iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040547

Ensembl Protein ID

ENSGALP00000064045.1

UniProt Accession

A0A1L1RYV5; A0A1L1RYV5_CHICK

Genbank Protein ID

ENSGALP00000064045

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

AADN04000298

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000016187.6	ENSGALT00000026088.6	ENSGALP00000064045.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-06	28.8	196	233

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+ + f  ++  +ll+s+s+D+t+++W + tg  
   Q: 196  GHEEFVSRI-FvvPNypDLLLSASGDCTLRLWKYETGEE 233
           566666777.778444799**************999875 PP

Organism

Gallus gallus

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MEGGSGRSPG PGPALALRGT LMAVGGGSRL LAARRGERRD DTVFVYDCAS VEKKALGNKG 60
QDKQPADKGS DNILAFAFSP SGDYFVLTDD NKHLILFRTK PSWECISIRP VNRRCTSLII 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTATTTAT TTATTTTTAT CGCATTACCC TTCCCCGTGC GTCATCATCG TTTCGCCTGC 60
GGTGACGTCC ACACTCTGCG CCTCCATCGC ACGTGGAGGG GGAATGGAGG GCGGATCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0036265--P:RNA (guanine-N7)-methylation
GO:0030488--P:tRNA methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	25.37	7.00e-09	54.70
IUUC-Apl-003975	Anas platyrhynchos	84.74	0.00e+00	628.00
IUUC-Aca-005170	Anolis carolinensis	67.11	7.00e-130	456.00
IUUC-Aly-005769	Arabidopsis lyrata	29.85	6.00e-25	108.00
IUUC-Ath-006733	Arabidopsis thaliana	30.65	2.00e-23	103.00
IUUC-Acl-008151	Aspergillus clavatus	26.80	4.00e-13	69.30
IUUC-Afl-008518	Aspergillus flavus	42.70	1.00e-12	67.00
IUUC-Afu-009102	Aspergillus fumigatus	28.74	2.00e-12	67.00
IUUC-Ani-009442	Aspergillus nidulans	28.33	7.00e-14	72.00
IUUC-Aor-010133	Aspergillus oryzae	30.05	5.00e-14	72.40
IUUC-Ate-010465	Aspergillus terreus	29.27	4.00e-15	75.90
IUUC-Ame-010613	Astyanax mexicanus	44.69	7.00e-93	333.00
IUUC-Bgr-012067	Blumeria graminis	33.33	5.00e-15	75.90
IUUC-Bta-012788	Bos taurus	56.58	3.00e-128	451.00
IUUC-Bdi-014458	Brachypodium distachyon	30.65	3.00e-17	82.80
IUUC-Bol-016398	Brassica oleracea	29.57	3.00e-25	108.00
IUUC-Bra-016644	Brassica rapa	35.71	1.00e-22	102.00
IUUC-Cpo-021963	Cavia porcellus	54.81	3.00e-119	421.00
IUUC-Csa-024148	Chlorocebus sabaeus	57.00	8.00e-111	393.00
IUUC-Cne-026834	Cryptococcus neoformans	37.82	4.00e-21	95.90
IUUC-Dre-028427	Danio rerio	46.97	1.00e-94	340.00
IUUC-Dno-028881	Dasypus novemcinctus	50.24	3.00e-117	414.00
IUUC-Dor-030522	Dipodomys ordii	54.91	2.00e-127	448.00
IUUC-Dme-032136	Drosophila melanogaster	40.48	4.00e-24	105.00
IUUC-Fca-035833	Felis catus	58.47	2.00e-128	451.00
IUUC-Fal-037497	Ficedula albicollis	77.19	3.00e-169	587.00
IUUC-Gac-041761	Gasterosteus aculeatus	41.29	3.00e-79	288.00
IUUC-Gma-043722	Glycine max	31.03	4.00e-22	99.00
IUUC-Ggo-045340	Gorilla gorilla	56.76	8.00e-120	423.00
IUUC-Hsa-046403	Homo sapiens	58.42	2.00e-119	422.00
IUUC-Hvu-047643	Hordeum vulgare	29.89	5.00e-18	85.50
IUUC-Itr-048103	Ictidomys tridecemlineatus	56.79	2.00e-128	452.00
IUUC-Kpa-049283	Komagataella pastoris	34.67	6.00e-19	88.20
IUUC-Lch-050682	Latimeria chalumnae	51.10	7.00e-117	413.00
IUUC-Lpe-050712	Leersia perrieri	30.29	1.00e-23	103.00
IUUC-Loc-052599	Lepisosteus oculatus	52.48	1.00e-123	436.00
IUUC-Laf-054390	Loxodonta africana	54.93	2.00e-131	461.00
IUUC-Mcc-054747	Macaca mulatta	57.25	2.00e-118	418.00
IUUC-Mtr-058600	Medicago truncatula	34.30	6.00e-26	111.00
IUUC-Mla-059129	Melampsora laricipopulina	26.88	2.00e-11	62.40
IUUC-Mga-059876	Meleagris gallopavo	93.92	0.00e+00	711.00
IUUC-Mvi-060359	Microbotryum violaceum	29.63	5.00e-11	62.80
IUUC-Mmr-061518	Microcebus murinus	56.86	2.00e-123	434.00
IUUC-Mac-065417	Musa acuminata	27.80	3.00e-21	95.90
IUUC-Nfi-068402	Neosartorya fischeri	26.77	5.00e-12	65.50
IUUC-Nle-069914	Nomascus leucogenys	53.07	2.00e-111	395.00
IUUC-Ont-071555	Oreochromis niloticus	42.11	2.00e-83	302.00
IUUC-Oan-072951	Ornithorhynchus anatinus	60.36	2.00e-137	481.00
IUUC-Ocu-074679	Oryctolagus cuniculus	56.79	3.00e-121	428.00
IUUC-Oba-075355	Oryza barthii	27.63	5.00e-14	72.00
IUUC-Obr-076769	Oryza brachyantha	28.84	4.00e-25	108.00
IUUC-Ogl-077168	Oryza glaberrima	31.68	1.00e-24	107.00
IUUC-Ogu-078275	Oryza glumaepatula	27.24	1.00e-13	70.90
IUUC-Oin-079207	Oryza indica	31.68	1.00e-24	107.00
IUUC-Oni-082437	Oryza nivara	24.48	1.00e-13	71.20
IUUC-Opu-084031	Oryza punctata	32.18	5.00e-23	102.00
IUUC-Oru-084380	Oryza rufipogon	27.24	3.00e-13	69.70
IUUC-Osa-085327	Oryza sativa	31.30	8.00e-24	104.00
IUUC-Ola-086716	Oryzias latipes	39.42	2.00e-72	266.00
IUUC-Olu-087708	Ostreococcus lucimarinus	24.38	5.00e-16	78.20
IUUC-Oar-090239	Ovis aries	57.53	3.00e-126	444.00
IUUC-Ptr-090851	Pan troglodytes	56.76	5.00e-120	424.00
IUUC-Pan-092558	Papio anubis	55.01	3.00e-110	391.00
IUUC-Psi-093792	Pelodiscus sinensis	72.55	2.00e-163	568.00
IUUC-Ppa-095757	Physcomitrella patens	36.09	4.00e-18	85.50
IUUC-Pfo-096465	Poecilia formosa	42.78	1.00e-87	316.00
IUUC-Pab-097722	Pongo abelii	56.89	5.00e-121	427.00
IUUC-Pop-098979	Populus trichocarpa	34.22	5.00e-18	85.10
IUUC-Pca-100753	Procavia capensis	54.01	2.00e-91	328.00
IUUC-Ppe-101515	Prunus persica	28.74	1.00e-17	84.00
IUUC-Sja-107780	Schizosaccharomyces japonicus	29.65	2.00e-13	70.10
IUUC-Spo-108251	Schizosaccharomyces pombe	26.62	3.00e-11	62.80
IUUC-Smo-108938	Selaginella moellendorffii	33.33	1.00e-20	94.40
IUUC-Sit-110020	Setaria italica	29.96	7.00e-23	101.00
IUUC-Sly-111543	Solanum lycopersicum	27.33	2.00e-24	106.00
IUUC-Stu-111925	Solanum tuberosum	26.43	7.00e-23	101.00
IUUC-Sbi-114061	Sorghum bicolor	31.50	2.00e-22	99.80
IUUC-Tgu-117321	Taeniopygia guttata	78.36	1.00e-157	548.00
IUUC-Tru-118454	Takifugu rubripes	43.85	2.00e-84	305.00
IUUC-Tni-119894	Tetraodon nigroviridis	41.36	1.00e-76	280.00
IUUC-Tca-121746	Theobroma cacao	33.68	7.00e-20	91.30
IUUC-Tae-124459	Triticum aestivum	29.18	2.00e-18	87.00
IUUC-Tur-126254	Triticum urartu	24.55	1.00e-10	60.80
IUUC-Tbe-127683	Tupaia belangeri	73.81	9.00e-36	144.00
IUUC-Ttr-129056	Tursiops truncatus	54.50	1.00e-118	419.00
IUUC-Vvi-131428	Vitis vinifera	36.36	1.00e-19	90.90
IUUC-Xma-133605	Xiphophorus maculatus	44.18	1.00e-90	326.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence