iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088305

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03001557

Gene Name

TRIM5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000016982.2	ENSOGAT00000016987.2	ENSOGAP00000015207.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.10e-09	36.1	15	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle + + pl+l+CgH f++ C+ ++ + +   + ++ +CP Cr
   Q: 15   CPICLELLIE-PLSLDCGHSFCQACIsENQKKSTIDQEGQSSCPMCR 60
           **********.***************94555799999*********8 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MDSELLLNMK EEVTCPICLE LLIEPLSLDC GHSFCQACIS ENQKKSTIDQ EGQSSCPMCR 60
ITYQFENLRP NRPLANIVER LRGITLNSEE GQKVDHCEHH GEKLLLFCEE DGEVICWLCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTCAG AACTCCTGCT GAATATGAAG GAGGAGGTGA CCTGCCCCAT CTGCCTGGAA 60
CTCCTTATAG AGCCCCTGAG CCTAGACTGT GGCCACAGCT TCTGCCAAGC CTGCATCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR010908--Longin_dom
IPR032917--TRIM5
IPR000315--Znf_B-box
IPR020457--Znf_B-box_chordata
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box

PRINTS

PR01406--BBOXZNFINGER
PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:1990462--C:omegasome
GO:0000932--C:P-body
GO:0008329--F:signaling pattern recognition receptor activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0051607--P:defense response to virus
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043410--P:positive regulation of MAPK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0070534--P:protein K63-linked ubiquitination
GO:0031664--P:regulation of lipopolysaccharide-mediated signaling pathway
GO:0032880--P:regulation of protein localization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006134	Arabidopsis lyrata	35.85	6.00e-07	48.10
IUUC-Acl-008013	Aspergillus clavatus	54.05	4.00e-06	47.00
IUUC-Kpa-049392	Komagataella pastoris	40.51	5.00e-10	58.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence