iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028461

Ensembl Protein ID

ENSDARP00000081545.5

UniProt Accession

F1R0Z9; F1R0Z9_DANRE

Genbank Protein ID

ENSDARP00000081545

Protein Name

Intersectin 2b

Genbank Nucleotide ID

CR628334

Gene Name

itsn2b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000054973.6	ENSDART00000087111.6	ENSDARP00000081545.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.70e-47	157.8	1176	1227

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+++ydy+a+n+deL++ k  v+ v+  ++ + +W+kg  el+g  Gl+P n+v+
   Q: 1176 QVIAIYDYTAANEDELSFSKSQVINVL--DKSNPDWWKG--ELNGVTGLIPTNYVK 1227
           699************************..999*******..9*************8 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MNGGRSIWAI TPEERDKHDQ KFDSLLPAQG YVTGEKARNF FIQSGLPQPV LAAIWALADM 60
NKDGKMDRLE FSIAMKLIKM KLQGQNLPTA LPIIMKQPPV PAPTMPAAPL GMGAMPNVPM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCAGCCATG TTGTTTGTCT GACAGCGCCG TACAGCAACA GGTTGTCAAA GATTCTTTAT 60
ATAACATTGC GGAAATCATT TAAAGAAACC CCTACGGCCG ATGCTCTTTC ATTTAATTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

dre:445153

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011377	Astyanax mexicanus	80.31	0.00e+00	1430.00
IUUC-Bdi-014016	Brachypodium distachyon	31.10	2.00e-11	65.50
IUUC-Cme-027247	Cyanidioschyzon merolae	25.95	3.00e-13	70.50
IUUC-Mvi-060268	Microbotryum violaceum	29.90	3.00e-46	181.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence