iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000004544.7	ENSRNOT00000006429.7	ENSRNOP00000006429.6
ENSRNOG00000004544.7	ENSRNOT00000079672.1	ENSRNOP00000074875.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
miRNAMap	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.30e-50	169.5	59	194

Active Site

Position(s)	Description	Evidence
139	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel+e++ dpp+++sa+p+ + +++ew+ +ilGp++++YeggvF l+i+f++dYPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 59   RIQKELAEITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 144
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 145  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQ 194
           ********************************************999875 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MMRALAPAVV VQMQTSETLP LQSLRNRKKE NLLPPSRRKT PNSLAKRLLS YPLVLKANRI 60
QKELAEITLD PPPNCSAGPK GDNIYEWRST ILGPPGSVYE GGVFFLDITF SSDYPFKPPK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGCTGACT GCGCGACCGG GAGGAGCCGA GCCGAGCCGA GCGGGGCGGC GGGAGGCTGA 60
GCGCGCGGGG GGCTCCCGCG TCCCTGCGCC TCGGCCGGCG GAGCGCCCAC CCCACCGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003415	Anas platyrhynchos	100.00	2.00e-84	304.00
IUUC-Aca-005276	Anolis carolinensis	100.00	1.00e-84	305.00
IUUC-Ame-011419	Astyanax mexicanus	96.50	1.00e-81	295.00
IUUC-Bta-012796	Bos taurus	97.90	4.00e-81	293.00
IUUC-Cja-019670	Callithrix jacchus	100.00	2.00e-84	304.00
IUUC-Cfa-021171	Canis familiaris	100.00	2.00e-84	304.00
IUUC-Csa-023464	Chlorocebus sabaeus	100.00	2.00e-84	304.00
IUUC-Dre-027376	Danio rerio	100.00	2.00e-83	301.00
IUUC-Eca-033312	Equus caballus	100.00	2.00e-84	304.00
IUUC-Eeu-035232	Erinaceus europaeus	100.00	2.00e-83	300.00
IUUC-Fal-036688	Ficedula albicollis	100.00	2.00e-84	304.00
IUUC-Gga-040613	Gallus gallus	100.00	2.00e-84	304.00
IUUC-Hsa-046464	Homo sapiens	100.00	2.00e-84	304.00
IUUC-Itr-048624	Ictidomys tridecemlineatus	100.00	1.00e-73	267.00
IUUC-Loc-052492	Lepisosteus oculatus	100.00	2.00e-84	305.00
IUUC-Laf-054416	Loxodonta africana	100.00	2.00e-84	304.00
IUUC-Mcc-055754	Macaca mulatta	100.00	2.00e-84	304.00
IUUC-Mtr-058214	Medicago truncatula	60.42	4.00e-52	196.00
IUUC-Mga-059436	Meleagris gallopavo	100.00	2.00e-84	304.00
IUUC-Mmr-060893	Microcebus murinus	99.30	3.00e-84	304.00
IUUC-Mdo-063010	Monodelphis domestica	100.00	2.00e-84	304.00
IUUC-Mmu-063493	Mus musculus	100.00	2.00e-84	304.00
IUUC-Mpu-065789	Mustela putorius furo	100.00	2.00e-84	304.00
IUUC-Mlu-066934	Myotis lucifugus	100.00	2.00e-84	304.00
IUUC-Nle-069930	Nomascus leucogenys	100.00	2.00e-84	304.00
IUUC-Opr-070917	Ochotona princeps	93.81	1.00e-58	217.00
IUUC-Olu-087783	Ostreococcus lucimarinus	78.42	5.00e-65	239.00
IUUC-Oga-088760	Otolemur garnettii	100.00	2.00e-84	304.00
IUUC-Oar-090077	Ovis aries	100.00	2.00e-84	304.00
IUUC-Pan-092142	Papio anubis	100.00	2.00e-84	304.00
IUUC-Psi-093471	Pelodiscus sinensis	100.00	2.00e-84	304.00
IUUC-Pab-098675	Pongo abelii	100.00	2.00e-84	304.00
IUUC-Pop-099024	Populus trichocarpa	64.79	8.00e-57	212.00
IUUC-Pca-100467	Procavia capensis	100.00	2.00e-84	304.00
IUUC-Ppe-101314	Prunus persica	59.03	1.00e-52	198.00
IUUC-Pva-103205	Pteropus vampyrus	100.00	2.00e-84	304.00
IUUC-Smo-108957	Selaginella moellendorffii	69.59	4.00e-61	226.00
IUUC-Sly-111200	Solanum lycopersicum	61.27	1.00e-53	202.00
IUUC-Sar-113672	Sorex araneus	100.00	2.00e-84	304.00
IUUC-Tgu-116892	Taeniopygia guttata	100.00	2.00e-84	304.00
IUUC-Tru-118527	Takifugu rubripes	96.48	1.00e-80	291.00
IUUC-Tsy-119046	Tarsius syrichta	100.00	5.00e-84	303.00
IUUC-Tca-121777	Theobroma cacao	62.94	8.00e-55	206.00
IUUC-Tbe-127690	Tupaia belangeri	100.00	4.00e-84	303.00
IUUC-Ttr-128849	Tursiops truncatus	100.00	2.00e-84	304.00
IUUC-Vvi-131190	Vitis vinifera	62.50	9.00e-54	202.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence