iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037064

Ensembl Protein ID

ENSFALP00000012133.1

UniProt Accession

U3KAS9; U3KAS9_FICAL

Genbank Protein ID

ENSFALP00000012133

Protein Name

Autophagy protein 5

Genbank Nucleotide ID

AGTO01001221

Gene Name

ATG5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000011631.1	ENSFALT00000012183.1	ENSFALP00000012133.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/Other	21.69	5.00e-10	59.70	IUUC-Sce-106216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ficedula albicollis

Functional Description
(View)

Involved in autophagic vesicle formation.

Protein Sequence
(Fasta)

MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RISYLTLVTD KVKKHFQKVM 60
RQEEVSEIWF EYEGTPLKWH YPIGLLFDLH ASNTALPWSI TVHFKNFPEK DLLHCHSKDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG 60
GGGGGGGGGG GGCCTCGGTG ACCCCCGGGC GGTGGCCGCC CCGCCGGGGG CCCGGCTCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-1185--Reference proteome
KW-0832--Ubl conjugation

Interpro

IPR007239--Atg5

Pfam

PF04106--APG5

Gene Ontology

GO:0005776--C:autophagosome
GO:0005930--C:axoneme
GO:0044233--C:ER-mitochondrion membrane contact site
GO:0034045--C:pre-autophagosomal structure membrane
GO:0035973--P:aggrephagy
GO:0019883--P:antigen processing and presentation of endogenous antigen
GO:0001974--P:blood vessel remodeling
GO:0019725--P:cellular homeostasis
GO:0071500--P:cellular response to nitrosative stress
GO:0009267--P:cellular response to starvation
GO:0060047--P:heart contraction
GO:0000422--P:mitophagy
GO:0043066--P:negative regulation of apoptotic process
GO:2000619--P:negative regulation of histone H4-K16 acetylation
GO:0050765--P:negative regulation of phagocytosis
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000378--P:negative regulation of reactive oxygen species metabolic process
GO:0039689--P:negative stranded viral RNA replication
GO:0045060--P:negative thymic T cell selection
GO:0048840--P:otolith development
GO:0070257--P:positive regulation of mucus secretion
GO:0061739--P:protein lipidation involved in autophagosome assembly
GO:1902017--P:regulation of cilium assembly
GO:0002739--P:regulation of cytokine secretion involved in immune response
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0042493--P:response to drug
GO:0009620--P:response to fungus
GO:0042311--P:vasodilation
GO:0055015--P:ventricular cardiac muscle cell development

KEGG

fab:101820801

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000583	Aegilops tauschii	32.35	1.00e-23	105.00
IUUC-Aml-002403	Ailuropoda melanoleuca	89.17	2.00e-148	517.00
IUUC-Atr-002645	Amborella trichopoda	25.82	8.00e-22	97.40
IUUC-Apl-003611	Anas platyrhynchos	97.82	2.00e-163	567.00
IUUC-Aca-004411	Anolis carolinensis	90.29	8.00e-151	525.00
IUUC-Aly-005636	Arabidopsis lyrata	26.36	2.00e-25	109.00
IUUC-Ath-006959	Arabidopsis thaliana	26.67	1.00e-25	110.00
IUUC-Ago-007978	Ashbya gossypii	24.80	9.00e-07	47.00
IUUC-Acl-008328	Aspergillus clavatus	25.40	3.00e-21	95.10
IUUC-Afl-008638	Aspergillus flavus	26.71	3.00e-26	112.00
IUUC-Afu-009042	Aspergillus fumigatus	27.48	6.00e-29	120.00
IUUC-Ani-009364	Aspergillus nidulans	30.05	1.00e-24	106.00
IUUC-Aor-009889	Aspergillus oryzae	26.71	2.00e-26	112.00
IUUC-Ate-010511	Aspergillus terreus	34.41	8.00e-11	58.50
IUUC-Ame-011644	Astyanax mexicanus	84.81	2.00e-37	145.00
IUUC-Bgr-012153	Blumeria graminis	28.15	5.00e-18	84.30
IUUC-Bta-012360	Bos taurus	93.08	2.00e-84	303.00
IUUC-Bci-013723	Botrytis cinerea	25.61	2.00e-15	75.50
IUUC-Bdi-014520	Brachypodium distachyon	28.57	3.00e-18	85.90
IUUC-Bol-016053	Brassica oleracea	26.27	1.00e-28	120.00
IUUC-Bra-017072	Brassica rapa	26.95	3.00e-29	122.00
IUUC-Cel-018529	Caenorhabditis elegans	34.91	2.00e-37	149.00
IUUC-Cja-019569	Callithrix jacchus	90.18	5.00e-150	523.00
IUUC-Cfa-020473	Canis familiaris	90.55	2.00e-150	524.00
IUUC-Cpo-021421	Cavia porcellus	88.73	7.00e-148	515.00
IUUC-Cre-022862	Chlamydomonas reinhardtii	30.52	4.00e-17	81.30
IUUC-Csa-024197	Chlorocebus sabaeus	90.18	5.00e-150	523.00
IUUC-Cho-024521	Choloepus hoffmanni	87.03	2.00e-123	434.00
IUUC-Cin-025119	Ciona intestinalis	44.78	5.00e-66	243.00
IUUC-Csv-026192	Ciona savignyi	45.52	1.00e-66	245.00
IUUC-Cgl-026686	Colletotrichum gloeosporioides	23.36	3.00e-10	58.50
IUUC-Dre-028466	Danio rerio	80.36	5.00e-135	473.00
IUUC-Dse-031228	Dothistroma septosporum	27.12	5.00e-31	127.00
IUUC-Dme-031703	Drosophila melanogaster	47.97	1.00e-73	269.00
IUUC-Ete-032482	Echinops telfairi	86.61	5.00e-124	436.00
IUUC-Eca-034036	Equus caballus	89.45	1.00e-149	521.00
IUUC-Eeu-035235	Erinaceus europaeus	91.19	3.00e-83	301.00
IUUC-Fca-036263	Felis catus	90.55	8.00e-151	525.00
IUUC-Fox-037813	Fusarium oxysporum	25.44	1.00e-16	79.70
IUUC-Fso-038139	Fusarium solani	25.61	1.00e-17	82.80
IUUC-Gmo-039509	Gadus morhua	82.43	9.00e-113	399.00
IUUC-Ggr-040111	Gaeumannomyces graminis	24.61	1.00e-13	70.10
IUUC-Gga-040517	Gallus gallus	97.82	9.00e-163	565.00
IUUC-Gac-042270	Gasterosteus aculeatus	70.80	2.00e-116	411.00
IUUC-Gma-044400	Glycine max	35.84	5.00e-23	100.00
IUUC-Ggo-045048	Gorilla gorilla	89.82	2.00e-148	517.00
IUUC-Hsa-046744	Homo sapiens	90.55	6.00e-150	522.00
IUUC-Kpa-049174	Komagataella pastoris	22.67	8.00e-13	67.40
IUUC-Lch-049475	Latimeria chalumnae	87.64	5.00e-148	516.00
IUUC-Lpe-051283	Leersia perrieri	32.62	2.00e-21	97.80
IUUC-Loc-052446	Lepisosteus oculatus	82.55	8.00e-142	495.00
IUUC-Lma-053278	Leptosphaeria maculans	26.88	2.00e-30	125.00
IUUC-Laf-054020	Loxodonta africana	89.17	2.00e-148	517.00
IUUC-Mcc-055176	Macaca mulatta	90.55	6.00e-150	522.00
IUUC-Mor-057164	Magnaporthe oryzae	25.00	8.00e-17	80.50
IUUC-Mpo-057428	Magnaporthe poae	26.73	3.00e-14	72.00
IUUC-Mtr-058424	Medicago truncatula	35.09	1.00e-22	99.80
IUUC-Mla-058872	Melampsora laricipopulina	29.08	4.00e-30	125.00
IUUC-Mga-059859	Meleagris gallopavo	97.82	9.00e-163	565.00
IUUC-Mmr-061482	Microcebus murinus	90.91	1.00e-150	524.00
IUUC-Mdo-062371	Monodelphis domestica	92.00	2.00e-155	540.00
IUUC-Mmu-063139	Mus musculus	88.73	8.00e-149	518.00
IUUC-Mac-065332	Musa acuminata	24.21	4.00e-25	108.00
IUUC-Mpu-066783	Mustela putorius furo	89.82	2.00e-149	520.00
IUUC-Mlu-068165	Myotis lucifugus	88.81	1.00e-146	511.00
IUUC-Nfi-068578	Neosartorya fischeri	26.84	6.00e-29	120.00
IUUC-Ncr-068636	Neurospora crassa	24.23	3.00e-12	65.50
IUUC-Nle-069740	Nomascus leucogenys	90.18	8.00e-150	522.00
IUUC-Opr-070802	Ochotona princeps	91.82	2.00e-82	298.00
IUUC-Ont-072222	Oreochromis niloticus	80.07	1.00e-135	475.00
IUUC-Oan-072760	Ornithorhynchus anatinus	91.37	4.00e-109	386.00
IUUC-Ocu-074844	Oryctolagus cuniculus	87.21	8.00e-91	325.00
IUUC-Oba-075834	Oryza barthii	31.07	1.00e-22	100.00
IUUC-Obr-076230	Oryza brachyantha	28.85	2.00e-12	66.20
IUUC-Ogl-077554	Oryza glaberrima	31.07	1.00e-22	100.00
IUUC-Ogu-078687	Oryza glumaepatula	31.07	8.00e-23	100.00
IUUC-Oin-079677	Oryza indica	24.63	9.00e-24	103.00
IUUC-Olo-081078	Oryza longistaminata	33.33	6.00e-23	102.00
IUUC-Ome-081548	Oryza meridionalis	32.18	6.00e-25	109.00
IUUC-Oni-082050	Oryza nivara	31.64	3.00e-23	102.00
IUUC-Opu-083609	Oryza punctata	31.46	2.00e-23	102.00
IUUC-Oru-085057	Oryza rufipogon	31.64	5.00e-23	101.00
IUUC-Osa-085917	Oryza sativa	31.64	6.00e-23	101.00
IUUC-Ola-087032	Oryzias latipes	77.82	2.00e-133	467.00
IUUC-Oga-088468	Otolemur garnettii	89.53	1.00e-151	528.00
IUUC-Oar-089751	Ovis aries	90.18	3.00e-150	523.00
IUUC-Ptr-091064	Pan troglodytes	90.55	6.00e-150	522.00
IUUC-Pan-092505	Papio anubis	89.53	3.00e-148	517.00
IUUC-Psi-093086	Pelodiscus sinensis	91.67	5.00e-155	539.00
IUUC-Pno-094825	Phaeosphaeria nodorum	27.05	1.00e-26	112.00
IUUC-Ppa-095419	Physcomitrella patens	31.93	6.00e-24	104.00
IUUC-Pfo-096224	Poecilia formosa	78.26	1.00e-132	464.00
IUUC-Pab-098501	Pongo abelii	89.82	1.00e-148	518.00
IUUC-Pop-099243	Populus trichocarpa	26.75	2.00e-24	106.00
IUUC-Ppe-101255	Prunus persica	26.36	2.00e-27	115.00
IUUC-Pva-102828	Pteropus vampyrus	89.45	6.00e-149	519.00
IUUC-Pgr-103672	Puccinia graminis	28.62	5.00e-26	111.00
IUUC-Ptt-104013	Puccinia triticina	26.75	1.00e-22	100.00
IUUC-Pyt-104615	Pyrenophora triticirepentis	28.01	1.00e-29	123.00
IUUC-Rno-106089	Rattus norvegicus	84.90	2.00e-126	444.00
IUUC-Sce-106216	Saccharomyces cerevisiae	21.69	1.00e-10	59.70
IUUC-Sha-106484	Sarcophilus harrisii	90.91	5.00e-154	536.00
IUUC-Sja-107699	Schizosaccharomyces japonicus	28.62	7.00e-28	117.00
IUUC-Spo-108177	Schizosaccharomyces pombe	27.71	2.00e-22	99.40
IUUC-Ssl-108475	Sclerotinia sclerotiorum	26.30	3.00e-16	78.60
IUUC-Smo-109473	Selaginella moellendorffii	25.99	3.00e-21	95.10
IUUC-Sit-110736	Setaria italica	33.16	2.00e-27	116.00
IUUC-Sly-111657	Solanum lycopersicum	35.98	8.00e-26	110.00
IUUC-Sar-113050	Sorex araneus	74.48	1.00e-100	358.00
IUUC-Sbi-114258	Sorghum bicolor	31.50	3.00e-25	108.00
IUUC-Sre-114902	Sporisorium reilianum	31.19	3.00e-24	105.00
IUUC-Ssc-116166	Sus scrofa	85.09	2.00e-141	494.00
IUUC-Tgu-116814	Taeniopygia guttata	99.27	1.00e-164	571.00
IUUC-Tru-118172	Takifugu rubripes	78.99	2.00e-133	467.00
IUUC-Tsy-119010	Tarsius syrichta	78.18	4.00e-127	446.00
IUUC-Tni-120397	Tetraodon nigroviridis	82.41	2.00e-101	360.00
IUUC-Tca-121283	Theobroma cacao	26.67	1.00e-26	114.00
IUUC-Tvi-122545	Trichoderma virens	23.02	2.00e-14	72.40
IUUC-Tae-122685	Triticum aestivum	31.58	2.00e-23	102.00
IUUC-Tur-126407	Triticum urartu	32.89	4.00e-23	101.00
IUUC-Tme-126913	Tuber melanosporum	31.93	5.00e-41	160.00
IUUC-Tbe-127738	Tupaia belangeri	80.61	6.00e-96	342.00
IUUC-Ttr-128528	Tursiops truncatus	90.18	7.00e-150	522.00
IUUC-Uma-129625	Ustilago maydis	28.57	1.00e-22	100.00
IUUC-Vda-129906	Verticillium dahliae	22.31	1.00e-10	60.10
IUUC-Vpa-130223	Vicugna pacos	89.09	3.00e-144	503.00
IUUC-Vvi-131617	Vitis vinifera	34.76	7.00e-24	104.00
IUUC-Xtr-132288	Xenopus tropicalis	86.91	5.00e-147	513.00
IUUC-Xma-134214	Xiphophorus maculatus	83.42	3.00e-99	353.00
IUUC-Yli-134377	Yarrowia lipolytica	22.89	3.00e-10	58.50
IUUC-Zma-135108	Zea mays	34.03	1.00e-22	100.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence