iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007634

Ensembl Protein ID

AT3G15880.2

UniProt Accession

Q27GK7; B9DHS5; Q0WMG2; Q3EB60; Q9LVZ2; TPR4_ARATH

Genbank Protein ID

BAB02318.1; AEE75740.1; AEE75741.1; ANM63812.1; BAF01694.1; BAH20292.1

Protein Name

Topless-related protein 4; WUS-interacting protein 2

Genbank Nucleotide ID

AB017071; CP002686; CP002686; CP002686; AY039963; AK317630

Gene Name

TPR4; WSIP2; At3g15880; MSJ11.27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G15880	AT3G15880.1	AT3G15880.1
AT3G15880	AT3G15880.2	AT3G15880.2
AT3G15880	AT3G15880.3	AT3G15880.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-21	75.7	463	503
UBD/Beta-Prp	2.90e-43	149.0	357	541

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tl.lvsGsdDgtikvWDlrtgvllks 38
           H++ v++laf  ++  l +v+++ D+tikvWD  tg++l++
   Q: 463  HAGNVNDLAFsqPNqQLcVVTCGEDKTIKVWDAVTGNKLHT 503
           99********99665444799***************99875 PP

UBD/Beta-Prp

   S: 94   edsvlslsfsp.sgdklvsGshdrtirvwdletgqclee..................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkll 172
            + + s++f+p ++  l++G++   i +w++ ++++l +                  + s+ +++vn vv++pdg ll  +    +v +++   g+ l
   Q: 357  GSAIKSMDFHPvQQTMLLVGTNLGDIAIWEVGSREKLVSrsfkvwdlatctvnlqasLASEYTAAVNRVVWSPDGGLLGVAYSKHIVHIYSYHGGEDL 454
           567899*****888*******************************************************************************99999 PP
   S: 173  rtl..tgghtdsvyslsfds.ng.kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriW...d 250
           r      +h + v+ l+f++ n+  ++v++++d+t+k+wd  tg+ ++t++gh+++v+sv  +  +n +++ s++ Dg i+ W   +
   Q: 455  RNHleIDAHAGNVNDLAFSQpNQqLCVVTCGEDKTIKVWDAVTGNKLHTFEGHEAPVYSVCPHqkENIQFIFSTAVDGKIKAWlydN 541
           99878556*********87624446789********************************9995567778*************6643 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Transcriptional corepressor. Negative regulator of jasmonate responses (By similarity).

Protein Sequence
(Fasta)

MSSLSRELVF LILQFLDEEK FKDTVHRLEK ESGFFFNMRY FEDSVTAGEW DDVEKYLSGF 60
TKVDDNRYSM KIFFEIRKQK YLEALDKKDH AKAVDILVKE LKVFSTFNEE LFKEITMLLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGCCATAAA TAGCCCCCAC GTCTCTCTCT CTCTCTTCTC CAAAGTCTTC TTCTTCTTCT 60
TCTTCTTCTT CCTCTTCTTC CTCTCTGCTT TGTCTCTCTC CTTCTTCAAA GTCAAAATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR006595--CTLH_C
IPR006594--LisH
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0010072--P:primary shoot apical meristem specification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

ath:AT3G15880

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006463	Arabidopsis lyrata	98.41	0.00e+00	2153.00
IUUC-Bol-015812	Brassica oleracea	94.36	0.00e+00	2165.00
IUUC-Bra-016964	Brassica rapa	93.74	0.00e+00	2124.00
IUUC-Gma-043971	Glycine max	74.98	0.00e+00	1702.00
IUUC-Mtr-058586	Medicago truncatula	74.78	0.00e+00	1703.00
IUUC-Pop-099918	Populus trichocarpa	74.49	0.00e+00	1692.00
IUUC-Ppe-101506	Prunus persica	75.45	0.00e+00	1714.00
IUUC-Sly-111451	Solanum lycopersicum	76.46	0.00e+00	1757.00
IUUC-Stu-112409	Solanum tuberosum	71.55	0.00e+00	1622.00
IUUC-Tca-121699	Theobroma cacao	74.89	0.00e+00	1739.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence