iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023610

Ensembl Protein ID

ENSCSAP00000012124.1

UniProt Accession

A0A0D9RU35; A0A0D9RU35_CHLSB

Genbank Protein ID

ENSCSAP00000012124

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01086505

Gene Name

ERCC8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000016051.1	ENSCSAT00000014145.1	ENSCSAP00000012124.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-30	102.7	184	218
UBD/Beta-Prp	9.60e-41	139.8	161	361

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrt 32
           gH  ++ ++++    d +l+++s D  +k+WD+r+
   Q: 184  GHRQEILAVSWsprYDYILATASADSRVKLWDVRR 218
           8**********96543678*************986 PP

UBD/Beta-Prp

   S: 69   tgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgq.clee..............tlsghdgvvn 141
            g +   +++ dl++g+c h+l+gh +++l++s+sp +++ l+++s+d+ +++wd++  + cl +               ++ h+g vn
   Q: 161  VGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPrYDYILATASADSRVKLWDVRRASgCLITldqhngkksqavesANTAHNGKVN 249
           555666677889************************888999**************987636666************************ PP
   S: 142  cvvvhpdgnllvsGslDrtvrlWdlktgkllrtl....tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvk 226
           ++++ +dg  l + ++D+ +rlW++++g+           + ++  + +     + e+v + + +t+ ++ + +ge +  l+gh ++v 
   Q: 250  GLCFTSDGLHLLTVGTDNRMRLWNSSNGENTLVNygkvCNNSKKGLKFTVSCGCSSEFVFVPYGSTIAVYTVYSGEQITMLKGHYKTVD 338
           ********99*************996654333334444223444444444455559********************************* PP
   S: 227  svrfspnderlvsgssDgsiriW 249
           +  f +n + l+sgs D  i  W
   Q: 339  CCVFQSNFQELYSGSRDCNILAW 361
           *********************99 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MLGFLSARQT GLEDPLRLRR AESTRRVLGL ELNKDRDVER IHGGGINTLD IEPVEGRYML 60
SGGSDGVIVL YDLENSSRQS YYTCKAVCSI GRDHPDVHRY SVETVQWYPH DTGMFTSSSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAGTTCTGT CATGGCGACG TCCAGTACTC CAGCCGGTGT GAGGACACGC TATGCTGGGG 60
TTTTTGTCCG CGCGACAAAC GGGTTTGGAG GACCCTCTTC GCCTTCGGAG AGCAGAGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0016363--C:nuclear matrix
GO:0000109--C:nucleotide-excision repair complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006979--P:response to oxidative stress
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray
GO:0006283--P:transcription-coupled nucleotide-excision repair

KEGG

csab:103222012

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001170	Aegilops tauschii	30.09	7.00e-37	149.00
IUUC-Aml-002201	Ailuropoda melanoleuca	93.94	0.00e+00	787.00
IUUC-Atr-002784	Amborella trichopoda	37.18	6.00e-41	161.00
IUUC-Apl-003202	Anas platyrhynchos	81.32	0.00e+00	658.00
IUUC-Aca-004708	Anolis carolinensis	80.46	1.00e-176	612.00
IUUC-Aly-006144	Arabidopsis lyrata	30.15	4.00e-44	172.00
IUUC-Ath-006673	Arabidopsis thaliana	39.71	5.00e-45	175.00
IUUC-Acl-008195	Aspergillus clavatus	38.29	6.00e-43	168.00
IUUC-Afl-008406	Aspergillus flavus	36.36	6.00e-39	154.00
IUUC-Afu-008759	Aspergillus fumigatus	36.06	5.00e-40	158.00
IUUC-Ani-009380	Aspergillus nidulans	35.10	6.00e-41	161.00
IUUC-Ang-009820	Aspergillus niger	36.76	3.00e-39	155.00
IUUC-Aor-010092	Aspergillus oryzae	36.67	1.00e-43	170.00
IUUC-Ate-010491	Aspergillus terreus	36.30	2.00e-44	173.00
IUUC-Bta-012825	Bos taurus	93.95	0.00e+00	780.00
IUUC-Bci-013856	Botrytis cinerea	31.58	3.00e-52	199.00
IUUC-Bdi-014899	Brachypodium distachyon	32.84	4.00e-64	238.00
IUUC-Bol-015337	Brassica oleracea	37.93	9.00e-45	174.00
IUUC-Bra-018089	Brassica rapa	37.93	1.00e-44	174.00
IUUC-Cja-018725	Callithrix jacchus	96.97	0.00e+00	805.00
IUUC-Cfa-021162	Canis familiaris	94.44	0.00e+00	789.00
IUUC-Cpo-022190	Cavia porcellus	94.44	0.00e+00	792.00
IUUC-Cre-022960	Chlamydomonas reinhardtii	37.14	4.00e-40	159.00
IUUC-Cho-024689	Choloepus hoffmanni	92.70	0.00e+00	721.00
IUUC-Cin-025324	Ciona intestinalis	40.16	9.00e-81	293.00
IUUC-Csv-026059	Ciona savignyi	38.37	2.00e-73	269.00
IUUC-Cgl-026384	Colletotrichum gloeosporioides	33.23	1.00e-38	154.00
IUUC-Cme-027182	Cyanidioschyzon merolae	28.66	5.00e-13	69.70
IUUC-Dre-028696	Danio rerio	72.50	1.00e-176	612.00
IUUC-Dno-029102	Dasypus novemcinctus	94.44	0.00e+00	792.00
IUUC-Dor-030361	Dipodomys ordii	77.02	2.00e-179	621.00
IUUC-Dse-031167	Dothistroma septosporum	29.46	2.00e-44	173.00
IUUC-Ete-032856	Echinops telfairi	75.51	5.00e-178	616.00
IUUC-Eca-033611	Equus caballus	95.56	0.00e+00	683.00
IUUC-Eeu-034583	Erinaceus europaeus	71.72	3.00e-162	564.00
IUUC-Fca-036481	Felis catus	94.44	0.00e+00	791.00
IUUC-Fal-037327	Ficedula albicollis	77.94	3.00e-165	573.00
IUUC-Fox-037684	Fusarium oxysporum	30.52	1.00e-43	171.00
IUUC-Fso-038306	Fusarium solani	32.55	4.00e-54	205.00
IUUC-Gmo-039043	Gadus morhua	67.85	4.00e-163	567.00
IUUC-Ggr-039783	Gaeumannomyces graminis	33.67	8.00e-38	151.00
IUUC-Gga-041085	Gallus gallus	85.06	0.00e+00	632.00
IUUC-Gac-042328	Gasterosteus aculeatus	67.08	1.00e-158	552.00
IUUC-Gma-042916	Glycine max	32.01	8.00e-58	217.00
IUUC-Ggo-045627	Gorilla gorilla	91.04	0.00e+00	741.00
IUUC-Hsa-046028	Homo sapiens	100.00	0.00e+00	826.00
IUUC-Hvu-047678	Hordeum vulgare	32.06	2.00e-34	139.00
IUUC-Itr-048648	Ictidomys tridecemlineatus	95.20	0.00e+00	799.00
IUUC-Kpa-049386	Komagataella pastoris	30.33	2.00e-43	169.00
IUUC-Lch-050590	Latimeria chalumnae	79.31	4.00e-162	563.00
IUUC-Lpe-051725	Leersia perrieri	32.80	3.00e-35	142.00
IUUC-Loc-051788	Lepisosteus oculatus	74.23	2.00e-179	621.00
IUUC-Lma-053082	Leptosphaeria maculans	33.71	1.00e-54	206.00
IUUC-Laf-053809	Loxodonta africana	94.71	0.00e+00	790.00
IUUC-Mcc-054998	Macaca mulatta	99.29	9.00e-168	582.00
IUUC-Meu-055929	Macropus eugenii	77.39	0.00e+00	636.00
IUUC-Mor-057003	Magnaporthe oryzae	33.63	2.00e-48	186.00
IUUC-Mtr-057921	Medicago truncatula	32.03	5.00e-57	214.00
IUUC-Mga-059449	Meleagris gallopavo	65.59	8.00e-126	442.00
IUUC-Mmr-061609	Microcebus murinus	92.07	0.00e+00	743.00
IUUC-Mdo-062564	Monodelphis domestica	85.14	0.00e+00	724.00
IUUC-Mmu-063904	Mus musculus	89.67	0.00e+00	753.00
IUUC-Mac-064716	Musa acuminata	36.16	2.00e-40	159.00
IUUC-Mpu-066617	Mustela putorius furo	94.19	0.00e+00	789.00
IUUC-Mlu-067054	Myotis lucifugus	91.67	0.00e+00	768.00
IUUC-Nfi-068467	Neosartorya fischeri	36.90	1.00e-34	140.00
IUUC-Nle-069731	Nomascus leucogenys	100.00	0.00e+00	826.00
IUUC-Opr-070297	Ochotona princeps	68.62	1.00e-87	316.00
IUUC-Ont-072558	Oreochromis niloticus	70.32	2.00e-164	571.00
IUUC-Oan-072864	Ornithorhynchus anatinus	85.96	5.00e-27	111.00
IUUC-Ocu-074415	Oryctolagus cuniculus	95.20	0.00e+00	797.00
IUUC-Oba-075759	Oryza barthii	39.47	7.00e-43	168.00
IUUC-Obr-076387	Oryza brachyantha	37.91	6.00e-45	174.00
IUUC-Ogl-077924	Oryza glaberrima	40.60	2.00e-17	82.00
IUUC-Ogu-078186	Oryza glumaepatula	34.20	8.00e-63	234.00
IUUC-Oin-079389	Oryza indica	33.71	1.00e-46	179.00
IUUC-Olo-080916	Oryza longistaminata	28.43	3.00e-16	78.20
IUUC-Ome-081471	Oryza meridionalis	38.95	3.00e-40	159.00
IUUC-Oni-082449	Oryza nivara	38.95	5.00e-40	158.00
IUUC-Opu-083210	Oryza punctata	38.95	2.00e-42	166.00
IUUC-Oru-085159	Oryza rufipogon	39.47	5.00e-43	168.00
IUUC-Osa-085926	Oryza sativa	39.86	5.00e-33	133.00
IUUC-Ola-087084	Oryzias latipes	67.59	1.00e-165	575.00
IUUC-Olu-087853	Ostreococcus lucimarinus	28.35	4.00e-39	155.00
IUUC-Oga-089008	Otolemur garnettii	93.48	0.00e+00	780.00
IUUC-Oar-089259	Ovis aries	94.46	0.00e+00	783.00
IUUC-Ptr-091112	Pan troglodytes	99.24	0.00e+00	815.00
IUUC-Pan-092303	Papio anubis	100.00	8.00e-75	271.00
IUUC-Psi-093050	Pelodiscus sinensis	82.16	0.00e+00	697.00
IUUC-Pma-094259	Petromyzon marinus	56.19	6.00e-128	450.00
IUUC-Pno-094798	Phaeosphaeria nodorum	30.89	9.00e-51	194.00
IUUC-Ppa-095477	Physcomitrella patens	31.19	1.00e-53	203.00
IUUC-Pfo-096855	Poecilia formosa	67.16	1.00e-163	569.00
IUUC-Pab-098096	Pongo abelii	99.24	0.00e+00	820.00
IUUC-Pop-098800	Populus trichocarpa	36.40	3.00e-45	175.00
IUUC-Pca-100187	Procavia capensis	92.23	2.00e-113	402.00
IUUC-Ppe-101759	Prunus persica	36.00	2.00e-43	170.00
IUUC-Pva-102438	Pteropus vampyrus	78.05	2.00e-91	329.00
IUUC-Pte-104197	Pyrenophora teres	33.33	4.00e-50	192.00
IUUC-Pyt-104421	Pyrenophora triticirepentis	33.33	9.00e-50	191.00
IUUC-Rno-106087	Rattus norvegicus	90.43	0.00e+00	760.00
IUUC-Sce-106276	Saccharomyces cerevisiae	26.80	3.00e-12	66.60
IUUC-Sha-106831	Sarcophilus harrisii	82.41	0.00e+00	690.00
IUUC-Sja-107681	Schizosaccharomyces japonicus	33.07	4.00e-57	215.00
IUUC-Spo-108294	Schizosaccharomyces pombe	34.83	5.00e-64	238.00
IUUC-Ssl-108613	Sclerotinia sclerotiorum	32.67	5.00e-52	198.00
IUUC-Smo-109008	Selaginella moellendorffii	40.90	2.00e-76	279.00
IUUC-Sit-110300	Setaria italica	29.95	2.00e-52	199.00
IUUC-Sly-111441	Solanum lycopersicum	28.94	6.00e-45	174.00
IUUC-Stu-111995	Solanum tuberosum	28.74	4.00e-45	175.00
IUUC-Sar-113196	Sorex araneus	84.03	2.00e-130	458.00
IUUC-Sbi-113790	Sorghum bicolor	40.00	2.00e-43	170.00
IUUC-Ssc-115609	Sus scrofa	94.44	0.00e+00	794.00
IUUC-Tgu-116927	Taeniopygia guttata	79.70	0.00e+00	663.00
IUUC-Tru-118164	Takifugu rubripes	68.98	4.00e-171	593.00
IUUC-Tsy-119151	Tarsius syrichta	89.90	0.00e+00	741.00
IUUC-Tni-120896	Tetraodon nigroviridis	68.25	9.00e-162	562.00
IUUC-Tca-121592	Theobroma cacao	29.37	2.00e-45	176.00
IUUC-Tre-122023	Trichoderma reesei	34.73	4.00e-49	189.00
IUUC-Tvi-122507	Trichoderma virens	35.10	4.00e-50	192.00
IUUC-Tae-125730	Triticum aestivum	33.73	1.00e-59	223.00
IUUC-Tur-126092	Triticum urartu	30.29	3.00e-34	139.00
IUUC-Tbe-127422	Tupaia belangeri	71.35	2.00e-152	531.00
IUUC-Ttr-129097	Tursiops truncatus	91.41	0.00e+00	767.00
IUUC-Vda-130014	Verticillium dahliae	36.05	4.00e-51	195.00
IUUC-Vpa-130782	Vicugna pacos	94.96	0.00e+00	792.00
IUUC-Vvi-131494	Vitis vinifera	34.65	1.00e-43	170.00
IUUC-Xtr-132165	Xenopus tropicalis	77.84	0.00e+00	629.00
IUUC-Xma-133205	Xiphophorus maculatus	67.83	3.00e-167	581.00
IUUC-Yli-134614	Yarrowia lipolytica	32.86	9.00e-60	224.00
IUUC-Zma-135861	Zea mays	34.15	3.00e-60	225.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence