iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117190

Ensembl Protein ID

ENSTGUP00000002252.1

UniProt Accession

H0YVD1; H0YVD1_TAEGU

Genbank Protein ID

ENSTGUP00000002252

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

ABQF01020819

Gene Name

PRKAA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000002173.1	ENSTGUT00000002272.1	ENSTGUP00000002252.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	49.90	4.00e-115	412.00	IUUC-Ath-007014
UBD/Alpha-Helix/UBA	40.35	4.00e-98	353.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MRRLGPCLKM AAVADKQKHE HGRVKIGHYI LGDTLGVGTF GKVKVGKHEL TGHKVAVKIL 60
NRQKIRSLDV VGKIRREIQN LKLFRHPHII KLYQVISTPT DIFMVMEYVS GGELFDYICK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGCAGGC TCGGCCCTTG CCTCAAGATG GCGGCGGTGG CGGATAAACA GAAGCACGAG 60
CACGGCCGGG TGAAGATTGG GCATTATATC CTGGGCGACA CGCTGGGCGT CGGCACCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005623--C:cell
GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0061762--P:CAMKK-AMPK signaling cascade
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0019395--P:fatty acid oxidation
GO:0042593--P:glucose homeostasis
GO:0006006--P:glucose metabolic process
GO:0031649--P:heat generation
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0050995--P:negative regulation of lipid catabolic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0010628--P:positive regulation of gene expression
GO:0048643--P:positive regulation of skeletal muscle tissue development
GO:0042752--P:regulation of circadian rhythm
GO:0033135--P:regulation of peptidyl-serine phosphorylation
GO:1904101--P:response to acadesine
GO:1901563--P:response to camptothecin
GO:0010332--P:response to gamma radiation
GO:0042542--P:response to hydrogen peroxide
GO:0009411--P:response to UV

KEGG

tgu:100217569

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000134	Aegilops tauschii	49.01	7.00e-115	407.00
IUUC-Aml-001907	Ailuropoda melanoleuca	93.24	0.00e+00	999.00
IUUC-Atr-002770	Amborella trichopoda	48.07	2.00e-124	439.00
IUUC-Apl-003395	Anas platyrhynchos	74.57	0.00e+00	794.00
IUUC-Aca-004480	Anolis carolinensis	79.35	0.00e+00	809.00
IUUC-Aly-006289	Arabidopsis lyrata	50.21	4.00e-123	434.00
IUUC-Ath-007014	Arabidopsis thaliana	50.64	2.00e-125	441.00
IUUC-Ago-007957	Ashbya gossypii	41.50	4.00e-113	401.00
IUUC-Acl-008103	Aspergillus clavatus	59.71	2.00e-99	356.00
IUUC-Afl-008555	Aspergillus flavus	58.99	9.00e-100	357.00
IUUC-Afu-008949	Aspergillus fumigatus	59.35	2.00e-99	356.00
IUUC-Ani-009408	Aspergillus nidulans	60.00	8.00e-100	357.00
IUUC-Ang-009551	Aspergillus niger	59.71	1.00e-100	360.00
IUUC-Aor-010176	Aspergillus oryzae	58.99	7.00e-100	357.00
IUUC-Ate-010287	Aspergillus terreus	59.35	3.00e-99	355.00
IUUC-Ame-011019	Astyanax mexicanus	73.80	0.00e+00	828.00
IUUC-Bgr-012045	Blumeria graminis	58.27	3.00e-99	355.00
IUUC-Bta-012786	Bos taurus	92.88	0.00e+00	998.00
IUUC-Bci-013774	Botrytis cinerea	45.05	3.00e-101	362.00
IUUC-Bdi-014319	Brachypodium distachyon	47.59	6.00e-121	427.00
IUUC-Bol-016242	Brassica oleracea	51.64	1.00e-125	442.00
IUUC-Bra-016750	Brassica rapa	52.72	4.00e-126	444.00
IUUC-Cel-018518	Caenorhabditis elegans	57.79	1.00e-179	622.00
IUUC-Cja-019386	Callithrix jacchus	74.77	0.00e+00	845.00
IUUC-Cfa-020177	Canis familiaris	94.22	0.00e+00	967.00
IUUC-Cpo-021805	Cavia porcellus	74.77	0.00e+00	843.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	55.76	2.00e-95	342.00
IUUC-Csa-024267	Chlorocebus sabaeus	74.95	0.00e+00	843.00
IUUC-Cho-024859	Choloepus hoffmanni	91.73	0.00e+00	954.00
IUUC-Cin-025550	Ciona intestinalis	59.16	0.00e+00	658.00
IUUC-Csv-026139	Ciona savignyi	57.50	0.00e+00	664.00
IUUC-Cne-027044	Cryptococcus neoformans	47.03	1.00e-104	373.00
IUUC-Cme-027289	Cyanidioschyzon merolae	46.67	2.00e-112	399.00
IUUC-Dre-027749	Danio rerio	84.99	0.00e+00	950.00
IUUC-Dno-030006	Dasypus novemcinctus	93.24	0.00e+00	996.00
IUUC-Dor-030578	Dipodomys ordii	74.77	0.00e+00	842.00
IUUC-Dse-031507	Dothistroma septosporum	62.31	6.00e-104	371.00
IUUC-Dme-031704	Drosophila melanogaster	56.45	4.00e-176	610.00
IUUC-Ete-033055	Echinops telfairi	90.64	0.00e+00	1013.00
IUUC-Eca-034239	Equus caballus	94.40	0.00e+00	966.00
IUUC-Fca-035754	Felis catus	91.87	0.00e+00	983.00
IUUC-Fal-037363	Ficedula albicollis	99.11	0.00e+00	1050.00
IUUC-Fox-038073	Fusarium oxysporum	58.60	4.00e-101	362.00
IUUC-Fso-038236	Fusarium solani	57.89	1.00e-97	350.00
IUUC-Gmo-039633	Gadus morhua	81.27	0.00e+00	964.00
IUUC-Ggr-039987	Gaeumannomyces graminis	49.86	6.00e-101	361.00
IUUC-Gga-040546	Gallus gallus	75.09	0.00e+00	845.00
IUUC-Gac-041822	Gasterosteus aculeatus	72.76	0.00e+00	796.00
IUUC-Gma-042712	Glycine max	48.04	8.00e-125	440.00
IUUC-Ggo-044797	Gorilla gorilla	93.42	0.00e+00	999.00
IUUC-Hsa-045867	Homo sapiens	93.24	0.00e+00	998.00
IUUC-Hvu-047406	Hordeum vulgare	46.90	2.00e-121	428.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	74.95	0.00e+00	847.00
IUUC-Kpa-049190	Komagataella pastoris	42.38	1.00e-116	413.00
IUUC-Lch-049623	Latimeria chalumnae	88.59	0.00e+00	943.00
IUUC-Lpe-051392	Leersia perrieri	52.71	2.00e-125	442.00
IUUC-Loc-052362	Lepisosteus oculatus	91.98	0.00e+00	926.00
IUUC-Lma-053054	Leptosphaeria maculans	50.00	1.00e-106	380.00
IUUC-Laf-053799	Loxodonta africana	93.06	0.00e+00	1030.00
IUUC-Mcc-055862	Macaca mulatta	74.95	0.00e+00	848.00
IUUC-Mor-057170	Magnaporthe oryzae	59.64	1.00e-101	363.00
IUUC-Mpo-057302	Magnaporthe poae	49.86	4.00e-101	362.00
IUUC-Mtr-058236	Medicago truncatula	52.83	4.00e-124	437.00
IUUC-Mla-059058	Melampsora laricipopulina	42.48	3.00e-102	365.00
IUUC-Mga-059206	Meleagris gallopavo	75.10	0.00e+00	793.00
IUUC-Mvi-060337	Microbotryum violaceum	50.28	6.00e-100	358.00
IUUC-Mmr-061761	Microcebus murinus	93.06	0.00e+00	996.00
IUUC-Mdo-062160	Monodelphis domestica	75.04	0.00e+00	839.00
IUUC-Mmu-063406	Mus musculus	73.87	0.00e+00	838.00
IUUC-Mac-064518	Musa acuminata	50.00	1.00e-117	416.00
IUUC-Mpu-066326	Mustela putorius furo	74.57	0.00e+00	792.00
IUUC-Mlu-068227	Myotis lucifugus	94.21	0.00e+00	964.00
IUUC-Nfi-068493	Neosartorya fischeri	59.35	1.00e-99	357.00
IUUC-Ncr-068665	Neurospora crassa	41.41	5.00e-105	374.00
IUUC-Nle-070158	Nomascus leucogenys	74.95	0.00e+00	849.00
IUUC-Opr-070272	Ochotona princeps	90.12	0.00e+00	981.00
IUUC-Ont-072027	Oreochromis niloticus	82.21	0.00e+00	932.00
IUUC-Oan-073322	Ornithorhynchus anatinus	91.11	0.00e+00	954.00
IUUC-Ocu-074188	Oryctolagus cuniculus	91.33	0.00e+00	976.00
IUUC-Oba-075436	Oryza barthii	48.24	6.00e-126	444.00
IUUC-Obr-076507	Oryza brachyantha	48.57	6.00e-127	447.00
IUUC-Ogl-077718	Oryza glaberrima	48.37	1.00e-122	432.00
IUUC-Ogu-078349	Oryza glumaepatula	48.24	8.00e-126	443.00
IUUC-Oin-079889	Oryza indica	48.05	3.00e-123	435.00
IUUC-Olo-080521	Oryza longistaminata	48.24	6.00e-126	443.00
IUUC-Ome-081630	Oryza meridionalis	48.03	1.00e-125	442.00
IUUC-Oni-082211	Oryza nivara	48.24	3.00e-126	445.00
IUUC-Opu-083617	Oryza punctata	48.14	2.00e-125	442.00
IUUC-Oru-084252	Oryza rufipogon	48.24	5.00e-126	444.00
IUUC-Osa-085548	Oryza sativa	48.24	5.00e-126	444.00
IUUC-Ola-086366	Oryzias latipes	85.25	0.00e+00	957.00
IUUC-Olu-087861	Ostreococcus lucimarinus	50.47	2.00e-117	415.00
IUUC-Oga-088003	Otolemur garnettii	93.24	0.00e+00	998.00
IUUC-Oar-089933	Ovis aries	92.88	0.00e+00	998.00
IUUC-Ptr-090718	Pan troglodytes	93.24	0.00e+00	998.00
IUUC-Pan-092526	Papio anubis	93.42	0.00e+00	999.00
IUUC-Psi-094034	Pelodiscus sinensis	96.26	0.00e+00	1019.00
IUUC-Pno-095030	Phaeosphaeria nodorum	59.17	5.00e-105	374.00
IUUC-Ppa-095615	Physcomitrella patens	51.61	6.00e-123	434.00
IUUC-Pfo-097050	Poecilia formosa	83.72	0.00e+00	936.00
IUUC-Pab-098519	Pongo abelii	93.24	0.00e+00	998.00
IUUC-Pop-099781	Populus trichocarpa	54.01	5.00e-126	444.00
IUUC-Pca-101104	Procavia capensis	92.58	0.00e+00	733.00
IUUC-Ppe-101642	Prunus persica	49.16	5.00e-123	434.00
IUUC-Pva-102470	Pteropus vampyrus	74.77	0.00e+00	838.00
IUUC-Pgr-103406	Puccinia graminis	59.34	9.00e-91	327.00
IUUC-Ptt-103713	Puccinia triticina	49.15	2.00e-72	266.00
IUUC-Pte-104259	Pyrenophora teres	55.84	6.00e-105	374.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	56.25	2.00e-105	376.00
IUUC-Rno-104960	Rattus norvegicus	74.41	0.00e+00	843.00
IUUC-Sce-106290	Saccharomyces cerevisiae	40.67	7.00e-112	397.00
IUUC-Sha-107603	Sarcophilus harrisii	93.77	0.00e+00	998.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	52.57	3.00e-109	388.00
IUUC-Spo-108202	Schizosaccharomyces pombe	40.35	3.00e-107	382.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	45.54	3.00e-99	355.00
IUUC-Smo-109309	Selaginella moellendorffii	46.45	1.00e-122	432.00
IUUC-Sit-109745	Setaria italica	49.17	1.00e-126	446.00
IUUC-Sly-110890	Solanum lycopersicum	52.69	1.00e-123	436.00
IUUC-Stu-112144	Solanum tuberosum	46.17	2.00e-116	412.00
IUUC-Sar-113521	Sorex araneus	84.91	0.00e+00	835.00
IUUC-Sbi-114764	Sorghum bicolor	48.36	1.00e-127	449.00
IUUC-Sre-115141	Sporisorium reilianum	66.18	1.00e-112	400.00
IUUC-Ssc-115732	Sus scrofa	94.21	0.00e+00	964.00
IUUC-Tru-118735	Takifugu rubripes	72.58	0.00e+00	814.00
IUUC-Tsy-119503	Tarsius syrichta	71.65	0.00e+00	747.00
IUUC-Tni-119833	Tetraodon nigroviridis	83.45	0.00e+00	944.00
IUUC-Tca-121386	Theobroma cacao	48.57	2.00e-125	441.00
IUUC-Tre-122070	Trichoderma reesei	51.24	2.00e-103	369.00
IUUC-Tvi-122305	Trichoderma virens	57.24	2.00e-101	363.00
IUUC-Tae-123515	Triticum aestivum	52.80	7.00e-126	443.00
IUUC-Tur-126416	Triticum urartu	46.60	8.00e-121	427.00
IUUC-Tme-127174	Tuber melanosporum	41.54	3.00e-68	252.00
IUUC-Tbe-127791	Tupaia belangeri	77.39	4.00e-102	364.00
IUUC-Ttr-129224	Tursiops truncatus	90.64	0.00e+00	990.00
IUUC-Uma-129372	Ustilago maydis	66.18	1.00e-111	397.00
IUUC-Vda-129819	Verticillium dahliae	53.33	3.00e-85	308.00
IUUC-Vpa-130220	Vicugna pacos	74.14	0.00e+00	785.00
IUUC-Vvi-131649	Vitis vinifera	47.96	3.00e-124	437.00
IUUC-Xtr-132954	Xenopus tropicalis	74.82	0.00e+00	843.00
IUUC-Xma-134082	Xiphophorus maculatus	91.26	0.00e+00	862.00
IUUC-Yli-134422	Yarrowia lipolytica	43.63	2.00e-116	412.00
IUUC-Zma-135621	Zea mays	55.24	5.00e-120	424.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence