iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066559

Ensembl Protein ID

ENSMPUP00000005547.1

UniProt Accession

M3Y2J6; M3Y2J6_MUSPF

Genbank Protein ID

ENSMPUP00000005547

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01078194

Gene Name

PLRG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000005590.1	ENSMPUT00000005642.1	ENSMPUP00000005547.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.20e-44	146.1	203	239
UBD/Beta-Prp	1.10e-63	215.2	298	490

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+c+a  ++   +v+Gs D tik+WDl +g+l
   Q: 203  GHLGWVRCIAVePGnQWFVTGSADRTIKIWDLASGKL 239
           8***********77799***************99987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
           +p  ++l+t srd+t ++wdv+t+  +++lsgh+++v++v+++  ++ ++tgs D ti++wdl +gk+ +tl++h++sv+++ ++p  +
   Q: 298  HPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHY 386
           34444555555555555555555555555555555555555555555555555555555555555555555555555555555555555 PP
   S: 108  klvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelv 196
           +++sGs d+ i+ w+ + g+ ++  lsgh++++n+++v++ + +lvsG++++t+ lWd +tg   ++                      
   Q: 387  TFASGSPDN-IKQWKFPDGSFIQ-NLSGHNAIINTLTVNS-DGVLVSGADNGTMHLWDWRTGYNFQRV--------------------- 451
           555555433.5555555555555.5555555555555555.445555555555555555555555555..................... PP
   S: 197  sgsldgtvklwdlqtgecvrtlnght........dnvksvrfspnderlvsgssDgsiriW 249
                                 ++          + +   +f++ + rl+++ +D++i+++
   Q: 452  ----------------------HAAVqpgsldseSGIFACAFDQSESRLLTAEADKTIKVY 490
           ......................443344444444444444555555555555555555554 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MVEEVQKHSV HTLVFRSLKR THDMFVADNG KPVPLDEESH KRKMAIKLRN EYGPVLHMPT 60
SKENFKEKGP QNASDSYGHK QYPANQGQEV EYLVTGTHPY PPGPGVALTA DTKIQRMPSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGCGCCAG GGCGGTCGAT TCCGGAAGGG ACTGCACAGT TGTGGCAGCG GTTTCTGTGT 60
TGCGAACTAG CGTTTCTTGT CTTTTGGAGC GGCGCGTTGT ACGGCAGCAT CATGGTCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005662--C:DNA replication factor A complex
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0016607--C:nuclear speck
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0034504--P:protein localization to nucleus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	47.01	3.00e-129	455.00
IUUC-Aml-001605	Ailuropoda melanoleuca	99.22	0.00e+00	1063.00
IUUC-Atr-002757	Amborella trichopoda	49.18	2.00e-130	459.00
IUUC-Apl-003198	Anas platyrhynchos	90.89	0.00e+00	983.00
IUUC-Aca-004683	Anolis carolinensis	89.53	0.00e+00	962.00
IUUC-Aly-005775	Arabidopsis lyrata	54.41	7.00e-127	447.00
IUUC-Ath-007460	Arabidopsis thaliana	53.90	5.00e-126	444.00
IUUC-Ago-007884	Ashbya gossypii	49.71	5.00e-107	380.00
IUUC-Acl-008153	Aspergillus clavatus	64.33	2.00e-128	452.00
IUUC-Afl-008384	Aspergillus flavus	57.50	4.00e-131	461.00
IUUC-Afu-009045	Aspergillus fumigatus	64.94	3.00e-129	455.00
IUUC-Ani-009229	Aspergillus nidulans	62.97	2.00e-129	456.00
IUUC-Ang-009812	Aspergillus niger	65.62	1.00e-123	436.00
IUUC-Aor-010059	Aspergillus oryzae	57.50	4.00e-131	461.00
IUUC-Ate-010351	Aspergillus terreus	63.08	1.00e-135	476.00
IUUC-Ame-011613	Astyanax mexicanus	59.38	2.00e-157	548.00
IUUC-Bgr-012042	Blumeria graminis	63.72	4.00e-135	474.00
IUUC-Bta-012406	Bos taurus	97.09	0.00e+00	1040.00
IUUC-Bci-013760	Botrytis cinerea	62.25	5.00e-134	471.00
IUUC-Bdi-014776	Brachypodium distachyon	57.72	6.00e-132	464.00
IUUC-Bol-016189	Brassica oleracea	54.50	1.00e-127	449.00
IUUC-Bra-018044	Brassica rapa	54.50	2.00e-127	449.00
IUUC-Cel-018651	Caenorhabditis elegans	52.33	2.00e-153	535.00
IUUC-Cja-019974	Callithrix jacchus	95.73	0.00e+00	1032.00
IUUC-Cfa-021085	Canis familiaris	99.22	0.00e+00	1067.00
IUUC-Cpo-021458	Cavia porcellus	95.34	0.00e+00	1033.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	59.88	6.00e-124	436.00
IUUC-Csa-023883	Chlorocebus sabaeus	95.92	0.00e+00	1033.00
IUUC-Cho-024623	Choloepus hoffmanni	95.29	0.00e+00	1008.00
IUUC-Cin-025190	Ciona intestinalis	59.46	0.00e+00	645.00
IUUC-Csv-026367	Ciona savignyi	59.96	0.00e+00	653.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	65.95	1.00e-139	489.00
IUUC-Cne-027069	Cryptococcus neoformans	54.61	1.00e-127	449.00
IUUC-Cme-027233	Cyanidioschyzon merolae	29.88	2.00e-34	140.00
IUUC-Dre-028260	Danio rerio	79.07	0.00e+00	850.00
IUUC-Dno-029112	Dasypus novemcinctus	97.48	0.00e+00	1048.00
IUUC-Dor-031118	Dipodomys ordii	94.39	0.00e+00	800.00
IUUC-Dse-031493	Dothistroma septosporum	46.59	3.00e-126	445.00
IUUC-Dme-032138	Drosophila melanogaster	60.08	3.00e-172	597.00
IUUC-Ete-032411	Echinops telfairi	84.57	0.00e+00	838.00
IUUC-Eca-033521	Equus caballus	97.67	0.00e+00	1055.00
IUUC-Eeu-035249	Erinaceus europaeus	82.68	0.00e+00	675.00
IUUC-Fca-036358	Felis catus	98.83	0.00e+00	1064.00
IUUC-Fal-036933	Ficedula albicollis	90.70	0.00e+00	976.00
IUUC-Fox-037713	Fusarium oxysporum	59.68	8.00e-140	490.00
IUUC-Fso-038380	Fusarium solani	63.74	9.00e-139	486.00
IUUC-Gmo-039133	Gadus morhua	78.95	0.00e+00	840.00
IUUC-Ggr-039915	Gaeumannomyces graminis	66.67	1.00e-132	466.00
IUUC-Gga-041176	Gallus gallus	89.73	0.00e+00	974.00
IUUC-Gac-042344	Gasterosteus aculeatus	77.13	0.00e+00	841.00
IUUC-Gma-043328	Glycine max	49.51	1.00e-131	462.00
IUUC-Ggo-044478	Gorilla gorilla	95.73	0.00e+00	1030.00
IUUC-Hsa-046037	Homo sapiens	95.92	0.00e+00	1032.00
IUUC-Hvu-047349	Hordeum vulgare	50.72	3.00e-133	468.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	96.70	0.00e+00	1044.00
IUUC-Kpa-049343	Komagataella pastoris	58.77	5.00e-119	421.00
IUUC-Lch-049830	Latimeria chalumnae	84.11	0.00e+00	908.00
IUUC-Lpe-051442	Leersia perrieri	48.28	4.00e-130	457.00
IUUC-Loc-051794	Lepisosteus oculatus	82.09	0.00e+00	861.00
IUUC-Lma-053137	Leptosphaeria maculans	45.72	1.00e-127	450.00
IUUC-Laf-053471	Loxodonta africana	96.49	0.00e+00	1036.00
IUUC-Mcc-055627	Macaca mulatta	95.73	0.00e+00	1030.00
IUUC-Meu-056148	Macropus eugenii	81.64	0.00e+00	872.00
IUUC-Mor-056960	Magnaporthe oryzae	66.56	1.00e-137	483.00
IUUC-Mtr-057816	Medicago truncatula	47.93	3.00e-127	448.00
IUUC-Mla-059031	Melampsora laricipopulina	65.72	1.00e-127	449.00
IUUC-Mga-059337	Meleagris gallopavo	90.08	0.00e+00	973.00
IUUC-Mvi-060217	Microbotryum violaceum	64.38	6.00e-130	457.00
IUUC-Mmr-061018	Microcebus murinus	97.28	0.00e+00	1049.00
IUUC-Mdo-062863	Monodelphis domestica	91.28	0.00e+00	959.00
IUUC-Mmu-063988	Mus musculus	94.95	0.00e+00	1018.00
IUUC-Mac-064459	Musa acuminata	48.89	8.00e-125	440.00
IUUC-Mlu-067361	Myotis lucifugus	96.88	0.00e+00	1008.00
IUUC-Nfi-068492	Neosartorya fischeri	65.24	2.00e-129	455.00
IUUC-Ncr-068808	Neurospora crassa	60.50	3.00e-137	481.00
IUUC-Nle-069875	Nomascus leucogenys	96.12	0.00e+00	1035.00
IUUC-Opr-070462	Ochotona princeps	97.74	2.00e-157	549.00
IUUC-Ont-071365	Oreochromis niloticus	77.33	0.00e+00	842.00
IUUC-Oan-072708	Ornithorhynchus anatinus	91.44	0.00e+00	990.00
IUUC-Ocu-074594	Oryctolagus cuniculus	96.50	0.00e+00	1041.00
IUUC-Oba-075570	Oryza barthii	59.61	7.00e-128	450.00
IUUC-Obr-076366	Oryza brachyantha	64.83	2.00e-92	331.00
IUUC-Ogl-077153	Oryza glaberrima	59.61	3.00e-127	448.00
IUUC-Ogu-078540	Oryza glumaepatula	59.61	7.00e-128	450.00
IUUC-Oin-079612	Oryza indica	58.79	6.00e-126	444.00
IUUC-Olo-081077	Oryza longistaminata	58.79	6.00e-126	444.00
IUUC-Ome-081236	Oryza meridionalis	58.52	1.00e-125	443.00
IUUC-Oni-082499	Oryza nivara	59.61	7.00e-128	450.00
IUUC-Opu-083499	Oryza punctata	58.79	1.00e-125	443.00
IUUC-Oru-084276	Oryza rufipogon	59.61	7.00e-128	450.00
IUUC-Osa-085849	Oryza sativa	59.61	7.00e-128	450.00
IUUC-Ola-086655	Oryzias latipes	75.63	0.00e+00	820.00
IUUC-Olu-087637	Ostreococcus lucimarinus	59.28	2.00e-120	425.00
IUUC-Oga-087934	Otolemur garnettii	96.51	0.00e+00	1039.00
IUUC-Oar-090185	Ovis aries	96.12	0.00e+00	1029.00
IUUC-Ptr-091198	Pan troglodytes	96.12	0.00e+00	1035.00
IUUC-Pan-092622	Papio anubis	95.92	0.00e+00	1033.00
IUUC-Psi-093320	Pelodiscus sinensis	90.14	0.00e+00	976.00
IUUC-Pma-094638	Petromyzon marinus	77.09	0.00e+00	844.00
IUUC-Pno-094826	Phaeosphaeria nodorum	48.78	8.00e-105	374.00
IUUC-Ppa-095576	Physcomitrella patens	64.31	2.00e-124	439.00
IUUC-Pfo-096894	Poecilia formosa	77.99	0.00e+00	845.00
IUUC-Pab-098020	Pongo abelii	96.31	0.00e+00	1035.00
IUUC-Pop-099180	Populus trichocarpa	48.92	6.00e-127	447.00
IUUC-Pca-100909	Procavia capensis	91.40	0.00e+00	830.00
IUUC-Ppe-101346	Prunus persica	46.75	6.00e-126	444.00
IUUC-Pva-102167	Pteropus vampyrus	79.61	0.00e+00	810.00
IUUC-Pgr-103516	Puccinia graminis	50.31	1.00e-129	456.00
IUUC-Ptt-103738	Puccinia triticina	49.90	3.00e-130	458.00
IUUC-Pte-104352	Pyrenophora teres	53.16	4.00e-131	461.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	53.64	5.00e-132	464.00
IUUC-Rno-105291	Rattus norvegicus	95.53	0.00e+00	1027.00
IUUC-Sce-106204	Saccharomyces cerevisiae	50.45	5.00e-104	371.00
IUUC-Sha-106943	Sarcophilus harrisii	90.33	0.00e+00	949.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	65.40	6.00e-130	457.00
IUUC-Spo-108049	Schizosaccharomyces pombe	62.61	2.00e-135	475.00
IUUC-Smo-109043	Selaginella moellendorffii	60.18	6.00e-125	440.00
IUUC-Sit-110431	Setaria italica	58.38	8.00e-133	467.00
IUUC-Sly-111391	Solanum lycopersicum	62.30	2.00e-119	422.00
IUUC-Stu-112364	Solanum tuberosum	55.59	2.00e-96	345.00
IUUC-Sar-113450	Sorex araneus	98.28	0.00e+00	721.00
IUUC-Sbi-113829	Sorghum bicolor	50.00	4.00e-131	461.00
IUUC-Sre-115153	Sporisorium reilianum	62.11	6.00e-122	431.00
IUUC-Ssc-115798	Sus scrofa	96.90	0.00e+00	1041.00
IUUC-Tgu-117417	Taeniopygia guttata	91.23	0.00e+00	979.00
IUUC-Tru-117615	Takifugu rubripes	75.24	0.00e+00	782.00
IUUC-Tsy-119480	Tarsius syrichta	96.68	0.00e+00	1031.00
IUUC-Tni-119847	Tetraodon nigroviridis	75.19	0.00e+00	813.00
IUUC-Tca-121287	Theobroma cacao	46.76	5.00e-128	451.00
IUUC-Tre-122010	Trichoderma reesei	65.20	6.00e-143	500.00
IUUC-Tvi-122475	Trichoderma virens	64.04	1.00e-141	496.00
IUUC-Tae-124397	Triticum aestivum	50.31	9.00e-135	473.00
IUUC-Tur-126116	Triticum urartu	50.89	8.00e-102	363.00
IUUC-Tme-126992	Tuber melanosporum	65.55	1.00e-136	479.00
IUUC-Tbe-127803	Tupaia belangeri	85.28	0.00e+00	742.00
IUUC-Ttr-128933	Tursiops truncatus	97.67	0.00e+00	1048.00
IUUC-Uma-129447	Ustilago maydis	60.00	6.00e-118	417.00
IUUC-Vda-129780	Verticillium dahliae	63.53	7.00e-138	483.00
IUUC-Vpa-130557	Vicugna pacos	93.04	4.00e-125	441.00
IUUC-Vvi-130918	Vitis vinifera	47.67	1.00e-122	432.00
IUUC-Xtr-132409	Xenopus tropicalis	85.49	0.00e+00	889.00
IUUC-Xma-133420	Xiphophorus maculatus	78.10	0.00e+00	850.00
IUUC-Yli-134362	Yarrowia lipolytica	58.84	1.00e-120	426.00
IUUC-Zma-135804	Zea mays	57.14	4.00e-126	444.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence