iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013248

Ensembl Protein ID

ENSBTAP00000029334.5

UniProt Accession

F1MC50; F1MC50_BOVIN

Genbank Protein ID

ENSBTAP00000029334

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02031675

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000023172.4	ENSBTAT00000029334.5	ENSBTAP00000029334.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-60	200.6	1113	1165

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy+a+n+deL++ kG  + v+  ++ d +W++g  e++g  GlfP+n+v+ 
   Q: 1113 QVIAMYDYTANNEDELSFSKGQLINVL--NKDDPDWWQG--ETSGVTGLFPSNYVKM 1165
           6899***********************..8889******..9*************85 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

KASGPYLVLG GPNMWAITSE ERTKHDKQFD NLKPSGGYIT GDQARTFFLQ SGLPAPVLAE 60
IWALSDLNKD GKMDQQEFSI AMKLIKLKLQ GQQLPVVLPP IMKQPPMFSP LISARFGMGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGCGTCAG GACCATACTT GGTATGGTTA TGAATAGAGC TTTCTTCTTT GTGTCACTCC 60
AGTATTAGGA CTGTCATTAA AGGAGCATTT GTGATTCATG TTTACATTCT GGAATTGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	92.16	0.00e+00	2141.00
IUUC-Apl-004205	Anas platyrhynchos	78.80	0.00e+00	2432.00
IUUC-Aca-004287	Anolis carolinensis	78.62	0.00e+00	1654.00
IUUC-Ame-011759	Astyanax mexicanus	64.85	0.00e+00	1243.00
IUUC-Cel-018490	Caenorhabditis elegans	31.31	3.00e-53	204.00
IUUC-Cfa-020628	Canis familiaris	92.16	0.00e+00	2162.00
IUUC-Cpo-022427	Cavia porcellus	79.57	0.00e+00	2573.00
IUUC-Csa-023122	Chlorocebus sabaeus	92.25	0.00e+00	2115.00
IUUC-Cgl-026697	Colletotrichum gloeosporioides	28.46	1.00e-08	56.20
IUUC-Cne-026918	Cryptococcus neoformans	36.92	2.00e-38	155.00
IUUC-Dre-027849	Danio rerio	64.52	0.00e+00	1206.00
IUUC-Dno-029419	Dasypus novemcinctus	91.99	0.00e+00	2134.00
IUUC-Dor-030504	Dipodomys ordii	76.73	0.00e+00	1709.00
IUUC-Dme-032099	Drosophila melanogaster	33.70	6.00e-58	219.00
IUUC-Eca-034196	Equus caballus	89.62	0.00e+00	2038.00
IUUC-Eeu-034972	Erinaceus europaeus	66.95	1.00e-179	624.00
IUUC-Fca-035757	Felis catus	92.15	0.00e+00	2155.00
IUUC-Fal-037531	Ficedula albicollis	86.34	0.00e+00	1711.00
IUUC-Gga-041012	Gallus gallus	78.59	0.00e+00	1877.00
IUUC-Gac-041320	Gasterosteus aculeatus	53.91	0.00e+00	1266.00
IUUC-Ggo-045405	Gorilla gorilla	89.36	0.00e+00	2646.00
IUUC-Hsa-046833	Homo sapiens	91.68	0.00e+00	2099.00
IUUC-Kpa-049215	Komagataella pastoris	36.17	8.00e-15	75.10
IUUC-Lch-050094	Latimeria chalumnae	72.30	0.00e+00	1676.00
IUUC-Loc-052646	Lepisosteus oculatus	70.11	0.00e+00	1427.00
IUUC-Laf-053798	Loxodonta africana	86.38	0.00e+00	1394.00
IUUC-Mcc-054709	Macaca mulatta	91.27	0.00e+00	2119.00
IUUC-Meu-056396	Macropus eugenii	79.12	0.00e+00	1527.00
IUUC-Mla-059128	Melampsora laricipopulina	33.57	2.00e-40	162.00
IUUC-Mga-059997	Meleagris gallopavo	82.57	0.00e+00	2000.00
IUUC-Mvi-060268	Microbotryum violaceum	31.23	3.00e-45	178.00
IUUC-Mmr-060891	Microcebus murinus	93.15	0.00e+00	2158.00
IUUC-Mmu-064226	Mus musculus	87.08	0.00e+00	2122.00
IUUC-Mpu-066431	Mustela putorius furo	93.23	0.00e+00	2147.00
IUUC-Mlu-068190	Myotis lucifugus	90.69	0.00e+00	2125.00
IUUC-Nle-070116	Nomascus leucogenys	89.01	0.00e+00	1660.00
IUUC-Opr-070815	Ochotona princeps	79.42	0.00e+00	1745.00
IUUC-Ont-072464	Oreochromis niloticus	64.63	0.00e+00	1231.00
IUUC-Ocu-073856	Oryctolagus cuniculus	76.86	0.00e+00	1844.00
IUUC-Ola-087489	Oryzias latipes	53.09	0.00e+00	1265.00
IUUC-Oga-088449	Otolemur garnettii	89.86	0.00e+00	2070.00
IUUC-Oar-090275	Ovis aries	98.76	0.00e+00	2226.00
IUUC-Ptr-091667	Pan troglodytes	91.35	0.00e+00	2082.00
IUUC-Pan-091723	Papio anubis	89.13	0.00e+00	1794.00
IUUC-Psi-093136	Pelodiscus sinensis	81.22	0.00e+00	1925.00
IUUC-Pfo-096864	Poecilia formosa	53.41	0.00e+00	1593.00
IUUC-Pab-098755	Pongo abelii	89.07	0.00e+00	2019.00
IUUC-Pca-101134	Procavia capensis	84.33	0.00e+00	1474.00
IUUC-Pva-102433	Pteropus vampyrus	83.96	0.00e+00	1889.00
IUUC-Pgr-103473	Puccinia graminis	30.86	7.00e-40	160.00
IUUC-Ptt-103973	Puccinia triticina	26.05	8.00e-29	123.00
IUUC-Rno-105691	Rattus norvegicus	91.25	0.00e+00	2174.00
IUUC-Sar-112978	Sorex araneus	87.98	0.00e+00	1383.00
IUUC-Sre-115028	Sporisorium reilianum	33.33	1.00e-33	140.00
IUUC-Ssc-115562	Sus scrofa	85.95	0.00e+00	1962.00
IUUC-Tgu-116758	Taeniopygia guttata	81.91	0.00e+00	1979.00
IUUC-Tru-117714	Takifugu rubripes	63.85	0.00e+00	1212.00
IUUC-Tni-119958	Tetraodon nigroviridis	55.88	0.00e+00	1687.00
IUUC-Tbe-127477	Tupaia belangeri	88.25	0.00e+00	733.00
IUUC-Ttr-129196	Tursiops truncatus	92.87	0.00e+00	2092.00
IUUC-Vpa-130035	Vicugna pacos	81.48	0.00e+00	639.00
IUUC-Xma-133300	Xiphophorus maculatus	57.91	0.00e+00	1295.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence