iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115720

Ensembl Protein ID

ENSSSCP00000029411.1

UniProt Accession

I3L7X1; I3L7X1_PIG

Genbank Protein ID

ENSSSCP00000020129

Protein Name

V(D)J recombination-activating protein 1

Genbank Nucleotide ID

FP102503

Gene Name

RAG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000026145.2	ENSSSCT00000035942.1	ENSSSCP00000029411.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.66	0.00e+00	1928.00	IUUC-Hsa-045964
E3 activity/RING/RING	87.54	0.00e+00	1865.00	IUUC-Mmu-064297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sus scrofa

Protein Sequence
(Fasta)

MAVSLPPTLG LSSAPDEIQH PHIKFSEWKF KLFRVRSFEK APEKAQTEKQ DSSEGKPSLE 60
QSPAVLDKPG GQKSALPQPA FKPHPKFLKE SHEDGKARDK AIHQANLRRL CRICGNSFNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCTGAGGG ATGGGAGAGC ACATTTTGCC TTCTCTTTGG TAGCGAGTAA TATCAACCGA 60
AGTGCAGACA TCCTAACACT TTGCCCAGGC AGCCTGCTGA GCAAGGTAAC ACTCATCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001206	Ailuropoda melanoleuca	92.23	0.00e+00	1952.00
IUUC-Apl-003271	Anas platyrhynchos	77.40	0.00e+00	1659.00
IUUC-Aca-004400	Anolis carolinensis	73.83	0.00e+00	1606.00
IUUC-Ame-011295	Astyanax mexicanus	58.75	0.00e+00	1211.00
IUUC-Bta-012421	Bos taurus	92.94	0.00e+00	1962.00
IUUC-Cja-019891	Callithrix jacchus	90.89	0.00e+00	1880.00
IUUC-Cfa-020740	Canis familiaris	83.51	0.00e+00	1808.00
IUUC-Cpo-021800	Cavia porcellus	89.12	0.00e+00	1816.00
IUUC-Csa-024203	Chlorocebus sabaeus	91.14	0.00e+00	1710.00
IUUC-Dre-028416	Danio rerio	58.04	0.00e+00	1198.00
IUUC-Dno-029101	Dasypus novemcinctus	90.32	0.00e+00	1877.00
IUUC-Eca-033385	Equus caballus	92.33	0.00e+00	1938.00
IUUC-Fca-036545	Felis catus	91.08	0.00e+00	1929.00
IUUC-Fal-037208	Ficedula albicollis	75.98	0.00e+00	1647.00
IUUC-Gmo-039622	Gadus morhua	54.38	0.00e+00	1152.00
IUUC-Gga-041182	Gallus gallus	76.23	0.00e+00	1616.00
IUUC-Gac-041682	Gasterosteus aculeatus	56.78	0.00e+00	1182.00
IUUC-Ggo-044510	Gorilla gorilla	91.75	0.00e+00	1924.00
IUUC-Hsa-045964	Homo sapiens	91.66	0.00e+00	1924.00
IUUC-Itr-048862	Ictidomys tridecemlineatus	90.60	0.00e+00	1897.00
IUUC-Kpa-049300	Komagataella pastoris	34.29	7.00e-09	54.30
IUUC-Lch-050041	Latimeria chalumnae	69.30	0.00e+00	1467.00
IUUC-Loc-052464	Lepisosteus oculatus	63.26	0.00e+00	1346.00
IUUC-Laf-053544	Loxodonta africana	90.99	0.00e+00	1919.00
IUUC-Mcc-054867	Macaca mulatta	91.28	0.00e+00	1915.00
IUUC-Meu-055986	Macropus eugenii	81.09	0.00e+00	1572.00
IUUC-Mga-059262	Meleagris gallopavo	76.71	0.00e+00	1636.00
IUUC-Mdo-062686	Monodelphis domestica	80.61	0.00e+00	1755.00
IUUC-Mmu-064297	Mus musculus	87.54	0.00e+00	1899.00
IUUC-Mpu-066027	Mustela putorius furo	91.66	0.00e+00	1910.00
IUUC-Mlu-067885	Myotis lucifugus	92.14	0.00e+00	1941.00
IUUC-Nle-070073	Nomascus leucogenys	91.28	0.00e+00	1919.00
IUUC-Ont-071400	Oreochromis niloticus	61.22	0.00e+00	1263.00
IUUC-Oan-072920	Ornithorhynchus anatinus	94.16	0.00e+00	778.00
IUUC-Ocu-074616	Oryctolagus cuniculus	90.89	0.00e+00	1897.00
IUUC-Ola-086828	Oryzias latipes	59.71	0.00e+00	1228.00
IUUC-Oga-088675	Otolemur garnettii	94.46	2.00e-155	540.00
IUUC-Oar-090380	Ovis aries	92.33	0.00e+00	1970.00
IUUC-Ptr-090648	Pan troglodytes	91.85	0.00e+00	1927.00
IUUC-Pan-092036	Papio anubis	91.08	0.00e+00	1910.00
IUUC-Psi-093130	Pelodiscus sinensis	79.44	0.00e+00	1722.00
IUUC-Pfo-097273	Poecilia formosa	59.48	0.00e+00	1210.00
IUUC-Pca-100134	Procavia capensis	84.48	0.00e+00	1772.00
IUUC-Rno-105632	Rattus norvegicus	88.11	0.00e+00	1918.00
IUUC-Sha-107238	Sarcophilus harrisii	80.04	0.00e+00	1754.00
IUUC-Sar-113591	Sorex araneus	79.02	0.00e+00	1623.00
IUUC-Tgu-117030	Taeniopygia guttata	76.97	0.00e+00	1642.00
IUUC-Tru-117669	Takifugu rubripes	57.31	0.00e+00	1134.00
IUUC-Tsy-119578	Tarsius syrichta	86.58	0.00e+00	1825.00
IUUC-Tni-120073	Tetraodon nigroviridis	58.12	0.00e+00	1178.00
IUUC-Tbe-128029	Tupaia belangeri	84.89	0.00e+00	941.00
IUUC-Ttr-128677	Tursiops truncatus	88.08	0.00e+00	818.00
IUUC-Vpa-130346	Vicugna pacos	95.03	0.00e+00	886.00
IUUC-Xtr-132442	Xenopus tropicalis	85.57	4.00e-100	356.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence