iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037593

Ensembl Protein ID

ENSFALP00000014115.1

UniProt Accession

U3KGG1; U3KGG1_FICAL

Genbank Protein ID

ENSFALP00000014115

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01001340

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000013524.1	ENSFALT00000014173.1	ENSFALP00000014115.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-32	109.5	361	400
UBD/Beta-Prp	1.10e-63	214.9	271	560

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 361  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 400
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           +++++h++ +++v+fsp+++llatg++d+++k+w+v    +    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   htl
   Q: 271  CVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVLGDRCepKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDNRLRHTL 359
           7899**********************************999999********************************************* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           +gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd++t++++++l+   
   Q: 360  TGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRTESIVKELE--L 442
           ****************************************9999988....888888889*************************6..6 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
            ++++ l+++++++el+++s+d  +k+ dl+ + + +t+ ++     +  ++v fsp++++++ gs+Dg ++iW++ +g+l +tl++h+
   Q: 443  FGRITALDLNPERTELLTCSRDDLLKIIDLRVSAVKQTFSAQGfkcgSDWTRVVFSPDGNYVAAGSADGALYIWNVLTGKLERTLAKHH 531
           9******************************88887777777777776666799*********************************** PP
   S: 265  ssvisvavlsfgdnvlvlgsedskvniwk 293
           ss+i   ++s+ + ++v++++ +k+ +w+
   Q: 532  SSSINAVTWSPAGAHVVSVDKGNKAVLWS 560
           *********************99999996 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MQSRHEISPG HDGTWNDAQL QELAQLKIKH QEELTELHKK RGELAQSVID LNNQMQQKDK 60
EMQMNEAKIA EYLQRISELE TECQELRSKL QDLERANQTL KDEYDALQIT FNALEEKLRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC 60
CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCGAGGAGCT GCGGCGGCGG GATCGACTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR012284--6PGD_dom_3
IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0039689--P:negative stranded viral RNA replication

KEGG

fab:101809920

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	27.87	1.00e-31	130.00
IUUC-Aml-002242	Ailuropoda melanoleuca	80.74	0.00e+00	920.00
IUUC-Atr-003073	Amborella trichopoda	28.14	2.00e-28	120.00
IUUC-Apl-003384	Anas platyrhynchos	95.37	0.00e+00	1100.00
IUUC-Aca-004962	Anolis carolinensis	90.04	0.00e+00	1014.00
IUUC-Aly-005435	Arabidopsis lyrata	34.32	1.00e-45	177.00
IUUC-Ath-006948	Arabidopsis thaliana	34.32	3.00e-46	179.00
IUUC-Ame-010915	Astyanax mexicanus	80.43	6.00e-157	546.00
IUUC-Bta-012388	Bos taurus	88.75	0.00e+00	1025.00
IUUC-Bdi-014231	Brachypodium distachyon	27.86	7.00e-36	144.00
IUUC-Bol-016174	Brassica oleracea	35.31	4.00e-47	182.00
IUUC-Bra-017165	Brassica rapa	34.65	2.00e-46	179.00
IUUC-Cel-018131	Caenorhabditis elegans	37.39	2.00e-60	226.00
IUUC-Cja-018898	Callithrix jacchus	74.43	0.00e+00	812.00
IUUC-Cfa-020484	Canis familiaris	85.59	0.00e+00	981.00
IUUC-Cpo-022156	Cavia porcellus	84.29	0.00e+00	958.00
IUUC-Csa-024019	Chlorocebus sabaeus	82.32	0.00e+00	927.00
IUUC-Cho-024311	Choloepus hoffmanni	72.82	0.00e+00	814.00
IUUC-Cin-025260	Ciona intestinalis	36.56	1.00e-100	360.00
IUUC-Csv-025836	Ciona savignyi	45.67	4.00e-50	190.00
IUUC-Dre-027702	Danio rerio	77.44	0.00e+00	860.00
IUUC-Dno-029728	Dasypus novemcinctus	86.63	0.00e+00	1021.00
IUUC-Dor-030587	Dipodomys ordii	84.55	1.00e-101	363.00
IUUC-Dme-031595	Drosophila melanogaster	41.20	4.00e-110	391.00
IUUC-Ete-032969	Echinops telfairi	68.79	0.00e+00	712.00
IUUC-Eca-034214	Equus caballus	86.05	0.00e+00	882.00
IUUC-Eeu-034537	Erinaceus europaeus	80.56	0.00e+00	841.00
IUUC-Fca-036005	Felis catus	87.74	0.00e+00	987.00
IUUC-Gmo-039042	Gadus morhua	66.11	0.00e+00	649.00
IUUC-Gga-040986	Gallus gallus	97.69	0.00e+00	1106.00
IUUC-Gac-041351	Gasterosteus aculeatus	75.53	0.00e+00	871.00
IUUC-Gma-043452	Glycine max	31.37	1.00e-48	187.00
IUUC-Ggo-045427	Gorilla gorilla	86.27	0.00e+00	975.00
IUUC-Hsa-046632	Homo sapiens	84.46	0.00e+00	962.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	80.28	0.00e+00	910.00
IUUC-Lch-049439	Latimeria chalumnae	48.87	4.00e-131	461.00
IUUC-Lpe-051254	Leersia perrieri	30.13	2.00e-38	153.00
IUUC-Loc-052610	Lepisosteus oculatus	79.04	0.00e+00	895.00
IUUC-Laf-053936	Loxodonta africana	84.19	0.00e+00	972.00
IUUC-Mcc-055504	Macaca mulatta	83.59	0.00e+00	996.00
IUUC-Meu-056516	Macropus eugenii	89.04	0.00e+00	932.00
IUUC-Mtr-058062	Medicago truncatula	32.67	2.00e-44	173.00
IUUC-Mga-059777	Meleagris gallopavo	95.38	0.00e+00	1095.00
IUUC-Mmr-061298	Microcebus murinus	88.08	0.00e+00	996.00
IUUC-Mdo-062969	Monodelphis domestica	88.63	0.00e+00	1023.00
IUUC-Mmu-064076	Mus musculus	85.92	0.00e+00	969.00
IUUC-Mac-065161	Musa acuminata	30.25	1.00e-39	156.00
IUUC-Mpu-066196	Mustela putorius furo	88.08	0.00e+00	996.00
IUUC-Mlu-067651	Myotis lucifugus	84.37	0.00e+00	970.00
IUUC-Nle-069853	Nomascus leucogenys	83.10	0.00e+00	947.00
IUUC-Opr-070350	Ochotona princeps	86.83	6.00e-111	394.00
IUUC-Ont-072489	Oreochromis niloticus	77.80	0.00e+00	859.00
IUUC-Oan-072703	Ornithorhynchus anatinus	83.10	0.00e+00	914.00
IUUC-Ocu-074205	Oryctolagus cuniculus	85.00	0.00e+00	980.00
IUUC-Oba-075619	Oryza barthii	30.53	1.00e-36	147.00
IUUC-Obr-076632	Oryza brachyantha	29.97	1.00e-38	154.00
IUUC-Ogl-077671	Oryza glaberrima	30.53	1.00e-36	147.00
IUUC-Ogu-078052	Oryza glumaepatula	30.53	1.00e-36	147.00
IUUC-Oin-079611	Oryza indica	30.53	6.00e-35	141.00
IUUC-Olo-080408	Oryza longistaminata	30.53	2.00e-36	146.00
IUUC-Ome-081560	Oryza meridionalis	30.53	1.00e-36	147.00
IUUC-Oni-082145	Oryza nivara	30.53	1.00e-36	147.00
IUUC-Opu-083918	Oryza punctata	30.18	5.00e-36	145.00
IUUC-Oru-084858	Oryza rufipogon	30.53	7.00e-35	141.00
IUUC-Osa-086277	Oryza sativa	30.53	5.00e-35	142.00
IUUC-Ola-086816	Oryzias latipes	74.89	4.00e-88	317.00
IUUC-Olu-087622	Ostreococcus lucimarinus	35.33	5.00e-45	174.00
IUUC-Oga-088765	Otolemur garnettii	81.46	0.00e+00	887.00
IUUC-Oar-090196	Ovis aries	86.00	0.00e+00	934.00
IUUC-Ptr-091676	Pan troglodytes	84.64	0.00e+00	964.00
IUUC-Pan-092068	Papio anubis	86.99	0.00e+00	983.00
IUUC-Psi-093367	Pelodiscus sinensis	91.28	0.00e+00	1014.00
IUUC-Ppa-095699	Physcomitrella patens	29.01	5.00e-42	165.00
IUUC-Pfo-096067	Poecilia formosa	74.95	0.00e+00	830.00
IUUC-Pab-098111	Pongo abelii	86.27	0.00e+00	976.00
IUUC-Pop-099116	Populus trichocarpa	33.88	1.00e-44	174.00
IUUC-Pca-100680	Procavia capensis	76.69	0.00e+00	799.00
IUUC-Ppe-101790	Prunus persica	32.45	2.00e-45	176.00
IUUC-Pva-102871	Pteropus vampyrus	84.04	0.00e+00	967.00
IUUC-Rno-106088	Rattus norvegicus	85.51	0.00e+00	960.00
IUUC-Sha-106984	Sarcophilus harrisii	86.50	0.00e+00	1014.00
IUUC-Smo-109404	Selaginella moellendorffii	33.11	8.00e-43	167.00
IUUC-Sit-110828	Setaria italica	31.83	5.00e-40	158.00
IUUC-Sly-111009	Solanum lycopersicum	31.50	2.00e-46	180.00
IUUC-Stu-112370	Solanum tuberosum	32.02	2.00e-47	183.00
IUUC-Sar-113659	Sorex araneus	57.51	3.00e-84	304.00
IUUC-Sbi-114819	Sorghum bicolor	30.62	6.00e-39	155.00
IUUC-Ssc-116241	Sus scrofa	83.85	0.00e+00	951.00
IUUC-Tgu-116576	Taeniopygia guttata	95.55	0.00e+00	1097.00
IUUC-Tru-118336	Takifugu rubripes	66.79	0.00e+00	721.00
IUUC-Tsy-119006	Tarsius syrichta	83.99	0.00e+00	936.00
IUUC-Tni-120300	Tetraodon nigroviridis	75.00	0.00e+00	828.00
IUUC-Tca-121002	Theobroma cacao	35.47	9.00e-49	187.00
IUUC-Tae-124868	Triticum aestivum	28.52	2.00e-32	133.00
IUUC-Tur-126463	Triticum urartu	27.87	6.00e-32	132.00
IUUC-Tbe-127631	Tupaia belangeri	85.40	0.00e+00	850.00
IUUC-Ttr-129005	Tursiops truncatus	78.02	1.00e-153	536.00
IUUC-Vpa-130246	Vicugna pacos	79.33	0.00e+00	724.00
IUUC-Vvi-130878	Vitis vinifera	35.24	2.00e-46	179.00
IUUC-Xtr-132798	Xenopus tropicalis	72.79	0.00e+00	806.00
IUUC-Xma-133264	Xiphophorus maculatus	74.59	0.00e+00	825.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence