iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012425

UUCD1 version

UUC-BoT-00877

Ensembl Protein ID

ENSBTAP00000007571.5

UniProt Accession

Q28009; Q0P5J2; FUS_BOVIN

Genbank Protein ID

AAC13543.1; AAI19966.1

Protein Name

RNA-binding protein FUS; Protein pigpen

Genbank Nucleotide ID

U26024; BC119965

Gene Name

FUS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000005757.5	ENSBTAT00000007571.5	ENSBTAP00000007571.5

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	100.00	6.00e-76	282.00	IUUC-Hsa-046885

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Functional Description
(View)

Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity (By similarity).

Protein Sequence
(Fasta)

MASNDYTQQA TQSYGAYPTQ PGQGYSQQSN QPYGQQSYGG YGQSTDTSGY GQSSYSGSYG 60
QTQNSYSTQS APQGYGSAGG YGSSQSSQSS YGQQSSYPGY GQQPAPSSTS GSYGSSSQSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCTCTGTA GTGTTGGAAT CTTGTTGCTT GTCGGCCTGT GCGCGCGTGC GCGGACATGG 60
CCTCAAACGG TATGTAAGGG CGCGAGGCGG TGGTGGCGCG CCGGCCCCGG ATCTCATTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0488--Methylation
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0694--RNA-binding
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034459--FUS
IPR012677--Nucleotide-bd_a/b_plait
IPR000504--RRM_dom
IPR001876--Znf_RanBP2

PROSITE

PS50102--RRM
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF00076--RRM_1
PF00641--zf-RanBP

SMART

SM00360--RRM
SM00547--ZnF_RBZ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0000166--F:nucleotide binding
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding

KEGG

bta:280796

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001251	Ailuropoda melanoleuca	100.00	2.00e-60	226.00
IUUC-Cel-018311	Caenorhabditis elegans	39.56	1.00e-12	67.40
IUUC-Cja-019524	Callithrix jacchus	100.00	4.00e-77	281.00
IUUC-Cfa-020792	Canis familiaris	99.25	8.00e-76	277.00
IUUC-Cho-024940	Choloepus hoffmanni	96.63	6.00e-66	244.00
IUUC-Cin-025316	Ciona intestinalis	57.32	2.00e-24	104.00
IUUC-Dno-029527	Dasypus novemcinctus	99.62	8.00e-78	284.00
IUUC-Dor-031027	Dipodomys ordii	100.00	4.00e-61	228.00
IUUC-Dme-031985	Drosophila melanogaster	50.00	1.00e-22	100.00
IUUC-Ete-033069	Echinops telfairi	92.02	4.00e-50	191.00
IUUC-Eeu-034445	Erinaceus europaeus	100.00	2.00e-77	283.00
IUUC-Gac-042021	Gasterosteus aculeatus	84.44	2.00e-42	166.00
IUUC-Hsa-046885	Homo sapiens	100.00	1.00e-77	283.00
IUUC-Itr-048085	Ictidomys tridecemlineatus	100.00	6.00e-72	265.00
IUUC-Laf-053348	Loxodonta africana	93.61	9.00e-75	274.00
IUUC-Meu-056142	Macropus eugenii	97.87	2.00e-79	290.00
IUUC-Mmr-060597	Microcebus murinus	100.00	3.00e-77	282.00
IUUC-Mdo-062406	Monodelphis domestica	98.87	1.00e-85	310.00
IUUC-Mmu-063450	Mus musculus	100.00	2.00e-72	266.00
IUUC-Mpu-066821	Mustela putorius furo	99.62	4.00e-77	282.00
IUUC-Mlu-067643	Myotis lucifugus	99.25	6.00e-79	288.00
IUUC-Nle-069461	Nomascus leucogenys	100.00	1.00e-77	283.00
IUUC-Oan-073686	Ornithorhynchus anatinus	98.40	9.00e-71	261.00
IUUC-Oar-090388	Ovis aries	100.00	5.00e-72	263.00
IUUC-Ptr-091157	Pan troglodytes	100.00	1.00e-77	284.00
IUUC-Pab-098761	Pongo abelii	86.42	1.00e-54	207.00
IUUC-Pca-100284	Procavia capensis	100.00	2.00e-52	199.00
IUUC-Pva-102411	Pteropus vampyrus	98.86	4.00e-85	308.00
IUUC-Pgr-103625	Puccinia graminis	25.27	1.60e-02	33.90
IUUC-Rno-105994	Rattus norvegicus	99.47	6.00e-72	265.00
IUUC-Ssc-116079	Sus scrofa	99.62	9.00e-78	284.00
IUUC-Tsy-119631	Tarsius syrichta	91.98	2.00e-69	256.00
IUUC-Tni-119747	Tetraodon nigroviridis	70.77	2.00e-59	223.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence