iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022345

Ensembl Protein ID

ENSCPOP00000004894.2

UniProt Accession

H0V5G4; H0V5G4_CAVPO

Genbank Protein ID

ENSCPOP00000004894

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02031297

Gene Name

EP300

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000005438.3	ENSCPOT00000005496.2	ENSCPOP00000004894.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	91.08	0.00e+00	3332.00	IUUC-Hsa-046884

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

DFGSLFDLEH DLPDELINST ELGLTNGGDI NQLQTNLGMA QDAASKHKQL SELLRSGSSP 60
NLNMGVGGPG QVMASQAQQN SPGLGLINSM VKSPMAQAGL TSPNMGMGTS GPNQGPTQST 120

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Nucleotide Sequence
(Fasta)

GATTTTGGCT CTTTGTTTGA CCTGGAGCAT GACTTACCAG ATGAATTAAT CAACTCTACA 60
GAATTGGGAC TAACCAACGG TGGTGATATT AATCAGCTTC AGACAAATCT TGGCATGGCA 120

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Sequence Source

Ensembl

Keyword

KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR031162--CBP_P300_HAT
IPR013178--Histone_AcTrfase_Rtt109/CBP
IPR003101--KIX_dom
IPR009110--Nuc_rcpt_coact
IPR014744--Nuc_rcpt_coact_CREBbp
IPR010303--RING_CBP-p300
IPR000197--Znf_TAZ
IPR000433--Znf_ZZ

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51727--CBP_P300_HAT
PS50952--KIX
PS50134--ZF_TAZ
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00439--Bromodomain
PF09030--Creb_binding
PF06001--DUF902
PF08214--HAT_KAT11
PF02172--KIX
PF02135--zf-TAZ
PF00569--ZZ

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM01250--KAT11
SM00551--ZnF_TAZ
SM00291--ZnF_ZZ

Gene Ontology

GO:0005829--C:cytosol
GO:0000123--C:histone acetyltransferase complex
GO:0005667--C:transcription factor complex
GO:0031490--F:chromatin DNA binding
GO:0003684--F:damaged DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0097157--F:pre-mRNA intronic binding
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0009887--P:animal organ morphogenesis
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0007623--P:circadian rhythm
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0043969--P:histone H2B acetylation
GO:0043967--P:histone H4 acetylation
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0030324--P:lung development
GO:0010742--P:macrophage derived foam cell differentiation
GO:0035855--P:megakaryocyte development
GO:0018076--P:N-terminal peptidyl-lysine acetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030220--P:platelet formation
GO:0043923--P:positive regulation by host of viral transcription
GO:0032092--P:positive regulation of protein binding
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0006990--P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0050821--P:protein stabilization
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0090043--P:regulation of tubulin deacetylation
GO:0043627--P:response to estrogen
GO:0001666--P:response to hypoxia
GO:0007519--P:skeletal muscle tissue development
GO:0001756--P:somitogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002027	Ailuropoda melanoleuca	92.30	0.00e+00	1879.00
IUUC-Aca-005040	Anolis carolinensis	79.34	0.00e+00	1794.00
IUUC-Ame-011395	Astyanax mexicanus	85.06	0.00e+00	1457.00
IUUC-Bta-012649	Bos taurus	90.28	0.00e+00	1939.00
IUUC-Cel-018691	Caenorhabditis elegans	50.00	0.00e+00	835.00
IUUC-Cja-019649	Callithrix jacchus	91.62	0.00e+00	2067.00
IUUC-Cfa-020764	Canis familiaris	92.57	0.00e+00	1774.00
IUUC-Cre-022852	Chlamydomonas reinhardtii	35.09	1.00e-64	241.00
IUUC-Csa-023866	Chlorocebus sabaeus	91.84	0.00e+00	2016.00
IUUC-Cho-024951	Choloepus hoffmanni	93.60	0.00e+00	1210.00
IUUC-Dre-028500	Danio rerio	65.50	0.00e+00	1837.00
IUUC-Dor-030287	Dipodomys ordii	92.68	0.00e+00	1183.00
IUUC-Dme-031716	Drosophila melanogaster	72.52	0.00e+00	770.00
IUUC-Ete-032979	Echinops telfairi	86.96	0.00e+00	1801.00
IUUC-Eca-034048	Equus caballus	92.46	0.00e+00	1867.00
IUUC-Fca-035891	Felis catus	90.51	0.00e+00	1977.00
IUUC-Fal-037585	Ficedula albicollis	82.44	0.00e+00	1855.00
IUUC-Gmo-039348	Gadus morhua	85.16	0.00e+00	1434.00
IUUC-Gga-040916	Gallus gallus	82.22	0.00e+00	1872.00
IUUC-Gac-041642	Gasterosteus aculeatus	87.37	0.00e+00	1408.00
IUUC-Ggo-045189	Gorilla gorilla	91.56	0.00e+00	2013.00
IUUC-Hsa-046884	Homo sapiens	91.69	0.00e+00	2014.00
IUUC-Itr-048564	Ictidomys tridecemlineatus	92.48	0.00e+00	1825.00
IUUC-Laf-054423	Loxodonta africana	90.98	0.00e+00	2069.00
IUUC-Mcc-054847	Macaca mulatta	91.90	0.00e+00	2023.00
IUUC-Meu-056217	Macropus eugenii	80.93	0.00e+00	1879.00
IUUC-Mga-059250	Meleagris gallopavo	79.68	0.00e+00	1882.00
IUUC-Mmr-061496	Microcebus murinus	91.11	0.00e+00	2016.00
IUUC-Mdo-062478	Monodelphis domestica	84.49	0.00e+00	1920.00
IUUC-Mmu-063456	Mus musculus	92.14	0.00e+00	1859.00
IUUC-Mac-064767	Musa acuminata	39.35	1.00e-74	275.00
IUUC-Mpu-065963	Mustela putorius furo	91.03	0.00e+00	1840.00
IUUC-Mlu-067185	Myotis lucifugus	91.44	0.00e+00	1857.00
IUUC-Ncr-068795	Neurospora crassa	37.97	1.00e-13	71.20
IUUC-Nle-069907	Nomascus leucogenys	93.20	0.00e+00	1860.00
IUUC-Opr-070324	Ochotona princeps	83.77	0.00e+00	1958.00
IUUC-Ont-072211	Oreochromis niloticus	79.30	0.00e+00	1446.00
IUUC-Oan-073723	Ornithorhynchus anatinus	86.82	0.00e+00	1835.00
IUUC-Ocu-074707	Oryctolagus cuniculus	90.28	0.00e+00	1934.00
IUUC-Osa-085860	Oryza sativa	42.26	5.00e-62	233.00
IUUC-Olu-087701	Ostreococcus lucimarinus	34.95	1.00e-61	231.00
IUUC-Oga-088700	Otolemur garnettii	90.39	0.00e+00	3259.00
IUUC-Oar-089787	Ovis aries	88.15	0.00e+00	1920.00
IUUC-Ptr-091620	Pan troglodytes	91.95	0.00e+00	2016.00
IUUC-Pan-092166	Papio anubis	92.07	0.00e+00	2044.00
IUUC-Psi-093992	Pelodiscus sinensis	82.69	0.00e+00	1939.00
IUUC-Pma-094328	Petromyzon marinus	84.65	0.00e+00	979.00
IUUC-Ppa-095569	Physcomitrella patens	37.97	2.00e-70	261.00
IUUC-Pfo-097342	Poecilia formosa	84.32	0.00e+00	1370.00
IUUC-Pab-098235	Pongo abelii	91.90	0.00e+00	1997.00
IUUC-Pop-098947	Populus trichocarpa	39.75	2.00e-72	268.00
IUUC-Pca-100780	Procavia capensis	86.82	0.00e+00	1435.00
IUUC-Ppe-101498	Prunus persica	37.47	5.00e-66	246.00
IUUC-Pva-103071	Pteropus vampyrus	90.36	0.00e+00	2079.00
IUUC-Sha-106736	Sarcophilus harrisii	82.74	0.00e+00	2727.00
IUUC-Sar-113162	Sorex araneus	89.94	0.00e+00	833.00
IUUC-Ssc-116077	Sus scrofa	91.79	0.00e+00	1985.00
IUUC-Tgu-116872	Taeniopygia guttata	81.47	0.00e+00	1871.00
IUUC-Tru-118047	Takifugu rubripes	64.38	0.00e+00	1760.00
IUUC-Tsy-119451	Tarsius syrichta	81.85	0.00e+00	1278.00
IUUC-Tca-121835	Theobroma cacao	39.65	9.00e-73	269.00
IUUC-Tbe-127772	Tupaia belangeri	82.18	0.00e+00	1325.00
IUUC-Ttr-128325	Tursiops truncatus	94.10	0.00e+00	1445.00
IUUC-Vpa-130766	Vicugna pacos	87.73	0.00e+00	1211.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence