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Tag Content
iUUCD ID IUUC-Oar-090239
Ensembl Protein ID ENSOARP00000011719.1
UniProt Accession W5PMP4; W5PMP4_SHEEP
Genbank Protein ID ENSOARP00000011719
Protein Name tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4
Genbank Nucleotide ID AMGL01012017
Gene Name WDR4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOARG00000010926.1 ENSOART00000011885.1 ENSOARP00000011717.1
ENSOARG00000010926.1 ENSOART00000011887.1 ENSOARP00000011719.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.00e-06 29.1 187 226
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ + f   +   ll+s+s+D t+++W++r+g+ l+
   Q: 187  GHTEFVSRI-FvvpNHpELLLSSSGDRTLRLWEYRSGRELH 226
           677777777.789544799******************9876 PP
   
Organism Ovis aries
Functional Description
(View)

Functional Description


     Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
 Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Protein Sequence
(Fasta)
MASSVGLALC GHALVVRGGS RLLATSTSSS DDDSLFIYDC SAAEKKSQEH KGEDGQPVDQ 60
GSDTVLASTF SKSGSYFVLT DDSKRLILFR TNPWQCLSVR TVVRRCTALT FTASEEKILV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oar-090239|E3,WD_repeat|Ovis aries
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCGAGTT CTGTGGGGTT GGCTCTGTGC GGGCATGCGC TGGTGGTTCG GGGCGGTAGC 60
CGGTTGCTGG CTACCTCCAC TTCGAGCAGG TGAGGGGTCG TTCTGGAACA GAAGACCAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oar-090239|E3,WD_repeat|Ovis aries
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000556 Aegilops tauschii 27.47 4.00e-13 69.30
IUUC-Apl-003975 Anas platyrhynchos 59.29 3.00e-121 428.00
IUUC-Aca-005170 Anolis carolinensis 55.16 8.00e-103 367.00
IUUC-Aly-005769 Arabidopsis lyrata 30.20 2.00e-24 106.00
IUUC-Ath-006733 Arabidopsis thaliana 30.13 3.00e-23 102.00
IUUC-Acl-008151 Aspergillus clavatus 38.36 5.00e-16 79.00
IUUC-Afl-008518 Aspergillus flavus 33.15 3.00e-17 82.40
IUUC-Afu-009102 Aspergillus fumigatus 34.71 6.00e-14 72.40
IUUC-Ani-009442 Aspergillus nidulans 28.85 4.00e-16 79.30
IUUC-Aor-010133 Aspergillus oryzae 28.49 7.00e-20 91.70
IUUC-Ate-010465 Aspergillus terreus 39.83 9.00e-16 78.20
IUUC-Ame-010613 Astyanax mexicanus 45.09 2.00e-86 312.00
IUUC-Bgr-012067 Blumeria graminis 27.24 4.00e-19 89.70
IUUC-Bta-012788 Bos taurus 97.85 0.00e+00 728.00
IUUC-Bdi-014458 Brachypodium distachyon 31.05 1.00e-18 87.80
IUUC-Bol-016398 Brassica oleracea 39.23 3.00e-25 109.00
IUUC-Bra-016644 Brassica rapa 39.56 2.00e-24 108.00
IUUC-Cpo-021963 Cavia porcellus 78.31 4.00e-166 577.00
IUUC-Csa-024148 Chlorocebus sabaeus 81.45 4.00e-156 544.00
IUUC-Cne-026834 Cryptococcus neoformans 35.26 3.00e-20 93.20
IUUC-Dre-028427 Danio rerio 45.91 9.00e-91 327.00
IUUC-Dno-028881 Dasypus novemcinctus 70.94 5.00e-145 507.00
IUUC-Dor-030522 Dipodomys ordii 73.96 3.00e-157 548.00
IUUC-Dme-032136 Drosophila melanogaster 36.31 1.00e-23 103.00
IUUC-Fca-035833 Felis catus 82.54 2.00e-165 575.00
IUUC-Fal-037497 Ficedula albicollis 58.33 9.00e-119 419.00
IUUC-Gga-040547 Gallus gallus 57.72 5.00e-121 427.00
IUUC-Gac-041761 Gasterosteus aculeatus 43.50 6.00e-79 287.00
IUUC-Gma-043722 Glycine max 35.00 2.00e-19 90.10
IUUC-Ggo-045340 Gorilla gorilla 81.18 4.00e-164 570.00
IUUC-Hsa-046403 Homo sapiens 80.65 7.00e-163 566.00
IUUC-Hvu-047643 Hordeum vulgare 31.45 2.00e-21 96.70
IUUC-Itr-048103 Ictidomys tridecemlineatus 79.57 3.00e-170 590.00
IUUC-Kpa-049283 Komagataella pastoris 31.21 9.00e-18 84.30
IUUC-Lch-050682 Latimeria chalumnae 53.66 1.00e-110 392.00
IUUC-Lpe-050712 Leersia perrieri 31.56 4.00e-25 108.00
IUUC-Loc-052599 Lepisosteus oculatus 49.87 1.00e-105 376.00
IUUC-Laf-054390 Loxodonta africana 77.69 2.00e-166 578.00
IUUC-Mcc-054747 Macaca mulatta 80.38 3.00e-160 557.00
IUUC-Mtr-058600 Medicago truncatula 38.42 9.00e-24 104.00
IUUC-Mla-059129 Melampsora laricipopulina 25.64 2.00e-12 66.20
IUUC-Mga-059876 Meleagris gallopavo 58.82 6.00e-122 430.00
IUUC-Mvi-060359 Microbotryum violaceum 31.65 3.00e-12 67.00
IUUC-Mmr-061518 Microcebus murinus 77.69 7.00e-161 560.00
IUUC-Mac-065417 Musa acuminata 29.18 7.00e-21 94.70
IUUC-Nfi-068402 Neosartorya fischeri 29.36 6.00e-14 72.00
IUUC-Nle-069914 Nomascus leucogenys 79.57 2.00e-156 545.00
IUUC-Ont-071555 Oreochromis niloticus 42.11 7.00e-77 281.00
IUUC-Oan-072951 Ornithorhynchus anatinus 66.39 3.00e-138 484.00
IUUC-Ocu-074679 Oryctolagus cuniculus 79.84 2.00e-163 568.00
IUUC-Oba-075355 Oryza barthii 26.53 3.00e-13 70.10
IUUC-Obr-076769 Oryza brachyantha 33.47 7.00e-26 111.00
IUUC-Ogl-077168 Oryza glaberrima 32.40 1.00e-25 110.00
IUUC-Ogu-078275 Oryza glumaepatula 25.41 4.00e-13 69.30
IUUC-Oin-079207 Oryza indica 32.40 1.00e-25 110.00
IUUC-Oni-082437 Oryza nivara 27.31 2.00e-12 66.60
IUUC-Opu-084031 Oryza punctata 32.16 2.00e-23 103.00
IUUC-Oru-084380 Oryza rufipogon 26.53 7.00e-13 68.60
IUUC-Osa-085327 Oryza sativa 32.40 3.00e-25 109.00
IUUC-Ola-086716 Oryzias latipes 42.86 4.00e-75 275.00
IUUC-Olu-087708 Ostreococcus lucimarinus 29.95 4.00e-14 72.40
IUUC-Ptr-090851 Pan troglodytes 81.18 5.00e-164 570.00
IUUC-Pan-092558 Papio anubis 80.75 3.00e-154 538.00
IUUC-Psi-093792 Pelodiscus sinensis 58.70 2.00e-129 455.00
IUUC-Ppa-095757 Physcomitrella patens 30.48 3.00e-20 92.80
IUUC-Pfo-096465 Poecilia formosa 43.27 2.00e-80 292.00
IUUC-Pab-097722 Pongo abelii 79.95 6.00e-162 563.00
IUUC-Pop-098979 Populus trichocarpa 34.95 1.00e-20 94.40
IUUC-Pca-100753 Procavia capensis 75.81 1.00e-109 389.00
IUUC-Ppe-101515 Prunus persica 29.67 3.00e-20 92.80
IUUC-Sja-107780 Schizosaccharomyces japonicus 28.63 5.00e-15 75.50
IUUC-Spo-108251 Schizosaccharomyces pombe 25.95 3.00e-13 69.30
IUUC-Smo-108938 Selaginella moellendorffii 37.82 9.00e-23 101.00
IUUC-Sit-110020 Setaria italica 30.12 2.00e-22 100.00
IUUC-Sly-111543 Solanum lycopersicum 28.48 8.00e-25 108.00
IUUC-Stu-111925 Solanum tuberosum 29.13 2.00e-24 106.00
IUUC-Sbi-114061 Sorghum bicolor 30.43 1.00e-22 100.00
IUUC-Tgu-117321 Taeniopygia guttata 57.82 2.00e-109 389.00
IUUC-Tru-118454 Takifugu rubripes 44.50 3.00e-78 285.00
IUUC-Tni-119894 Tetraodon nigroviridis 43.39 6.00e-71 261.00
IUUC-Tca-121746 Theobroma cacao 34.05 2.00e-20 93.20
IUUC-Tae-124114 Triticum aestivum 31.45 9.00e-22 97.80
IUUC-Tur-126254 Triticum urartu 26.45 3.00e-14 72.40
IUUC-Tbe-127683 Tupaia belangeri 50.63 3.00e-52 199.00
IUUC-Ttr-129056 Tursiops truncatus 83.06 3.00e-174 604.00
IUUC-Vvi-131428 Vitis vinifera 36.02 5.00e-23 102.00
IUUC-Xma-133605 Xiphophorus maculatus 43.27 4.00e-80 291.00
Created Date 25-Jun-2017

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