iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098110

Ensembl Protein ID

ENSPPYP00000013956.2

UniProt Accession

H2P6I0; H2P6I0_PONAB

Genbank Protein ID

ENSPPYP00000013956

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01067464

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000012496.2	ENSPPYT00000014522.2	ENSPPYP00000013956.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-29	100.6	567	599
UBD/Beta-Prp	1.40e-45	155.9	563	777

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHtd v++la+   +  +l+s+s Dgt+++W+++
   Q: 567  GHTDAVWGLAYsaaH-QRLLSCSADGTLRLWNTT 599
           8**********9853.89**************76 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk......ghedsvlslsfspsgdklvsGshdrtirvwdletgqc 128
             l gh+++v+ + +s   + l+++s D+t+++w+     +  ++       g  +sv ++s++p  +++v+  +  +  ++++et+q 
   Q: 563  GPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFndtkelGIPASVDLVSSDP--SHMVASFSKGYTSIFNMETQQR 649
           5689******************************7775555444442666667777777788888..888888889************* PP
   S: 129  lee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           + +      t ++ +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l++
   Q: 650  ILTlesnvdTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLES 737
           ***9999998888888999999***99**************************98.********************************* PP
   S: 212  gecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 738  KTCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 777
           ***********999999******************97655 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MDEQAGPGVF FSNNHPGAGG AKGLGPLAEA AAAGDGAAAA GAARAQYSLP GILHFLQHEW 60
ARFEVERAQW EVERAELQAQ IAFLQGERKG QENLKKDLVR RIKMLEYALK QERAKYHKLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATTTCCCGG CCCGTCACGG GCTCGGCCGG CCCCCGCGCC CAGGCGGCTG CTCCCTGCTG 60
ACTGGGGTGT GGGCGGGAGC GGCGGAGGGA GGAGGAGGTG CTGCTTGCCG CCGCTGTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR013258--Striatin_N
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	97.96	0.00e+00	1364.00
IUUC-Apl-003927	Anas platyrhynchos	88.23	0.00e+00	1127.00
IUUC-Aca-004933	Anolis carolinensis	81.15	0.00e+00	1155.00
IUUC-Ate-010457	Aspergillus terreus	26.24	3.00e-29	124.00
IUUC-Ame-010997	Astyanax mexicanus	73.65	0.00e+00	1075.00
IUUC-Bta-013077	Bos taurus	97.56	0.00e+00	1384.00
IUUC-Cja-018973	Callithrix jacchus	99.49	0.00e+00	1404.00
IUUC-Cfa-020988	Canis familiaris	94.31	0.00e+00	1233.00
IUUC-Cpo-022496	Cavia porcellus	97.31	0.00e+00	1386.00
IUUC-Csa-023829	Chlorocebus sabaeus	98.72	0.00e+00	1394.00
IUUC-Dre-028560	Danio rerio	69.17	0.00e+00	974.00
IUUC-Dno-029742	Dasypus novemcinctus	91.92	0.00e+00	1315.00
IUUC-Dor-030721	Dipodomys ordii	89.62	0.00e+00	1265.00
IUUC-Eca-033760	Equus caballus	97.87	0.00e+00	1288.00
IUUC-Eeu-034953	Erinaceus europaeus	97.40	0.00e+00	754.00
IUUC-Fca-036530	Felis catus	97.30	0.00e+00	1289.00
IUUC-Fal-037353	Ficedula albicollis	81.65	0.00e+00	896.00
IUUC-Gga-040132	Gallus gallus	88.03	0.00e+00	1140.00
IUUC-Gac-041713	Gasterosteus aculeatus	73.58	0.00e+00	1060.00
IUUC-Ggo-045455	Gorilla gorilla	87.37	0.00e+00	1199.00
IUUC-Hsa-046415	Homo sapiens	99.87	0.00e+00	1406.00
IUUC-Lch-050475	Latimeria chalumnae	81.65	0.00e+00	1186.00
IUUC-Loc-051859	Lepisosteus oculatus	77.47	0.00e+00	1133.00
IUUC-Laf-053537	Loxodonta africana	96.92	0.00e+00	1391.00
IUUC-Mcc-055817	Macaca mulatta	98.47	0.00e+00	1393.00
IUUC-Meu-055946	Macropus eugenii	70.04	0.00e+00	910.00
IUUC-Mga-059694	Meleagris gallopavo	88.07	0.00e+00	1117.00
IUUC-Mmr-060768	Microcebus murinus	98.46	0.00e+00	1414.00
IUUC-Mdo-061901	Monodelphis domestica	86.80	0.00e+00	1312.00
IUUC-Mmu-064154	Mus musculus	96.92	0.00e+00	1374.00
IUUC-Mpu-065827	Mustela putorius furo	93.08	0.00e+00	1377.00
IUUC-Mlu-067102	Myotis lucifugus	97.55	0.00e+00	1355.00
IUUC-Ncr-068831	Neurospora crassa	39.60	6.00e-22	99.40
IUUC-Nle-070008	Nomascus leucogenys	99.57	0.00e+00	1312.00
IUUC-Opr-071067	Ochotona princeps	61.62	4.00e-179	620.00
IUUC-Ont-072025	Oreochromis niloticus	73.29	0.00e+00	1049.00
IUUC-Oan-072950	Ornithorhynchus anatinus	91.77	0.00e+00	1167.00
IUUC-Ocu-074316	Oryctolagus cuniculus	97.16	0.00e+00	1275.00
IUUC-Ola-087279	Oryzias latipes	71.19	0.00e+00	1025.00
IUUC-Oga-088284	Otolemur garnettii	97.69	0.00e+00	1384.00
IUUC-Oar-090304	Ovis aries	98.08	0.00e+00	1389.00
IUUC-Ptr-091052	Pan troglodytes	100.00	0.00e+00	1408.00
IUUC-Pan-092270	Papio anubis	92.97	0.00e+00	1352.00
IUUC-Psi-093907	Pelodiscus sinensis	88.33	0.00e+00	1050.00
IUUC-Pfo-097042	Poecilia formosa	72.44	0.00e+00	1131.00
IUUC-Pca-100266	Procavia capensis	85.23	0.00e+00	992.00
IUUC-Pva-102824	Pteropus vampyrus	95.51	0.00e+00	1359.00
IUUC-Pgr-103483	Puccinia graminis	36.99	1.00e-56	215.00
IUUC-Rno-105638	Rattus norvegicus	96.92	0.00e+00	1379.00
IUUC-Sha-107004	Sarcophilus harrisii	88.12	0.00e+00	1123.00
IUUC-Ssc-115280	Sus scrofa	98.33	0.00e+00	1396.00
IUUC-Tgu-116759	Taeniopygia guttata	88.92	0.00e+00	1146.00
IUUC-Tru-117944	Takifugu rubripes	73.29	0.00e+00	1055.00
IUUC-Tsy-119405	Tarsius syrichta	86.75	0.00e+00	1088.00
IUUC-Tni-120571	Tetraodon nigroviridis	72.73	0.00e+00	1062.00
IUUC-Vpa-130294	Vicugna pacos	97.29	0.00e+00	1276.00
IUUC-Xma-134233	Xiphophorus maculatus	68.50	0.00e+00	909.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence