iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cgl-026463

Ensembl Protein ID

ELA26765

UniProt Accession

L2FKQ1; L2FKQ1_COLGN

Genbank Protein ID

ELA26765.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

KB021028

Gene Name

CGGC5_12243

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CGGC5_12243	ELA26765	ELA26765

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-52	178.0	46	619

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp....................kepkgellkslqklfeelw..kskkkavsprellkalkk 79
           +Gl+N  N C++NS+LQ+L+ + elr +l ++++++  ++ +                      + g ++k l++++ +l      kk++s  +++++l++
   Q: 46   VGLRNAANDCFINSTLQALAGLGELRIYLIRETHRRNIDD-DgvysqlvqppgktypdwkieGMQRGLVTKGLKDMLDSLNerPIYKKSISAIDFVRVLEQ 145
           6******************************433333333.34688888888888888888777777999**********977778999************ PP
   S: 80   eaeefsgyeqqDaqEflaflldqleeelkk........eknkpkeeeeeedkselsde.........................................ae 131
           + ++  + +qqDaqEfl+++ ++l+ee +         +       ++                                                   + 
   Q: 146  AFRQRISRQQQDAQEFLQIVAERLKEEYHAgerarahaQ-----LAASR--------AasagasvngeavqeklenlnltnghadgsssdlptptvpkiQT 233
           ****99**********************55433222220.....22222........12234456688888889999999999999999999999887766 PP
   S: 132  ekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck................... 212
           +  + + ++     ++g+++sq  c++c+ ++  ree+f+ l+l+vp+ ++t   +l++c+++++k+e++++   ++ce+c+                   
   Q: 234  NGVHISADEDEGFPMEGRYESQSECQTCGYKTkPREETFYMLTLNVPQTSST---TLSSCFDEIFKTEMIDD---FKCERCRlihgeeslkkdlakaqtds 328
           666666667777899****************999****************99...***************97...************************** PP
   S: 213  ...................................kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkY 278
                                               k++  ++++l+ +P++L +hL+R  +++    ++k++ kv fp++L l     +        ++Y
   Q: 329  ekqaleeairklrfaidvdpehvpedillpdistaPKRKIARSTRLTCFPRILAVHLSRSIYEQ---TSTKNSAKVAFPERLPLGGLRDR--------RNY 418
           *********999999999999999999999999998888*********************8866...4789*************965555........89* PP
   S: 279  eLiavvvHsGslssGHYvayvkn.............................................................................. 301
           +L++ v H+Gs++sGHY ++ ++                                                                              
   Q: 419  KLLGLVTHKGSHHSGHYESFRRQntyapysnqntfqpsgiysktaspaatpqpstpqlgaspavstpdlltpssetnstppslsssdgsprermkkrispt 519
           ***************************************************************************************************** PP
   S: 302  ..................................................................ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
                                                                              +++W++++D+kV+e k +evl   +++ Y+lfY+
   Q: 520  saprdkqrepdsgsirsvksitasakstvskisqrvsgnstpstspprsapmavaprppvhrrkkqPTDRWWRISDEKVREAKTSEVLD-LRREVYLLFYE 619
           *******************************************999999999999999999854444444*******************.56********8 PP

Organism

Colletotrichum gloeosporioides

Protein Sequence
(Fasta)

MPDKNLTTIS YAAGASLAAI ALVYVFAPTF TIDETSTSSS RRKGVVGLRN AANDCFINST 60
LQALAGLGEL RIYLIRETHR RNIDDDGVYS QLVQPPGKTY PDWKIEGMQR GLVTKGLKDM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCGACA AAAACCTCAC CACGATTTCC TACGCCGCTG GCGCATCTCT CGCCGCAATC 60
GCCCTCGTCT ACGTGTTTGC GCCCACTTTC ACAATCGACG AGACCAGTAC ATCGTCTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007955	Ashbya gossypii	28.36	6.00e-26	110.00
IUUC-Acl-008228	Aspergillus clavatus	51.53	1.00e-124	438.00
IUUC-Afl-008530	Aspergillus flavus	50.98	7.00e-125	439.00
IUUC-Afu-008943	Aspergillus fumigatus	45.05	3.00e-138	483.00
IUUC-Ang-009829	Aspergillus niger	44.08	4.00e-126	443.00
IUUC-Aor-009934	Aspergillus oryzae	46.52	7.00e-131	459.00
IUUC-Ate-010439	Aspergillus terreus	52.44	7.00e-129	452.00
IUUC-Bgr-012072	Blumeria graminis	45.68	9.00e-122	428.00
IUUC-Bci-013641	Botrytis cinerea	48.73	4.00e-149	520.00
IUUC-Dse-031517	Dothistroma septosporum	43.21	7.00e-124	436.00
IUUC-Fox-037837	Fusarium oxysporum	57.34	0.00e+00	656.00
IUUC-Fso-038234	Fusarium solani	56.67	0.00e+00	644.00
IUUC-Ggr-039945	Gaeumannomyces graminis	62.32	2.00e-72	265.00
IUUC-Kpa-049259	Komagataella pastoris	26.10	7.00e-19	87.40
IUUC-Lch-050662	Latimeria chalumnae	23.17	3.00e-13	67.80
IUUC-Lma-053197	Leptosphaeria maculans	45.01	1.00e-109	388.00
IUUC-Mor-057061	Magnaporthe oryzae	53.40	6.00e-138	482.00
IUUC-Mpo-057549	Magnaporthe poae	62.32	3.00e-73	268.00
IUUC-Nfi-068557	Neosartorya fischeri	50.54	6.00e-124	436.00
IUUC-Ncr-068961	Neurospora crassa	46.89	2.00e-130	457.00
IUUC-Pno-094802	Phaeosphaeria nodorum	53.39	7.00e-128	448.00
IUUC-Ptt-103779	Puccinia triticina	30.00	3.00e-19	89.00
IUUC-Pte-104416	Pyrenophora teres	46.85	2.00e-136	477.00
IUUC-Pyt-104503	Pyrenophora triticirepentis	47.71	2.00e-144	504.00
IUUC-Sce-106365	Saccharomyces cerevisiae	27.27	5.00e-21	94.00
IUUC-Tre-121937	Trichoderma reesei	54.91	3.00e-172	596.00
IUUC-Tvi-122428	Trichoderma virens	55.93	5.00e-171	592.00
IUUC-Tme-126993	Tuber melanosporum	47.11	3.00e-95	340.00
IUUC-Vda-129757	Verticillium dahliae	62.12	0.00e+00	713.00
IUUC-Yli-134426	Yarrowia lipolytica	31.36	2.00e-37	149.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence