iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073562

UUCD1 version

UUC-OrA-00106

Ensembl Protein ID

ENSOANP00000015384.4

UniProt Accession

F6S036; F6S036_ORNAN

Protein Name

Uncharacterized protein

Gene Name

TBL1Y

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000009691.4	ENSOANT00000015387.4	ENSOANP00000015384.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-54	177.6	454	492
UBD/Beta-Prp	2.40e-64	217.6	333	526

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g+l++s
   Q: 454  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGTLVHS 492
           9**********999*******************999876 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp....... 104
           + +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h+++++++++sp       
   Q: 333  TTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPtgpgtsn 421
           45667777777777777777777777777777777777777777777777777777777777777777777777777777776666555 PP
   S: 105  ..sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsn 191
             s+  l+s+s d+t+r+wd+e g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ +  + ++  
   Q: 422  pnSNIMLASASFDSTVRLWDVERGVCIH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRG--TGGIFEVCWNAR 507
           5333567777777777777777777777.7777777777777777777777777777777777777777777777..777777777777 PP
   S: 192  gkelvsgsldgtvklwdlq 210
           g  + + + dg+v + dl+
   Q: 508  GDKVGASASDGSVCVLDLR 526
           7777777777777777765 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MSITSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GTLVPPAALI SILQKGLQYV 60
EAEISINEDG TVFDGRPIES LSLIDAVMPD VVQTRQQAFR EKLAQQQASA AAAAAAATAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGAGTAA AAAGAAATGA GGGTGTTTTT GTTGGGTTTT TTTTTTTCTC TCTACCAGCT 60
CAGGTCGGTG TGCTTGGCTT TTTTTTTTTT CCCCCTAGGA GGTCACTGAC TGTCTCTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0016575--P:histone deacetylation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

KEGG

oaa:100084465

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000916	Aegilops tauschii	60.00	9.00e-55	204.00
IUUC-Aml-001450	Ailuropoda melanoleuca	92.79	0.00e+00	996.00
IUUC-Atr-002514	Amborella trichopoda	64.29	5.00e-143	500.00
IUUC-Apl-003232	Anas platyrhynchos	96.02	0.00e+00	1006.00
IUUC-Aca-005035	Anolis carolinensis	95.83	0.00e+00	1010.00
IUUC-Aly-005622	Arabidopsis lyrata	55.84	1.00e-119	422.00
IUUC-Ath-007137	Arabidopsis thaliana	59.23	5.00e-121	427.00
IUUC-Ago-007869	Ashbya gossypii	27.68	7.00e-33	134.00
IUUC-Ame-011601	Astyanax mexicanus	84.06	0.00e+00	868.00
IUUC-Bgr-012011	Blumeria graminis	29.92	2.00e-32	133.00
IUUC-Bta-013202	Bos taurus	96.78	0.00e+00	1010.00
IUUC-Bdi-014315	Brachypodium distachyon	61.19	8.00e-135	473.00
IUUC-Bol-016277	Brassica oleracea	56.96	4.00e-126	444.00
IUUC-Bra-016944	Brassica rapa	57.33	1.00e-125	442.00
IUUC-Cja-019281	Callithrix jacchus	91.65	0.00e+00	979.00
IUUC-Cfa-020929	Canis familiaris	97.15	0.00e+00	1007.00
IUUC-Cpo-022080	Cavia porcellus	83.36	0.00e+00	850.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.43	5.00e-132	463.00
IUUC-Csa-023943	Chlorocebus sabaeus	92.03	0.00e+00	980.00
IUUC-Cin-025704	Ciona intestinalis	72.22	0.00e+00	798.00
IUUC-Csv-026257	Ciona savignyi	69.76	0.00e+00	764.00
IUUC-Cne-026946	Cryptococcus neoformans	38.01	7.00e-31	128.00
IUUC-Cme-027258	Cyanidioschyzon merolae	39.36	7.00e-106	377.00
IUUC-Dre-028075	Danio rerio	85.01	0.00e+00	874.00
IUUC-Dno-028926	Dasypus novemcinctus	95.83	0.00e+00	996.00
IUUC-Dor-030732	Dipodomys ordii	91.21	0.00e+00	684.00
IUUC-Dse-031538	Dothistroma septosporum	30.30	2.00e-33	135.00
IUUC-Dme-031939	Drosophila melanogaster	82.02	4.00e-176	610.00
IUUC-Ete-032822	Echinops telfairi	83.68	0.00e+00	844.00
IUUC-Eca-033897	Equus caballus	97.34	0.00e+00	1010.00
IUUC-Eeu-034952	Erinaceus europaeus	78.82	0.00e+00	757.00
IUUC-Fca-036462	Felis catus	97.72	0.00e+00	1011.00
IUUC-Fal-037388	Ficedula albicollis	96.96	0.00e+00	1013.00
IUUC-Gmo-038870	Gadus morhua	84.09	0.00e+00	885.00
IUUC-Gga-040671	Gallus gallus	96.77	0.00e+00	1013.00
IUUC-Gac-041851	Gasterosteus aculeatus	90.13	0.00e+00	936.00
IUUC-Gma-044208	Glycine max	48.95	4.00e-152	530.00
IUUC-Ggo-045373	Gorilla gorilla	94.12	0.00e+00	993.00
IUUC-Hsa-045841	Homo sapiens	94.12	0.00e+00	988.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	99.19	0.00e+00	780.00
IUUC-Kpa-049338	Komagataella pastoris	27.67	2.00e-31	129.00
IUUC-Lch-050535	Latimeria chalumnae	91.65	0.00e+00	981.00
IUUC-Lpe-051084	Leersia perrieri	62.09	6.00e-135	473.00
IUUC-Loc-052030	Lepisosteus oculatus	87.69	0.00e+00	904.00
IUUC-Laf-054071	Loxodonta africana	96.41	0.00e+00	1006.00
IUUC-Mcc-055233	Macaca mulatta	92.69	0.00e+00	963.00
IUUC-Meu-056563	Macropus eugenii	91.60	4.00e-129	453.00
IUUC-Mtr-058624	Medicago truncatula	60.16	5.00e-127	447.00
IUUC-Mga-059895	Meleagris gallopavo	97.34	0.00e+00	1013.00
IUUC-Mvi-060557	Microbotryum violaceum	36.51	1.00e-69	257.00
IUUC-Mmr-061286	Microcebus murinus	96.23	0.00e+00	1013.00
IUUC-Mdo-062078	Monodelphis domestica	88.07	0.00e+00	886.00
IUUC-Mmu-063447	Mus musculus	97.34	0.00e+00	1011.00
IUUC-Mac-065508	Musa acuminata	61.42	5.00e-92	330.00
IUUC-Mpu-066741	Mustela putorius furo	87.50	0.00e+00	884.00
IUUC-Mlu-068152	Myotis lucifugus	88.26	0.00e+00	880.00
IUUC-Nle-069151	Nomascus leucogenys	92.98	0.00e+00	982.00
IUUC-Opr-070277	Ochotona princeps	78.69	0.00e+00	747.00
IUUC-Ont-072252	Oreochromis niloticus	89.56	0.00e+00	957.00
IUUC-Ocu-074280	Oryctolagus cuniculus	86.53	0.00e+00	889.00
IUUC-Oba-075618	Oryza barthii	58.18	1.00e-123	436.00
IUUC-Obr-076718	Oryza brachyantha	61.66	4.00e-136	477.00
IUUC-Ogl-077302	Oryza glaberrima	50.18	3.00e-153	534.00
IUUC-Ogu-078718	Oryza glumaepatula	50.18	2.00e-153	535.00
IUUC-Olo-080427	Oryza longistaminata	62.46	3.00e-130	458.00
IUUC-Ome-081696	Oryza meridionalis	49.11	7.00e-148	516.00
IUUC-Oni-082137	Oryza nivara	50.18	2.00e-153	535.00
IUUC-Opu-083505	Oryza punctata	47.93	9.00e-143	499.00
IUUC-Oru-085276	Oryza rufipogon	50.18	1.00e-153	535.00
IUUC-Osa-085791	Oryza sativa	50.18	2.00e-153	535.00
IUUC-Ola-087365	Oryzias latipes	84.63	0.00e+00	900.00
IUUC-Olu-087589	Ostreococcus lucimarinus	51.73	9.00e-156	542.00
IUUC-Oga-088357	Otolemur garnettii	83.52	0.00e+00	832.00
IUUC-Oar-089506	Ovis aries	94.50	0.00e+00	1007.00
IUUC-Ptr-090793	Pan troglodytes	92.41	0.00e+00	951.00
IUUC-Pan-091909	Papio anubis	93.02	0.00e+00	985.00
IUUC-Psi-093358	Pelodiscus sinensis	91.81	0.00e+00	964.00
IUUC-Ppa-095868	Physcomitrella patens	66.02	1.00e-139	489.00
IUUC-Pfo-097214	Poecilia formosa	88.43	0.00e+00	925.00
IUUC-Pab-098317	Pongo abelii	93.62	0.00e+00	966.00
IUUC-Pop-098989	Populus trichocarpa	57.89	1.00e-128	452.00
IUUC-Pca-100256	Procavia capensis	87.19	0.00e+00	872.00
IUUC-Ppe-101572	Prunus persica	63.97	2.00e-128	452.00
IUUC-Pva-102616	Pteropus vampyrus	85.19	0.00e+00	875.00
IUUC-Rno-105857	Rattus norvegicus	97.34	0.00e+00	1011.00
IUUC-Sce-106132	Saccharomyces cerevisiae	23.96	2.00e-39	156.00
IUUC-Sha-107326	Sarcophilus harrisii	95.45	0.00e+00	1027.00
IUUC-Smo-109205	Selaginella moellendorffii	61.54	3.00e-135	474.00
IUUC-Sit-110710	Setaria italica	62.16	2.00e-140	492.00
IUUC-Sly-111042	Solanum lycopersicum	50.19	7.00e-150	523.00
IUUC-Stu-112786	Solanum tuberosum	48.41	1.00e-141	495.00
IUUC-Sar-112971	Sorex araneus	80.92	0.00e+00	811.00
IUUC-Sbi-114420	Sorghum bicolor	61.66	8.00e-141	493.00
IUUC-Sre-115175	Sporisorium reilianum	40.07	2.00e-56	214.00
IUUC-Ssc-115646	Sus scrofa	97.54	0.00e+00	1016.00
IUUC-Tgu-116898	Taeniopygia guttata	96.20	0.00e+00	1007.00
IUUC-Tru-117862	Takifugu rubripes	89.75	0.00e+00	947.00
IUUC-Tsy-119424	Tarsius syrichta	73.13	0.00e+00	670.00
IUUC-Tni-119656	Tetraodon nigroviridis	90.51	0.00e+00	947.00
IUUC-Tca-121739	Theobroma cacao	54.29	9.00e-125	439.00
IUUC-Tae-125368	Triticum aestivum	59.38	5.00e-135	473.00
IUUC-Tme-127126	Tuber melanosporum	36.99	7.00e-56	210.00
IUUC-Tbe-127665	Tupaia belangeri	74.57	0.00e+00	763.00
IUUC-Ttr-128826	Tursiops truncatus	96.49	0.00e+00	925.00
IUUC-Uma-129469	Ustilago maydis	43.53	2.00e-58	220.00
IUUC-Vpa-130768	Vicugna pacos	87.19	0.00e+00	870.00
IUUC-Vvi-131193	Vitis vinifera	57.14	8.00e-130	456.00
IUUC-Xtr-132842	Xenopus tropicalis	86.36	0.00e+00	849.00
IUUC-Xma-133591	Xiphophorus maculatus	88.24	0.00e+00	924.00
IUUC-Yli-134648	Yarrowia lipolytica	29.62	5.00e-42	165.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence