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Tag Content
UUCD2 ID IUUC-Cpo-022260
UUCD1 version UUC-CaP-00392
Ensembl Protein ID ENSCPOP00000007922.2
UniProt Accession H0VD76; H0VD76_CAVPO
Genbank Protein ID ENSCPOP00000007922
Protein Name Ribosome biogenesis protein WDR12; WD repeat-containing protein 12
Genbank Nucleotide ID AAKN02019450
Gene Name WDR12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000008824.3 ENSCPOT00000008903.2 ENSCPOP00000007922.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.00e-43 143.9 255 290
UBD/Beta-Prp 1.00e-46 159.5 246 412
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gHt+ ++++ +sd   ++s+s+D+ti+vWD+ +g l
   Q: 255  GHTEAISSVLWSDaEEICSASWDHTIRVWDVESGSL 290
           8**********999*****************99976 PP
   

   UBD/Beta-Prp
   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..ktg 169
           t+++++tl+gh++ + s+ +s   + + s+s+d tirvwd+e+g+  + tl+g++ v nc++++p ++ l+sGs+Dr +rlWd   k g
   Q: 246  TRTPIVTLSGHTEAISSVLWSD-AEEICSASWDHTIRVWDVESGSLKS-TLTGNK-VFNCISYSPLCKRLASGSTDRHIRLWDPrtKDG 331
           67899****************9.99**********************9.***987.99**************************54456 PP
   S: 170  kllrtl.tgghtdsvyslsfdsng.kelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +l+    t+ ht+ v+s++++++  ++l+sgsld+ vklwd +  +  ++ l +h+d v+sv+ + ++ +l+sg++D+ ++ +
   Q: 332  SLVSLSlTS-HTGWVTSVKWSPTHeQQLISGSLDNIVKLWDTRsCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGADNKLYSY 412
           666644366.************9889*****************54566****************9.999********998765 PP
   
Organism Cavia porcellus
Functional Description
(View)

Functional Description


     Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
 Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Protein Sequence
(Fasta)
MAQLQTRFFT DNKKYAVDDV PFSIPASSEI ADLSNIINKL LEAKNEFHKY VEFDFLIKGQ 60
FLRMPLAKHM EVENISSEEV VELEYVEKYT APQPEQCMFH DDWVSAVKGA EEWILTGSYD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cpo-022260|E3,WD_repeat;UBD,Beta-Prp|Cavia porcellus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCTCAGC TCCAGACACG CTTCTTCACG GACAACAAGA AGTAAGTGAG CGGCCCGGCC 60
TTCGCACCTC TCTCCCCTCC CTGGGTCTCA CCAGGGGACC CCCCCTCCGC GTTGTGGCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cpo-022260|E3,WD_repeat;UBD,Beta-Prp|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0008283--P:cell proliferation
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0007219--P:Notch signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000532 Aegilops tauschii 34.20 8.00e-58 217.00
IUUC-Aml-001997 Ailuropoda melanoleuca 96.10 0.00e+00 743.00
IUUC-Atr-002544 Amborella trichopoda 33.57 9.00e-56 211.00
IUUC-Apl-003981 Anas platyrhynchos 86.44 0.00e+00 643.00
IUUC-Aca-004370 Anolis carolinensis 84.94 0.00e+00 704.00
IUUC-Aly-006455 Arabidopsis lyrata 35.71 2.00e-59 222.00
IUUC-Ath-006669 Arabidopsis thaliana 34.89 5.00e-55 208.00
IUUC-Ago-007864 Ashbya gossypii 30.16 4.00e-36 145.00
IUUC-Acl-008177 Aspergillus clavatus 28.22 2.00e-35 143.00
IUUC-Afl-008617 Aspergillus flavus 28.97 2.00e-34 140.00
IUUC-Afu-008752 Aspergillus fumigatus 28.05 7.00e-32 131.00
IUUC-Ani-009136 Aspergillus nidulans 29.74 1.00e-34 140.00
IUUC-Ang-009701 Aspergillus niger 27.69 2.00e-31 130.00
IUUC-Aor-009884 Aspergillus oryzae 29.23 3.00e-34 139.00
IUUC-Ame-011432 Astyanax mexicanus 75.41 0.00e+00 649.00
IUUC-Bgr-012218 Blumeria graminis 28.34 5.00e-31 128.00
IUUC-Bta-012829 Bos taurus 95.98 0.00e+00 771.00
IUUC-Bci-013953 Botrytis cinerea 30.31 8.00e-35 141.00
IUUC-Bdi-014351 Brachypodium distachyon 37.68 4.00e-58 218.00
IUUC-Bol-016514 Brassica oleracea 34.69 4.00e-54 205.00
IUUC-Bra-017876 Brassica rapa 34.89 4.00e-56 211.00
IUUC-Cel-018569 Caenorhabditis elegans 32.28 3.00e-48 186.00
IUUC-Cja-019468 Callithrix jacchus 95.51 0.00e+00 752.00
IUUC-Cfa-020471 Canis familiaris 95.51 0.00e+00 744.00
IUUC-Cre-022614 Chlamydomonas reinhardtii 31.22 7.00e-39 154.00
IUUC-Csa-023989 Chlorocebus sabaeus 95.51 0.00e+00 755.00
IUUC-Cho-024426 Choloepus hoffmanni 91.43 3.00e-157 547.00
IUUC-Cin-025789 Ciona intestinalis 43.17 3.00e-96 345.00
IUUC-Cne-027063 Cryptococcus neoformans 24.74 1.00e-21 97.40
IUUC-Dre-027907 Danio rerio 76.60 0.00e+00 664.00
IUUC-Dno-029225 Dasypus novemcinctus 94.56 0.00e+00 763.00
IUUC-Dor-031082 Dipodomys ordii 78.25 1.00e-168 585.00
IUUC-Dse-031308 Dothistroma septosporum 27.53 5.00e-34 138.00
IUUC-Dme-032189 Drosophila melanogaster 41.75 6.00e-92 330.00
IUUC-Ete-032247 Echinops telfairi 87.71 0.00e+00 700.00
IUUC-Eca-034285 Equus caballus 95.51 0.00e+00 768.00
IUUC-Eeu-035322 Erinaceus europaeus 85.18 0.00e+00 643.00
IUUC-Fca-036114 Felis catus 95.51 0.00e+00 766.00
IUUC-Fal-036891 Ficedula albicollis 85.88 4.00e-173 600.00
IUUC-Fox-037965 Fusarium oxysporum 25.37 1.00e-33 137.00
IUUC-Fso-038244 Fusarium solani 26.64 1.00e-33 137.00
IUUC-Gmo-039040 Gadus morhua 75.65 0.00e+00 671.00
IUUC-Gga-040610 Gallus gallus 83.69 0.00e+00 710.00
IUUC-Gac-042117 Gasterosteus aculeatus 74.94 0.00e+00 650.00
IUUC-Gma-043146 Glycine max 37.17 5.00e-66 244.00
IUUC-Ggo-045179 Gorilla gorilla 95.27 0.00e+00 748.00
IUUC-Hsa-046114 Homo sapiens 95.98 0.00e+00 753.00
IUUC-Hvu-047331 Hordeum vulgare 34.87 1.00e-53 203.00
IUUC-Itr-048275 Ictidomys tridecemlineatus 95.98 0.00e+00 770.00
IUUC-Kpa-049304 Komagataella pastoris 28.67 2.00e-40 159.00
IUUC-Lch-050655 Latimeria chalumnae 77.31 7.00e-143 499.00
IUUC-Lpe-051675 Leersia perrieri 35.80 1.00e-58 221.00
IUUC-Loc-052868 Lepisosteus oculatus 81.09 0.00e+00 669.00
IUUC-Lma-053258 Leptosphaeria maculans 27.34 2.00e-31 132.00
IUUC-Laf-053993 Loxodonta africana 94.09 0.00e+00 763.00
IUUC-Mcc-055128 Macaca mulatta 78.01 2.00e-170 591.00
IUUC-Meu-056501 Macropus eugenii 78.55 4.00e-162 563.00
IUUC-Mor-057114 Magnaporthe oryzae 26.22 4.00e-25 109.00
IUUC-Mtr-058367 Medicago truncatula 35.97 1.00e-59 223.00
IUUC-Mla-059107 Melampsora laricipopulina 27.00 8.00e-29 121.00
IUUC-Mga-059745 Meleagris gallopavo 81.65 0.00e+00 683.00
IUUC-Mvi-060362 Microbotryum violaceum 30.65 3.00e-36 146.00
IUUC-Mdo-062257 Monodelphis domestica 85.68 0.00e+00 720.00
IUUC-Mmu-063546 Mus musculus 92.91 0.00e+00 755.00
IUUC-Mac-065540 Musa acuminata 34.44 5.00e-55 208.00
IUUC-Mpu-066284 Mustela putorius furo 96.45 0.00e+00 775.00
IUUC-Mlu-067241 Myotis lucifugus 94.80 0.00e+00 764.00
IUUC-Nfi-068260 Neosartorya fischeri 27.56 8.00e-34 138.00
IUUC-Ncr-068719 Neurospora crassa 26.58 2.00e-26 113.00
IUUC-Nle-068981 Nomascus leucogenys 95.51 0.00e+00 734.00
IUUC-Opr-071218 Ochotona princeps 86.68 0.00e+00 662.00
IUUC-Ont-071646 Oreochromis niloticus 76.63 0.00e+00 668.00
IUUC-Oan-073453 Ornithorhynchus anatinus 88.65 0.00e+00 754.00
IUUC-Ocu-074008 Oryctolagus cuniculus 96.22 0.00e+00 771.00
IUUC-Oba-075712 Oryza barthii 31.73 1.00e-42 167.00
IUUC-Obr-076721 Oryza brachyantha 35.48 4.00e-59 221.00
IUUC-Ogl-077229 Oryza glaberrima 35.56 3.00e-58 219.00
IUUC-Ogu-078977 Oryza glumaepatula 31.73 8.00e-43 167.00
IUUC-Oin-079683 Oryza indica 35.56 1.00e-58 220.00
IUUC-Olo-080291 Oryza longistaminata 31.99 1.00e-29 123.00
IUUC-Ome-081834 Oryza meridionalis 35.80 2.00e-59 223.00
IUUC-Oni-082507 Oryza nivara 34.45 2.00e-54 206.00
IUUC-Opu-083396 Oryza punctata 35.56 6.00e-59 221.00
IUUC-Oru-085220 Oryza rufipogon 35.00 5.00e-54 205.00
IUUC-Osa-085767 Oryza sativa 35.56 1.00e-58 220.00
IUUC-Ola-087420 Oryzias latipes 76.60 0.00e+00 666.00
IUUC-Olu-087740 Ostreococcus lucimarinus 27.88 8.00e-36 144.00
IUUC-Oga-088264 Otolemur garnettii 94.56 0.00e+00 745.00
IUUC-Oar-089335 Ovis aries 95.51 0.00e+00 766.00
IUUC-Ptr-091320 Pan troglodytes 95.98 0.00e+00 753.00
IUUC-Pan-092833 Papio anubis 95.51 0.00e+00 754.00
IUUC-Psi-093504 Pelodiscus sinensis 87.00 0.00e+00 734.00
IUUC-Pma-094189 Petromyzon marinus 69.10 9.00e-171 592.00
IUUC-Pno-094929 Phaeosphaeria nodorum 26.91 4.00e-32 132.00
IUUC-Ppa-095429 Physcomitrella patens 36.08 8.00e-66 244.00
IUUC-Pfo-096337 Poecilia formosa 74.94 0.00e+00 669.00
IUUC-Pab-097571 Pongo abelii 95.51 0.00e+00 752.00
IUUC-Pop-099977 Populus trichocarpa 36.06 1.00e-63 236.00
IUUC-Pca-100394 Procavia capensis 88.51 0.00e+00 664.00
IUUC-Ppe-101848 Prunus persica 35.58 2.00e-60 226.00
IUUC-Pva-102921 Pteropus vampyrus 93.52 5.00e-113 400.00
IUUC-Pgr-103637 Puccinia graminis 27.96 2.00e-33 137.00
IUUC-Ptt-103781 Puccinia triticina 27.53 1.00e-33 137.00
IUUC-Pte-104135 Pyrenophora teres 26.30 7.00e-32 133.00
IUUC-Pyt-104609 Pyrenophora triticirepentis 26.15 4.00e-31 129.00
IUUC-Rno-105114 Rattus norvegicus 92.67 0.00e+00 754.00
IUUC-Sce-106401 Saccharomyces cerevisiae 30.18 4.00e-39 155.00
IUUC-Sha-107122 Sarcophilus harrisii 85.89 0.00e+00 691.00
IUUC-Sja-107766 Schizosaccharomyces japonicus 31.54 5.00e-47 181.00
IUUC-Spo-108134 Schizosaccharomyces pombe 29.29 4.00e-38 152.00
IUUC-Ssl-108398 Sclerotinia sclerotiorum 29.53 2.00e-35 143.00
IUUC-Smo-108720 Selaginella moellendorffii 34.29 2.00e-58 219.00
IUUC-Sit-110311 Setaria italica 37.08 6.00e-58 218.00
IUUC-Sly-111023 Solanum lycopersicum 33.41 5.00e-55 208.00
IUUC-Stu-112778 Solanum tuberosum 36.28 2.00e-61 229.00
IUUC-Sar-113596 Sorex araneus 77.54 3.00e-173 600.00
IUUC-Sbi-114193 Sorghum bicolor 36.25 7.00e-59 221.00
IUUC-Sre-115002 Sporisorium reilianum 25.43 2.00e-11 63.90
IUUC-Ssc-116066 Sus scrofa 96.22 0.00e+00 769.00
IUUC-Tgu-117048 Taeniopygia guttata 84.84 0.00e+00 638.00
IUUC-Tsy-119573 Tarsius syrichta 61.72 9.00e-129 452.00
IUUC-Tni-119820 Tetraodon nigroviridis 75.30 0.00e+00 668.00
IUUC-Tca-121605 Theobroma cacao 36.54 8.00e-62 231.00
IUUC-Tre-121947 Trichoderma reesei 26.92 4.00e-34 139.00
IUUC-Tvi-122481 Trichoderma virens 27.14 1.00e-35 144.00
IUUC-Tae-125861 Triticum aestivum 34.44 7.00e-58 218.00
IUUC-Tur-126586 Triticum urartu 35.13 2.00e-55 209.00
IUUC-Tme-126900 Tuber melanosporum 32.62 6.00e-49 188.00
IUUC-Tbe-127736 Tupaia belangeri 72.36 2.00e-151 528.00
IUUC-Ttr-129041 Tursiops truncatus 84.16 0.00e+00 659.00
IUUC-Vpa-130260 Vicugna pacos 96.45 0.00e+00 773.00
IUUC-Vvi-131009 Vitis vinifera 35.48 4.00e-60 225.00
IUUC-Xtr-132083 Xenopus tropicalis 81.09 0.00e+00 674.00
IUUC-Xma-133094 Xiphophorus maculatus 74.23 0.00e+00 663.00
IUUC-Yli-134531 Yarrowia lipolytica 23.35 2.00e-18 87.00
IUUC-Zma-135509 Zea mays 34.76 2.00e-59 222.00
Created Date 25-Jun-2017

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