 409.00
IUUC-Cin-025428 Ciona intestinalis 48.99 7.00e-61 226.00
IUUC-Csv-025811 Ciona savignyi 50.00 1.00e-56 212.00
IUUC-Cgl-026504 Colletotrichum gloeosporioides 36.36 7.00e-31 127.00
IUUC-Cne-026867 Cryptococcus neoformans 36.89 5.00e-30 124.00
IUUC-Cme-027227 Cyanidioschyzon merolae 37.69 2.00e-12 65.90
IUUC-Dre-028683 Danio rerio 64.46 1.00e-80 292.00
IUUC-Dno-029817 Dasypus novemcinctus 89.75 3.00e-119 421.00
IUUC-Dor-030906 Dipodomys ordii 85.25 7.00e-110 389.00
IUUC-Dse-031240 Dothistroma septosporum 37.56 7.00e-32 130.00
IUUC-Dme-031894 Drosophila melanogaster 44.49 3.00e-48 184.00
IUUC-Eca-034216 Equus caballus 89.75 5.00e-126 443.00
IUUC-Eeu-035155 Erinaceus europaeus 85.44 3.00e-98 350.00
IUUC-Fca-035461 Felis catus 89.75 3.00e-122 430.00
IUUC-Fal-037458 Ficedula albicollis 53.52 7.00e-14 72.40
IUUC-Fox-037822 Fusarium oxysporum 36.89 1.00e-32 133.00
IUUC-Fso-038149 Fusarium solani 35.84 9.00e-33 133.00
IUUC-Gmo-038810 Gadus morhua 55.37 2.00e-69 255.00
IUUC-Ggr-039751 Gaeumannomyces graminis 28.69 1.00e-19 89.70
IUUC-Gga-040168 Gallus gallus 54.55 9.00e-14 71.20
IUUC-Gac-041700 Gasterosteus aculeatus 60.08 2.00e-78 285.00
IUUC-Gma-044336 Glycine max 38.72 2.00e-35 142.00
IUUC-Ggo-044442 Gorilla gorilla 87.44 8.00e-96 342.00
IUUC-Hsa-046441 Homo sapiens 87.70 2.00e-116 411.00
IUUC-Hvu-047163 Hordeum vulgare 38.18 5.00e-28 117.00
IUUC-Itr-048652 Ictidomys tridecemlineatus 87.30 6.00e-122 429.00
IUUC-Kpa-049126 Komagataella pastoris 32.27 7.00e-31 127.00
IUUC-Lch-050256 Latimeria chalumnae 66.39 9.00e-93 332.00
IUUC-Lpe-051676 Leersia perrieri 40.26 8.00e-31 126.00
IUUC-Loc-051891 Lepisosteus oculatus 67.56 5.00e-87 313.00
IUUC-Lma-052977 Leptosphaeria maculans 37.30 5.00e-33 134.00
IUUC-Laf-053381 Loxodonta africana 86.07 4.00e-116 410.00
IUUC-Mcc-055434 Macaca mulatta 87.30 6.00e-116 409.00
IUUC-Meu-056675 Macropus eugenii 68.72 4.00e-86 310.00
IUUC-Mor-056937 Magnaporthe oryzae 39.37 5.00e-29 120.00
IUUC-Mpo-057404 Magnaporthe poae 35.84 5.00e-28 117.00
IUUC-Mtr-058357 Medicago truncatula 41.18 1.00e-34 139.00
IUUC-Mla-059125 Melampsora laricipopulina 42.34 2.00e-41 162.00
IUUC-Mga-059996 Meleagris gallopavo 55.56 9.00e-14 71.20
IUUC-Mvi-060558 Microbotryum violaceum 33.98 2.00e-34 139.00
IUUC-Mmr-061473 Microcebus murinus 89.34 5.00e-121 426.00
IUUC-Mdo-061846 Monodelphis domestica 79.84 6.00e-107 379.00
IUUC-Mmu-063321 Mus musculus 85.66 1.00e-114 405.00
IUUC-Mac-065590 Musa acuminata 38.94 8.00e-36 143.00
IUUC-Mpu-066149 Mustela putorius furo 90.98 3.00e-124 437.00
IUUC-Mlu-067002 Myotis lucifugus 89.75 7.00e-123 432.00
IUUC-Nfi-068351 Neosartorya fischeri 35.47 1.00e-29 123.00
IUUC-Ncr-068854 Neurospora crassa 34.33 6.00e-29 120.00
IUUC-Nle-069008 Nomascus leucogenys 83.20 1.00e-108 385.00
IUUC-Opr-070608 Ochotona princeps 81.56 9.00e-111 392.00
IUUC-Ont-071543 Oreochromis niloticus 61.16 3.00e-85 307.00
IUUC-Oan-073488 Ornithorhynchus anatinus 75.68 2.00e-72 264.00
IUUC-Ocu-073951 Oryctolagus cuniculus 87.70 3.00e-119 420.00
IUUC-Oba-075033 Oryza barthii 39.13 1.00e-34 139.00
IUUC-Obr-076908 Oryza brachyantha 40.43 6.00e-37 147.00
IUUC-Ogl-077907 Oryza glaberrima 40.43 6.00e-37 147.00
IUUC-Ogu-078871 Oryza glumaepatula 39.13 1.00e-34 139.00
IUUC-Oin-080206 Oryza indica 40.43 5.00e-37 147.00
IUUC-Olo-080756 Oryza longistaminata 51.72 6.00e-20 89.00
IUUC-Ome-081319 Oryza meridionalis 51.72 6.00e-20 89.00
IUUC-Oni-082550 Oryza nivara 39.13 6.00e-34 137.00
IUUC-Opu-083656 Oryza punctata 40.48 1.00e-32 133.00
IUUC-Oru-084482 Oryza rufipogon 39.13 1.00e-34 139.00
IUUC-Osa-085952 Oryza sativa 40.43 6.00e-37 147.00
IUUC-Ola-087407 Oryzias latipes 58.13 4.00e-77 280.00
IUUC-Olu-087778 Ostreococcus lucimarinus 36.18 6.00e-34 137.00
IUUC-Oga-088233 Otolemur garnettii 88.52 3.00e-117 413.00
IUUC-Oar-089581 Ovis aries 97.54 2.00e-134 471.00
IUUC-Ptr-091547 Pan troglodytes 87.70 2.00e-116 411.00
IUUC-Pan-092061 Papio anubis 87.30 6.00e-116 409.00
IUUC-Psi-093234 Pelodiscus sinensis 73.44 5.00e-76 276.00
IUUC-Pma-094359 Petromyzon marinus 57.99 7.00e-72 263.00
IUUC-Pno-094999 Phaeosphaeria nodorum 39.02 6.00e-36 144.00
IUUC-Ppa-095653 Physcomitrella patens 34.21 8.00e-29 120.00
IUUC-Pfo-096130 Poecilia formosa 59.67 1.00e-82 298.00
IUUC-Pop-099133 Populus trichocarpa 38.50 2.00e-35 142.00
IUUC-Pca-100784 Procavia capensis 73.36 8.00e-92 329.00
IUUC-Ppe-101764 Prunus persica 42.04 3.00e-37 148.00
IUUC-Pva-102882 Pteropus vampyrus 89.34 2.00e-122 431.00
IUUC-Pgr-103337 Puccinia graminis 42.15 2.00e-44 172.00
IUUC-Ptt-103764 Puccinia triticina 35.22 1.00e-31 130.00
IUUC-Pte-104265 Pyrenophora teres 37.50 2.00e-30 125.00
IUUC-Pyt-104528 Pyrenophora triticirepentis 54.17 3.00e-18 85.50
IUUC-Rno-104851 Rattus norvegicus 85.66 8.00e-112 395.00
IUUC-Sce-106183 Saccharomyces cerevisiae 29.46 1.00e-12 66.60
IUUC-Sha-106933 Sarcophilus harrisii 43.06 1.00e-06 47.80
IUUC-Sja-107978 Schizosaccharomyces japonicus 36.73 3.00e-31 128.00
IUUC-Spo-108310 Schizosaccharomyces pombe 35.32 8.00e-30 123.00
IUUC-Ssl-108484 Sclerotinia sclerotiorum 34.62 1.00e-22 99.40
IUUC-Sit-110751 Setaria italica 38.26 8.00e-31 127.00
IUUC-Sly-111811 Solanum lycopersicum 39.39 4.00e-36 144.00
IUUC-Stu-111984 Solanum tuberosum 40.26 2.00e-37 148.00
IUUC-Sar-113382 Sorex araneus 82.97 7.00e-81 292.00
IUUC-Sbi-113807 Sorghum bicolor 37.95 9.00e-27 113.00
IUUC-Sre-115083 Sporisorium reilianum 32.14 4.00e-31 127.00
IUUC-Ssc-116306 Sus scrofa 93.44 1.00e-126 444.00
IUUC-Tru-117880 Takifugu rubripes 61.16 1.00e-85 308.00
IUUC-Tni-119713 Tetraodon nigroviridis 61.30 5.00e-80 290.00
IUUC-Tca-121819 Theobroma cacao 41.59 1.00e-37 149.00
IUUC-Tre-122044 Trichoderma reesei 38.84 2.00e-33 135.00
IUUC-Tvi-122273 Trichoderma virens 37.50 1.00e-32 132.00
IUUC-Tae-123023 Triticum aestivum 39.55 6.00e-28 117.00
IUUC-Tur-126446 Triticum urartu 41.03 1.00e-22 99.40
IUUC-Tme-127153 Tuber melanosporum 35.80 3.00e-36 144.00
IUUC-Tbe-127834 Tupaia belangeri 85.42 3.00e-58 216.00
IUUC-Ttr-128351 Tursiops truncatus 73.77 8.00e-99 352.00
IUUC-Uma-129608 Ustilago maydis 32.03 4.00e-28 118.00
IUUC-Vda-129806 Verticillium dahliae 34.17 3.00e-30 125.00
IUUC-Vpa-130329 Vicugna pacos 48.15 4.00e-14 73.20
IUUC-Vvi-131178 Vitis vinifera 39.56 3.00e-34 138.00
IUUC-Xtr-132139 Xenopus tropicalis 71.18 4.00e-95 340.00
IUUC-Xma-134015 Xiphophorus maculatus 60.49 3.00e-83 301.00
IUUC-Yli-134439 Yarrowia lipolytica 37.80 1.00e-33 135.00
IUUC-Zma-135720 Zea mays 37.50 1.00e-25 109.00
Created Date 25-Jun-2017

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