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Tag Content
iUUCD ID IUUC-Mdo-063001
Ensembl Protein ID ENSMODP00000001707.3
UniProt Accession F7BD34; F7BD34_MONDO
Protein Name DNA repair protein REV1
Gene Name REV1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMODG00000001409.3 ENSMODT00000001742.3 ENSMODP00000001707.3
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 3.20e-19 68.1 1019 1047
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
    ++sqvDpeVf++LP+e+QeE++a+++q++
   Q: 1019 AFSQVDPEVFAALPPELQEELKAAYEQRQ 1047
    59*************************98 PP
   

Organism Monodelphis domestica
Functional Description
(View)

Functional Description



     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MRRSGWRKRP ENDGWGKWGG YMAAKVQKLE EQFRSDAALQ KEGTPSTIFS GVAIYVNGYT 60
DPSAEELRKL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120
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Protein Fasta Sequence



>IUUC-Mdo-063001|UBD,UBM|Monodelphis domestica
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Nucleotide Sequence
(Fasta)
AAGAATATTA CCAAATTAAC ATTAATCCTT TTTTTTTCCT TATGCAGAAG CTCCAGTATG 60
AGGCGAAGTG GATGGAGGAA ACGACCTGAA AATGATGGCT GGGGGAAATG GGTATGTTTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mdo-063001|UBD,UBM|Monodelphis domestica
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 29.31 8.00e-31 129.00
IUUC-Aml-001185 Ailuropoda melanoleuca 82.30 0.00e+00 1991.00
IUUC-Atr-002915 Amborella trichopoda 35.36 8.00e-78 285.00
IUUC-Apl-004054 Anas platyrhynchos 78.30 0.00e+00 1873.00
IUUC-Aca-004304 Anolis carolinensis 70.65 0.00e+00 1724.00
IUUC-Aly-005696 Arabidopsis lyrata 34.79 5.00e-85 309.00
IUUC-Ath-006893 Arabidopsis thaliana 34.74 8.00e-86 311.00
IUUC-Ago-007722 Ashbya gossypii 31.88 9.00e-35 142.00
IUUC-Acl-008347 Aspergillus clavatus 37.10 2.00e-82 301.00
IUUC-Afl-008444 Aspergillus flavus 37.35 7.00e-86 312.00
IUUC-Afu-008837 Aspergillus fumigatus 31.51 2.00e-85 311.00
IUUC-Ani-009188 Aspergillus nidulans 37.70 4.00e-91 330.00
IUUC-Ang-009866 Aspergillus niger 35.17 1.00e-96 348.00
IUUC-Aor-010107 Aspergillus oryzae 37.35 1.00e-85 311.00
IUUC-Ate-010359 Aspergillus terreus 32.26 4.00e-90 326.00
IUUC-Ame-010664 Astyanax mexicanus 55.19 0.00e+00 942.00
IUUC-Bgr-012244 Blumeria graminis 29.29 2.00e-83 303.00
IUUC-Bta-013405 Bos taurus 75.31 0.00e+00 1685.00
IUUC-Bci-013849 Botrytis cinerea 30.63 4.00e-85 310.00
IUUC-Bdi-014066 Brachypodium distachyon 36.36 2.00e-80 294.00
IUUC-Bol-015544 Brassica oleracea 36.04 2.00e-88 321.00
IUUC-Bra-017792 Brassica rapa 35.77 6.00e-83 302.00
IUUC-Cel-018148 Caenorhabditis elegans 32.13 2.00e-75 277.00
IUUC-Cja-019742 Callithrix jacchus 71.95 0.00e+00 1416.00
IUUC-Cfa-020112 Canis familiaris 82.78 0.00e+00 2021.00
IUUC-Cpo-022152 Cavia porcellus 77.92 0.00e+00 1940.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 43.95 3.00e-39 156.00
IUUC-Csa-023504 Chlorocebus sabaeus 82.76 0.00e+00 2008.00
IUUC-Cho-024780 Choloepus hoffmanni 62.96 0.00e+00 699.00
IUUC-Cin-025276 Ciona intestinalis 53.00 1.00e-102 367.00
IUUC-Csv-026283 Ciona savignyi 44.22 2.00e-115 409.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 27.93 3.00e-89 323.00
IUUC-Cne-027079 Cryptococcus neoformans 34.05 5.00e-78 286.00
IUUC-Cme-027346 Cyanidioschyzon merolae 30.52 2.00e-37 151.00
IUUC-Dre-028073 Danio rerio 50.64 0.00e+00 1121.00
IUUC-Dno-030038 Dasypus novemcinctus 79.60 0.00e+00 1935.00
IUUC-Dor-031100 Dipodomys ordii 77.73 0.00e+00 1401.00
IUUC-Dse-031310 Dothistroma septosporum 32.71 4.00e-78 286.00
IUUC-Dme-031991 Drosophila melanogaster 41.40 4.00e-111 396.00
IUUC-Ete-033082 Echinops telfairi 73.33 0.00e+00 1318.00
IUUC-Eca-033471 Equus caballus 82.47 0.00e+00 1999.00
IUUC-Eeu-034993 Erinaceus europaeus 81.71 0.00e+00 1346.00
IUUC-Fca-035367 Felis catus 82.11 0.00e+00 1935.00
IUUC-Fal-036973 Ficedula albicollis 77.09 0.00e+00 1791.00
IUUC-Fox-037677 Fusarium oxysporum 33.39 5.00e-82 299.00
IUUC-Fso-038252 Fusarium solani 34.94 2.00e-83 304.00
IUUC-Gmo-039669 Gadus morhua 53.55 0.00e+00 847.00
IUUC-Ggr-039988 Gaeumannomyces graminis 36.06 5.00e-85 309.00
IUUC-Gga-040423 Gallus gallus 78.09 0.00e+00 1856.00
IUUC-Gac-042134 Gasterosteus aculeatus 53.86 0.00e+00 836.00
IUUC-Gma-042929 Glycine max 32.37 9.00e-91 328.00
IUUC-Ggo-044528 Gorilla gorilla 82.84 0.00e+00 2008.00
IUUC-Hsa-046259 Homo sapiens 82.92 0.00e+00 1991.00
IUUC-Hvu-047139 Hordeum vulgare 35.31 3.00e-53 202.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 81.19 0.00e+00 1979.00
IUUC-Kpa-049169 Komagataella pastoris 29.96 3.00e-63 237.00
IUUC-Lch-050471 Latimeria chalumnae 66.43 0.00e+00 1557.00
IUUC-Lpe-050800 Leersia perrieri 30.00 9.00e-90 325.00
IUUC-Loc-052320 Lepisosteus oculatus 47.59 0.00e+00 927.00
IUUC-Lma-053149 Leptosphaeria maculans 28.30 5.00e-81 296.00
IUUC-Laf-053810 Loxodonta africana 78.83 0.00e+00 1859.00
IUUC-Mcc-055574 Macaca mulatta 82.92 0.00e+00 1974.00
IUUC-Meu-055945 Macropus eugenii 76.19 0.00e+00 1351.00
IUUC-Mor-057195 Magnaporthe oryzae 30.37 7.00e-91 329.00
IUUC-Mpo-057488 Magnaporthe poae 34.83 7.00e-85 309.00
IUUC-Mtr-057955 Medicago truncatula 35.86 3.00e-91 330.00
IUUC-Mla-059027 Melampsora laricipopulina 36.91 1.00e-82 301.00
IUUC-Mga-060156 Meleagris gallopavo 77.94 0.00e+00 1862.00
IUUC-Mvi-060398 Microbotryum violaceum 35.79 8.00e-82 299.00
IUUC-Mmr-061113 Microcebus murinus 83.10 0.00e+00 1993.00
IUUC-Mmu-063180 Mus musculus 77.80 0.00e+00 1873.00
IUUC-Mac-065551 Musa acuminata 38.87 5.00e-54 205.00
IUUC-Mpu-066525 Mustela putorius furo 82.70 0.00e+00 1998.00
IUUC-Mlu-067877 Myotis lucifugus 81.99 0.00e+00 1960.00
IUUC-Nfi-068418 Neosartorya fischeri 32.18 2.00e-87 317.00
IUUC-Ncr-068648 Neurospora crassa 32.34 3.00e-89 324.00
IUUC-Nle-069959 Nomascus leucogenys 82.84 0.00e+00 1992.00
IUUC-Opr-070522 Ochotona princeps 77.91 0.00e+00 1118.00
IUUC-Ont-072293 Oreochromis niloticus 50.88 0.00e+00 843.00
IUUC-Oan-073519 Ornithorhynchus anatinus 80.79 0.00e+00 1977.00
IUUC-Ocu-074492 Oryctolagus cuniculus 78.94 0.00e+00 1810.00
IUUC-Oba-075567 Oryza barthii 30.17 2.00e-90 327.00
IUUC-Obr-076332 Oryza brachyantha 37.81 4.00e-87 316.00
IUUC-Ogl-077348 Oryza glaberrima 28.66 2.00e-90 327.00
IUUC-Ogu-078779 Oryza glumaepatula 30.05 3.00e-90 326.00
IUUC-Oin-079738 Oryza indica 27.15 1.00e-78 288.00
IUUC-Olo-080701 Oryza longistaminata 30.07 1.00e-78 288.00
IUUC-Ome-081708 Oryza meridionalis 32.32 1.00e-87 318.00
IUUC-Oni-082251 Oryza nivara 29.93 8.00e-88 318.00
IUUC-Opu-083528 Oryza punctata 32.74 3.00e-82 300.00
IUUC-Oru-084293 Oryza rufipogon 29.56 3.00e-85 310.00
IUUC-Osa-085549 Oryza sativa 28.66 3.00e-90 327.00
IUUC-Ola-086793 Oryzias latipes 50.05 0.00e+00 866.00
IUUC-Olu-087786 Ostreococcus lucimarinus 28.18 1.00e-59 224.00
IUUC-Oga-089006 Otolemur garnettii 81.93 0.00e+00 1966.00
IUUC-Oar-089597 Ovis aries 77.02 0.00e+00 1847.00
IUUC-Ptr-091520 Pan troglodytes 82.76 0.00e+00 1986.00
IUUC-Pan-092333 Papio anubis 83.00 0.00e+00 1964.00
IUUC-Psi-094004 Pelodiscus sinensis 80.87 0.00e+00 1957.00
IUUC-Pma-094128 Petromyzon marinus 52.72 1.00e-93 337.00
IUUC-Pno-094849 Phaeosphaeria nodorum 28.57 3.00e-76 280.00
IUUC-Ppa-095714 Physcomitrella patens 44.31 1.00e-81 298.00
IUUC-Pfo-096569 Poecilia formosa 53.28 0.00e+00 844.00
IUUC-Pab-097960 Pongo abelii 82.68 0.00e+00 1983.00
IUUC-Pop-098921 Populus trichocarpa 35.92 3.00e-83 303.00
IUUC-Pca-100509 Procavia capensis 66.53 0.00e+00 1141.00
IUUC-Ppe-101730 Prunus persica 33.93 2.00e-83 303.00
IUUC-Pva-102142 Pteropus vampyrus 80.14 0.00e+00 1931.00
IUUC-Pgr-103446 Puccinia graminis 31.55 5.00e-71 262.00
IUUC-Ptt-103849 Puccinia triticina 31.24 1.00e-75 279.00
IUUC-Pte-104128 Pyrenophora teres 29.43 9.00e-77 282.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 41.72 6.00e-72 265.00
IUUC-Rno-104871 Rattus norvegicus 75.50 0.00e+00 1844.00
IUUC-Sce-106236 Saccharomyces cerevisiae 27.50 7.00e-41 162.00
IUUC-Sha-106962 Sarcophilus harrisii 92.56 0.00e+00 2234.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 34.02 7.00e-65 242.00
IUUC-Spo-108170 Schizosaccharomyces pombe 33.26 4.00e-63 236.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 34.89 2.00e-85 310.00
IUUC-Smo-109554 Selaginella moellendorffii 36.85 9.00e-86 312.00
IUUC-Sit-110479 Setaria italica 42.72 3.00e-71 263.00
IUUC-Sly-111752 Solanum lycopersicum 35.38 5.00e-84 306.00
IUUC-Sar-113304 Sorex araneus 80.74 0.00e+00 1890.00
IUUC-Sbi-114196 Sorghum bicolor 42.72 1.00e-72 268.00
IUUC-Sre-115151 Sporisorium reilianum 32.47 3.00e-86 313.00
IUUC-Ssc-116104 Sus scrofa 80.89 0.00e+00 1952.00
IUUC-Tgu-117438 Taeniopygia guttata 78.61 0.00e+00 1855.00
IUUC-Tru-118553 Takifugu rubripes 48.85 0.00e+00 999.00
IUUC-Tsy-119056 Tarsius syrichta 78.68 0.00e+00 1844.00
IUUC-Tni-119933 Tetraodon nigroviridis 47.64 0.00e+00 981.00
IUUC-Tca-121376 Theobroma cacao 31.25 3.00e-86 313.00
IUUC-Tre-121972 Trichoderma reesei 27.77 7.00e-83 302.00
IUUC-Tvi-122342 Trichoderma virens 35.18 2.00e-78 287.00
IUUC-Tae-123898 Triticum aestivum 32.93 7.00e-84 305.00
IUUC-Tur-126735 Triticum urartu 31.55 2.00e-36 148.00
IUUC-Tme-126999 Tuber melanosporum 33.53 5.00e-81 296.00
IUUC-Tbe-127280 Tupaia belangeri 77.22 3.00e-115 410.00
IUUC-Ttr-129104 Tursiops truncatus 79.95 0.00e+00 1919.00
IUUC-Uma-129562 Ustilago maydis 30.17 1.00e-85 311.00
IUUC-Vda-129862 Verticillium dahliae 32.92 2.00e-78 288.00
IUUC-Vpa-130819 Vicugna pacos 80.18 0.00e+00 1042.00
IUUC-Vvi-131111 Vitis vinifera 34.99 1.00e-86 315.00
IUUC-Xtr-132629 Xenopus tropicalis 62.91 0.00e+00 1441.00
IUUC-Xma-134065 Xiphophorus maculatus 52.35 0.00e+00 828.00
IUUC-Yli-134633 Yarrowia lipolytica 33.33 1.00e-61 232.00
IUUC-Zma-135176 Zea mays 36.65 2.00e-87 317.00
Created Date 25-Jun-2017

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