iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-119894

UUCD1 version

UUC-TeN-00669

Ensembl Protein ID

ENSTNIP00000006871.1

UniProt Accession

H3CF47; H3CF47_TETNG

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Gene Name

wdr4; WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000004246.1	ENSTNIT00000007023.1	ENSTNIP00000006871.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-08	35.1	155	194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+  v++l +   +  + l+sGs+Dgtik+WD+ +g+ l+s
   Q: 155  HQQFVSAL-LvppTHpCWLLSGSGDGTIKLWDYERGRRLQS 194
           55555555.257433578***************99998775 PP

Organism

Tetraodon nigroviridis

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

FVFDCSSAER KPKSSKDENS GAAEETGSDR ILAFCTSPSG KLLALTDDSK RLVLLTCEPS 60
WRRLSTRRFV ARRSTSLHFT NAEDELLVAD KSGDVYPFSV ADAGGGELLM GHLSMLLAVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTGTGTTCG ACTGCAGCTC AGCAGAGAGG AAACCAAAAA GCTCCAAGGA TGAAAACAGG 60
TGAAAAATCA CGTCGGGACA ACGATGATGA CGTCAGTCTG TTCTGTTCAA AGAGCTCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0036265--P:RNA (guanine-N7)-methylation
GO:0030488--P:tRNA methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	29.57	5.00e-07	48.90
IUUC-Atr-002431	Amborella trichopoda	32.87	2.00e-11	60.80
IUUC-Apl-003975	Anas platyrhynchos	42.44	1.00e-71	263.00
IUUC-Aca-005170	Anolis carolinensis	38.57	1.00e-56	213.00
IUUC-Aly-005769	Arabidopsis lyrata	30.17	8.00e-22	97.80
IUUC-Ath-006733	Arabidopsis thaliana	31.60	2.00e-21	97.10
IUUC-Acl-008151	Aspergillus clavatus	27.06	1.00e-14	74.30
IUUC-Afl-008518	Aspergillus flavus	33.33	4.00e-18	85.10
IUUC-Afu-009102	Aspergillus fumigatus	29.10	3.00e-16	79.70
IUUC-Ani-009442	Aspergillus nidulans	34.21	7.00e-15	75.10
IUUC-Aor-010133	Aspergillus oryzae	30.13	3.00e-18	86.70
IUUC-Ate-010465	Aspergillus terreus	34.46	1.00e-17	84.30
IUUC-Ame-010613	Astyanax mexicanus	50.26	5.00e-94	337.00
IUUC-Bgr-012067	Blumeria graminis	36.54	4.00e-19	89.00
IUUC-Bta-012788	Bos taurus	43.08	2.00e-68	253.00
IUUC-Bdi-014458	Brachypodium distachyon	32.91	3.00e-15	75.90
IUUC-Bol-016398	Brassica oleracea	34.03	7.00e-23	101.00
IUUC-Bra-016644	Brassica rapa	32.91	3.00e-24	107.00
IUUC-Cpo-021963	Cavia porcellus	43.79	9.00e-67	246.00
IUUC-Csa-024148	Chlorocebus sabaeus	43.90	7.00e-62	230.00
IUUC-Cne-026834	Cryptococcus neoformans	33.17	4.00e-21	95.90
IUUC-Dre-028427	Danio rerio	51.86	3.00e-96	345.00
IUUC-Dno-028881	Dasypus novemcinctus	38.76	2.00e-56	212.00
IUUC-Dor-030522	Dipodomys ordii	43.12	7.00e-68	250.00
IUUC-Dme-032136	Drosophila melanogaster	35.82	1.00e-23	103.00
IUUC-Fca-035833	Felis catus	44.30	7.00e-69	253.00
IUUC-Fal-037497	Ficedula albicollis	41.50	8.00e-73	266.00
IUUC-Gga-040547	Gallus gallus	42.53	5.00e-72	264.00
IUUC-Gac-041761	Gasterosteus aculeatus	57.35	1.00e-105	375.00
IUUC-Gma-043722	Glycine max	30.03	6.00e-21	94.70
IUUC-Ggo-045340	Gorilla gorilla	45.06	4.00e-65	241.00
IUUC-Hsa-046403	Homo sapiens	45.64	8.00e-66	244.00
IUUC-Hvu-047643	Hordeum vulgare	32.34	1.00e-15	77.40
IUUC-Itr-048103	Ictidomys tridecemlineatus	45.27	5.00e-75	274.00
IUUC-Kpa-049283	Komagataella pastoris	33.33	2.00e-19	90.10
IUUC-Lch-050682	Latimeria chalumnae	44.02	7.00e-76	277.00
IUUC-Lpe-050712	Leersia perrieri	34.05	1.00e-21	97.40
IUUC-Loc-052599	Lepisosteus oculatus	48.15	1.00e-91	329.00
IUUC-Laf-054390	Loxodonta africana	44.19	8.00e-69	254.00
IUUC-Mcc-054747	Macaca mulatta	45.93	5.00e-66	244.00
IUUC-Mtr-058600	Medicago truncatula	35.00	3.00e-23	102.00
IUUC-Mla-059129	Melampsora laricipopulina	29.59	6.00e-14	71.20
IUUC-Mga-059876	Meleagris gallopavo	41.16	1.00e-71	263.00
IUUC-Mvi-060359	Microbotryum violaceum	29.70	5.00e-13	69.30
IUUC-Mmr-061518	Microcebus murinus	43.90	2.00e-66	246.00
IUUC-Mac-065625	Musa acuminata	31.58	1.00e-18	87.80
IUUC-Nfi-068402	Neosartorya fischeri	31.54	2.00e-17	83.20
IUUC-Nle-069914	Nomascus leucogenys	43.60	1.00e-60	227.00
IUUC-Ont-071555	Oreochromis niloticus	58.03	5.00e-108	384.00
IUUC-Oan-072951	Ornithorhynchus anatinus	42.41	3.00e-71	262.00
IUUC-Ocu-074679	Oryctolagus cuniculus	43.19	7.00e-60	224.00
IUUC-Oba-075355	Oryza barthii	25.93	1.00e-10	60.80
IUUC-Obr-076769	Oryza brachyantha	33.33	1.00e-23	104.00
IUUC-Ogl-077168	Oryza glaberrima	31.71	1.00e-22	100.00
IUUC-Ogu-078275	Oryza glumaepatula	25.39	1.00e-10	61.20
IUUC-Oin-079207	Oryza indica	31.71	1.00e-22	100.00
IUUC-Oni-082437	Oryza nivara	24.72	1.00e-10	60.80
IUUC-Opu-084031	Oryza punctata	31.27	1.00e-21	97.80
IUUC-Oru-084380	Oryza rufipogon	25.78	2.00e-10	60.50
IUUC-Osa-085327	Oryza sativa	31.71	2.00e-22	100.00
IUUC-Ola-086716	Oryzias latipes	53.28	4.00e-93	334.00
IUUC-Olu-087708	Ostreococcus lucimarinus	28.47	4.00e-13	68.90
IUUC-Oar-090239	Ovis aries	44.70	1.00e-69	256.00
IUUC-Ptr-090851	Pan troglodytes	45.06	5.00e-65	241.00
IUUC-Pan-092558	Papio anubis	42.64	3.00e-61	228.00
IUUC-Psi-093792	Pelodiscus sinensis	39.88	2.00e-66	245.00
IUUC-Ppa-095757	Physcomitrella patens	32.03	4.00e-20	92.40
IUUC-Pfo-096465	Poecilia formosa	54.87	5.00e-103	367.00
IUUC-Pab-097722	Pongo abelii	44.79	3.00e-66	245.00
IUUC-Pop-098979	Populus trichocarpa	32.63	1.00e-19	90.50
IUUC-Pca-100753	Procavia capensis	41.11	5.00e-45	174.00
IUUC-Ppe-101515	Prunus persica	33.48	4.00e-20	92.40
IUUC-Sja-107780	Schizosaccharomyces japonicus	26.72	1.00e-12	67.80
IUUC-Spo-108251	Schizosaccharomyces pombe	27.95	8.00e-17	81.30
IUUC-Smo-108938	Selaginella moellendorffii	33.98	5.00e-22	98.60
IUUC-Sit-110020	Setaria italica	33.91	3.00e-21	96.30
IUUC-Sly-111543	Solanum lycopersicum	32.11	1.00e-21	97.40
IUUC-Stu-111925	Solanum tuberosum	31.06	4.00e-21	95.50
IUUC-Sbi-114061	Sorghum bicolor	32.82	2.00e-21	97.10
IUUC-Tgu-117321	Taeniopygia guttata	42.98	4.00e-65	241.00
IUUC-Tru-118454	Takifugu rubripes	75.00	1.00e-135	476.00
IUUC-Tca-121746	Theobroma cacao	33.33	1.00e-23	104.00
IUUC-Tae-123054	Triticum aestivum	31.91	1.00e-16	80.90
IUUC-Tur-126254	Triticum urartu	28.40	4.00e-08	52.00
IUUC-Tbe-127683	Tupaia belangeri	55.43	3.00e-24	105.00
IUUC-Ttr-129056	Tursiops truncatus	41.25	2.00e-61	229.00
IUUC-Vvi-131428	Vitis vinifera	33.05	4.00e-18	85.50
IUUC-Xma-133605	Xiphophorus maculatus	55.43	1.00e-104	373.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence