iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007097

UUCD1 version

UUC-ArT-00272

Ensembl Protein ID

AT4G35050.1

UniProt Accession

O22469; O49612; MSI3_ARATH

Genbank Protein ID

AAB70244.1; CAA17770.1; CAB80222.1; AEE86455.1

Protein Name

WD-40 repeat-containing protein MSI3

Genbank Nucleotide ID

AF016848; AL022023; AL161586; CP002687

Gene Name

MSI3; At4g35050; M4E13.110

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G35050	AT4G35050.1	AT4G35050.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.90e-33	112.0	216	251

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtg 33
           gH++ + ++a+   +++++ s++dD+++ +WDlrt+
   Q: 216  GHQSIIEDVAWhmkNENIFGSAGDDCQLVIWDLRTN 251
           8************766*****************996 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.

Protein Sequence
(Fasta)

MAAEEGKDEA GLDQVEEEFS IWKRNTPFLY DLMISHPLEW PSLTLHWVPS TPIPYSKDPY 60
FAVHKLILGT HTSGGAQDFL MVADVVIPTP DAEPGLGGRD QEPIVPKVEI KQKIRVDGEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAATGTATGC GGTTTTTCAT ATAAATAAAC GTCATGGCGT TTTCGTATAG AACATCGAAA 60
ACAGCATTGT TACCCGCTTC ATTCCTCCTC TCTCTTTTTG GGCGGGAAAC TGTACCAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR022052--Histone-bd_RBBP4_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12265--CAF1C_H4-bd
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

ath:AT4G35050

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005978	Arabidopsis lyrata	98.27	0.00e+00	830.00
IUUC-Kpa-049258	Komagataella pastoris	34.34	2.00e-69	255.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence