iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045340

UUCD1 version

UUC-GoG-00646

Ensembl Protein ID

ENSGGOP00000016252.2

UniProt Accession

G3RKI4; G3RKI4_GORGO

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000016652.2	ENSGGOT00000016711.2	ENSGGOP00000016252.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-07	30.0	186	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ + f  ++  +ll+s+s+Dgt+++W++r+g++l+
   Q: 186  GHTEFVSRI-FvvPTqpGLLLSSSGDGTLRLWEYRSGRQLH 225
           677777777.78944469*******************9986 PP

Organism

Gorilla gorilla

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MAGSVGLALC GQTLVVRGGS RFLATSIASS DDDSLFIYDC SAAEKKSQEN KGEDAPLDQG 60
SGVILASTFS KSGSYFALTD DSKRLILFRT KPWQCLSVRT VARRCTALTF IASEEKVLVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTCACCGA CCGGTGCGGA CAGGAAGAGG CTCTGGGCTG GTACATGTGT ATGGCGGTGA 60
GGCGGGCGGG TACATGGCGG GCTCTGTGGG ACTGGCGTTG TGCGGCCAGA CGCTGGTGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity

KEGG

ggo:101146075

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	33.13	2.00e-10	60.10
IUUC-Apl-003975	Anas platyrhynchos	59.59	4.00e-120	424.00
IUUC-Aca-005170	Anolis carolinensis	53.93	4.00e-104	371.00
IUUC-Aly-005769	Arabidopsis lyrata	30.36	6.00e-23	101.00
IUUC-Ath-006733	Arabidopsis thaliana	35.35	3.00e-22	99.40
IUUC-Acl-008151	Aspergillus clavatus	34.93	2.00e-15	77.00
IUUC-Afl-008518	Aspergillus flavus	39.46	3.00e-17	82.40
IUUC-Afu-009102	Aspergillus fumigatus	36.47	1.00e-13	71.20
IUUC-Ani-009442	Aspergillus nidulans	27.02	2.00e-14	73.90
IUUC-Aor-010133	Aspergillus oryzae	30.23	2.00e-20	94.00
IUUC-Ate-010465	Aspergillus terreus	37.29	3.00e-14	73.20
IUUC-Ame-010613	Astyanax mexicanus	46.84	4.00e-90	325.00
IUUC-Bgr-012067	Blumeria graminis	45.88	2.00e-18	87.40
IUUC-Bta-012788	Bos taurus	77.97	0.00e+00	631.00
IUUC-Bdi-014458	Brachypodium distachyon	36.60	1.00e-17	84.30
IUUC-Bol-015373	Brassica oleracea	36.07	4.00e-22	100.00
IUUC-Bra-016644	Brassica rapa	37.78	3.00e-22	100.00
IUUC-Cpo-021963	Cavia porcellus	79.10	2.00e-169	587.00
IUUC-Csa-024148	Chlorocebus sabaeus	96.60	0.00e+00	689.00
IUUC-Cne-026834	Cryptococcus neoformans	34.44	2.00e-18	87.40
IUUC-Dre-028427	Danio rerio	47.65	8.00e-90	323.00
IUUC-Dno-028881	Dasypus novemcinctus	69.38	2.00e-158	551.00
IUUC-Dor-030522	Dipodomys ordii	74.81	1.00e-165	575.00
IUUC-Dme-032136	Drosophila melanogaster	33.33	1.00e-24	107.00
IUUC-Fca-035833	Felis catus	73.47	2.00e-166	578.00
IUUC-Fal-037497	Ficedula albicollis	57.29	2.00e-119	421.00
IUUC-Gga-040547	Gallus gallus	56.76	3.00e-124	438.00
IUUC-Gac-041761	Gasterosteus aculeatus	43.88	2.00e-81	295.00
IUUC-Gma-043941	Glycine max	35.48	6.00e-25	108.00
IUUC-Hsa-046403	Homo sapiens	97.82	0.00e+00	756.00
IUUC-Hvu-047643	Hordeum vulgare	38.76	1.00e-18	87.40
IUUC-Itr-048103	Ictidomys tridecemlineatus	80.15	1.00e-178	619.00
IUUC-Kpa-049283	Komagataella pastoris	34.59	2.00e-18	86.70
IUUC-Lch-050682	Latimeria chalumnae	48.64	4.00e-106	378.00
IUUC-Lpe-050712	Leersia perrieri	36.32	6.00e-22	98.60
IUUC-Loc-052599	Lepisosteus oculatus	51.84	1.00e-115	409.00
IUUC-Laf-054390	Loxodonta africana	78.21	3.00e-178	617.00
IUUC-Mcc-054747	Macaca mulatta	96.84	0.00e+00	723.00
IUUC-Mtr-058600	Medicago truncatula	38.76	3.00e-23	102.00
IUUC-Mla-059129	Melampsora laricipopulina	26.15	2.00e-12	66.60
IUUC-Mga-059876	Meleagris gallopavo	57.22	6.00e-123	433.00
IUUC-Mvi-060359	Microbotryum violaceum	28.80	2.00e-12	67.40
IUUC-Mmr-061518	Microcebus murinus	82.57	0.00e+00	652.00
IUUC-Mac-065625	Musa acuminata	33.86	1.00e-19	90.90
IUUC-Nfi-068402	Neosartorya fischeri	26.74	3.00e-15	76.60
IUUC-Nle-069914	Nomascus leucogenys	94.90	0.00e+00	705.00
IUUC-Ont-071555	Oreochromis niloticus	40.73	1.00e-76	280.00
IUUC-Oan-072951	Ornithorhynchus anatinus	67.61	2.00e-152	531.00
IUUC-Ocu-074679	Oryctolagus cuniculus	81.45	1.00e-170	592.00
IUUC-Oba-075355	Oryza barthii	27.55	6.00e-10	58.90
IUUC-Obr-076769	Oryza brachyantha	32.06	6.00e-23	101.00
IUUC-Ogl-077168	Oryza glaberrima	33.33	3.00e-23	102.00
IUUC-Ogu-078275	Oryza glumaepatula	27.55	5.00e-10	59.30
IUUC-Oin-079207	Oryza indica	33.33	3.00e-23	102.00
IUUC-Oni-082437	Oryza nivara	28.51	3.00e-10	59.70
IUUC-Opu-084031	Oryza punctata	33.46	1.00e-21	97.40
IUUC-Oru-084380	Oryza rufipogon	28.02	7.00e-10	58.90
IUUC-Osa-085327	Oryza sativa	33.86	4.00e-23	102.00
IUUC-Ola-086716	Oryzias latipes	43.42	5.00e-77	281.00
IUUC-Olu-087708	Ostreococcus lucimarinus	29.79	7.00e-14	71.20
IUUC-Oar-090239	Ovis aries	81.12	1.00e-173	602.00
IUUC-Ptr-090851	Pan troglodytes	99.51	0.00e+00	769.00
IUUC-Pan-092558	Papio anubis	96.38	0.00e+00	689.00
IUUC-Psi-093792	Pelodiscus sinensis	58.97	4.00e-129	454.00
IUUC-Ppa-095757	Physcomitrella patens	39.05	1.00e-19	90.90
IUUC-Pfo-096465	Poecilia formosa	41.86	1.00e-84	306.00
IUUC-Pab-097722	Pongo abelii	96.36	0.00e+00	737.00
IUUC-Pop-098979	Populus trichocarpa	35.33	7.00e-19	88.20
IUUC-Pca-100753	Procavia capensis	74.74	3.00e-117	414.00
IUUC-Ppe-101515	Prunus persica	34.00	1.00e-18	87.40
IUUC-Sja-107780	Schizosaccharomyces japonicus	26.38	3.00e-14	73.20
IUUC-Spo-108251	Schizosaccharomyces pombe	28.87	2.00e-12	66.60
IUUC-Smo-108938	Selaginella moellendorffii	36.79	7.00e-23	101.00
IUUC-Sit-110020	Setaria italica	35.05	5.00e-21	95.10
IUUC-Sly-111543	Solanum lycopersicum	33.88	4.00e-21	95.90
IUUC-Stu-111925	Solanum tuberosum	32.47	4.00e-21	95.50
IUUC-Sbi-114061	Sorghum bicolor	36.67	1.00e-20	94.40
IUUC-Tgu-117321	Taeniopygia guttata	59.01	6.00e-113	400.00
IUUC-Tru-118454	Takifugu rubripes	43.97	5.00e-80	291.00
IUUC-Tni-119894	Tetraodon nigroviridis	43.64	3.00e-77	281.00
IUUC-Tca-121746	Theobroma cacao	35.26	3.00e-20	92.80
IUUC-Tae-124114	Triticum aestivum	38.20	5.00e-18	85.50
IUUC-Tur-126254	Triticum urartu	33.74	7.00e-12	64.70
IUUC-Tbe-127683	Tupaia belangeri	52.08	6.00e-59	221.00
IUUC-Ttr-129056	Tursiops truncatus	73.61	2.00e-162	565.00
IUUC-Vvi-131428	Vitis vinifera	36.27	1.00e-21	97.40
IUUC-Xma-133605	Xiphophorus maculatus	42.16	3.00e-85	308.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence