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Tag Content
iUUCD ID IUUC-Psi-092971
Ensembl Protein ID ENSPSIP00000012638.1
UniProt Accession K7FX78; K7FX78_PELSI
Genbank Protein ID ENSPSIP00000012638
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AGCU01130517
Gene Name USP33
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPSIG00000011185.1 ENSPSIT00000012699.1 ENSPSIP00000012638.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.00e-114 381.3 154 684
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tGlkN+gNtCYmN++LQ+Lsn+p+l++++l+     + + +++++k +++ks+ kl++elw ks+ ++v p++l++ +k+++++f+gy+
   Q: 154  TGLKNIGNTCYMNAALQALSNCPPLTQFFLD-----CGALARTDKKPAICKSYLKLMTELWhKSRPGSVVPTNLFQGIKTINPMFRGYS 237
           7******************************.....9999999******************99************************** PP
   S: 89   qqDaqEflaflldqleeelkk.......eknkpkeeeeeedkselsde......................................... 129
           qqDaqEfl++l+d l+eelk+                   ++++ +++                                         
   Q: 238  QQDAQEFLRCLMDLLHEELKEpvmeiedT-----------QSTSIEENveedkslsdvdfqscescgssdkaenetgsrpfsedhaeat 315
           *******************7765555533...........3333333333444455557****************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 316  mliqddenhsltskdwqkektlynklnlassmedlkkdtniasetaeflhnpgtvkvqihsrisdyindvhmtdlsapqsppsnegvna 404
           ***************************************************************************************** PP
   S: 130  ............................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..... 185
                                        ++kk+kk+ks+isd+F+g++ s+++cl+cd+vs++ e+f+dlslp+pgke+ +k+     
   Q: 405  hlsttppksaslwsglatahkkvptvssPKKKKHKKYKSVISDIFDGTIVSSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLhsssh 493
           ***************************98899999********************************************99888***** PP
   S: 186  ............................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevL 230
                                                       +lqdcL++f++++el+g+n+y+cekckk+++ +k +k++k+Pe+L
   Q: 494  qtsliktgscgeayapqgwiaffveyfkrfviscvpswfwgpvvTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQKFPEIL 582
           ***************************************************************************************** PP
   S: 231  ilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev 317
           ++hLkRf  ++e ++++ki ++v+fple Ldl+pf+++++ +q   ++Y+L++v++H+G++ssGHY+ay++n+ ++ W++fdD++Vtev
   Q: 583  CIHLKRF--RHELMFSTKIGTHVSFPLEgLDLQPFVAKDSPAQ--IVTYDLLSVICHHGTASSGHYIAYCRNNLNNlWYEFDDQSVTEV 667
           *******..9999*************************88777..9**************************88889************ PP
   S: 318  keeevleetgstaYvlfYkr 337
           +e++v++   ++aYvlfY++
   Q: 668  PESTVQN---AEAYVLFYRK 684
           *******...********98 PP
   
Organism Pelodiscus sinensis
Protein Sequence
(Fasta)
KMSALSCDCP HLESVGEITK EELIQKSHGT CQDCKVRGPN LWACLENRCS YVGCGESHVD 60
HSTIHSQDTK HCLTVNLTTL RVWCYACSKE VFLDRKLGSH SPLPNARLSH QTQGNSLQDF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Psi-092971|DUB,USP|Pelodiscus sinensis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCGGCGGAT CAGGCAGTAG GAAGCGGAAG GAGCTGCCGC TGCGGGCAGC AGGGACAAGC 60
GAACACCGGC TACCGCCAAG CAGGTGAGGC TGCCGCGCAG CGAGTATGGA GCCCGGGCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Psi-092971|DUB,USP|Pelodiscus sinensis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
SM00290--ZnF_UBP
Gene Ontology

GO:0005776--C:autophagosome
GO:0044297--C:cell body
GO:0005813--C:centrosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0007411--P:axon guidance
GO:0016477--P:cell migration
GO:0009267--P:cellular response to starvation
GO:0051298--P:centrosome duplication
GO:0032091--P:negative regulation of protein binding
GO:0032092--P:positive regulation of protein binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050821--P:protein stabilization
GO:0010506--P:regulation of autophagy
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001742 Ailuropoda melanoleuca 82.92 0.00e+00 1530.00
IUUC-Apl-003987 Anas platyrhynchos 86.42 0.00e+00 1574.00
IUUC-Aca-004713 Anolis carolinensis 80.39 0.00e+00 1459.00
IUUC-Bta-013132 Bos taurus 83.06 0.00e+00 1529.00
IUUC-Cel-018627 Caenorhabditis elegans 34.16 1.00e-37 151.00
IUUC-Cja-018811 Callithrix jacchus 83.17 0.00e+00 1541.00
IUUC-Cfa-021158 Canis familiaris 83.13 0.00e+00 1539.00
IUUC-Cpo-021910 Cavia porcellus 76.61 0.00e+00 1354.00
IUUC-Csa-023130 Chlorocebus sabaeus 83.15 0.00e+00 1536.00
IUUC-Cho-024383 Choloepus hoffmanni 63.81 6.00e-147 514.00
IUUC-Csv-025889 Ciona savignyi 43.71 3.00e-35 140.00
IUUC-Dre-028639 Danio rerio 71.00 0.00e+00 1265.00
IUUC-Dno-029416 Dasypus novemcinctus 82.73 0.00e+00 1507.00
IUUC-Ete-032994 Echinops telfairi 67.72 0.00e+00 708.00
IUUC-Eca-034248 Equus caballus 83.30 0.00e+00 1535.00
IUUC-Eeu-035357 Erinaceus europaeus 66.52 0.00e+00 1123.00
IUUC-Fca-036013 Felis catus 80.81 0.00e+00 1480.00
IUUC-Fal-037509 Ficedula albicollis 85.40 0.00e+00 1571.00
IUUC-Gmo-038944 Gadus morhua 67.18 0.00e+00 1193.00
IUUC-Gga-040647 Gallus gallus 84.54 0.00e+00 1538.00
IUUC-Gac-041752 Gasterosteus aculeatus 69.77 0.00e+00 1263.00
IUUC-Hsa-045694 Homo sapiens 82.51 0.00e+00 1521.00
IUUC-Itr-049041 Ictidomys tridecemlineatus 82.62 0.00e+00 1507.00
IUUC-Kpa-049198 Komagataella pastoris 33.20 5.00e-29 122.00
IUUC-Lch-050400 Latimeria chalumnae 71.58 0.00e+00 1300.00
IUUC-Loc-052616 Lepisosteus oculatus 72.32 0.00e+00 1329.00
IUUC-Laf-053493 Loxodonta africana 83.08 0.00e+00 1531.00
IUUC-Mcc-055542 Macaca mulatta 83.39 0.00e+00 1541.00
IUUC-Meu-056645 Macropus eugenii 69.98 0.00e+00 1204.00
IUUC-Mga-060019 Meleagris gallopavo 84.69 0.00e+00 1301.00
IUUC-Mmr-061241 Microcebus murinus 80.22 0.00e+00 1489.00
IUUC-Mmu-063786 Mus musculus 80.74 0.00e+00 1462.00
IUUC-Mpu-065772 Mustela putorius furo 83.49 0.00e+00 1272.00
IUUC-Mlu-067732 Myotis lucifugus 81.74 0.00e+00 1510.00
IUUC-Nle-069528 Nomascus leucogenys 82.37 0.00e+00 1538.00
IUUC-Opr-070606 Ochotona princeps 79.02 0.00e+00 1359.00
IUUC-Ont-071495 Oreochromis niloticus 71.41 0.00e+00 1270.00
IUUC-Oan-073695 Ornithorhynchus anatinus 83.18 0.00e+00 1030.00
IUUC-Ocu-074457 Oryctolagus cuniculus 81.22 0.00e+00 1495.00
IUUC-Ola-086739 Oryzias latipes 69.34 0.00e+00 1281.00
IUUC-Oga-088720 Otolemur garnettii 83.15 0.00e+00 1543.00
IUUC-Oar-089921 Ovis aries 82.97 0.00e+00 1533.00
IUUC-Ptr-090526 Pan troglodytes 82.62 0.00e+00 1525.00
IUUC-Pan-092396 Papio anubis 83.22 0.00e+00 1533.00
IUUC-Pfo-097415 Poecilia formosa 70.03 0.00e+00 1275.00
IUUC-Pab-098740 Pongo abelii 83.02 0.00e+00 1559.00
IUUC-Pva-102820 Pteropus vampyrus 79.63 0.00e+00 1285.00
IUUC-Rno-104894 Rattus norvegicus 80.44 0.00e+00 1465.00
IUUC-Sha-107244 Sarcophilus harrisii 74.57 0.00e+00 1329.00
IUUC-Sar-113665 Sorex araneus 81.09 0.00e+00 1522.00
IUUC-Ssc-115793 Sus scrofa 80.90 0.00e+00 1467.00
IUUC-Tgu-117487 Taeniopygia guttata 85.96 0.00e+00 1533.00
IUUC-Tru-117694 Takifugu rubripes 68.89 0.00e+00 1275.00
IUUC-Tsy-119598 Tarsius syrichta 73.03 0.00e+00 1253.00
IUUC-Tni-120189 Tetraodon nigroviridis 66.99 0.00e+00 1198.00
IUUC-Tbe-128125 Tupaia belangeri 73.75 1.00e-96 347.00
IUUC-Ttr-128269 Tursiops truncatus 80.66 0.00e+00 1427.00
IUUC-Vpa-130598 Vicugna pacos 81.35 0.00e+00 1489.00
IUUC-Xtr-132044 Xenopus tropicalis 74.62 0.00e+00 1315.00
Created Date 25-Jun-2017

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