iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091595

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Genbank Nucleotide ID

AACZ03093813

Gene Name

DCUN1D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000006059.5	ENSPTRT00000011133.4	ENSPTRP00000010301.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	5.80e-91	303.7	59	246

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 1    vskkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktlesel 88
           v+kkkle+l+ rYkdpq++ +igi+g+++fc+dl++dp++i+vLv+awk++aat+cefsr+efldg+t+lgcds+ekl++ l++le+el
   Q: 59   VDKKKLERLYGRYKDPQDEnKIGIDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSRKEFLDGMTELGCDSMEKLKALLPRLEQEL 147
           589**************999********************************************************************* PP
   S: 89   kdeqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaW 177
           kd++kfkd+Y+f+f+fak++gqk+ldl++a+a+wkL+l++r fk+ld+w++fL e++k+si++DtWnllL+f  +ia+d+snYdeegaW
   Q: 148  KDTAKFKDFYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGR-FKFLDLWNTFLLEHHKRSIPRDTWNLLLDFGDMIADDMSNYDEEGAW 235
           ****************************************9.*********************************************** PP
   S: 178  PvliDefveyl 188
           PvliD+fvey+
   Q: 236  PVLIDDFVEYA 246
           *********97 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

HKLKSSQKDK VRQFMACTQA GERTAIYCLT QNEWRLDEAT DSFFQNPDSL HRESMRNAVD 60
KKKLERLYGR YKDPQDENKI GIDGIQQFCD DLSLDPASIS VLVIAWKFRA ATQCEFSRKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGCATAAGC TTAAATCGTC TCAGAAGGAC AAGGTCCGCC AGTTTATGGC GTGCACTCAG 60
GCTGGCGAGA GAACTGCTAT CTACTGCTTA ACGCAGAATG AGTGGAGACT AGACGAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	44.72	7.00e-61	226.00
IUUC-Aml-001808	Ailuropoda melanoleuca	84.55	4.00e-125	440.00
IUUC-Atr-002662	Amborella trichopoda	41.94	1.00e-25	109.00
IUUC-Apl-003933	Anas platyrhynchos	88.63	5.00e-138	483.00
IUUC-Aca-005059	Anolis carolinensis	86.86	6.00e-125	439.00
IUUC-Aly-006285	Arabidopsis lyrata	38.62	2.00e-45	175.00
IUUC-Ath-007531	Arabidopsis thaliana	44.31	2.00e-58	218.00
IUUC-Ame-011739	Astyanax mexicanus	85.06	2.00e-126	444.00
IUUC-Bta-012373	Bos taurus	80.71	2.00e-122	431.00
IUUC-Bol-016110	Brassica oleracea	44.31	1.00e-57	215.00
IUUC-Bra-017111	Brassica rapa	44.31	3.00e-57	214.00
IUUC-Cja-018854	Callithrix jacchus	97.29	8.00e-151	525.00
IUUC-Cpo-021832	Cavia porcellus	92.31	1.00e-142	498.00
IUUC-Csa-023108	Chlorocebus sabaeus	98.45	4.00e-152	530.00
IUUC-Csv-026372	Ciona savignyi	43.82	2.00e-51	195.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	31.28	4.00e-23	100.00
IUUC-Dno-029524	Dasypus novemcinctus	91.80	4.00e-135	473.00
IUUC-Dor-030143	Dipodomys ordii	93.41	3.00e-145	507.00
IUUC-Eca-033375	Equus caballus	89.27	1.00e-125	441.00
IUUC-Fal-036715	Ficedula albicollis	89.41	8.00e-139	485.00
IUUC-Fso-038150	Fusarium solani	25.50	2.00e-20	92.80
IUUC-Gga-040224	Gallus gallus	88.93	8.00e-137	479.00
IUUC-Gac-041478	Gasterosteus aculeatus	85.88	7.00e-134	469.00
IUUC-Ggo-044972	Gorilla gorilla	99.61	1.00e-153	535.00
IUUC-Hsa-046994	Homo sapiens	98.84	2.00e-153	534.00
IUUC-Hvu-047636	Hordeum vulgare	37.21	2.00e-23	102.00
IUUC-Itr-047902	Ictidomys tridecemlineatus	89.45	2.00e-139	487.00
IUUC-Kpa-049127	Komagataella pastoris	30.36	2.00e-23	102.00
IUUC-Lch-049751	Latimeria chalumnae	85.49	1.00e-134	471.00
IUUC-Loc-051976	Lepisosteus oculatus	85.10	3.00e-134	470.00
IUUC-Laf-053972	Loxodonta africana	91.86	1.00e-142	498.00
IUUC-Mcc-054700	Macaca mulatta	98.45	3.00e-152	530.00
IUUC-Meu-056791	Macropus eugenii	74.42	2.00e-109	387.00
IUUC-Mpo-057299	Magnaporthe poae	24.46	1.00e-17	83.20
IUUC-Mga-060072	Meleagris gallopavo	88.63	1.00e-137	481.00
IUUC-Mdo-062241	Monodelphis domestica	86.48	2.00e-128	451.00
IUUC-Mmu-063816	Mus musculus	91.47	1.00e-143	501.00
IUUC-Mac-065016	Musa acuminata	47.90	7.00e-44	169.00
IUUC-Nle-069475	Nomascus leucogenys	98.84	2.00e-152	531.00
IUUC-Ont-071910	Oreochromis niloticus	84.44	3.00e-134	470.00
IUUC-Ocu-074349	Oryctolagus cuniculus	90.87	4.00e-133	466.00
IUUC-Obr-076341	Oryza brachyantha	45.53	5.00e-62	230.00
IUUC-Oga-088621	Otolemur garnettii	95.35	5.00e-148	516.00
IUUC-Pan-092825	Papio anubis	98.06	9.00e-152	528.00
IUUC-Psi-093029	Pelodiscus sinensis	87.97	2.00e-128	451.00
IUUC-Pno-095145	Phaeosphaeria nodorum	32.86	5.00e-26	111.00
IUUC-Ppa-095321	Physcomitrella patens	43.95	5.00e-58	217.00
IUUC-Pab-098197	Pongo abelii	99.18	9.00e-145	505.00
IUUC-Pop-098821	Populus trichocarpa	45.19	1.00e-23	101.00
IUUC-Pca-100195	Procavia capensis	91.09	4.00e-140	489.00
IUUC-Pva-102691	Pteropus vampyrus	93.80	1.00e-145	508.00
IUUC-Ptt-103979	Puccinia triticina	26.44	9.00e-05	41.20
IUUC-Rno-105016	Rattus norvegicus	90.62	1.00e-142	498.00
IUUC-Sha-106542	Sarcophilus harrisii	86.43	3.00e-136	477.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	31.72	1.00e-23	103.00
IUUC-Sit-110613	Setaria italica	45.12	4.00e-61	227.00
IUUC-Sbi-114113	Sorghum bicolor	44.76	4.00e-62	230.00
IUUC-Tgu-117196	Taeniopygia guttata	89.02	1.00e-138	484.00
IUUC-Tru-118119	Takifugu rubripes	82.10	2.00e-131	461.00
IUUC-Tni-120315	Tetraodon nigroviridis	82.49	5.00e-132	463.00
IUUC-Tre-121986	Trichoderma reesei	25.33	4.00e-22	98.60
IUUC-Tvi-122607	Trichoderma virens	32.68	5.00e-30	124.00
IUUC-Tae-125740	Triticum aestivum	38.33	5.00e-55	207.00
IUUC-Tur-126375	Triticum urartu	35.02	6.00e-51	194.00
IUUC-Vda-129929	Verticillium dahliae	31.34	2.00e-22	99.80
IUUC-Zma-135642	Zea mays	45.53	1.00e-61	229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence