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Tag Content
UUCD2 ID IUUC-Cfa-020622
UUCD1 version UUC-CaF-00923
Ensembl Protein ID ENSCAFP00000022077.3
UniProt Accession E2RGH5; E2RGH5_CANLF
Genbank Protein ID ENSCAFP00000022077
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03026318
Gene Name UBA1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000014944.4 ENSCAFT00000043023.2 ENSCAFP00000042252.1
ENSCAFG00000014944.4 ENSCAFT00000023784.3 ENSCAFP00000022077.3
Status Unreviewed
Classification
Family E-Value Score Start End
E1 1.30e-224 746.2 451 930
Active Site
Position(s) Description Evidence
632 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU10132}
Domain Profile

   E1
   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD+Q++++G++ qekl+++k++lvGag++GcEllKn++++G+     g+i v+Dmdt+e+snlnrqFLfr++dv k K+++aa+a++++
   Q: 451  YDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLgcgegGEIVVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQM 539
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkt 170
           np+++v++h++++ +++e+i+   Ff+++d+V++aldn++ar++++r+c+++r+pl+esgtlG++G+v+v+i+ lte+ys+s+dpp+k+
   Q: 540  NPHIRVTSHQNRVGPDTERIYdddFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKS 628
           ***************************************************************************************** PP
   S: 171  iPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafak 247
           iP+ctlk++pna+eht++wa            + +n++l ++++++e++ +l+ ++++e++++v+++l+ ++++++++++++a++++++
   Q: 629  IPICTLKNFPNAIEHTLQWArdefeglfkqpaENVNQYL-TDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHT 716
           ***************************************.999999******************************************* PP
   S: 248  ttinsikqllksfecdivtkskspfwv..........................................sfcsnaealqvp........ 286
           +++n+i+qll++f++d++t+s++pfw+                                           + ++ +++qvp        
   Q: 717  QYSNNIRQLLHNFPPDQLTSSGAPFWSgpkrcphpltfdvnnplhldyvmaaanlfaqtygltgsqdraAVATLLRSVQVPeftpksgv 805
           *******************************************************************9988888888887744444444 PP
   S: 287  ekvekdeevvkasap...lylllral..erfekkkgrkpgelsfekddds.avdlvtaaanlraeslgiepkldddlikeiagniipai 369
           + +++d+e ++a+a+   +++l   l   + ++ +++    l     dds    ++ aa+  rae+++i+p +d+++ k iag+iipai
   Q: 806  KIHVSDQELQSANASvdlSSALPPHLppPSPCNSPSLHLFPLAHAAXDDSnFHMFIVAASTSRAENYDIPP-ADRHKSKLIAGKIIPAI 893
           55555555555555565533332222113445555555555666666777766688889999*********.***************** PP
   S: 370  attnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           att+a+v Gl+++E++Kvv g  + + +kn fl++a+
   Q: 894  ATTTAAVVGLVCLELYKVVHGhrQLDSYKNGFLNLAL 930
           *********************999*********9875 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MSSSPLSKKR RVSGPDPKPG SNCSPAHSVL SEVPSVPTNG MAKNGSEADI DEGLYSRQLY 60
VLGHEAMKRL QTSSVLVSGL RGLGVEIAKN IILGGVKAVT LHDQGTAQWA DLSSQFYLRE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020622|E1,E1_ThiF|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GACTGGAGTC TCTCCCTCAT GCTGGGCTGG GGAGAAAGGC GAATGGCCTA GTGGTCAGCA 60
GCATGGATTG CAAGCCAGAC CACCTGGGTT CAGATCTTAG CTCTGACAGC TGTGTGACCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020622|E1,E1_ThiF|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like
PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2
Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys
PRINTS

PR01849--UBIQUITINACT
SMART

SM00985--UBA_e1_C
Gene Ontology

GO:0005829--C:cytosol
GO:0030057--C:desmosome
GO:0010008--C:endosome membrane
GO:0070062--C:extracellular exosome
GO:0000792--C:heterochromatin
GO:0005765--C:lysosomal membrane
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0030867--C:rough endoplasmic reticulum membrane
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0004839--F:ubiquitin activating enzyme activity
GO:0006974--P:cellular response to DNA damage stimulus
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000367 Aegilops tauschii 45.29 0.00e+00 833.00
IUUC-Aml-001311 Ailuropoda melanoleuca 95.20 0.00e+00 2048.00
IUUC-Atr-002684 Amborella trichopoda 44.89 0.00e+00 869.00
IUUC-Aca-004620 Anolis carolinensis 78.98 0.00e+00 1736.00
IUUC-Aly-005515 Arabidopsis lyrata 44.66 0.00e+00 884.00
IUUC-Ath-006891 Arabidopsis thaliana 45.05 0.00e+00 892.00
IUUC-Ago-007873 Ashbya gossypii 53.50 0.00e+00 1028.00
IUUC-Acl-008181 Aspergillus clavatus 52.84 0.00e+00 1027.00
IUUC-Afl-008455 Aspergillus flavus 52.87 0.00e+00 994.00
IUUC-Afu-009065 Aspergillus fumigatus 52.30 0.00e+00 1045.00
IUUC-Ani-009371 Aspergillus nidulans 52.32 0.00e+00 1013.00
IUUC-Ang-009737 Aspergillus niger 52.58 0.00e+00 1029.00
IUUC-Aor-010007 Aspergillus oryzae 52.87 0.00e+00 994.00
IUUC-Ate-010466 Aspergillus terreus 52.54 0.00e+00 1061.00
IUUC-Ame-010933 Astyanax mexicanus 77.05 0.00e+00 1632.00
IUUC-Bgr-012281 Blumeria graminis 52.84 0.00e+00 1052.00
IUUC-Bta-012767 Bos taurus 94.42 0.00e+00 2033.00
IUUC-Bci-013721 Botrytis cinerea 53.33 0.00e+00 996.00
IUUC-Bdi-014335 Brachypodium distachyon 45.06 0.00e+00 869.00
IUUC-Bol-015665 Brassica oleracea 43.58 0.00e+00 873.00
IUUC-Bra-017252 Brassica rapa 43.57 0.00e+00 878.00
IUUC-Cel-018260 Caenorhabditis elegans 48.51 0.00e+00 926.00
IUUC-Cja-019152 Callithrix jacchus 95.27 0.00e+00 2047.00
IUUC-Cpo-022526 Cavia porcellus 94.05 0.00e+00 2002.00
IUUC-Cre-022702 Chlamydomonas reinhardtii 44.60 0.00e+00 818.00
IUUC-Csa-023780 Chlorocebus sabaeus 95.09 0.00e+00 2044.00
IUUC-Cho-024896 Choloepus hoffmanni 88.28 2.00e-119 423.00
IUUC-Cin-025790 Ciona intestinalis 62.02 0.00e+00 1318.00
IUUC-Csv-026084 Ciona savignyi 59.01 0.00e+00 1291.00
IUUC-Cgl-026512 Colletotrichum gloeosporioides 53.33 0.00e+00 1064.00
IUUC-Cne-026960 Cryptococcus neoformans 54.96 0.00e+00 1088.00
IUUC-Cme-027290 Cyanidioschyzon merolae 43.95 0.00e+00 798.00
IUUC-Dre-028149 Danio rerio 77.15 0.00e+00 1670.00
IUUC-Dno-028884 Dasypus novemcinctus 94.52 0.00e+00 2038.00
IUUC-Dor-030229 Dipodomys ordii 91.86 0.00e+00 1984.00
IUUC-Dse-031524 Dothistroma septosporum 51.35 0.00e+00 1038.00
IUUC-Dme-032045 Drosophila melanogaster 59.76 0.00e+00 1251.00
IUUC-Ete-032544 Echinops telfairi 85.52 0.00e+00 883.00
IUUC-Eca-033330 Equus caballus 95.65 0.00e+00 2062.00
IUUC-Fca-036255 Felis catus 96.79 0.00e+00 2051.00
IUUC-Fal-037445 Ficedula albicollis 47.83 0.00e+00 868.00
IUUC-Fox-038007 Fusarium oxysporum 51.79 2.00e-157 549.00
IUUC-Fso-038339 Fusarium solani 53.37 0.00e+00 1027.00
IUUC-Gmo-039338 Gadus morhua 73.71 0.00e+00 1567.00
IUUC-Ggr-039823 Gaeumannomyces graminis 53.37 0.00e+00 1084.00
IUUC-Gga-040365 Gallus gallus 47.35 0.00e+00 799.00
IUUC-Gac-041773 Gasterosteus aculeatus 73.61 0.00e+00 1563.00
IUUC-Gma-043198 Glycine max 43.66 0.00e+00 853.00
IUUC-Ggo-045336 Gorilla gorilla 95.46 0.00e+00 2026.00
IUUC-Hsa-045982 Homo sapiens 95.27 0.00e+00 2024.00
IUUC-Hvu-047418 Hordeum vulgare 45.32 0.00e+00 856.00
IUUC-Itr-048460 Ictidomys tridecemlineatus 94.80 0.00e+00 2041.00
IUUC-Kpa-049112 Komagataella pastoris 51.23 0.00e+00 1000.00
IUUC-Lch-050371 Latimeria chalumnae 78.19 0.00e+00 1724.00
IUUC-Lpe-051299 Leersia perrieri 43.91 0.00e+00 867.00
IUUC-Loc-052936 Lepisosteus oculatus 79.23 0.00e+00 1714.00
IUUC-Lma-053315 Leptosphaeria maculans 52.19 0.00e+00 1060.00
IUUC-Laf-053948 Loxodonta africana 91.97 0.00e+00 1977.00
IUUC-Mcc-055843 Macaca mulatta 95.37 0.00e+00 2054.00
IUUC-Meu-056258 Macropus eugenii 85.16 0.00e+00 1847.00
IUUC-Mor-057269 Magnaporthe oryzae 53.51 0.00e+00 1063.00
IUUC-Mpo-057435 Magnaporthe poae 53.42 0.00e+00 1048.00
IUUC-Mtr-058572 Medicago truncatula 43.56 0.00e+00 835.00
IUUC-Mla-059176 Melampsora laricipopulina 55.04 0.00e+00 1071.00
IUUC-Mga-060052 Meleagris gallopavo 49.70 0.00e+00 735.00
IUUC-Mvi-060437 Microbotryum violaceum 52.89 0.00e+00 1034.00
IUUC-Mmr-061405 Microcebus murinus 92.72 0.00e+00 1980.00
IUUC-Mdo-062032 Monodelphis domestica 83.60 0.00e+00 1821.00
IUUC-Mmu-063280 Mus musculus 92.91 0.00e+00 1985.00
IUUC-Mac-065505 Musa acuminata 44.88 0.00e+00 852.00
IUUC-Mpu-066409 Mustela putorius furo 96.22 0.00e+00 2074.00
IUUC-Mlu-067217 Myotis lucifugus 93.38 0.00e+00 2009.00
IUUC-Nfi-068407 Neosartorya fischeri 52.59 0.00e+00 1024.00
IUUC-Ncr-068698 Neurospora crassa 53.79 0.00e+00 1073.00
IUUC-Nle-070072 Nomascus leucogenys 89.88 0.00e+00 1895.00
IUUC-Ont-071671 Oreochromis niloticus 76.67 0.00e+00 1642.00
IUUC-Oan-073306 Ornithorhynchus anatinus 48.93 0.00e+00 708.00
IUUC-Ocu-074544 Oryctolagus cuniculus 93.95 0.00e+00 2029.00
IUUC-Oba-075120 Oryza barthii 44.54 0.00e+00 851.00
IUUC-Obr-076557 Oryza brachyantha 45.31 0.00e+00 847.00
IUUC-Ogl-077887 Oryza glaberrima 44.54 0.00e+00 853.00
IUUC-Ogu-078305 Oryza glumaepatula 43.57 0.00e+00 860.00
IUUC-Oin-080154 Oryza indica 43.48 0.00e+00 860.00
IUUC-Olo-081089 Oryza longistaminata 43.67 0.00e+00 862.00
IUUC-Ome-081942 Oryza meridionalis 44.64 0.00e+00 852.00
IUUC-Oni-082365 Oryza nivara 44.54 0.00e+00 854.00
IUUC-Opu-083977 Oryza punctata 44.71 0.00e+00 853.00
IUUC-Oru-084469 Oryza rufipogon 43.67 0.00e+00 864.00
IUUC-Osa-085949 Oryza sativa 44.74 0.00e+00 860.00
IUUC-Ola-087002 Oryzias latipes 75.91 0.00e+00 1633.00
IUUC-Olu-087687 Ostreococcus lucimarinus 43.82 0.00e+00 794.00
IUUC-Oga-088594 Otolemur garnettii 94.71 0.00e+00 2008.00
IUUC-Oar-090068 Ovis aries 94.15 0.00e+00 2026.00
IUUC-Pan-092114 Papio anubis 95.56 0.00e+00 2059.00
IUUC-Pma-094214 Petromyzon marinus 58.14 4.00e-53 200.00
IUUC-Pno-095154 Phaeosphaeria nodorum 51.76 0.00e+00 1063.00
IUUC-Ppa-095416 Physcomitrella patens 44.44 0.00e+00 867.00
IUUC-Pfo-097184 Poecilia formosa 75.62 0.00e+00 1624.00
IUUC-Pab-097861 Pongo abelii 95.09 0.00e+00 2009.00
IUUC-Pop-098934 Populus trichocarpa 44.32 0.00e+00 888.00
IUUC-Pca-100347 Procavia capensis 88.31 0.00e+00 1573.00
IUUC-Ppe-102012 Prunus persica 43.49 0.00e+00 870.00
IUUC-Pva-102584 Pteropus vampyrus 95.09 0.00e+00 2061.00
IUUC-Pgr-103336 Puccinia graminis 53.26 0.00e+00 1046.00
IUUC-Ptt-103939 Puccinia triticina 53.20 0.00e+00 1032.00
IUUC-Pte-104200 Pyrenophora teres 52.38 0.00e+00 1060.00
IUUC-Pyt-104441 Pyrenophora triticirepentis 51.29 0.00e+00 1048.00
IUUC-Rno-105462 Rattus norvegicus 93.76 0.00e+00 1978.00
IUUC-Sce-106245 Saccharomyces cerevisiae 50.87 0.00e+00 1044.00
IUUC-Sha-107142 Sarcophilus harrisii 85.26 0.00e+00 1872.00
IUUC-Sja-107841 Schizosaccharomyces japonicus 54.92 0.00e+00 1108.00
IUUC-Spo-108034 Schizosaccharomyces pombe 52.40 0.00e+00 1047.00
IUUC-Ssl-108497 Sclerotinia sclerotiorum 53.91 0.00e+00 1022.00
IUUC-Smo-109211 Selaginella moellendorffii 45.49 0.00e+00 864.00
IUUC-Sit-110281 Setaria italica 44.79 0.00e+00 872.00
IUUC-Sly-110914 Solanum lycopersicum 44.18 0.00e+00 873.00
IUUC-Stu-112109 Solanum tuberosum 44.28 0.00e+00 881.00
IUUC-Sar-113737 Sorex araneus 93.95 0.00e+00 2014.00
IUUC-Sbi-114089 Sorghum bicolor 44.79 0.00e+00 868.00
IUUC-Sre-115148 Sporisorium reilianum 54.00 0.00e+00 1065.00
IUUC-Ssc-115777 Sus scrofa 95.94 0.00e+00 2060.00
IUUC-Tru-118742 Takifugu rubripes 75.43 0.00e+00 1576.00
IUUC-Tsy-119485 Tarsius syrichta 97.36 2.00e-174 605.00
IUUC-Tni-120401 Tetraodon nigroviridis 75.81 0.00e+00 1580.00
IUUC-Tca-121672 Theobroma cacao 43.56 0.00e+00 872.00
IUUC-Tre-122009 Trichoderma reesei 52.75 0.00e+00 1025.00
IUUC-Tvi-122259 Trichoderma virens 53.33 0.00e+00 1013.00
IUUC-Tae-125113 Triticum aestivum 45.29 0.00e+00 833.00
IUUC-Tur-126330 Triticum urartu 45.28 0.00e+00 871.00
IUUC-Tme-127055 Tuber melanosporum 52.94 0.00e+00 984.00
IUUC-Tbe-127487 Tupaia belangeri 95.90 0.00e+00 1043.00
IUUC-Ttr-128331 Tursiops truncatus 94.90 0.00e+00 2025.00
IUUC-Uma-129387 Ustilago maydis 54.28 0.00e+00 1063.00
IUUC-Vda-129977 Verticillium dahliae 52.93 0.00e+00 976.00
IUUC-Vvi-130857 Vitis vinifera 44.47 0.00e+00 875.00
IUUC-Xtr-132026 Xenopus tropicalis 62.14 0.00e+00 1222.00
IUUC-Xma-133805 Xiphophorus maculatus 75.43 0.00e+00 1602.00
IUUC-Yli-134547 Yarrowia lipolytica 53.39 0.00e+00 1077.00
IUUC-Zma-135052 Zea mays 44.85 0.00e+00 870.00
Created Date 25-Jun-2017

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