iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115666

Ensembl Protein ID

ENSSSCP00000005510.2

UniProt Accession

F1SP81; F1SP81_PIG

Genbank Protein ID

ENSSSCP00000005510

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU313306

Gene Name

PLAA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000005126.2	ENSSSCT00000005651.2	ENSSSCP00000005510.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-26	90.1	153	183
UBD/Beta-Prp	3.20e-64	217.2	16	308

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v++++  ++ +l+++Gs D+tik+W 
   Q: 153  GHTAAVWAVKIlPEqGLMLTGSADKTIKLWK 183
           8*********99999***************7 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkf.spdksllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgk.....ilvtgseDrtikvwdl 81
           ++l gh+ +v   v++  p +  +++ srd+t+++w  ++++     ++++sgh+++v++v+++p+++     +++tg++D++i++++l
   Q: 16   CSLPGHELDVRGLVCClYPPGA-FVSVSRDRTTRLWVPDSPNRgfteMHCMSGHSNFVSCVCIIPSSDmyphgLIATGGNDHNICIFSL 103
           7788899999999999666666.888889***********99999******************************************** PP
   S: 82   stgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           +++ ++++lkgh+++v+sls+ +   +l+sGs+d t++vw   +++c+  tl+gh+++v+ v++ p++ l+ +Gs+D+t++lW  k g+
   Q: 104  ESPAPLYVLKGHKNTVCSLSSGK-FGTLLSGSWDTTAKVW--LNDKCMM-TLQGHTAAVWAVKILPEQGLMLTGSADKTIKLW--KAGR 186
           **********************9.9***************..9******.*********************************..88** PP
   S: 171  llrtl..tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdll 257
           + rt+   g h+d v+ l++ s+ +e++s+++d +++ w++ tgec++ + ght+ ++s+ ++pn + +v++++D+s+riW  ++g++ 
   Q: 187  CERTFsdIG-HEDCVRGLAILSE-TEFLSCANDASIRKWQI-TGECLEVFYGHTNYIYSISVFPNCKDFVTTGEDRSLRIW--KHGECA 270
           *****8555.*********9996.8****************.***************************************..9***** PP
   S: 258  ktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkkn 297
           +t+ l+++s+++++v  +++  +v g++d++++++  +++
   Q: 271  QTIRLPAQSIWCCCV--LNNGDIVVGASDGIIRVFTESED 308
           ***************..99***************997766 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

PARAMASGAT RYRLSCSLPG HELDVRGLVC CLYPPGAFVS VSRDRTTRLW VPDSPNRGFT 60
EMHCMSGHSN FVSCVCIIPS SDMYPHGLIA TGGNDHNICI FSLESPAPLY VLKGHKNTVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACGCGGGCT CGGAAAAGAC CCGGATTCCG GCAACGGGGC GGGACAGTGG CGTCTTTCTT 60
TGCCCCCAGT CCAGAGCGTG GGAACCAAGC GAGCTTCAAC TCTGTGTCGG CCTCAGCACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0016005--F:phospholipase A2 activator activity
GO:0043130--F:ubiquitin binding
GO:0006954--P:inflammatory response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010992--P:ubiquitin homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	30.86	3.00e-90	325.00
IUUC-Aml-002125	Ailuropoda melanoleuca	95.28	0.00e+00	1598.00
IUUC-Atr-002554	Amborella trichopoda	30.69	1.00e-94	340.00
IUUC-Apl-004094	Anas platyrhynchos	81.14	0.00e+00	1256.00
IUUC-Aca-004726	Anolis carolinensis	80.12	0.00e+00	1313.00
IUUC-Aly-005961	Arabidopsis lyrata	32.63	1.00e-107	384.00
IUUC-Ath-006639	Arabidopsis thaliana	32.14	3.00e-103	369.00
IUUC-Ago-007772	Ashbya gossypii	29.99	9.00e-80	291.00
IUUC-Acl-008316	Aspergillus clavatus	31.98	6.00e-88	318.00
IUUC-Afl-008532	Aspergillus flavus	32.38	1.00e-90	327.00
IUUC-Afu-008950	Aspergillus fumigatus	33.08	2.00e-91	330.00
IUUC-Ani-009186	Aspergillus nidulans	33.42	1.00e-94	340.00
IUUC-Ang-009575	Aspergillus niger	31.09	1.00e-86	314.00
IUUC-Aor-010086	Aspergillus oryzae	32.38	1.00e-90	327.00
IUUC-Ate-010541	Aspergillus terreus	30.33	6.00e-86	311.00
IUUC-Ame-011633	Astyanax mexicanus	66.13	0.00e+00	1107.00
IUUC-Bgr-012292	Blumeria graminis	30.78	1.00e-92	334.00
IUUC-Bta-013218	Bos taurus	95.50	0.00e+00	1595.00
IUUC-Bci-013876	Botrytis cinerea	32.78	1.00e-94	340.00
IUUC-Bdi-014810	Brachypodium distachyon	33.33	4.00e-105	375.00
IUUC-Bol-016006	Brassica oleracea	32.59	3.00e-106	379.00
IUUC-Bra-017593	Brassica rapa	32.86	8.00e-107	381.00
IUUC-Cel-018703	Caenorhabditis elegans	27.43	1.00e-70	261.00
IUUC-Cja-019270	Callithrix jacchus	93.00	0.00e+00	1554.00
IUUC-Cfa-021262	Canis familiaris	95.26	0.00e+00	1587.00
IUUC-Cpo-021449	Cavia porcellus	87.27	0.00e+00	1441.00
IUUC-Csa-024140	Chlorocebus sabaeus	93.50	0.00e+00	1562.00
IUUC-Cho-024923	Choloepus hoffmanni	92.50	0.00e+00	753.00
IUUC-Cin-025373	Ciona intestinalis	39.68	6.00e-172	597.00
IUUC-Csv-026324	Ciona savignyi	41.25	0.00e+00	635.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	31.95	2.00e-88	320.00
IUUC-Cne-026998	Cryptococcus neoformans	30.58	3.00e-86	313.00
IUUC-Cme-027154	Cyanidioschyzon merolae	29.70	5.00e-53	202.00
IUUC-Dre-028674	Danio rerio	64.68	0.00e+00	1087.00
IUUC-Dno-028966	Dasypus novemcinctus	92.77	0.00e+00	1559.00
IUUC-Dor-030343	Dipodomys ordii	85.83	0.00e+00	887.00
IUUC-Dse-031385	Dothistroma septosporum	30.35	4.00e-81	295.00
IUUC-Dme-032044	Drosophila melanogaster	36.23	2.00e-125	442.00
IUUC-Ete-032506	Echinops telfairi	82.68	0.00e+00	824.00
IUUC-Eca-033547	Equus caballus	95.12	0.00e+00	1587.00
IUUC-Eeu-034462	Erinaceus europaeus	79.42	0.00e+00	681.00
IUUC-Fca-035893	Felis catus	94.88	0.00e+00	1581.00
IUUC-Fal-037235	Ficedula albicollis	81.59	0.00e+00	1369.00
IUUC-Fox-037836	Fusarium oxysporum	31.58	8.00e-97	347.00
IUUC-Fso-038251	Fusarium solani	31.02	1.00e-95	343.00
IUUC-Gmo-038648	Gadus morhua	65.74	0.00e+00	959.00
IUUC-Ggr-039867	Gaeumannomyces graminis	30.72	1.00e-85	310.00
IUUC-Gga-040989	Gallus gallus	79.53	0.00e+00	1315.00
IUUC-Gac-041344	Gasterosteus aculeatus	65.97	0.00e+00	1063.00
IUUC-Gma-043067	Glycine max	31.60	7.00e-104	371.00
IUUC-Ggo-045009	Gorilla gorilla	92.99	0.00e+00	1200.00
IUUC-Hsa-046807	Homo sapiens	93.50	0.00e+00	1558.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	94.01	0.00e+00	1565.00
IUUC-Kpa-049134	Komagataella pastoris	42.80	1.00e-86	313.00
IUUC-Lch-049597	Latimeria chalumnae	73.11	0.00e+00	733.00
IUUC-Lpe-050821	Leersia perrieri	31.45	6.00e-97	348.00
IUUC-Loc-051849	Lepisosteus oculatus	72.24	0.00e+00	1201.00
IUUC-Lma-053297	Leptosphaeria maculans	33.59	6.00e-105	374.00
IUUC-Laf-053495	Loxodonta africana	93.26	0.00e+00	1562.00
IUUC-Meu-055983	Macropus eugenii	80.45	0.00e+00	644.00
IUUC-Mor-057006	Magnaporthe oryzae	35.76	8.00e-73	268.00
IUUC-Mpo-057465	Magnaporthe poae	35.85	3.00e-75	276.00
IUUC-Mtr-058374	Medicago truncatula	32.63	9.00e-114	404.00
IUUC-Mla-058895	Melampsora laricipopulina	36.17	1.00e-76	279.00
IUUC-Mvi-060297	Microbotryum violaceum	35.42	2.00e-108	386.00
IUUC-Mmr-060810	Microcebus murinus	88.81	0.00e+00	1456.00
IUUC-Mdo-062671	Monodelphis domestica	86.89	0.00e+00	1427.00
IUUC-Mmu-063536	Mus musculus	92.50	0.00e+00	1517.00
IUUC-Mac-064902	Musa acuminata	32.21	6.00e-100	358.00
IUUC-Mpu-066085	Mustela putorius furo	95.50	0.00e+00	1593.00
IUUC-Mlu-067907	Myotis lucifugus	92.37	0.00e+00	993.00
IUUC-Nfi-068457	Neosartorya fischeri	31.96	2.00e-73	270.00
IUUC-Ncr-068622	Neurospora crassa	30.51	3.00e-95	342.00
IUUC-Nle-069049	Nomascus leucogenys	92.62	0.00e+00	1530.00
IUUC-Opr-071013	Ochotona princeps	73.84	0.00e+00	647.00
IUUC-Ont-071339	Oreochromis niloticus	69.07	0.00e+00	1146.00
IUUC-Oan-073353	Ornithorhynchus anatinus	81.70	2.00e-110	391.00
IUUC-Ocu-074625	Oryctolagus cuniculus	93.75	0.00e+00	1567.00
IUUC-Oba-075226	Oryza barthii	28.93	3.00e-84	305.00
IUUC-Obr-076875	Oryza brachyantha	32.54	5.00e-108	385.00
IUUC-Ogl-077057	Oryza glaberrima	32.17	1.00e-107	383.00
IUUC-Ogu-078156	Oryza glumaepatula	31.90	6.00e-108	385.00
IUUC-Oin-079373	Oryza indica	31.80	3.00e-106	379.00
IUUC-Olo-080849	Oryza longistaminata	29.23	4.00e-73	268.00
IUUC-Ome-081654	Oryza meridionalis	28.69	5.00e-85	308.00
IUUC-Oni-082221	Oryza nivara	29.06	2.00e-87	316.00
IUUC-Opu-084103	Oryza punctata	29.07	6.00e-86	311.00
IUUC-Oru-084751	Oryza rufipogon	28.47	6.00e-84	305.00
IUUC-Osa-085584	Oryza sativa	31.78	7.00e-107	381.00
IUUC-Ola-086974	Oryzias latipes	68.17	0.00e+00	1149.00
IUUC-Oga-088052	Otolemur garnettii	88.64	0.00e+00	1465.00
IUUC-Oar-089509	Ovis aries	95.54	0.00e+00	1605.00
IUUC-Ptr-090911	Pan troglodytes	93.62	0.00e+00	1560.00
IUUC-Pan-092141	Papio anubis	93.51	0.00e+00	1565.00
IUUC-Psi-093543	Pelodiscus sinensis	82.12	0.00e+00	1277.00
IUUC-Pno-094952	Phaeosphaeria nodorum	32.51	2.00e-96	347.00
IUUC-Ppa-095881	Physcomitrella patens	32.76	2.00e-108	386.00
IUUC-Pfo-096739	Poecilia formosa	66.58	0.00e+00	1121.00
IUUC-Pab-098641	Pongo abelii	93.51	0.00e+00	1559.00
IUUC-Pop-099621	Populus trichocarpa	31.40	4.00e-103	369.00
IUUC-Pca-100599	Procavia capensis	84.00	0.00e+00	1295.00
IUUC-Ppe-101874	Prunus persica	31.68	3.00e-108	385.00
IUUC-Pva-103009	Pteropus vampyrus	90.22	0.00e+00	1266.00
IUUC-Pgr-103260	Puccinia graminis	32.82	2.00e-93	336.00
IUUC-Ptt-103711	Puccinia triticina	31.57	1.00e-88	320.00
IUUC-Pte-104337	Pyrenophora teres	32.69	2.00e-96	346.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	33.07	4.00e-98	352.00
IUUC-Rno-105273	Rattus norvegicus	92.88	0.00e+00	1554.00
IUUC-Sce-106351	Saccharomyces cerevisiae	32.06	9.00e-86	311.00
IUUC-Sha-106758	Sarcophilus harrisii	87.17	0.00e+00	1439.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	39.14	7.00e-95	341.00
IUUC-Spo-108093	Schizosaccharomyces pombe	34.52	8.00e-103	367.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	39.80	3.00e-90	326.00
IUUC-Smo-109368	Selaginella moellendorffii	31.00	2.00e-96	346.00
IUUC-Sit-109699	Setaria italica	33.38	3.00e-109	389.00
IUUC-Sly-111063	Solanum lycopersicum	32.12	2.00e-101	362.00
IUUC-Sar-113199	Sorex araneus	94.76	0.00e+00	812.00
IUUC-Sbi-114745	Sorghum bicolor	32.50	3.00e-100	358.00
IUUC-Sre-115080	Sporisorium reilianum	33.17	5.00e-107	381.00
IUUC-Tgu-116877	Taeniopygia guttata	80.80	0.00e+00	1356.00
IUUC-Tru-117580	Takifugu rubripes	66.42	0.00e+00	1123.00
IUUC-Tsy-118946	Tarsius syrichta	93.47	0.00e+00	1435.00
IUUC-Tni-119755	Tetraodon nigroviridis	63.92	0.00e+00	1050.00
IUUC-Tca-120977	Theobroma cacao	30.11	1.00e-100	360.00
IUUC-Tre-122217	Trichoderma reesei	32.42	1.00e-97	350.00
IUUC-Tvi-122671	Trichoderma virens	31.38	3.00e-95	342.00
IUUC-Tae-125581	Triticum aestivum	32.57	2.00e-104	373.00
IUUC-Tur-126404	Triticum urartu	24.10	1.00e-22	101.00
IUUC-Tme-126971	Tuber melanosporum	34.65	6.00e-113	401.00
IUUC-Tbe-127858	Tupaia belangeri	75.00	0.00e+00	637.00
IUUC-Ttr-128173	Tursiops truncatus	93.50	0.00e+00	1532.00
IUUC-Uma-129322	Ustilago maydis	33.33	1.00e-107	383.00
IUUC-Vda-129682	Verticillium dahliae	32.83	5.00e-93	335.00
IUUC-Vpa-130607	Vicugna pacos	92.93	0.00e+00	1416.00
IUUC-Vvi-131153	Vitis vinifera	33.38	4.00e-111	395.00
IUUC-Xtr-132208	Xenopus tropicalis	74.34	0.00e+00	1232.00
IUUC-Xma-133098	Xiphophorus maculatus	67.39	0.00e+00	1115.00
IUUC-Yli-134646	Yarrowia lipolytica	39.06	2.00e-94	339.00
IUUC-Zma-135920	Zea mays	30.56	1.00e-91	330.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence