iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108069

UUCD1 version

UUC-ScP-00106

Ensembl Protein ID

SPBC15D4.14.1:pep

UniProt Accession

O74319; TAF73_SCHPO

Genbank Protein ID

CAA20489.1; BAB12572.1

Protein Name

Transcription initiation factor TFIID subunit taf73; Transcription initiation factor TFIID 73 kDa subunit

Genbank Nucleotide ID

CU329671; AB039954

Gene Name

taf73; SPBC15D4.14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC15D4.14	SPBC15D4.14.1	SPBC15D4.14.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.30e-35	115.6	485	522
UBD/Beta-Prp	1.40e-60	203.1	345	636

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH+++v c++f ++  +l++Gs D+t ++WD+rtg  +
   Q: 485  GHQNDVDCVSFhPNaAYLATGSSDHTTRMWDVRTGGTV 522
           8***********999*******************9876 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkl............lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgk 85
           +++  s ++c +fs+d s++a g++d++i +++ t+                +sl gh+ +v  v++sp++++++++seD++ ++w+ +t +
   Q: 345  MHNTLSAVNCAAFSDDASMFALGCADSSIHLYSSTNNGPqplvgsqneplqKSSLIGHTRPVFGVSISPQKEFILSCSEDGFTRLWSKDTKS 436
           566778899**************************9777999********9999************************************** PP
   S: 86   cvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           +++++ gh++ +++++fsp g++++++shd+t+r+wd+e+   l+ ++ gh+  v cv++hp++ +l++Gs D t r+Wd++tg  +r +  
   Q: 437  TIVKYAGHNAPIWDVQFSPFGYYFATASHDQTARLWDVEHAAPLR-VFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGGTVRVFNA 527
           *********************************************.********************************************98 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn..... 264
            h+++v  l ++ +g +l+s+++ g +k+wdl++++  +++  h++ v+s+ fs ++++lvsg++D  +++Wdl+ +++l+  +++      
   Q: 528  -HHSPVSALCMSADGLSLASADESGIIKVWDLRSSNQHVSFVKHSSIVYSLSFSYDNKILVSGGADTDVNFWDLTYRNNLSDGEQSPllfnf 618
           .***********************************************************************77776666555444455555 PP
   S: 265  .ssvisvavlsfgdnvlv 281
            ++ + ++ lsf++++++
   Q: 619  kTKNTIIQNLSFTRRNYC 636
           578888888888855554 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription. Regulates the genes involved in ubiquitin-dependent proteolysis during the progression of M-phase of mitosis.

Protein Sequence
(Fasta)

MAQSSYSSGN STSDLNKIVL DYLFKKGYSR TEAMLRLEIS SVGAIPEEQQ DWHIGASETY 60
VQVYILLRDW IDGTLDLYKP KLQKVLYPIF VHSYLDLLQK NDPEMAIYFF ESFRIEHEVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAAAGTAT TCAAAGTAAT TTATTTACGG AAAGTTGTTC TGCGGCTCAA ACAAAATTCA 60
CTGATCGCTA ATGAAATATG AGGTAAGAGG AAATCACTTA CAAATTTATA ATGTAATTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005669--C:transcription factor TFIID complex
GO:0006355--P:regulation of transcription, DNA-templated
GO:0051123--P:RNA polymerase II transcriptional preinitiation complex assembly
GO:0006367--P:transcription initiation from RNA polymerase II promoter

KEGG

spo:SPBC15D4.14

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Olu-087616	Ostreococcus lucimarinus	32.55	3.00e-81	294.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence