iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071997

Ensembl Protein ID

ENSONIP00000012654.1

UniProt Accession

I3JUV9; I3JUV9_ORENI

Genbank Protein ID

ENSONIP00000012654

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01022638

Gene Name

FBXW7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000010062.1	ENSONIT00000012664.1	ENSONIP00000012654.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.20e-60	196.5	469	502
UBD/Beta-Prp	2.90e-102	342.3	220	502

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H++ vtcl+f+ ++++++sdDgt+k+WDl+tg  
   Q: 469  HQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEF 502
           9*********449******************976 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           k+lkgh+++vitc++f   ++ +++gs+d+t+kvw++ tgk+lr+l gh+++v++ ++ ++  i+++gs+Drt+kvw+ +tg+c+htl 
   Q: 220  KVLKGHDDHVITCLQF--CGNRIVSGSDDNTLKVWSAITGKCLRTLVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGECIHTLY 304
           6799************..*******************************************..************************** PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           gh+++v+++++++  +++vsGs+d t+rvwd+++gqcl+ +l gh ++v+cv++++  + +vsG++D +v++Wd +++++l+tl+g ht
   Q: 305  GHTSTVRCMHLHE--KRVVSGSRDATLRVWDIDSGQCLH-VLMGHVAAVRCVQYDG--RRVVSGAYDFMVKVWDPEMETCLHTLQG-HT 387
           *************..************************.****************..***************************9.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvis 269
           ++vysl+fd    ++vsgsld+++++wd++tg+c++tl+gh++ ++ +++   d++lvsg++D +++iWd+++g++l+tlq+++++ ++
   Q: 388  NRVYSLQFDG--IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSA 472
           *********9..9**************************************..************************************ PP
   S: 270  vavlsfgdnvlvlgsedskvniwklkknep 299
           v++l+f++n +++ s+d++v++w+lk+ e+
   Q: 473  VTCLQFNKNFVITSSDDGTVKLWDLKTGEF 502
           *************************98776 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MGFYGTLKMI FYKMKRKLDH GPEVRSFPSG KKPCKGPEYP SPTGIVPCPA TPTTFGHIRT 60
ANGQGQQRRR ITSIQPPTGL QEWLRTFQSW TGPEKLLALD ELIDSCEPTQ VKHMMQVIEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGTTCT ACGGCACTTT AAAGATGATT TTCTACAAAG TGAGTAGGAT TTATGCTCGT 60
ATTATCCGCC GTGTCACCTC CGGCACATCC TCATCTTCTC TCCGTGTGTT TGGCTCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002406	Ailuropoda melanoleuca	94.09	0.00e+00	1047.00
IUUC-Apl-003489	Anas platyrhynchos	93.10	0.00e+00	1050.00
IUUC-Aca-005318	Anolis carolinensis	94.58	0.00e+00	1073.00
IUUC-Ago-007794	Ashbya gossypii	30.66	4.00e-60	226.00
IUUC-Acl-008123	Aspergillus clavatus	32.40	6.00e-75	275.00
IUUC-Afl-008730	Aspergillus flavus	32.16	1.00e-72	268.00
IUUC-Afu-009014	Aspergillus fumigatus	32.33	3.00e-73	270.00
IUUC-Ani-009332	Aspergillus nidulans	33.20	3.00e-77	283.00
IUUC-Ang-009529	Aspergillus niger	33.40	6.00e-73	269.00
IUUC-Aor-010215	Aspergillus oryzae	30.51	3.00e-73	269.00
IUUC-Ate-010535	Aspergillus terreus	32.48	4.00e-75	276.00
IUUC-Ame-010898	Astyanax mexicanus	95.01	0.00e+00	1046.00
IUUC-Bgr-012075	Blumeria graminis	33.20	9.00e-79	288.00
IUUC-Bta-012391	Bos taurus	94.58	0.00e+00	1074.00
IUUC-Cel-018495	Caenorhabditis elegans	47.75	4.00e-128	452.00
IUUC-Cja-018902	Callithrix jacchus	94.45	0.00e+00	1049.00
IUUC-Cfa-020237	Canis familiaris	94.45	0.00e+00	1048.00
IUUC-Cpo-022234	Cavia porcellus	94.58	0.00e+00	1075.00
IUUC-Cre-022837	Chlamydomonas reinhardtii	36.75	9.00e-48	184.00
IUUC-Csa-023532	Chlorocebus sabaeus	94.45	0.00e+00	1050.00
IUUC-Cho-025026	Choloepus hoffmanni	77.07	0.00e+00	690.00
IUUC-Cin-025516	Ciona intestinalis	70.34	2.00e-139	488.00
IUUC-Csv-026312	Ciona savignyi	71.09	0.00e+00	745.00
IUUC-Cgl-026492	Colletotrichum gloeosporioides	34.82	1.00e-84	307.00
IUUC-Cne-027018	Cryptococcus neoformans	33.02	1.00e-71	265.00
IUUC-Dre-028303	Danio rerio	92.98	0.00e+00	1037.00
IUUC-Dno-029576	Dasypus novemcinctus	91.77	0.00e+00	1032.00
IUUC-Dor-030196	Dipodomys ordii	91.83	0.00e+00	1026.00
IUUC-Dme-031702	Drosophila melanogaster	72.36	0.00e+00	790.00
IUUC-Ete-032791	Echinops telfairi	87.04	0.00e+00	963.00
IUUC-Eca-033424	Equus caballus	94.58	0.00e+00	1074.00
IUUC-Eeu-034996	Erinaceus europaeus	91.68	0.00e+00	1016.00
IUUC-Fca-036422	Felis catus	93.78	0.00e+00	1052.00
IUUC-Fal-037267	Ficedula albicollis	93.05	0.00e+00	1044.00
IUUC-Fox-037800	Fusarium oxysporum	33.87	2.00e-83	303.00
IUUC-Gmo-039119	Gadus morhua	87.52	0.00e+00	953.00
IUUC-Ggr-039781	Gaeumannomyces graminis	34.86	6.00e-85	308.00
IUUC-Gga-040667	Gallus gallus	93.77	0.00e+00	1051.00
IUUC-Ggo-044422	Gorilla gorilla	94.45	0.00e+00	1050.00
IUUC-Hsa-045898	Homo sapiens	94.45	0.00e+00	1050.00
IUUC-Itr-048241	Ictidomys tridecemlineatus	97.00	0.00e+00	942.00
IUUC-Kpa-049097	Komagataella pastoris	31.15	2.00e-74	273.00
IUUC-Lch-050414	Latimeria chalumnae	94.82	0.00e+00	1055.00
IUUC-Loc-052348	Lepisosteus oculatus	96.75	0.00e+00	1098.00
IUUC-Lma-053185	Leptosphaeria maculans	32.40	7.00e-73	269.00
IUUC-Laf-054054	Loxodonta africana	94.27	0.00e+00	1050.00
IUUC-Mcc-055056	Macaca mulatta	94.45	0.00e+00	1050.00
IUUC-Meu-056778	Macropus eugenii	89.91	9.00e-168	583.00
IUUC-Mor-057076	Magnaporthe oryzae	34.52	3.00e-84	306.00
IUUC-Mla-059081	Melampsora laricipopulina	33.33	3.00e-79	290.00
IUUC-Mga-059255	Meleagris gallopavo	93.60	0.00e+00	1050.00
IUUC-Mvi-060490	Microbotryum violaceum	38.75	1.00e-65	245.00
IUUC-Mmr-061292	Microcebus murinus	94.45	0.00e+00	1048.00
IUUC-Mdo-062304	Monodelphis domestica	94.15	0.00e+00	1056.00
IUUC-Mmu-063610	Mus musculus	93.28	0.00e+00	1051.00
IUUC-Mpu-065931	Mustela putorius furo	94.45	0.00e+00	1049.00
IUUC-Mlu-066976	Myotis lucifugus	93.10	0.00e+00	1052.00
IUUC-Nfi-068428	Neosartorya fischeri	31.33	2.00e-73	270.00
IUUC-Ncr-068688	Neurospora crassa	36.38	3.00e-88	319.00
IUUC-Nle-070174	Nomascus leucogenys	94.45	0.00e+00	1050.00
IUUC-Opr-070851	Ochotona princeps	79.21	6.00e-174	603.00
IUUC-Oan-072936	Ornithorhynchus anatinus	93.97	0.00e+00	1055.00
IUUC-Ocu-074742	Oryctolagus cuniculus	93.28	0.00e+00	1051.00
IUUC-Obr-076806	Oryza brachyantha	30.80	4.00e-28	120.00
IUUC-Oin-079809	Oryza indica	30.80	3.00e-28	121.00
IUUC-Ola-087098	Oryzias latipes	96.33	0.00e+00	1090.00
IUUC-Olu-087837	Ostreococcus lucimarinus	34.47	5.00e-38	151.00
IUUC-Oga-088884	Otolemur garnettii	96.83	0.00e+00	759.00
IUUC-Oar-090220	Ovis aries	93.76	0.00e+00	1045.00
IUUC-Ptr-090492	Pan troglodytes	94.45	0.00e+00	1050.00
IUUC-Pan-091770	Papio anubis	94.45	0.00e+00	1050.00
IUUC-Psi-093207	Pelodiscus sinensis	94.58	0.00e+00	1075.00
IUUC-Pma-094749	Petromyzon marinus	82.59	0.00e+00	956.00
IUUC-Pno-095026	Phaeosphaeria nodorum	39.10	9.00e-71	262.00
IUUC-Pfo-096493	Poecilia formosa	97.97	0.00e+00	1082.00
IUUC-Pab-098141	Pongo abelii	94.58	0.00e+00	1074.00
IUUC-Pca-100571	Procavia capensis	92.15	0.00e+00	731.00
IUUC-Pva-102988	Pteropus vampyrus	93.45	0.00e+00	1051.00
IUUC-Pgr-103612	Puccinia graminis	35.48	5.00e-61	229.00
IUUC-Rno-105706	Rattus norvegicus	93.60	0.00e+00	1049.00
IUUC-Sce-106314	Saccharomyces cerevisiae	30.18	1.00e-60	228.00
IUUC-Sha-107653	Sarcophilus harrisii	94.15	0.00e+00	1051.00
IUUC-Sja-107840	Schizosaccharomyces japonicus	34.02	8.00e-79	288.00
IUUC-Spo-108115	Schizosaccharomyces pombe	31.66	5.00e-62	232.00
IUUC-Sar-113600	Sorex araneus	87.80	0.00e+00	955.00
IUUC-Sre-114901	Sporisorium reilianum	46.89	2.00e-65	244.00
IUUC-Ssc-115787	Sus scrofa	91.47	0.00e+00	1021.00
IUUC-Tgu-117510	Taeniopygia guttata	93.59	0.00e+00	1048.00
IUUC-Tru-117819	Takifugu rubripes	98.71	0.00e+00	1110.00
IUUC-Tsy-118828	Tarsius syrichta	93.28	0.00e+00	1050.00
IUUC-Tni-120468	Tetraodon nigroviridis	98.55	0.00e+00	1127.00
IUUC-Tme-127021	Tuber melanosporum	35.29	4.00e-84	305.00
IUUC-Tbe-127925	Tupaia belangeri	94.44	0.00e+00	1048.00
IUUC-Ttr-128899	Tursiops truncatus	94.09	0.00e+00	1047.00
IUUC-Uma-129449	Ustilago maydis	45.64	2.00e-64	241.00
IUUC-Vpa-130082	Vicugna pacos	93.58	0.00e+00	872.00
IUUC-Xtr-132213	Xenopus tropicalis	94.82	0.00e+00	1052.00
IUUC-Xma-133646	Xiphophorus maculatus	97.83	0.00e+00	1103.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence