iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132281

Ensembl Protein ID

ENSXETP00000033200.3

UniProt Accession

F7AML5; F7AML5_XENTR

Genbank Protein ID

ENSXETP00000033200

Protein Name

Echinoderm microtubule-associated protein-like 6

Genbank Nucleotide ID

AAMC01063883

Gene Name

eml6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000015159.3	ENSXETT00000033200.3	ENSXETP00000033200.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-21	75.0	324	355
UBD/Beta-Prp	1.70e-54	185.2	318	590

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           ++v++la  +  +l ++ sdD+t+++W+l+++
   Q: 324  GEVWGLAThPQlPLCATVSDDKTLRIWELSSQ 355
           46888887888899**************9775 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++gh+++ +  ++ +p+ +l+at s+d+t+++w+++++  +  + + +++ +++ fspdgk l+ g +D+   v + +t + +++++  
   Q: 318  VQGHMEGEVWGLATHPQLPLCATVSDDKTLRIWELSSQHRMLAVRKLKKGGRCCAFSPDGKALAVGLSDGSFLVVNADTLEDMVSFHHR 406
           78999999999*****************************99999999999******************888888************88 PP
   S: 94   edsvlslsfsp.sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl............... 166
           ++ + +++fsp  g++l+++shd+ + ++++ + + +  + +g ++ ++++ ++  g+ll   s  +   ++                 
   Q: 407  KEIIADIKFSPdAGKYLAVASHDNFVDIYNVLSSKRVG-ICKGASSYITHIDWDTRGKLLQVNSGAKEQLFYEAprgkrytnlsemeki 494
           888899*****666***********************9.******************88877777777777999555555555544444 PP
   S: 167  ...ktgkllrtl..............tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec...vrtlnghtdnvksvrfs.pnd 234
                      +               + +  +v+  s+++++k l++g++ g vkl+++  + c    +++ gh++ v+ vr + +++
   Q: 495  ewhT-------WtcvlgptcegiwpaHS-DITDVNAASLTKDRKALATGDDFGFVKLFSYPVKGCdakFKKYVGHSAHVTNVRWLyDDS 575
           4440.......14444444444446443.67777777799999******************88888889***************98888 PP
   S: 235  erlvsgssDgsiriW 249
           ++l +g++D  + iW
   Q: 576  TLLTVGGADTALMIW 590
           8899999******** PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

PDESLKLKFV HGYRGYDCRN NLFYTQAGEV VYHVAAIAVV YDRLQHSQRF YLGHDDDILS 60
LAIHPVKDYV ATGQNRANSC RDCPTQPLNI RVWDTQTLKC LSLLKGQHQR GVSALDFSAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGACGAGA GTCTAAAGCT AAAATTTGTA CATGGGTAAC TATGCAATTA ATATTTTCCT 60
TTTTCTACAT CATTCACAAC AAACCCTTCC CCAGTGAAGG TTACAGTCTA AGGCCCCTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dor-030880	Dipodomys ordii	64.74	0.00e+00	717.00
IUUC-Olu-087860	Ostreococcus lucimarinus	39.14	4.00e-117	415.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence