iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049685

Ensembl Protein ID

ENSLACP00000012875.1

UniProt Accession

H3ATA4; H3ATA4_LATCH

Genbank Protein ID

ENSLACP00000012875

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AFYH01085089

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000011335.1	ENSLACT00000012969.1	ENSLACP00000012875.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	7.40e-64	216.4	4	228

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqv 94
           ++wl+Le++P++++++++++g+ + +q+ ++y++dpe l+++++pv+++lllF+++ek+e+++ +  + ++++++++++ +t++f+kq+
   Q: 4    QRWLPLEANPDVMNQFLSQLGILDSWQFVDVYGMDPELLSMVPRPVCAVLLLFPVTEKYEAFKLE--EEAKIKSQGQEVSSTVYFMKQT 90
           79************************************************************954..46789***************** PP
   S: 95   igNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvs 182
           i+N+C+t++l++++ n+ +kl ++  + ++++++++ + spe++a+ l++++ ++++h+s a++++++ p+ +       +k  +hf++
   Q: 91   ISNACGTIGLIHAVTNNRNKLqFEPDSAMKKFLDESSSLSPEERAKYLEKDESIRVTHESSAQEGQTETPSID-------EKVDLHFIT 172
           **********************************************************************888.......8899***** PP
   S: 183  yvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaiv 242
           +vn+ g+lyeldg+kpfP+++g +++++ l+d+++ +++f++r    + +e+rf+++a++
   Q: 173  FVNVSGHLYELDGRKPFPINHGCTSNETLLEDAIEICKKFMQR----DPEELRFTVVALS 228
           *******************************************....9********9986 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MECQRWLPLE ANPDVMNQFL SQLGILDSWQ FVDVYGMDPE LLSMVPRPVC AVLLLFPVTE 60
KYEAFKLEEE AKIKSQGQEV SSTVYFMKQT ISNACGTIGL IHAVTNNRNK LQFEPDSAMK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCCCTAGG TAGAATTGCA ATCTGCACTG AGTTCTCCCT CAAGTCTCCC CCTCCCCCCC 60
CATCATCATC ATCATCATCA TCATCATCAT CATCATCATC ATCTTGCTTG TGAAGAGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007219--P:Notch signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

lcm:102363406

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	42.80	5.00e-53	200.00
IUUC-Aml-001344	Ailuropoda melanoleuca	78.51	5.00e-110	389.00
IUUC-Atr-002931	Amborella trichopoda	43.78	2.00e-47	182.00
IUUC-Apl-003949	Anas platyrhynchos	76.78	1.00e-92	332.00
IUUC-Aca-004924	Anolis carolinensis	78.17	3.00e-107	380.00
IUUC-Aly-005939	Arabidopsis lyrata	46.49	2.00e-57	214.00
IUUC-Ath-006827	Arabidopsis thaliana	47.14	5.00e-58	217.00
IUUC-Ago-007950	Ashbya gossypii	31.76	2.00e-26	112.00
IUUC-Acl-008305	Aspergillus clavatus	36.73	3.00e-39	154.00
IUUC-Afl-008611	Aspergillus flavus	39.57	2.00e-44	172.00
IUUC-Afu-008945	Aspergillus fumigatus	38.82	2.00e-42	165.00
IUUC-Ani-009339	Aspergillus nidulans	37.87	2.00e-42	165.00
IUUC-Ang-009691	Aspergillus niger	36.86	2.00e-41	161.00
IUUC-Aor-009961	Aspergillus oryzae	39.57	2.00e-44	172.00
IUUC-Ate-010316	Aspergillus terreus	38.20	2.00e-43	168.00
IUUC-Ame-011157	Astyanax mexicanus	78.26	1.00e-109	388.00
IUUC-Bgr-012125	Blumeria graminis	36.17	5.00e-37	147.00
IUUC-Bta-012673	Bos taurus	78.07	6.00e-110	389.00
IUUC-Bci-013734	Botrytis cinerea	37.71	5.00e-43	167.00
IUUC-Bdi-014330	Brachypodium distachyon	44.49	4.00e-56	211.00
IUUC-Bol-015214	Brassica oleracea	47.81	9.00e-60	223.00
IUUC-Bra-017491	Brassica rapa	47.81	2.00e-59	221.00
IUUC-Cel-018236	Caenorhabditis elegans	30.67	1.00e-24	105.00
IUUC-Cfa-020371	Canis familiaris	77.89	4.00e-88	316.00
IUUC-Cpo-022036	Cavia porcellus	76.75	1.00e-106	378.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	41.40	4.00e-35	140.00
IUUC-Csa-023854	Chlorocebus sabaeus	78.07	6.00e-109	386.00
IUUC-Cin-025545	Ciona intestinalis	52.65	3.00e-69	254.00
IUUC-Cgl-026409	Colletotrichum gloeosporioides	33.62	1.00e-32	132.00
IUUC-Cne-026914	Cryptococcus neoformans	35.19	3.00e-32	131.00
IUUC-Cme-027216	Cyanidioschyzon merolae	39.22	6.00e-32	130.00
IUUC-Dre-028356	Danio rerio	76.09	3.00e-106	377.00
IUUC-Dse-031461	Dothistroma septosporum	37.97	7.00e-36	143.00
IUUC-Dme-032146	Drosophila melanogaster	48.66	3.00e-61	227.00
IUUC-Eca-033220	Equus caballus	78.07	5.00e-109	386.00
IUUC-Fca-036421	Felis catus	78.51	5.00e-110	389.00
IUUC-Fal-036773	Ficedula albicollis	73.25	2.00e-93	334.00
IUUC-Fox-037830	Fusarium oxysporum	36.80	3.00e-41	161.00
IUUC-Fso-038259	Fusarium solani	35.19	3.00e-36	147.00
IUUC-Gmo-039468	Gadus morhua	74.78	2.00e-91	328.00
IUUC-Ggr-039832	Gaeumannomyces graminis	36.80	2.00e-38	152.00
IUUC-Gga-041205	Gallus gallus	76.75	1.00e-100	358.00
IUUC-Gac-041629	Gasterosteus aculeatus	71.18	2.00e-92	331.00
IUUC-Gma-043057	Glycine max	48.02	2.00e-53	201.00
IUUC-Ggo-044533	Gorilla gorilla	78.17	2.00e-108	384.00
IUUC-Hsa-046754	Homo sapiens	78.51	5.00e-110	389.00
IUUC-Hvu-047176	Hordeum vulgare	39.13	2.00e-43	169.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	75.95	2.00e-71	260.00
IUUC-Kpa-049123	Komagataella pastoris	37.56	2.00e-32	131.00
IUUC-Lpe-051377	Leersia perrieri	44.55	8.00e-47	179.00
IUUC-Loc-051988	Lepisosteus oculatus	83.04	2.00e-115	407.00
IUUC-Lma-053316	Leptosphaeria maculans	38.96	3.00e-44	171.00
IUUC-Laf-053985	Loxodonta africana	78.17	1.00e-108	385.00
IUUC-Mcc-055888	Macaca mulatta	77.19	2.00e-106	377.00
IUUC-Mor-057271	Magnaporthe oryzae	36.36	1.00e-41	163.00
IUUC-Mpo-057343	Magnaporthe poae	29.79	5.00e-20	90.50
IUUC-Mtr-057713	Medicago truncatula	48.46	7.00e-55	206.00
IUUC-Mla-058942	Melampsora laricipopulina	44.78	3.00e-51	194.00
IUUC-Mga-059702	Meleagris gallopavo	76.78	2.00e-92	331.00
IUUC-Mvi-060249	Microbotryum violaceum	41.30	1.00e-40	159.00
IUUC-Mmr-061284	Microcebus murinus	77.22	2.00e-72	265.00
IUUC-Mdo-062639	Monodelphis domestica	66.54	3.00e-103	367.00
IUUC-Mmu-063299	Mus musculus	78.07	3.00e-109	387.00
IUUC-Mac-065075	Musa acuminata	46.32	5.00e-57	213.00
IUUC-Mpu-066769	Mustela putorius furo	78.51	5.00e-110	389.00
IUUC-Mlu-066937	Myotis lucifugus	76.75	2.00e-107	380.00
IUUC-Nfi-068320	Neosartorya fischeri	38.82	2.00e-43	168.00
IUUC-Ncr-068673	Neurospora crassa	37.23	2.00e-43	168.00
IUUC-Nle-069175	Nomascus leucogenys	78.10	3.00e-99	353.00
IUUC-Ont-072170	Oreochromis niloticus	74.67	1.00e-95	342.00
IUUC-Oan-073247	Ornithorhynchus anatinus	77.88	1.00e-49	187.00
IUUC-Ocu-074422	Oryctolagus cuniculus	78.51	7.00e-110	389.00
IUUC-Oba-075098	Oryza barthii	41.15	4.00e-49	187.00
IUUC-Obr-076041	Oryza brachyantha	43.23	1.00e-53	202.00
IUUC-Ogl-076980	Oryza glaberrima	43.67	2.00e-52	198.00
IUUC-Ogu-078978	Oryza glumaepatula	37.55	1.00e-46	179.00
IUUC-Oin-079285	Oryza indica	40.71	2.00e-48	184.00
IUUC-Olo-080671	Oryza longistaminata	41.59	2.00e-49	188.00
IUUC-Ome-081428	Oryza meridionalis	40.71	4.00e-48	184.00
IUUC-Oni-082406	Oryza nivara	41.15	4.00e-49	187.00
IUUC-Opu-083305	Oryza punctata	42.04	8.00e-49	186.00
IUUC-Oru-084969	Oryza rufipogon	41.15	4.00e-49	187.00
IUUC-Osa-085830	Oryza sativa	43.67	2.00e-52	198.00
IUUC-Ola-086893	Oryzias latipes	72.49	1.00e-91	328.00
IUUC-Olu-087858	Ostreococcus lucimarinus	42.04	2.00e-51	195.00
IUUC-Oga-088055	Otolemur garnettii	78.17	2.00e-108	384.00
IUUC-Oar-090319	Ovis aries	77.63	2.00e-109	388.00
IUUC-Pan-092714	Papio anubis	77.73	5.00e-108	382.00
IUUC-Psi-094036	Pelodiscus sinensis	78.50	5.00e-95	340.00
IUUC-Pma-094412	Petromyzon marinus	63.64	2.00e-55	207.00
IUUC-Pno-094997	Phaeosphaeria nodorum	34.77	2.00e-34	139.00
IUUC-Ppa-095519	Physcomitrella patens	52.65	7.00e-68	249.00
IUUC-Pfo-096182	Poecilia formosa	72.29	5.00e-94	336.00
IUUC-Pop-099282	Populus trichocarpa	47.58	8.00e-55	206.00
IUUC-Ppe-101332	Prunus persica	47.58	5.00e-58	217.00
IUUC-Pgr-103430	Puccinia graminis	46.47	2.00e-51	195.00
IUUC-Ptt-103955	Puccinia triticina	48.09	3.00e-52	197.00
IUUC-Pte-104414	Pyrenophora teres	39.32	6.00e-43	167.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	32.08	8.00e-33	133.00
IUUC-Rno-105096	Rattus norvegicus	77.63	3.00e-109	387.00
IUUC-Sce-106412	Saccharomyces cerevisiae	33.68	2.00e-28	119.00
IUUC-Sha-106677	Sarcophilus harrisii	78.04	1.00e-101	361.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	30.09	2.00e-26	112.00
IUUC-Spo-108322	Schizosaccharomyces pombe	32.33	5.00e-27	114.00
IUUC-Ssl-108641	Sclerotinia sclerotiorum	37.50	2.00e-39	155.00
IUUC-Smo-109283	Selaginella moellendorffii	47.86	4.00e-55	207.00
IUUC-Sit-110163	Setaria italica	46.29	6.00e-54	204.00
IUUC-Sly-111613	Solanum lycopersicum	47.58	2.00e-61	228.00
IUUC-Stu-112526	Solanum tuberosum	47.14	1.00e-55	208.00
IUUC-Sbi-114545	Sorghum bicolor	46.29	1.00e-52	199.00
IUUC-Sre-114961	Sporisorium reilianum	39.39	1.00e-38	152.00
IUUC-Ssc-115255	Sus scrofa	77.62	6.00e-100	356.00
IUUC-Tgu-117003	Taeniopygia guttata	76.75	1.00e-99	355.00
IUUC-Tru-118330	Takifugu rubripes	66.12	1.00e-71	264.00
IUUC-Tni-120042	Tetraodon nigroviridis	69.02	1.00e-73	270.00
IUUC-Tca-120976	Theobroma cacao	47.58	2.00e-57	215.00
IUUC-Tre-122149	Trichoderma reesei	37.66	4.00e-41	160.00
IUUC-Tvi-122450	Trichoderma virens	38.10	2.00e-42	165.00
IUUC-Tae-122693	Triticum aestivum	44.35	5.00e-54	204.00
IUUC-Tur-126250	Triticum urartu	42.80	1.00e-52	198.00
IUUC-Tme-126961	Tuber melanosporum	37.50	1.00e-37	149.00
IUUC-Uma-129382	Ustilago maydis	38.79	2.00e-41	162.00
IUUC-Vda-129678	Verticillium dahliae	31.93	1.00e-31	129.00
IUUC-Vpa-130783	Vicugna pacos	75.65	6.00e-50	190.00
IUUC-Vvi-131661	Vitis vinifera	46.49	6.00e-58	216.00
IUUC-Xtr-132428	Xenopus tropicalis	75.22	4.00e-108	383.00
IUUC-Xma-134245	Xiphophorus maculatus	70.31	6.00e-92	329.00
IUUC-Yli-134570	Yarrowia lipolytica	35.42	3.00e-36	144.00
IUUC-Zma-134740	Zea mays	44.54	3.00e-53	201.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence