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Tag Content
UUCD2 ID IUUC-Aml-002278
UUCD1 version UUC-AiM-00573
Ensembl Protein ID ENSAMEP00000012279.1
UniProt Accession G1LYX2; G1LYX2_AILME
Genbank Protein ID ENSAMEP00000012279
Protein Name Uncharacterized protein
Genbank Nucleotide ID ACTA01115832
Gene Name CUL3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000011641.1 ENSAMET00000012802.1 ENSAMEP00000012279.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 8.30e-230 764.7 56 688
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 2    lreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeqlLktynreWekfreqlkvlrkifay 89
           l++a+++i+r++++  ++eely+++y+++l+k+g+klY+ l+ev++e++ ++v+++v +s ++++L+t+n++W++++++++++r+i++y
   Q: 56   LKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLiNKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMY 144
           799*********************************************99*************************************** PP
   S: 90   ldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleat 176
           +dr+yv++ ++v++v++L+l ++r+++v++  i+++l ++ll++i++eRkge+vdr  +++++++l+ L+l+ +++y+e+FEa+fle++
   Q: 145  MDRVYVQQ-NNVENVYNLGLIIFRDQVVRYgcIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMS 232
           ********.******************************************************************************** PP
   S: 177  qefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll....aelvallrdkktedlsrmykL 261
           +ef+++es++fl+en+ + Y+kkvear+nee er++++l++ste+++++vve+eli+kh+++++    ++lv++l++ ktedl++mykL
   Q: 233  AEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVemenSGLVHMLKNGKTEDLACMYKL 321
           ****************************************************************99999******************** PP
   S: 262  lsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaakspE 350
           +srv+ngl++++++++s+++eqgka++++e + k+p++y++ ll+lk++++++++e+Fnnd+ F ++++ +fe+f+n n     ++spE
   Q: 322  FSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLN-----SRSPE 405
           *******************************************************************************.....***** PP
   S: 351  llAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfq 439
           +l+ +iD++L+k++kglte+e+e++ldk++++f++++ekdvFe+yYk+hLa+RLl++ks+s+++E+++i+kLk+ecg++ftskLe+Mf+
   Q: 406  YLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFR 494
           ***************************************************************************************** PP
   S: 440  dlkvSedlnrqFkeekentees.esvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkael. 526
           d+++S++++++F+++ ++t  s  +v+l+v+vL++g+Wpt+s+t+k+++P+  ++++e+f++fYl khsgR+L++qh++g+a+l+a++ 
   Q: 495  DMSISNTTMDEFRQHLQATGVSlGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFy 583
           ********************99889**************************************************************** PP
   S: 527  .........................kkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk..kqvlkkepe 588
                                    +++k++lqVstfQm++L++fnn+ek+++ee++++t++pe+eL r+lqsL+++k  ++vl+kep+
   Q: 584  gpvkkkmkqedgsevgvggaqvtgsNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKptQRVLTKEPK 672
           *************999999998888888************************************************************* PP
   S: 589  skeieeedlfsvNqef 604
           skeie++++f+vN++f
   Q: 673  SKEIENGHIFTVNDQF 688
           **************99 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
HRRLGVRPEA AAGEGTSTMS NLSKGTGSRK DTKMRIRTYP LMTMDEKYVN SIWDLLKNAI 60
QEIQRKNNSG LSFEELYRNA YTMVLHKHGE KLYTGLREVV TEHLINKVRE DVLNSLNNNF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-002278|E3,Cullin|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CACCGGCGCC TCGGAGTGCG ACCCGAAGCC GCCGCCGGGG AGGGGACGAG CACCATGTCG 60
AATCTGAGCA AAGGCACGGG CAGCCGGAAG GACACCAAGA TGCGGATCCG GGNNNNNNNN 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-002278|E3,Cullin|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0070062--C:extracellular exosome
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0016477--P:cell migration
GO:0048208--P:COPII vesicle coating
GO:0040016--P:embryonic cleavage
GO:0044346--P:fibroblast apoptotic process
GO:0007369--P:gastrulation
GO:0007229--P:integrin-mediated signaling pathway
GO:0072576--P:liver morphogenesis
GO:0007080--P:mitotic metaphase plate congression
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032467--P:positive regulation of cytokinesis
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0017145--P:stem cell division
GO:0043149--P:stress fiber assembly
GO:0001831--P:trophectodermal cellular morphogenesis
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome
GO:0016055--P:Wnt signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000335 Aegilops tauschii 46.84 0.00e+00 685.00
IUUC-Atr-002616 Amborella trichopoda 52.93 0.00e+00 770.00
IUUC-Apl-004172 Anas platyrhynchos 99.33 0.00e+00 1517.00
IUUC-Aca-004309 Anolis carolinensis 98.97 0.00e+00 1554.00
IUUC-Aly-005566 Arabidopsis lyrata 51.93 0.00e+00 767.00
IUUC-Ath-007587 Arabidopsis thaliana 52.33 0.00e+00 771.00
IUUC-Ago-007795 Ashbya gossypii 25.13 2.00e-47 184.00
IUUC-Acl-008317 Aspergillus clavatus 36.70 9.00e-145 507.00
IUUC-Afl-008727 Aspergillus flavus 36.35 3.00e-144 505.00
IUUC-Afu-008879 Aspergillus fumigatus 37.76 2.00e-132 466.00
IUUC-Ani-009393 Aspergillus nidulans 35.81 4.00e-135 475.00
IUUC-Ang-009626 Aspergillus niger 36.26 5.00e-141 494.00
IUUC-Aor-010207 Aspergillus oryzae 36.35 4.00e-144 505.00
IUUC-Ate-010305 Aspergillus terreus 36.98 2.00e-140 493.00
IUUC-Ame-011805 Astyanax mexicanus 95.99 0.00e+00 1504.00
IUUC-Bgr-012098 Blumeria graminis 35.72 3.00e-120 426.00
IUUC-Bta-013445 Bos taurus 99.09 0.00e+00 1556.00
IUUC-Bci-013612 Botrytis cinerea 36.43 9.00e-139 487.00
IUUC-Bdi-014269 Brachypodium distachyon 52.02 0.00e+00 743.00
IUUC-Bol-015350 Brassica oleracea 52.46 0.00e+00 769.00
IUUC-Bra-016763 Brassica rapa 52.60 0.00e+00 771.00
IUUC-Cel-018641 Caenorhabditis elegans 48.34 0.00e+00 731.00
IUUC-Cja-019175 Callithrix jacchus 98.97 0.00e+00 1553.00
IUUC-Cfa-020905 Canis familiaris 99.47 0.00e+00 1518.00
IUUC-Cpo-021293 Cavia porcellus 97.15 0.00e+00 1521.00
IUUC-Cre-022776 Chlamydomonas reinhardtii 48.34 0.00e+00 695.00
IUUC-Csa-023800 Chlorocebus sabaeus 98.84 0.00e+00 1550.00
IUUC-Cho-024839 Choloepus hoffmanni 98.39 0.00e+00 1350.00
IUUC-Cin-025201 Ciona intestinalis 70.79 0.00e+00 1022.00
IUUC-Csv-026107 Ciona savignyi 71.01 0.00e+00 1092.00
IUUC-Cgl-026630 Colletotrichum gloeosporioides 35.38 3.00e-124 439.00
IUUC-Cne-027048 Cryptococcus neoformans 34.47 3.00e-117 416.00
IUUC-Cme-027254 Cyanidioschyzon merolae 30.70 1.00e-88 320.00
IUUC-Dre-028488 Danio rerio 96.64 0.00e+00 1519.00
IUUC-Dno-029784 Dasypus novemcinctus 98.97 0.00e+00 1553.00
IUUC-Dor-030682 Dipodomys ordii 92.13 0.00e+00 1363.00
IUUC-Dse-031326 Dothistroma septosporum 35.51 5.00e-128 451.00
IUUC-Dme-032112 Drosophila melanogaster 68.61 0.00e+00 1078.00
IUUC-Ete-032347 Echinops telfairi 80.93 0.00e+00 1193.00
IUUC-Eca-033560 Equus caballus 99.33 0.00e+00 1518.00
IUUC-Eeu-034502 Erinaceus europaeus 97.37 0.00e+00 1342.00
IUUC-Fca-035544 Felis catus 99.47 0.00e+00 1518.00
IUUC-Fal-036751 Ficedula albicollis 99.47 0.00e+00 1518.00
IUUC-Fox-037857 Fusarium oxysporum 36.74 3.00e-137 482.00
IUUC-Fso-038163 Fusarium solani 36.57 7.00e-141 494.00
IUUC-Gmo-039270 Gadus morhua 96.02 0.00e+00 1518.00
IUUC-Ggr-039999 Gaeumannomyces graminis 33.72 2.00e-127 450.00
IUUC-Gga-040329 Gallus gallus 98.97 0.00e+00 1555.00
IUUC-Gac-041510 Gasterosteus aculeatus 95.77 0.00e+00 1514.00
IUUC-Gma-043182 Glycine max 52.65 0.00e+00 746.00
IUUC-Ggo-044903 Gorilla gorilla 99.07 0.00e+00 1509.00
IUUC-Hsa-046000 Homo sapiens 98.84 0.00e+00 1550.00
IUUC-Hvu-047831 Hordeum vulgare 52.17 0.00e+00 699.00
IUUC-Itr-049067 Ictidomys tridecemlineatus 99.12 0.00e+00 936.00
IUUC-Kpa-049372 Komagataella pastoris 34.89 4.00e-115 409.00
IUUC-Lch-050458 Latimeria chalumnae 96.88 0.00e+00 1514.00
IUUC-Lpe-051396 Leersia perrieri 52.34 0.00e+00 755.00
IUUC-Loc-052186 Lepisosteus oculatus 97.93 0.00e+00 1542.00
IUUC-Lma-053030 Leptosphaeria maculans 38.48 2.00e-144 506.00
IUUC-Laf-053684 Loxodonta africana 99.47 0.00e+00 1518.00
IUUC-Mcc-055770 Macaca mulatta 98.84 0.00e+00 1550.00
IUUC-Meu-056852 Macropus eugenii 98.92 0.00e+00 758.00
IUUC-Mor-057273 Magnaporthe oryzae 34.59 1.00e-132 467.00
IUUC-Mpo-057403 Magnaporthe poae 33.96 5.00e-129 455.00
IUUC-Mtr-058317 Medicago truncatula 51.93 0.00e+00 751.00
IUUC-Mla-059055 Melampsora laricipopulina 37.22 5.00e-133 468.00
IUUC-Mga-060076 Meleagris gallopavo 97.73 0.00e+00 1485.00
IUUC-Mvi-060470 Microbotryum violaceum 33.15 1.00e-135 477.00
IUUC-Mmr-060976 Microcebus murinus 99.09 0.00e+00 1556.00
IUUC-Mdo-062741 Monodelphis domestica 99.09 0.00e+00 1556.00
IUUC-Mmu-063905 Mus musculus 98.84 0.00e+00 1551.00
IUUC-Mac-064718 Musa acuminata 51.20 0.00e+00 728.00
IUUC-Mpu-066356 Mustela putorius furo 99.47 0.00e+00 1518.00
IUUC-Mlu-067768 Myotis lucifugus 100.00 0.00e+00 1532.00
IUUC-Nfi-068285 Neosartorya fischeri 37.01 3.00e-146 512.00
IUUC-Ncr-068883 Neurospora crassa 36.08 1.00e-138 486.00
IUUC-Nle-069638 Nomascus leucogenys 99.20 0.00e+00 1513.00
IUUC-Opr-070333 Ochotona princeps 99.63 0.00e+00 1106.00
IUUC-Ont-071601 Oreochromis niloticus 97.15 0.00e+00 1562.00
IUUC-Oan-073281 Ornithorhynchus anatinus 99.21 0.00e+00 1299.00
IUUC-Ocu-074504 Oryctolagus cuniculus 99.47 0.00e+00 1517.00
IUUC-Oba-075332 Oryza barthii 51.90 0.00e+00 747.00
IUUC-Obr-076435 Oryza brachyantha 52.82 0.00e+00 714.00
IUUC-Ogl-077655 Oryza glaberrima 51.89 0.00e+00 756.00
IUUC-Ogu-078458 Oryza glumaepatula 51.90 0.00e+00 747.00
IUUC-Oin-079567 Oryza indica 51.76 0.00e+00 754.00
IUUC-Olo-080930 Oryza longistaminata 52.74 0.00e+00 757.00
IUUC-Ome-081353 Oryza meridionalis 51.89 0.00e+00 756.00
IUUC-Oni-082378 Oryza nivara 51.89 0.00e+00 756.00
IUUC-Opu-084055 Oryza punctata 52.74 0.00e+00 757.00
IUUC-Oru-084202 Oryza rufipogon 51.90 0.00e+00 747.00
IUUC-Osa-085290 Oryza sativa 51.89 0.00e+00 757.00
IUUC-Ola-087562 Oryzias latipes 96.77 0.00e+00 1528.00
IUUC-Olu-087866 Ostreococcus lucimarinus 37.59 4.00e-139 488.00
IUUC-Oga-088833 Otolemur garnettii 99.47 0.00e+00 1518.00
IUUC-Oar-089958 Ovis aries 99.47 0.00e+00 1518.00
IUUC-Ptr-091013 Pan troglodytes 98.84 0.00e+00 1550.00
IUUC-Pan-091796 Papio anubis 99.47 0.00e+00 1520.00
IUUC-Psi-093564 Pelodiscus sinensis 97.73 0.00e+00 1482.00
IUUC-Pno-094939 Phaeosphaeria nodorum 38.04 1.00e-138 487.00
IUUC-Ppa-095920 Physcomitrella patens 52.40 0.00e+00 764.00
IUUC-Pfo-097498 Poecilia formosa 92.81 0.00e+00 1509.00
IUUC-Pab-098164 Pongo abelii 98.84 0.00e+00 1550.00
IUUC-Pop-099497 Populus trichocarpa 53.53 0.00e+00 786.00
IUUC-Pca-100702 Procavia capensis 90.94 0.00e+00 1382.00
IUUC-Ppe-101971 Prunus persica 52.13 0.00e+00 734.00
IUUC-Pva-103129 Pteropus vampyrus 98.97 0.00e+00 1555.00
IUUC-Pgr-103684 Puccinia graminis 36.24 3.00e-110 392.00
IUUC-Ptt-103961 Puccinia triticina 36.42 2.00e-109 390.00
IUUC-Pte-104325 Pyrenophora teres 38.00 3.00e-136 479.00
IUUC-Pyt-104746 Pyrenophora triticirepentis 37.03 3.00e-134 472.00
IUUC-Rno-105935 Rattus norvegicus 99.33 0.00e+00 1516.00
IUUC-Sce-106354 Saccharomyces cerevisiae 26.45 1.00e-52 201.00
IUUC-Sha-106569 Sarcophilus harrisii 98.84 0.00e+00 1380.00
IUUC-Sja-107676 Schizosaccharomyces japonicus 38.55 5.00e-154 538.00
IUUC-Spo-108135 Schizosaccharomyces pombe 36.98 4.00e-138 485.00
IUUC-Smo-109555 Selaginella moellendorffii 53.20 0.00e+00 787.00
IUUC-Sit-110763 Setaria italica 52.41 0.00e+00 759.00
IUUC-Sly-111090 Solanum lycopersicum 52.06 0.00e+00 762.00
IUUC-Stu-112351 Solanum tuberosum 52.20 0.00e+00 764.00
IUUC-Sar-113144 Sorex araneus 100.00 0.00e+00 1120.00
IUUC-Sbi-114690 Sorghum bicolor 52.60 0.00e+00 759.00
IUUC-Sre-115005 Sporisorium reilianum 37.83 5.00e-135 475.00
IUUC-Ssc-116053 Sus scrofa 99.10 0.00e+00 1138.00
IUUC-Tgu-116523 Taeniopygia guttata 99.47 0.00e+00 1518.00
IUUC-Tru-118189 Takifugu rubripes 92.90 0.00e+00 1434.00
IUUC-Tsy-118962 Tarsius syrichta 93.17 0.00e+00 1387.00
IUUC-Tni-120614 Tetraodon nigroviridis 57.31 0.00e+00 869.00
IUUC-Tca-121282 Theobroma cacao 52.99 0.00e+00 767.00
IUUC-Tre-122201 Trichoderma reesei 35.72 1.00e-133 470.00
IUUC-Tvi-122321 Trichoderma virens 36.33 3.00e-134 472.00
IUUC-Tae-124292 Triticum aestivum 52.34 0.00e+00 738.00
IUUC-Tur-126800 Triticum urartu 52.20 0.00e+00 737.00
IUUC-Tme-127053 Tuber melanosporum 40.26 3.00e-156 545.00
IUUC-Tbe-127427 Tupaia belangeri 84.72 0.00e+00 1160.00
IUUC-Ttr-128662 Tursiops truncatus 97.60 0.00e+00 1476.00
IUUC-Uma-129597 Ustilago maydis 38.32 2.00e-134 473.00
IUUC-Vda-129726 Verticillium dahliae 35.21 2.00e-133 470.00
IUUC-Vpa-130809 Vicugna pacos 100.00 0.00e+00 746.00
IUUC-Vvi-131194 Vitis vinifera 52.59 0.00e+00 760.00
IUUC-Xtr-131887 Xenopus tropicalis 97.81 0.00e+00 1535.00
IUUC-Xma-133517 Xiphophorus maculatus 97.02 0.00e+00 1528.00
IUUC-Yli-134576 Yarrowia lipolytica 33.67 2.00e-111 396.00
IUUC-Zma-135030 Zea mays 53.00 0.00e+00 766.00
Created Date 25-Jun-2017

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