iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-019306

Ensembl Protein ID

ENSCJAP00000003055.2

UniProt Accession

F7G7D3; F7G7D3_CALJA

Genbank Protein ID

JAB07252.1; JAB38047.1

Protein Name

Frataxin, mitochondrial isoform 1 preproprotein

Genbank Nucleotide ID

ACFV01071181; GAMQ01003804

Gene Name

FXN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000001695.2	ENSCJAT00000052689.1	ENSCJAP00000049965.1
ENSCJAG00000001695.2	ENSCJAT00000003215.2	ENSCJAP00000003046.2
ENSCJAG00000001695.2	ENSCJAT00000003224.2	ENSCJAP00000003055.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Other/Other	85.92	3.00e-92	335.00	IUUC-Hsa-046921

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MWTLGRRSAA GFLLWPSYTS PAQVQTVTRA PRPGELAQLC DCRALHTGIA KICASRHASL 60
NLRGLNQIQN VKKQSAYLMN LRKTGTLGHP GSLDETTYER LAEETLDSLA EFFEDLADKP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTACACGGC TTACCTCATT TTATCATTAC TACAATCCTA TGAAGTAGGA ACTTTTATAA 60
ACCGCATTTT ATAAACAAGG CACAGAGAGG TTAATTAACT TGCCCACTGT TCACACAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR017789--Frataxin
IPR002908--Frataxin/CyaY
IPR020895--Frataxin_CS

PROSITE

PS01344--FRATAXIN_1
PS50810--FRATAXIN_2

Pfam

PF01491--Frataxin_Cyay

PRINTS

PR00904--FRATAXIN

SMART

SM01219--Frataxin_Cyay

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0051537--F:2 iron, 2 sulfur cluster binding
GO:0008199--F:ferric iron binding
GO:0008198--F:ferrous iron binding
GO:0004322--F:ferroxidase activity
GO:0034986--F:iron chaperone activity
GO:0007628--P:adult walking behavior
GO:0009060--P:aerobic respiration
GO:0006879--P:cellular iron ion homeostasis
GO:0070301--P:cellular response to hydrogen peroxide
GO:0009792--P:embryo development ending in birth or egg hatching
GO:0018283--P:iron incorporation into metallo-sulfur cluster
GO:0007005--P:mitochondrion organization
GO:0040015--P:negative regulation of multicellular organism growth
GO:0046621--P:negative regulation of organ growth
GO:0090201--P:negative regulation of release of cytochrome c from mitochondria
GO:0006119--P:oxidative phosphorylation
GO:1904234--P:positive regulation of aconitate hydratase activity
GO:0030307--P:positive regulation of cell growth
GO:0008284--P:positive regulation of cell proliferation
GO:1904231--P:positive regulation of succinate dehydrogenase activity
GO:0019230--P:proprioception
GO:0016540--P:protein autoprocessing
GO:0010722--P:regulation of ferrochelatase activity
GO:0010039--P:response to iron ion

