iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pgr-103492

Ensembl Protein ID

EFP74652

UniProt Accession

E3JQC3; E3JQC3_PUCGT

Genbank Protein ID

EFP74652.2

Protein Name

Ubiquitin-activating enzyme E1 C

Genbank Nucleotide ID

DS178262

Gene Name

PGTG_00608

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PGTG_00608	EFP74652	EFP74652

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.20e-78	262.3	288	477

Active Site

Position(s)	Description	Evidence
461	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 17   ksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkfdvVvlal 117
           k++k+l++GagglGcE+l nL+l+G+  i+v+Dmdt+++snlnrqFLfr++d+g++KAevaa+++  ++p+v+v++h ++i+++++   F+  f++Vv++l
   Q: 288  KTCKILVIGAGGLGCEILQNLALLGFADIHVIDMDTIDISNLNRQFLFREKDIGQPKAEVAAKFIMARVPQVKVTPHYCKIQDKDDA--FYMMFNLVVCGL 386
           799*********************************************************************************999..************ PP
   S: 118  dnrearrkvnrlclna........rvpliesgtl........GllGqvrviikgltecyscsd..dppqktiPfctlketpnaaehtiewa 190
           d++earr++n  ++n+         +pli++gt+        G++Gq rvi++ +t cy+cs     pq+ +P+ct+++tp+ +eh+iewa
   Q: 387  DSVEARRWINATLVNLvdpenpesLKPLIDGGTEgmlegddiGFKGQSRVILPTITSCYECSLdmLTPQTVFPICTIANTPRLPEHCIEWA 477
           ************************677777776622222222799******************88899*********************** PP

Organism

Puccinia graminis

Protein Sequence
(Fasta)

MTGRQPGNHP QYPYYPTQNS NPNPYPNRWP PPPQLTREQH LENQRRSEER RRRYQESLPA 60
PHERHRPQRH HEEQRRYNHE IQQQNQLKKQ QEKEERQRKH QEKQHQEQLA KQERKRQNEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGGAA GACAGCCTGG AAACCATCCA CAATACCCAT ACTACCCCAC CCAAAACAGC 60
AACCCAAACC CATATCCAAA TCGATGGCCA CCACCACCCC AGTTAACACG CGAACAACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

pgr:PGTG_00608

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence