iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-016686

Ensembl Protein ID

Bra028727.1-P

UniProt Accession

M4EIW2; M4EIW2_BRARP

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra028727	Bra028727.1	Bra028727.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.40e-71	240.8	200	523

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEfl 96
           +GlkN+g+tCYmNS+LQ+L++ip +r+++ +     ++ ++++ p++++  +lq+lf +l ++++++v+++el+k++++    +++++q+D+qE+ 
   Q: 200  VGLKNQGATCYMNSLLQTLYHIPYFRKAVYH-----MPTTENDAPTASIPLALQSLFYKL-QYNDTSVATKELTKSFGWDT--YDSFMQHDVQELN 287
           6******************************.....555555789***************.88999************877..67*********** PP
   S: 97   aflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLe 192
           ++l ++le+++                          k +  + +i++lF+g+  + i c + d +s+r+e+f+dl+l+v+g +     ++  +++
   Q: 288  RVLCEKLEDKM--------------------------KGTVVEGTIQQLFEGHHMNYIECINVDYKSTRKESFYDLQLDVKGCK-----DVYASFD 352
           ***********..........................7899*******************************************.....9****** PP
   S: 193  sftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls....pfctspeekqkekkkYeLiavv 284
           ++++ e+leg+nky+ e   ++q+a+k + +  +P+vL l+LkRf+++  ++s  kin+++efpleLdl+    ++++  + + ++++ Y L++v+
   Q: 353  KYVEVERLEGDNKYHAEGH-GLQDAKKGVLFIDFPPVLQLQLKRFEYDFMRDSMVKINDRYEFPLELDLDredgKYLSP-DADRSVRNLYTLHSVL 446
           ***************9985.79***********************************************9777666666.666678********** PP
   S: 285  vHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg.......................staYvlfYkr 337
           vHsG++++GHY+a+++   +++W++fdD++Vt+ + ++ lee+                        s+aY+l+Y r
   Q: 447  VHSGGVHGGHYYAFIRPtLSDQWYKFDDERVTKEDLKRALEEQYggeeelpqtnpgfnnppfkftkfSNAYMLVYIR 523
           ****************945677*************9999997779******************************87 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MTMVTPPPVD QQEDEEMLVP HSDLVEDPAQ PMEVSETETA VSTVENQPAA EEPPTLKFTW 60
TIPHFSRINT RKQYSDVFVV GGYKWRILIF PKGNNVDHLS MYLDVADAAS LPYGWSRYAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTATGG TGACTCCGCC TCCCGTCGAT GTAATCTCCG ATTCAATCAT TTCTCTCTGT 60
TGATTTGATG CTCTGTGTCC CCCTTGAATC TACTTCGGAT TGTTTGTTTT AGCTGATCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bol-015424	Brassica oleracea	97.72	0.00e+00	2199.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	56.18	4.00e-144	504.00
IUUC-Cme-027103	Cyanidioschyzon merolae	39.28	5.00e-131	462.00
IUUC-Kpa-049121	Komagataella pastoris	32.30	2.00e-138	486.00
IUUC-Osa-085418	Oryza sativa	70.93	0.00e+00	1317.00
IUUC-Sce-106230	Saccharomyces cerevisiae	33.67	1.00e-129	457.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence