iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000014597.1	ENSONIT00000018386.1	ENSONIP00000018369.1
ENSONIG00000014597.1	ENSONIT00000018387.1	ENSONIP00000018370.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-32	109.0	183	224
UBD/Beta-Prp	6.90e-68	229.4	13	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD  +k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++gt+ vw+ +t+  +++++ +e +v+  kf  ++ + +tg++D+ ++v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMVVSLYSGTVVVWNHETQMIVKTFELCELPVRVAKFVARKHWVITGADDMQVRVFNYNTLERVHLFEAHSDY 101
           67899************************************************************************************ PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd++ ++  +++++gh++ v+ +v++p + n ++s+slDrt+++W+l ++    tl+g h++ v+
   Q: 102  IRCIAVHPTQPYILTSSDDMLIKLWDWDRKWLCSQVFEGHSHYVMQIVINPRDnNQFASASLDRTIKVWQLGSKAPNFTLEG-HEKGVN 189
           *******************************9999*****************99***************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d+ vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++g++Dg++r+W + +  l +tl++  ++v++++
   Q: 190  CIDYYSGGdkPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVTCVSFHPQLPIILTGAEDGTVRVWHSNTYRLENTLNYGMERVWCIC 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlg 283
           + +++ n ++ g
   Q: 279  G-QPSSNSVAIG 289
           *.6665554433 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MPLRLDIKRK LTARSDRVKS VDLHPTEPWM VVSLYSGTVV VWNHETQMIV KTFELCELPV 60
RVAKFVARKH WVITGADDMQ VRVFNYNTLE RVHLFEAHSD YIRCIAVHPT QPYILTSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAATCCA CGTTGGATGA AGCTGTGTAA ATCACACAGC GGCGGCTGAG ATATACAGGC 60
CGGAAATTCT TGTCTTCACA AGAAAAGATT TATGTTGTTG CTGAGCAATA CGAAATGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007914	Ashbya gossypii	45.69	0.00e+00	756.00
IUUC-Gac-041816	Gasterosteus aculeatus	85.65	0.00e+00	1565.00
IUUC-Kpa-049265	Komagataella pastoris	49.19	0.00e+00	865.00
IUUC-Pfo-096737	Poecilia formosa	81.51	0.00e+00	1535.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence