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Tag Content
UUCD2 ID IUUC-Xtr-132083
UUCD1 version UUC-XeT-00916
Ensembl Protein ID ENSXETP00000047773.3
UniProt Accession Q5BJ90; WDR12_XENTR
Genbank Protein ID AAH91577.1
Protein Name Ribosome biogenesis protein wdr12; WD repeat-containing protein 12
Genbank Nucleotide ID BC091577
Gene Name wdr12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000022077.3 ENSXETT00000047773.3 ENSXETP00000047773.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.80e-43 144.7 341 376
UBD/Beta-Prp 6.40e-48 163.6 249 412
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgv 34
           Ht++vt++++  s    lvsGs D+ +k+WD+r+++
   Q: 341  HTGWVTSVKWspSHeQQLVSGSLDKLVKLWDTRSCK 376
           ***********754799**************99876 PP
   

   UBD/Beta-Prp
   S: 86   cvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk...l 171
           +++tl+gh++ v s+ +s   d + s+s+d  i++wd+etg++ + tl+g++ v nc++++p ++ l+sGs+Dr +rlWd ++++   +
   Q: 249  PIVTLSGHSEAVSSVLWSD-VDEICSASWDHNIKIWDVETGTVKS-TLAGNK-VFNCISYSPLSQRLASGSTDRHIRLWDPRSKDgslV 334
           689***************9.9***********************9.***987.99**************************66652223 PP
   S: 172  lrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           l  lt+ ht+ v+s++++++  ++lvsgsld+ vklwd +  +  ++ l +h+d v+sv+ + +  +++sg+sD+ ++ +
   Q: 335  LCSLTS-HTGWVTSVKWSPSHeQQLVSGSLDKLVKLWDTRsCKAPLYDLAAHSDKVLSVDWT-DAGLILSGGSDNKLYSY 412
           455587.***********9888******************54566****************9.9**********998776 PP
   
Organism Xenopus tropicalis
Functional Description
(View)

Functional Description


     Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
 Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Protein Sequence
(Fasta)
MAQIQARFFT EEEKYKVDDV PFSIPATSEI VDLSNLINKL LETKNGDHKP VEFDFLVKSQ 60
FLRMPLIKHM EAEGISTEVV VEIEYVEKIT APQPEECMMH DDWVSSIAGT EEWILTGSYD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Xtr-132083|E3,WD_repeat;UBD,Beta-Prp|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGATGTGCTC GGAGTGCAGG ACTGCTCCGT GTAGACACGT GGTTGGCTTC TCGCTTGTTG 60
CGTAGCGGTG TAGCTGGAGT GTGCGTCCCT AGAATTAGAG TTCCCGGCTC CGGCTGGTTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132083|E3,WD_repeat;UBD,Beta-Prp|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0008283--P:cell proliferation
GO:0000460--P:maturation of 5.8S rRNA
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470--P:maturation of LSU-rRNA
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KEGG xtr:595016
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000532 Aegilops tauschii 34.05 4.00e-60 225.00
IUUC-Aml-001997 Ailuropoda melanoleuca 81.22 0.00e+00 628.00
IUUC-Atr-002544 Amborella trichopoda 34.29 2.00e-55 209.00
IUUC-Apl-003981 Anas platyrhynchos 79.68 2.00e-169 588.00
IUUC-Aca-004370 Anolis carolinensis 80.71 0.00e+00 669.00
IUUC-Aly-006455 Arabidopsis lyrata 34.38 6.00e-60 224.00
IUUC-Ath-006669 Arabidopsis thaliana 34.62 1.00e-54 206.00
IUUC-Ago-007864 Ashbya gossypii 30.54 1.00e-39 157.00
IUUC-Acl-008177 Aspergillus clavatus 29.13 3.00e-38 152.00
IUUC-Afl-008617 Aspergillus flavus 29.20 5.00e-37 148.00
IUUC-Afu-008752 Aspergillus fumigatus 27.67 6.00e-36 145.00
IUUC-Ani-009136 Aspergillus nidulans 30.85 3.00e-38 152.00
IUUC-Ang-009701 Aspergillus niger 29.41 9.00e-35 141.00
IUUC-Aor-009884 Aspergillus oryzae 29.44 4.00e-37 149.00
IUUC-Ame-011432 Astyanax mexicanus 74.00 0.00e+00 630.00
IUUC-Bgr-012218 Blumeria graminis 28.78 7.00e-35 141.00
IUUC-Bta-012829 Bos taurus 81.80 0.00e+00 656.00
IUUC-Bci-013953 Botrytis cinerea 29.64 2.00e-37 149.00
IUUC-Bdi-014351 Brachypodium distachyon 36.02 7.00e-56 211.00
IUUC-Bol-016190 Brassica oleracea 34.37 2.00e-52 199.00
IUUC-Bra-018095 Brassica rapa 33.33 3.00e-52 198.00
IUUC-Cel-018569 Caenorhabditis elegans 34.06 7.00e-49 187.00
IUUC-Cja-019468 Callithrix jacchus 81.09 0.00e+00 638.00
IUUC-Cfa-020471 Canis familiaris 80.14 0.00e+00 643.00
IUUC-Cpo-022260 Cavia porcellus 81.09 0.00e+00 640.00
IUUC-Cre-022614 Chlamydomonas reinhardtii 31.06 9.00e-40 157.00
IUUC-Csa-023989 Chlorocebus sabaeus 81.32 0.00e+00 640.00
IUUC-Cho-024426 Choloepus hoffmanni 79.68 7.00e-135 473.00
IUUC-Cin-025789 Ciona intestinalis 43.41 1.00e-95 343.00
IUUC-Cne-027063 Cryptococcus neoformans 24.95 4.00e-20 92.40
IUUC-Dre-027907 Danio rerio 75.65 0.00e+00 645.00
IUUC-Dno-029225 Dasypus novemcinctus 79.43 0.00e+00 644.00
IUUC-Dor-031082 Dipodomys ordii 67.38 2.00e-140 491.00
IUUC-Dse-031308 Dothistroma septosporum 28.34 6.00e-38 151.00
IUUC-Dme-032189 Drosophila melanogaster 40.81 2.00e-91 329.00
IUUC-Ete-032247 Echinops telfairi 75.65 2.00e-172 598.00
IUUC-Eca-034285 Equus caballus 80.38 0.00e+00 649.00
IUUC-Eeu-035322 Erinaceus europaeus 72.61 5.00e-157 546.00
IUUC-Fca-036114 Felis catus 80.38 0.00e+00 647.00
IUUC-Fal-036891 Ficedula albicollis 80.23 6.00e-158 549.00
IUUC-Fox-037965 Fusarium oxysporum 25.69 2.00e-33 136.00
IUUC-Fso-038244 Fusarium solani 25.68 7.00e-32 131.00
IUUC-Gmo-039040 Gadus morhua 73.52 0.00e+00 635.00
IUUC-Ggr-040093 Gaeumannomyces graminis 22.86 3.00e-15 76.60
IUUC-Gga-040610 Gallus gallus 78.01 0.00e+00 653.00
IUUC-Gac-042117 Gasterosteus aculeatus 73.05 1.00e-178 618.00
IUUC-Gma-043146 Glycine max 37.26 5.00e-66 244.00
IUUC-Ggo-045179 Gorilla gorilla 81.32 0.00e+00 632.00
IUUC-Hsa-046114 Homo sapiens 81.56 0.00e+00 635.00
IUUC-Hvu-047331 Hordeum vulgare 35.22 7.00e-55 207.00
IUUC-Itr-048275 Ictidomys tridecemlineatus 81.09 0.00e+00 650.00
IUUC-Kpa-049304 Komagataella pastoris 30.53 7.00e-45 174.00
IUUC-Lch-050655 Latimeria chalumnae 73.08 1.00e-135 475.00
IUUC-Lpe-051675 Leersia perrieri 34.93 6.00e-59 221.00
IUUC-Loc-052868 Lepisosteus oculatus 77.78 0.00e+00 639.00
IUUC-Lma-053258 Leptosphaeria maculans 26.39 1.00e-34 142.00
IUUC-Laf-053993 Loxodonta africana 80.38 0.00e+00 649.00
IUUC-Mcc-055128 Macaca mulatta 66.19 4.00e-141 493.00
IUUC-Meu-056501 Macropus eugenii 70.51 2.00e-142 498.00
IUUC-Mor-057114 Magnaporthe oryzae 26.30 3.00e-29 122.00
IUUC-Mtr-058367 Medicago truncatula 36.93 1.00e-59 223.00
IUUC-Mla-059107 Melampsora laricipopulina 28.05 4.00e-31 129.00
IUUC-Mga-059745 Meleagris gallopavo 76.24 0.00e+00 629.00
IUUC-Mvi-060362 Microbotryum violaceum 28.79 9.00e-32 131.00
IUUC-Mdo-062257 Monodelphis domestica 77.67 0.00e+00 653.00
IUUC-Mmu-063546 Mus musculus 79.20 0.00e+00 644.00
IUUC-Mac-065540 Musa acuminata 34.45 2.00e-56 213.00
IUUC-Mpu-066284 Mustela putorius furo 80.85 0.00e+00 650.00
IUUC-Mlu-067241 Myotis lucifugus 79.91 0.00e+00 645.00
IUUC-Nfi-068260 Neosartorya fischeri 28.78 3.00e-37 149.00
IUUC-Ncr-068719 Neurospora crassa 27.43 1.00e-29 124.00
IUUC-Nle-068981 Nomascus leucogenys 81.32 0.00e+00 636.00
IUUC-Opr-071218 Ochotona princeps 74.87 1.00e-167 582.00
IUUC-Ont-071646 Oreochromis niloticus 74.58 0.00e+00 631.00
IUUC-Oan-073453 Ornithorhynchus anatinus 80.85 0.00e+00 682.00
IUUC-Ocu-074008 Oryctolagus cuniculus 80.61 0.00e+00 651.00
IUUC-Oba-075712 Oryza barthii 30.84 4.00e-43 168.00
IUUC-Obr-076721 Oryza brachyantha 35.08 3.00e-58 219.00
IUUC-Ogl-077229 Oryza glaberrima 35.17 2.00e-59 223.00
IUUC-Ogu-078977 Oryza glumaepatula 30.84 2.00e-43 169.00
IUUC-Oin-079683 Oryza indica 35.17 6.00e-60 224.00
IUUC-Olo-080291 Oryza longistaminata 30.41 4.00e-29 121.00
IUUC-Ome-081834 Oryza meridionalis 35.41 8.00e-61 227.00
IUUC-Oni-082507 Oryza nivara 34.05 3.00e-55 209.00
IUUC-Opu-083396 Oryza punctata 35.41 2.00e-59 223.00
IUUC-Oru-085220 Oryza rufipogon 34.05 8.00e-55 207.00
IUUC-Osa-085767 Oryza sativa 35.17 6.00e-60 224.00
IUUC-Ola-087420 Oryzias latipes 74.23 0.00e+00 636.00
IUUC-Olu-087740 Ostreococcus lucimarinus 28.81 6.00e-39 154.00
IUUC-Oga-088264 Otolemur garnettii 80.38 0.00e+00 647.00
IUUC-Oar-089335 Ovis aries 81.09 0.00e+00 652.00
IUUC-Ptr-091320 Pan troglodytes 81.56 0.00e+00 635.00
IUUC-Pan-092833 Papio anubis 81.09 0.00e+00 636.00
IUUC-Psi-093504 Pelodiscus sinensis 81.32 0.00e+00 665.00
IUUC-Pma-094189 Petromyzon marinus 66.27 8.00e-161 559.00
IUUC-Pno-094929 Phaeosphaeria nodorum 26.60 1.00e-34 140.00
IUUC-Ppa-095429 Physcomitrella patens 35.68 1.00e-63 236.00
IUUC-Pfo-096337 Poecilia formosa 73.29 0.00e+00 637.00
IUUC-Pab-097571 Pongo abelii 81.09 0.00e+00 634.00
IUUC-Pop-099977 Populus trichocarpa 35.82 5.00e-63 234.00
IUUC-Pca-100394 Procavia capensis 77.02 4.00e-170 590.00
IUUC-Ppe-101848 Prunus persica 36.39 5.00e-62 231.00
IUUC-Pva-102921 Pteropus vampyrus 79.76 2.00e-96 345.00
IUUC-Pgr-103637 Puccinia graminis 28.48 2.00e-37 149.00
IUUC-Ptt-103781 Puccinia triticina 28.69 8.00e-38 151.00
IUUC-Pte-104135 Pyrenophora teres 27.70 2.00e-36 148.00
IUUC-Pyt-104609 Pyrenophora triticirepentis 27.67 6.00e-36 144.00
IUUC-Rno-105114 Rattus norvegicus 80.38 0.00e+00 652.00
IUUC-Sce-106401 Saccharomyces cerevisiae 30.70 9.00e-42 164.00
IUUC-Sha-107122 Sarcophilus harrisii 77.86 2.00e-178 618.00
IUUC-Sja-107766 Schizosaccharomyces japonicus 31.54 3.00e-48 185.00
IUUC-Spo-108134 Schizosaccharomyces pombe 29.44 1.00e-37 150.00
IUUC-Ssl-108398 Sclerotinia sclerotiorum 28.81 2.00e-37 149.00
IUUC-Smo-108720 Selaginella moellendorffii 31.84 3.00e-51 195.00
IUUC-Sit-110311 Setaria italica 36.67 9.00e-58 217.00
IUUC-Sly-111178 Solanum lycopersicum 35.24 2.00e-57 216.00
IUUC-Stu-112778 Solanum tuberosum 35.32 6.00e-60 224.00
IUUC-Sar-113596 Sorex araneus 65.48 1.00e-142 499.00
IUUC-Sbi-114193 Sorghum bicolor 36.25 3.00e-56 212.00
IUUC-Sre-115002 Sporisorium reilianum 26.16 3.00e-13 69.70
IUUC-Ssc-116066 Sus scrofa 80.38 0.00e+00 645.00
IUUC-Tgu-117048 Taeniopygia guttata 78.36 2.00e-168 585.00
IUUC-Tsy-119573 Tarsius syrichta 52.39 5.00e-108 384.00
IUUC-Tni-119820 Tetraodon nigroviridis 74.76 0.00e+00 635.00
IUUC-Tca-121605 Theobroma cacao 36.06 1.00e-59 223.00
IUUC-Tre-121947 Trichoderma reesei 27.02 5.00e-34 138.00
IUUC-Tvi-122481 Trichoderma virens 27.52 2.00e-36 146.00
IUUC-Tae-125861 Triticum aestivum 34.29 2.00e-60 226.00
IUUC-Tur-126586 Triticum urartu 34.78 9.00e-57 213.00
IUUC-Tme-126900 Tuber melanosporum 31.21 3.00e-47 182.00
IUUC-Tbe-127736 Tupaia belangeri 61.81 2.00e-124 439.00
IUUC-Ttr-129041 Tursiops truncatus 69.50 7.00e-160 556.00
IUUC-Uma-129628 Ustilago maydis 26.07 2.00e-07 50.80
IUUC-Vpa-130260 Vicugna pacos 81.09 0.00e+00 654.00
IUUC-Vvi-131009 Vitis vinifera 35.48 2.00e-60 226.00
IUUC-Xma-133094 Xiphophorus maculatus 73.52 0.00e+00 635.00
IUUC-Yli-134531 Yarrowia lipolytica 25.65 1.00e-22 100.00
IUUC-Zma-135509 Zea mays 34.29 3.00e-57 215.00
Created Date 25-Jun-2017

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