KEGG

cjc:100390674

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002122	Ailuropoda melanoleuca	73.56	2.00e-79	288.00
IUUC-Apl-003853	Anas platyrhynchos	84.30	2.00e-57	213.00
IUUC-Aca-005026	Anolis carolinensis	72.48	1.00e-59	221.00
IUUC-Aly-006200	Arabidopsis lyrata	44.79	4.00e-19	87.40
IUUC-Ath-007033	Arabidopsis thaliana	44.79	4.00e-19	87.80
IUUC-Ago-007707	Ashbya gossypii	45.45	6.00e-19	85.50
IUUC-Acl-008146	Aspergillus clavatus	32.32	9.00e-19	86.70
IUUC-Afl-008501	Aspergillus flavus	45.78	2.00e-14	72.00
IUUC-Afu-008851	Aspergillus fumigatus	30.48	8.00e-18	83.60
IUUC-Ani-009129	Aspergillus nidulans	40.00	9.00e-12	63.20
IUUC-Ang-009557	Aspergillus niger	37.90	5.00e-17	80.90
IUUC-Ate-010486	Aspergillus terreus	32.37	8.00e-18	83.60
IUUC-Bgr-012108	Blumeria graminis	41.88	1.00e-15	76.30
IUUC-Bta-013437	Bos taurus	75.00	2.00e-78	284.00
IUUC-Bci-013810	Botrytis cinerea	53.25	2.00e-15	75.90
IUUC-Bdi-014226	Brachypodium distachyon	43.90	1.00e-24	105.00
IUUC-Bol-015092	Brassica oleracea	48.86	2.00e-19	89.00
IUUC-Bra-017945	Brassica rapa	48.86	5.00e-19	87.00
IUUC-Cel-018466	Caenorhabditis elegans	51.38	1.00e-25	108.00
IUUC-Cfa-020063	Canis familiaris	72.99	5.00e-80	290.00
IUUC-Cpo-021325	Cavia porcellus	72.99	1.00e-80	291.00
IUUC-Cre-022889	Chlamydomonas reinhardtii	53.19	2.00e-21	95.10
IUUC-Csa-023739	Chlorocebus sabaeus	85.92	3.00e-105	373.00
IUUC-Cho-024324	Choloepus hoffmanni	78.77	2.00e-79	288.00
IUUC-Cgl-026402	Colletotrichum gloeosporioides	44.74	7.00e-19	87.00
IUUC-Cne-027094	Cryptococcus neoformans	39.51	3.00e-13	67.80
IUUC-Cme-027112	Cyanidioschyzon merolae	47.78	2.00e-13	67.80
IUUC-Dre-028813	Danio rerio	66.12	3.00e-45	174.00
IUUC-Dno-029949	Dasypus novemcinctus	88.89	5.00e-57	212.00
IUUC-Dse-031482	Dothistroma septosporum	40.17	2.00e-18	85.90
IUUC-Dme-031608	Drosophila melanogaster	53.28	3.00e-33	134.00
IUUC-Ete-032937	Echinops telfairi	96.88	3.00e-13	67.80
IUUC-Eca-033899	Equus caballus	90.20	2.00e-64	237.00
IUUC-Fca-036579	Felis catus	76.27	2.00e-62	231.00
IUUC-Fox-037940	Fusarium oxysporum	36.81	9.00e-23	99.80
IUUC-Fso-038465	Fusarium solani	50.88	3.00e-23	101.00
IUUC-Ggr-040089	Gaeumannomyces graminis	45.61	8.00e-21	93.20
IUUC-Gga-040910	Gallus gallus	75.68	3.00e-63	234.00
IUUC-Gma-044349	Glycine max	44.63	2.00e-24	105.00
IUUC-Ggo-044854	Gorilla gorilla	86.85	6.00e-92	329.00
IUUC-Hsa-046921	Homo sapiens	85.92	2.00e-90	324.00
IUUC-Hvu-047142	Hordeum vulgare	46.49	4.00e-24	104.00
IUUC-Kpa-049187	Komagataella pastoris	41.23	9.00e-16	76.30
IUUC-Lch-050614	Latimeria chalumnae	57.63	7.00e-55	206.00
IUUC-Lpe-051184	Leersia perrieri	42.98	3.00e-23	101.00
IUUC-Loc-052083	Lepisosteus oculatus	69.42	9.00e-48	181.00
IUUC-Lma-053209	Leptosphaeria maculans	41.96	2.00e-15	75.10
IUUC-Laf-054090	Loxodonta africana	76.30	1.00e-83	302.00
IUUC-Meu-056814	Macropus eugenii	78.91	4.00e-67	246.00
IUUC-Mor-057169	Magnaporthe oryzae	48.72	2.00e-22	99.00
IUUC-Mpo-057483	Magnaporthe poae	47.37	4.00e-22	97.80
IUUC-Mtr-058166	Medicago truncatula	49.52	2.00e-19	88.60
IUUC-Mla-059015	Melampsora laricipopulina	41.46	5.00e-19	86.70
IUUC-Mvi-060356	Microbotryum violaceum	51.06	2.00e-20	91.70
IUUC-Mdo-062658	Monodelphis domestica	70.72	8.00e-69	253.00
IUUC-Mmu-063470	Mus musculus	71.09	2.00e-77	281.00
IUUC-Mac-065327	Musa acuminata	47.11	5.00e-25	107.00
IUUC-Mpu-065761	Mustela putorius furo	83.87	1.00e-67	248.00
IUUC-Mlu-067175	Myotis lucifugus	81.77	5.00e-82	296.00
IUUC-Nfi-068535	Neosartorya fischeri	38.02	8.00e-18	83.60
IUUC-Ncr-068966	Neurospora crassa	44.00	4.00e-22	97.40
IUUC-Opr-070533	Ochotona princeps	52.90	9.00e-31	125.00
IUUC-Oan-073024	Ornithorhynchus anatinus	80.54	2.00e-57	214.00
IUUC-Ocu-074451	Oryctolagus cuniculus	77.05	2.00e-71	262.00
IUUC-Oba-075540	Oryza barthii	44.92	7.00e-24	103.00
IUUC-Obr-076285	Oryza brachyantha	42.15	1.00e-23	103.00
IUUC-Ogl-077827	Oryza glaberrima	44.92	7.00e-24	103.00
IUUC-Ogu-078491	Oryza glumaepatula	44.92	6.00e-24	103.00
IUUC-Oin-080149	Oryza indica	45.61	1.00e-23	102.00
IUUC-Olo-080318	Oryza longistaminata	43.33	1.00e-21	95.50
IUUC-Oni-083037	Oryza nivara	44.92	7.00e-24	103.00
IUUC-Opu-083448	Oryza punctata	43.09	4.00e-24	104.00
IUUC-Oru-084793	Oryza rufipogon	44.92	8.00e-24	103.00
IUUC-Osa-086032	Oryza sativa	44.92	7.00e-24	103.00
IUUC-Ola-086956	Oryzias latipes	64.06	2.00e-43	167.00
IUUC-Olu-087806	Ostreococcus lucimarinus	40.00	1.00e-16	79.00
IUUC-Oga-089029	Otolemur garnettii	81.52	3.00e-87	314.00
IUUC-Oar-089471	Ovis aries	71.70	7.00e-75	273.00
IUUC-Pan-092091	Papio anubis	87.32	6.00e-107	379.00
IUUC-Psi-093193	Pelodiscus sinensis	76.00	9.00e-66	241.00
IUUC-Pma-094540	Petromyzon marinus	62.18	2.00e-41	160.00
IUUC-Pno-094873	Phaeosphaeria nodorum	36.31	1.00e-17	82.80
IUUC-Ppa-095343	Physcomitrella patens	46.59	6.00e-18	84.30
IUUC-Pfo-097093	Poecilia formosa	61.72	7.00e-44	169.00
IUUC-Pab-098781	Pongo abelii	98.78	1.00e-30	124.00
IUUC-Pop-098983	Populus trichocarpa	41.30	6.00e-23	100.00
IUUC-Pca-100872	Procavia capensis	69.67	1.00e-63	235.00
IUUC-Ppe-101711	Prunus persica	51.14	9.00e-20	89.70
IUUC-Pva-102256	Pteropus vampyrus	74.06	4.00e-79	286.00
IUUC-Pgr-103607	Puccinia graminis	43.55	8.00e-21	93.20
IUUC-Pte-104220	Pyrenophora teres	38.14	2.00e-15	74.30
IUUC-Pyt-104562	Pyrenophora triticirepentis	34.19	4.00e-16	77.80
IUUC-Rno-105021	Rattus norvegicus	68.25	1.00e-74	272.00
IUUC-Sce-106182	Saccharomyces cerevisiae	49.30	2.00e-15	75.50
IUUC-Sha-107279	Sarcophilus harrisii	82.88	1.00e-68	252.00
IUUC-Sja-107819	Schizosaccharomyces japonicus	42.02	5.00e-20	90.10
IUUC-Spo-108197	Schizosaccharomyces pombe	38.93	3.00e-21	94.40
IUUC-Smo-108810	Selaginella moellendorffii	54.76	2.00e-21	94.00
IUUC-Sit-110256	Setaria italica	43.86	6.00e-23	100.00
IUUC-Sly-111448	Solanum lycopersicum	45.61	2.00e-22	99.00
IUUC-Stu-112702	Solanum tuberosum	45.61	1.00e-22	99.40
IUUC-Sbi-113956	Sorghum bicolor	40.37	3.00e-25	107.00
IUUC-Sre-115024	Sporisorium reilianum	37.31	2.00e-16	79.00
IUUC-Ssc-116034	Sus scrofa	77.25	1.00e-84	305.00
IUUC-Tgu-117503	Taeniopygia guttata	76.22	1.00e-57	214.00
IUUC-Tsy-119166	Tarsius syrichta	66.67	5.00e-44	169.00
IUUC-Tni-120703	Tetraodon nigroviridis	40.44	5.00e-24	103.00
IUUC-Tca-121473	Theobroma cacao	51.14	2.00e-19	88.60
IUUC-Tre-122241	Trichoderma reesei	45.16	5.00e-20	89.70
IUUC-Tvi-122347	Trichoderma virens	42.74	1.00e-18	85.90
IUUC-Tae-124560	Triticum aestivum	44.95	6.00e-23	100.00
IUUC-Tur-126452	Triticum urartu	46.43	3.00e-24	104.00
IUUC-Tme-127205	Tuber melanosporum	49.48	4.00e-19	85.90
IUUC-Ttr-128186	Tursiops truncatus	77.47	2.00e-75	274.00
IUUC-Uma-129523	Ustilago maydis	34.33	6.00e-15	73.90
IUUC-Vda-129793	Verticillium dahliae	45.61	2.00e-20	91.70
IUUC-Vpa-130040	Vicugna pacos	88.31	8.00e-75	271.00
IUUC-Vvi-131588	Vitis vinifera	50.00	1.00e-19	89.70
IUUC-Yli-134631	Yarrowia lipolytica	49.41	1.00e-17	82.40
IUUC-Zma-135478	Zea mays	46.22	1.00e-25	109.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence