iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-123984

Ensembl Protein ID

TRIAE_CS42_3AS_TGACv1_213656_AA0707610.1

UniProt Accession

A0A1D5VMN1; A0A1D5VMN1_WHEAT

Protein Name

Presenilin

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_3AS_TGACv1_213656_AA0707610	TRIAE_CS42_3AS_TGACv1_213656_AA0707610.1	TRIAE_CS42_3AS_TGACv1_213656_AA0707610.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	33.44	6.00e-23	106.00	IUUC-Dre-028689

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Triticum aestivum

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MDPVADGPDP PGSAATVLDT LGEEVLAVMS PVSICMALVV LLITLLAPPS SSPSAPPPVT 60
AATLVYLESP SDSPAQKLVG ALLDAAVFVA LVAVVTFILV ALYYYRCTGF LKNYMRFSAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGCACAGG AACACGAGTT TTGCAGGGAA CGCGTGAGAG TGAGTCGAAC TGAAAGGGAC 60
ACCCACCACC AAACCCTCCG TGCGAGACCG ACCGCCGCAG GGAGCGAGCG ACCCAGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	98.00	0.00e+00	640.00
IUUC-Aml-001648	Ailuropoda melanoleuca	34.09	2.00e-31	130.00
IUUC-Atr-003039	Amborella trichopoda	53.68	1.00e-109	390.00
IUUC-Aca-004582	Anolis carolinensis	31.80	2.00e-32	134.00
IUUC-Ath-006730	Arabidopsis thaliana	57.89	4.00e-58	219.00
IUUC-Ame-010686	Astyanax mexicanus	31.49	2.00e-29	123.00
IUUC-Bol-015841	Brassica oleracea	57.21	3.00e-53	203.00
IUUC-Cin-025780	Ciona intestinalis	31.74	1.00e-39	157.00
IUUC-Dre-028689	Danio rerio	29.91	2.00e-27	117.00
IUUC-Dor-030609	Dipodomys ordii	54.32	2.00e-18	87.40
IUUC-Gga-040993	Gallus gallus	31.80	8.00e-34	138.00
IUUC-Hvu-047141	Hordeum vulgare	96.96	0.00e+00	664.00
IUUC-Lpe-051132	Leersia perrieri	73.73	1.00e-130	460.00
IUUC-Mac-064858	Musa acuminata	93.18	6.00e-43	168.00
IUUC-Ont-071846	Oreochromis niloticus	30.57	5.00e-30	125.00
IUUC-Oan-072783	Ornithorhynchus anatinus	35.19	2.00e-30	127.00
IUUC-Ogl-077097	Oryza glaberrima	75.00	4.00e-131	462.00
IUUC-Ome-081814	Oryza meridionalis	78.17	2.00e-135	476.00
IUUC-Opu-084176	Oryza punctata	79.35	2.00e-129	456.00
IUUC-Oru-084618	Oryza rufipogon	76.56	4.00e-126	445.00
IUUC-Olu-087811	Ostreococcus lucimarinus	42.72	9.00e-41	161.00
IUUC-Psi-093505	Pelodiscus sinensis	31.34	1.00e-32	134.00
IUUC-Pfo-097396	Poecilia formosa	31.38	9.00e-37	148.00
IUUC-Pop-099661	Populus trichocarpa	53.54	2.00e-49	190.00
IUUC-Sha-107045	Sarcophilus harrisii	31.19	3.00e-31	130.00
IUUC-Smo-109325	Selaginella moellendorffii	49.12	5.00e-37	149.00
IUUC-Sly-110865	Solanum lycopersicum	88.57	9.00e-33	132.00
IUUC-Sar-113169	Sorex araneus	42.06	5.00e-19	89.40
IUUC-Tgu-116469	Taeniopygia guttata	32.58	1.00e-30	127.00
IUUC-Tca-121865	Theobroma cacao	66.84	3.00e-58	219.00
IUUC-Tur-126237	Triticum urartu	99.44	2.00e-167	582.00
IUUC-Vvi-131312	Vitis vinifera	52.93	6.00e-100	358.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence