iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106661

Ensembl Protein ID

ENSSHAP00000001165.1

UniProt Accession

G3VDB1; G3VDB1_SARHA

Genbank Protein ID

ENSSHAP00000001165

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01234136

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000001040.1	ENSSHAT00000001180.1	ENSSHAP00000001165.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	55.65	0.00e+00	797.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

KRGGRKGSPA PRPSPGLAEA RRRGRAKKLS QVSEQELVTN LQDLDLETES EIPSGTGLVL 60
DERMGSFRCP WDDSFPERPE RLQAVQQQLS RDCLLERCIP IEAQPATPQE LQLVHSQEYV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGAGGGGCG GCCGGAAGGG GTCGCCTGCC CCGCGGCCGA GCCCGGGTTT GGCTGAGGCC 60
CGACGCAGAG GGCGAGCAAA GAAATTGAGT CAAGTGTCTG AGCAAGAGCT GGTGACCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	39.88	5.00e-70	258.00
IUUC-Aml-002087	Ailuropoda melanoleuca	55.83	0.00e+00	829.00
IUUC-Atr-002745	Amborella trichopoda	43.06	4.00e-77	282.00
IUUC-Aca-004303	Anolis carolinensis	50.54	0.00e+00	757.00
IUUC-Aly-006432	Arabidopsis lyrata	44.77	6.00e-75	275.00
IUUC-Ath-007355	Arabidopsis thaliana	45.22	5.00e-78	285.00
IUUC-Ago-007972	Ashbya gossypii	41.71	5.00e-76	278.00
IUUC-Acl-008187	Aspergillus clavatus	44.23	1.00e-77	284.00
IUUC-Afl-008399	Aspergillus flavus	49.17	1.00e-47	184.00
IUUC-Afu-008954	Aspergillus fumigatus	40.11	1.00e-65	244.00
IUUC-Ani-009142	Aspergillus nidulans	43.06	2.00e-75	276.00
IUUC-Aor-010069	Aspergillus oryzae	42.57	8.00e-70	258.00
IUUC-Ate-010291	Aspergillus terreus	43.91	4.00e-79	289.00
IUUC-Ame-010780	Astyanax mexicanus	41.74	0.00e+00	754.00
IUUC-Bta-013052	Bos taurus	55.43	0.00e+00	791.00
IUUC-Bci-013789	Botrytis cinerea	41.76	6.00e-73	268.00
IUUC-Bdi-014007	Brachypodium distachyon	43.10	3.00e-80	293.00
IUUC-Bol-015468	Brassica oleracea	45.77	5.00e-77	281.00
IUUC-Bra-016680	Brassica rapa	45.93	2.00e-77	283.00
IUUC-Cel-018220	Caenorhabditis elegans	33.12	3.00e-98	352.00
IUUC-Cja-019473	Callithrix jacchus	53.59	0.00e+00	744.00
IUUC-Cfa-020263	Canis familiaris	53.38	0.00e+00	803.00
IUUC-Cpo-021691	Cavia porcellus	55.31	0.00e+00	819.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	55.92	3.00e-55	207.00
IUUC-Csa-024223	Chlorocebus sabaeus	53.30	0.00e+00	797.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	41.96	8.00e-76	278.00
IUUC-Cne-026978	Cryptococcus neoformans	47.20	3.00e-82	299.00
IUUC-Dre-028820	Danio rerio	45.04	0.00e+00	649.00
IUUC-Dno-029160	Dasypus novemcinctus	55.30	0.00e+00	800.00
IUUC-Dor-030859	Dipodomys ordii	54.32	0.00e+00	822.00
IUUC-Dse-031186	Dothistroma septosporum	40.78	2.00e-71	264.00
IUUC-Dme-031963	Drosophila melanogaster	36.50	9.00e-139	487.00
IUUC-Ete-032279	Echinops telfairi	49.40	1.00e-104	374.00
IUUC-Eca-033842	Equus caballus	55.64	0.00e+00	825.00
IUUC-Eeu-034487	Erinaceus europaeus	59.87	3.00e-96	346.00
IUUC-Fca-036430	Felis catus	56.00	0.00e+00	805.00
IUUC-Fox-038067	Fusarium oxysporum	42.23	1.00e-77	284.00
IUUC-Fso-038263	Fusarium solani	43.05	6.00e-79	288.00
IUUC-Ggr-040062	Gaeumannomyces graminis	43.05	3.00e-69	256.00
IUUC-Gma-043738	Glycine max	44.02	6.00e-75	275.00
IUUC-Ggo-045022	Gorilla gorilla	53.08	0.00e+00	798.00
IUUC-Hsa-046904	Homo sapiens	55.65	0.00e+00	797.00
IUUC-Hvu-047285	Hordeum vulgare	45.86	5.00e-77	280.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	54.82	0.00e+00	857.00
IUUC-Kpa-049281	Komagataella pastoris	41.55	1.00e-75	277.00
IUUC-Lch-050330	Latimeria chalumnae	44.92	7.00e-161	561.00
IUUC-Lpe-051214	Leersia perrieri	42.49	5.00e-79	288.00
IUUC-Lma-053263	Leptosphaeria maculans	44.57	6.00e-78	285.00
IUUC-Laf-053386	Loxodonta africana	50.23	0.00e+00	927.00
IUUC-Mcc-055530	Macaca mulatta	53.19	0.00e+00	796.00
IUUC-Meu-056442	Macropus eugenii	65.29	0.00e+00	804.00
IUUC-Mor-057095	Magnaporthe oryzae	43.05	5.00e-80	292.00
IUUC-Mpo-057389	Magnaporthe poae	43.60	3.00e-68	253.00
IUUC-Mtr-058463	Medicago truncatula	42.57	2.00e-76	280.00
IUUC-Mla-059143	Melampsora laricipopulina	41.86	2.00e-74	273.00
IUUC-Mmr-060637	Microcebus murinus	56.07	0.00e+00	793.00
IUUC-Mdo-062198	Monodelphis domestica	64.71	0.00e+00	1192.00
IUUC-Mmu-063346	Mus musculus	49.35	0.00e+00	830.00
IUUC-Mac-064630	Musa acuminata	45.02	6.00e-73	268.00
IUUC-Mpu-065884	Mustela putorius furo	55.34	0.00e+00	820.00
IUUC-Mlu-068117	Myotis lucifugus	54.42	0.00e+00	783.00
IUUC-Nfi-068404	Neosartorya fischeri	44.23	5.00e-78	285.00
IUUC-Ncr-068672	Neurospora crassa	43.56	4.00e-78	285.00
IUUC-Nle-069868	Nomascus leucogenys	48.48	3.00e-93	336.00
IUUC-Opr-071074	Ochotona princeps	61.45	1.00e-155	543.00
IUUC-Ont-072246	Oreochromis niloticus	45.48	2.00e-163	570.00
IUUC-Oan-072911	Ornithorhynchus anatinus	73.50	4.00e-99	356.00
IUUC-Ocu-074627	Oryctolagus cuniculus	51.33	0.00e+00	832.00
IUUC-Oba-075489	Oryza barthii	45.05	5.00e-77	281.00
IUUC-Obr-076150	Oryza brachyantha	40.74	6.00e-79	288.00
IUUC-Ogl-077437	Oryza glaberrima	41.91	1.00e-77	283.00
IUUC-Ogu-078370	Oryza glumaepatula	41.91	4.00e-78	285.00
IUUC-Oin-079210	Oryza indica	41.91	5.00e-78	285.00
IUUC-Olo-080971	Oryza longistaminata	46.45	1.00e-71	264.00
IUUC-Oni-082031	Oryza nivara	41.91	6.00e-78	285.00
IUUC-Opu-083471	Oryza punctata	44.41	1.00e-76	280.00
IUUC-Oru-084755	Oryza rufipogon	41.91	4.00e-78	285.00
IUUC-Osa-085447	Oryza sativa	41.91	4.00e-78	285.00
IUUC-Oga-089155	Otolemur garnettii	53.92	0.00e+00	798.00
IUUC-Oar-089620	Ovis aries	55.31	0.00e+00	794.00
IUUC-Ptr-090812	Pan troglodytes	52.90	0.00e+00	654.00
IUUC-Pan-092340	Papio anubis	55.65	0.00e+00	796.00
IUUC-Pma-094386	Petromyzon marinus	44.97	1.00e-164	573.00
IUUC-Pno-095131	Phaeosphaeria nodorum	48.06	2.00e-72	266.00
IUUC-Ppa-095550	Physcomitrella patens	46.18	8.00e-80	291.00
IUUC-Pfo-096110	Poecilia formosa	42.06	0.00e+00	647.00
IUUC-Pab-098422	Pongo abelii	55.10	0.00e+00	764.00
IUUC-Pop-099174	Populus trichocarpa	44.38	5.00e-77	282.00
IUUC-Pca-100833	Procavia capensis	54.39	0.00e+00	796.00
IUUC-Ppe-101644	Prunus persica	43.77	1.00e-79	290.00
IUUC-Pva-102410	Pteropus vampyrus	62.86	7.00e-170	591.00
IUUC-Ptt-103841	Puccinia triticina	38.48	4.00e-70	259.00
IUUC-Pte-104383	Pyrenophora teres	43.80	5.00e-75	275.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	44.38	3.00e-75	276.00
IUUC-Rno-105131	Rattus norvegicus	53.86	0.00e+00	848.00
IUUC-Sce-106274	Saccharomyces cerevisiae	41.43	2.00e-73	270.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	43.52	1.00e-81	297.00
IUUC-Spo-108300	Schizosaccharomyces pombe	46.22	5.00e-81	295.00
IUUC-Smo-109615	Selaginella moellendorffii	45.48	1.00e-82	300.00
IUUC-Sit-110160	Setaria italica	41.91	1.00e-73	270.00
IUUC-Sly-111164	Solanum lycopersicum	40.36	2.00e-75	276.00
IUUC-Stu-112685	Solanum tuberosum	42.74	2.00e-70	260.00
IUUC-Sar-113692	Sorex araneus	39.37	4.00e-91	329.00
IUUC-Sbi-114301	Sorghum bicolor	42.36	1.00e-73	271.00
IUUC-Sre-115013	Sporisorium reilianum	45.85	3.00e-77	283.00
IUUC-Ssc-115724	Sus scrofa	56.00	0.00e+00	795.00
IUUC-Tgu-116605	Taeniopygia guttata	38.63	1.00e-129	456.00
IUUC-Tru-117614	Takifugu rubripes	48.06	1.00e-175	610.00
IUUC-Tsy-118807	Tarsius syrichta	55.84	1.00e-151	530.00
IUUC-Tni-119809	Tetraodon nigroviridis	46.70	6.00e-161	561.00
IUUC-Tca-121312	Theobroma cacao	43.60	3.00e-75	276.00
IUUC-Tre-121930	Trichoderma reesei	43.51	5.00e-82	298.00
IUUC-Tvi-122373	Trichoderma virens	44.81	4.00e-80	292.00
IUUC-Tae-123064	Triticum aestivum	40.82	3.00e-73	268.00
IUUC-Tme-127027	Tuber melanosporum	42.24	2.00e-62	233.00
IUUC-Tbe-127675	Tupaia belangeri	65.79	2.00e-45	177.00
IUUC-Ttr-128411	Tursiops truncatus	53.68	0.00e+00	789.00
IUUC-Uma-129408	Ustilago maydis	46.94	4.00e-69	256.00
IUUC-Vda-129994	Verticillium dahliae	41.64	2.00e-70	260.00
IUUC-Vpa-130525	Vicugna pacos	71.26	1.00e-29	125.00
IUUC-Vvi-131038	Vitis vinifera	41.04	2.00e-75	276.00
IUUC-Xtr-132618	Xenopus tropicalis	49.10	0.00e+00	723.00
IUUC-Xma-133730	Xiphophorus maculatus	55.46	4.00e-141	496.00
IUUC-Yli-134680	Yarrowia lipolytica	42.70	6.00e-80	291.00
IUUC-Zma-135110	Zea mays	41.62	1.00e-73	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence