iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011319

Ensembl Protein ID

ENSAMXP00000009461.1

UniProt Accession

W5KPE9; W5KPE9_ASTMX

Genbank Protein ID

ENSAMXP00000009461

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01098532

Gene Name

EML6 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000009201.1	ENSAMXT00000009461.1	ENSAMXP00000009461.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-38	128.4	1559	1590
UBD/Beta-Prp	8.80e-99	330.7	595	813

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           ++++la  +  + ++++sdDgti++WDl + +
   Q: 1559 EIWGLAThPAkDVFITASDDGTIRIWDLVDKK 1590
           56666656445789*************98766 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ i+ ++++p k++ atg  +rd  + vwdv++ k+l+ l   h+ +v a++fs dgk lv+++ D  +ti vwd ++g+ + t 
   Q: 595  GHDDDIIS-LTVHPIKDYAATGqvGRDPAVHVWDVQSLKCLSLLrGFHQRGVCALDFSADGKSLVSVGVDdnHTIIVWDWKKGEKLATA 682
           67777777.99**********95569******************666******************99999899**************** PP
   S: 91   kghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++  ++ sp   dklv+ +  + ir w+l  g    +     + g+ ++ ++v++    +l++sG++++ + +W  k  +ll+t
   Q: 683  RGHKDKLFVVKCSPfLMDKLVTVG-MKHIRFWQLAGGGLTFKrgvfGNLGRPETMMSVCFGHAHDLVFSGAANGDIYIW--KEPTLLKT 768
           **************5559999988.99*******99887777799888899999********99***************..88****** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
            +  h+++v  +   +  k +v+g++dg v+lwd   ++c++t+   +
   Q: 769  IKA-HDGPVFAMFSLE--KGFVTGGKDGVVELWDDTFERCLKTYAIKR 813
           *98.*****9997666..68**********************997666 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

QRLVSVGLDA KNTVCVWDWK RGKVIATATG HSDRIFDITW DPFQQNRMVS CGVKHIKFWS 60
MCGNALTPKR GIFGKTGDLQ TILCVSAAKD EITYSGALNG DIYVWKGLNL IRTVQGAHGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAGGTTGG TGTCTGTGGG TTTGGATGCT AAAAATACGG TGTGTGTTTG GGACTGGAAA 60
CGAGGCAAAG TCATCGCTAC TGCAACCGGC CACTCGGACA GGGTGAGGAC CTGCTTTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011044--Quino_amine_DH_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-025038	Choloepus hoffmanni	80.50	0.00e+00	1258.00
IUUC-Lch-050345	Latimeria chalumnae	78.73	0.00e+00	2335.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence