iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125395

Ensembl Protein ID

TRIAE_CS42_U_TGACv1_641043_AA2083140.1

UniProt Accession

A0A1D6D922; A0A1D6D922_WHEAT

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_U_TGACv1_641043_AA2083140	TRIAE_CS42_U_TGACv1_641043_AA2083140.1	TRIAE_CS42_U_TGACv1_641043_AA2083140.1
TRIAE_CS42_U_TGACv1_641043_AA2083140	TRIAE_CS42_U_TGACv1_641043_AA2083140.3	TRIAE_CS42_U_TGACv1_641043_AA2083140.3
TRIAE_CS42_U_TGACv1_641043_AA2083140	TRIAE_CS42_U_TGACv1_641043_AA2083140.4	TRIAE_CS42_U_TGACv1_641043_AA2083140.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-33	115.0	183	224
UBD/Beta-Prp	1.20e-66	227.6	10	296

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 183  GHQKGVNCVDYftgGDrPYLITGSDDSTAKVWDYQTKSCVQT 224
           8********966*9778*******************999986 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrt 75
            ++++++++++v+ +p +++++++ ++gt+ +wd++t+++++s++  e +v++ kf +++++ v g++D++
   Q: 10   KFAQRSERVKSVDLHPTEPWILASLYSGTLCIWDYQTQTMVKSFEVSELPVRSAKFVSRKQWVVAGADDMF 80
           567788999************************************************************** PP
   S: 76   ikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvh 146
           i+v++++t + + ++++h+d++++++++p+  +++s s+d  i++wd+++g+   ++++gh++ v+ v+++
   Q: 81   IRVYNYNTMDKIKVFEAHTDYIRCVAVHPTLPYVLSSSDDMLIKLWDWDKGWMCTQIFEGHSHYVMQVTFN 151
           ****************************************************9999*************** PP
   S: 147  pdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklwdlqtgec 214
           p++ n ++s+slDrt ++W+l + +   tl g h++ v++++     ++++l++gs+d+t k+wd+qt++c
   Q: 152  PKDtNTFASASLDRTTKIWSLGSPDPNFTLDG-HQKGVNCVDyfTGGDRPYLITGSDDSTAKVWDYQTKSC 221
           *******************************9.*********7445566********************** PP
   S: 215  vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgse 285
           v+tl+ght n++ v f+p+  ++++gs+Dg++riW +++  l +tl++  ++v++v +++   + +v g +
   Q: 222  VQTLEGHTHNISAVCFHPELPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAVGYMKG-SRRMVIGYD 291
           ********************************************************99444.455555555 PP
   S: 286  dskvn 290
           +++++
   Q: 292  EGTIM 296
           56655 PP

Organism

Triticum aestivum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK FAQRSERVKS VDLHPTEPWI LASLYSGTLC IWDYQTQTMV KSFEVSELPV 60
RSAKFVSRKQ WVVAGADDMF IRVYNYNTMD KIKVFEAHTD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAAAATAAA AAAAAATACG CACAAAAACC CCTCCTCCCT CCCCCTCTCC ATCTCTTCTC 60
TCCTCCCACC CCGCTTCGCT CCTCCACCGA GCTCGCGCGA TCCGGCTCGC ACCTCCCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003090	Amborella trichopoda	77.97	0.00e+00	1477.00
IUUC-Acl-008237	Aspergillus clavatus	52.65	0.00e+00	904.00
IUUC-Afl-008535	Aspergillus flavus	53.34	0.00e+00	853.00
IUUC-Aor-009939	Aspergillus oryzae	52.49	0.00e+00	912.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	65.71	0.00e+00	1112.00
IUUC-Cin-025681	Ciona intestinalis	59.20	0.00e+00	988.00
IUUC-Cne-026986	Cryptococcus neoformans	48.67	0.00e+00	852.00
IUUC-Dme-031791	Drosophila melanogaster	57.04	0.00e+00	1008.00
IUUC-Fox-037711	Fusarium oxysporum	52.58	0.00e+00	847.00
IUUC-Gmo-039046	Gadus morhua	62.00	0.00e+00	1089.00
IUUC-Ggr-039863	Gaeumannomyces graminis	52.46	0.00e+00	871.00
IUUC-Kpa-049265	Komagataella pastoris	51.53	0.00e+00	848.00
IUUC-Lma-053218	Leptosphaeria maculans	52.51	0.00e+00	863.00
IUUC-Laf-053757	Loxodonta africana	59.65	0.00e+00	1097.00
IUUC-Mor-057264	Magnaporthe oryzae	52.14	0.00e+00	854.00
IUUC-Mpo-057538	Magnaporthe poae	52.09	0.00e+00	871.00
IUUC-Mvi-060240	Microbotryum violaceum	47.12	0.00e+00	881.00
IUUC-Ogl-077450	Oryza glaberrima	91.66	0.00e+00	1705.00
IUUC-Oni-082324	Oryza nivara	90.87	0.00e+00	1679.00
IUUC-Oru-084829	Oryza rufipogon	90.78	0.00e+00	1680.00
IUUC-Olu-087655	Ostreococcus lucimarinus	65.47	0.00e+00	1139.00
IUUC-Pno-094785	Phaeosphaeria nodorum	59.45	3.00e-103	370.00
IUUC-Ppa-095911	Physcomitrella patens	74.70	0.00e+00	1391.00
IUUC-Pab-097926	Pongo abelii	58.51	0.00e+00	1034.00
IUUC-Pgr-103453	Puccinia graminis	52.20	0.00e+00	890.00
IUUC-Ptt-103868	Puccinia triticina	52.39	0.00e+00	891.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	52.36	0.00e+00	845.00
IUUC-Smo-108695	Selaginella moellendorffii	80.02	0.00e+00	1390.00
IUUC-Sly-111775	Solanum lycopersicum	80.78	0.00e+00	1550.00
IUUC-Stu-112906	Solanum tuberosum	80.20	0.00e+00	1417.00
IUUC-Tre-122072	Trichoderma reesei	51.97	0.00e+00	874.00
IUUC-Tvi-122546	Trichoderma virens	51.72	0.00e+00	857.00
IUUC-Tme-127041	Tuber melanosporum	53.32	0.00e+00	907.00
IUUC-Ttr-129294	Tursiops truncatus	61.02	0.00e+00	1098.00
IUUC-Uma-129351	Ustilago maydis	49.76	0.00e+00	869.00
IUUC-Vda-129716	Verticillium dahliae	52.95	0.00e+00	896.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence