iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045358

UUCD1 version

UUC-GoG-01037

Ensembl Protein ID

ENSGGOP00000025629.1

UniProt Accession

G3SC02; G3SC02_GORGO

Protein Name

Uncharacterized protein

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000002517.2	ENSGGOT00000022588.1	ENSGGOP00000025629.1
ENSGGOG00000002517.2	ENSGGOT00000002534.2	ENSGGOP00000002481.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.70e-138	462.7	10	421

Active Site

Position(s)	Description	Evidence
173	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 11   eaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           e  e++   +vl+vGagg+GcEllKnLvl+G+++i ++D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p+ n++a+++si++
   Q: 10   ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMN 98
           56799999********************************************************************************* PP
   S: 100  leeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtie 188
           ++++++Ff++f +V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+
   Q: 99   PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIV 187
           ***************************************************************************************** PP
   S: 189  wa.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv. 274
           wa +lfn+l++ee++++ev++  d++++e++++++++e+++++++++ ++++i++k++ak+t ++ +k ++k f++di++  ++++++ 
   Q: 188  WAkYLFNQLFGEEDADQEVSP--DRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWr 274
           *********************..799*************************************************************** PP
   S: 275  .................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaan 341
                            +  + ++++++p+ ++kd++v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aan
   Q: 275  krkppvpldwaevqsqgEETNASDQQNEPQLGLKDQQVLDVKSYarlfsKSIETLRVHLAEKGDGA---ELIWDKDDPSAMDFVTSAAN 360
           ****************999999********************************************...68****************** PP
   S: 342  lraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           lr++ +++++  ++++ik++agniipaiattnav++Gl+++E +K++sgk ++++++fl+++
   Q: 361  LRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQ 421
           **********.***********************************************9965 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MALSRGLPRE LAEAVAGGRV LVVGAGGIGC ELLKNLVLTG FSHIDLIDLD TIDVSNLNRQ 60
FLFQKKHVGR SKAQVAKESV LQFYPKANIV AYHDSIMNPD YNVEFFRQFI LVMNALDNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCCCCCAC CCGCTTCCGG CCGCGGCTCG GTTCTCCCGC CTCCGCCTCC GCCGCGGCTC 60
GTGGTTGTCC CGCCATGGCA CTGTCGCGGG GGCTGCCCCG GGAGCTGGCT GAGGCGGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	42.19	4.00e-104	372.00
IUUC-Aml-001662	Ailuropoda melanoleuca	94.43	0.00e+00	1200.00
IUUC-Atr-002636	Amborella trichopoda	39.02	7.00e-110	391.00
IUUC-Apl-003369	Anas platyrhynchos	86.17	0.00e+00	972.00
IUUC-Aca-004490	Anolis carolinensis	79.81	0.00e+00	870.00
IUUC-Aly-006359	Arabidopsis lyrata	43.75	2.00e-101	362.00
IUUC-Ath-007667	Arabidopsis thaliana	44.38	5.00e-105	375.00
IUUC-Ago-007844	Ashbya gossypii	38.59	6.00e-84	305.00
IUUC-Acl-008270	Aspergillus clavatus	42.73	2.00e-101	363.00
IUUC-Afl-008674	Aspergillus flavus	44.71	1.00e-108	387.00
IUUC-Afu-008883	Aspergillus fumigatus	43.18	8.00e-104	371.00
IUUC-Ani-009500	Aspergillus nidulans	46.07	2.00e-114	405.00
IUUC-Ang-009535	Aspergillus niger	45.24	2.00e-108	386.00
IUUC-Aor-010223	Aspergillus oryzae	45.85	1.00e-110	393.00
IUUC-Ate-010282	Aspergillus terreus	43.93	7.00e-90	324.00
IUUC-Ame-011736	Astyanax mexicanus	75.47	0.00e+00	948.00
IUUC-Bgr-012166	Blumeria graminis	45.81	3.00e-97	349.00
IUUC-Bta-012589	Bos taurus	94.43	0.00e+00	1196.00
IUUC-Bci-013802	Botrytis cinerea	45.47	4.00e-99	355.00
IUUC-Bdi-014697	Brachypodium distachyon	44.00	3.00e-108	385.00
IUUC-Bol-016315	Brassica oleracea	45.02	3.00e-106	379.00
IUUC-Bra-018066	Brassica rapa	44.26	1.00e-104	373.00
IUUC-Cel-018708	Caenorhabditis elegans	47.46	6.00e-127	447.00
IUUC-Cja-019120	Callithrix jacchus	95.98	0.00e+00	1168.00
IUUC-Cfa-021061	Canis familiaris	94.43	0.00e+00	1196.00
IUUC-Cpo-021842	Cavia porcellus	94.27	0.00e+00	1153.00
IUUC-Csa-024104	Chlorocebus sabaeus	96.59	0.00e+00	1142.00
IUUC-Cho-024332	Choloepus hoffmanni	82.53	0.00e+00	820.00
IUUC-Cin-025363	Ciona intestinalis	60.45	0.00e+00	660.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	45.14	4.00e-97	348.00
IUUC-Cne-026888	Cryptococcus neoformans	53.05	1.00e-72	267.00
IUUC-Cme-027315	Cyanidioschyzon merolae	34.42	6.00e-60	225.00
IUUC-Dre-028420	Danio rerio	71.86	0.00e+00	868.00
IUUC-Dno-030041	Dasypus novemcinctus	93.96	0.00e+00	1157.00
IUUC-Dor-031039	Dipodomys ordii	76.46	2.00e-171	595.00
IUUC-Dse-031504	Dothistroma septosporum	42.76	3.00e-94	339.00
IUUC-Dme-031771	Drosophila melanogaster	48.28	1.00e-139	490.00
IUUC-Ete-033037	Echinops telfairi	88.37	0.00e+00	1029.00
IUUC-Eca-033774	Equus caballus	94.33	0.00e+00	1151.00
IUUC-Eeu-035074	Erinaceus europaeus	92.49	0.00e+00	914.00
IUUC-Fca-036508	Felis catus	94.50	0.00e+00	1153.00
IUUC-Fal-036813	Ficedula albicollis	83.95	0.00e+00	966.00
IUUC-Fox-038056	Fusarium oxysporum	44.53	3.00e-103	369.00
IUUC-Fso-038223	Fusarium solani	43.54	9.00e-101	360.00
IUUC-Gmo-038526	Gadus morhua	72.30	0.00e+00	857.00
IUUC-Ggr-039767	Gaeumannomyces graminis	43.95	2.00e-99	356.00
IUUC-Gga-040981	Gallus gallus	84.96	0.00e+00	999.00
IUUC-Gac-041437	Gasterosteus aculeatus	73.57	0.00e+00	890.00
IUUC-Gma-044072	Glycine max	37.09	1.00e-111	397.00
IUUC-Hsa-046068	Homo sapiens	96.44	0.00e+00	1135.00
IUUC-Hvu-047646	Hordeum vulgare	37.32	1.00e-104	373.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	94.27	0.00e+00	1154.00
IUUC-Lch-049565	Latimeria chalumnae	78.70	0.00e+00	988.00
IUUC-Lpe-050884	Leersia perrieri	42.74	6.00e-106	378.00
IUUC-Loc-052493	Lepisosteus oculatus	78.99	0.00e+00	982.00
IUUC-Lma-053117	Leptosphaeria maculans	44.20	8.00e-102	364.00
IUUC-Laf-054518	Loxodonta africana	91.02	0.00e+00	1133.00
IUUC-Mcc-055334	Macaca mulatta	95.98	0.00e+00	1132.00
IUUC-Mor-057137	Magnaporthe oryzae	44.03	4.00e-94	338.00
IUUC-Mpo-057449	Magnaporthe poae	44.89	3.00e-99	355.00
IUUC-Mtr-058045	Medicago truncatula	38.18	3.00e-116	412.00
IUUC-Mla-058864	Melampsora laricipopulina	45.72	2.00e-96	345.00
IUUC-Mga-059422	Meleagris gallopavo	80.13	0.00e+00	876.00
IUUC-Mvi-060536	Microbotryum violaceum	43.44	3.00e-85	309.00
IUUC-Mmr-061161	Microcebus murinus	93.01	0.00e+00	1150.00
IUUC-Mdo-061802	Monodelphis domestica	89.63	0.00e+00	1087.00
IUUC-Mmu-064357	Mus musculus	90.70	0.00e+00	1142.00
IUUC-Mac-065475	Musa acuminata	37.60	2.00e-108	386.00
IUUC-Mpu-066895	Mustela putorius furo	94.58	0.00e+00	1196.00
IUUC-Mlu-067862	Myotis lucifugus	93.81	0.00e+00	1199.00
IUUC-Nfi-068385	Neosartorya fischeri	45.61	4.00e-107	382.00
IUUC-Ncr-068885	Neurospora crassa	44.65	3.00e-103	369.00
IUUC-Nle-069524	Nomascus leucogenys	95.67	0.00e+00	1119.00
IUUC-Opr-071038	Ochotona princeps	93.96	0.00e+00	1188.00
IUUC-Ont-071719	Oreochromis niloticus	73.43	0.00e+00	936.00
IUUC-Oan-072877	Ornithorhynchus anatinus	87.00	0.00e+00	935.00
IUUC-Ocu-074080	Oryctolagus cuniculus	93.81	0.00e+00	1143.00
IUUC-Oba-075936	Oryza barthii	42.32	2.00e-106	379.00
IUUC-Obr-076841	Oryza brachyantha	37.95	1.00e-107	383.00
IUUC-Ogl-077686	Oryza glaberrima	42.32	7.00e-108	384.00
IUUC-Ogu-078597	Oryza glumaepatula	41.02	2.00e-103	369.00
IUUC-Oin-079791	Oryza indica	42.32	2.00e-106	379.00
IUUC-Olo-081009	Oryza longistaminata	42.32	2.00e-106	380.00
IUUC-Ome-081327	Oryza meridionalis	38.73	1.00e-100	360.00
IUUC-Oni-082334	Oryza nivara	41.27	5.00e-104	371.00
IUUC-Opu-083447	Oryza punctata	42.32	2.00e-106	380.00
IUUC-Oru-084977	Oryza rufipogon	42.32	2.00e-106	379.00
IUUC-Osa-086160	Oryza sativa	43.98	3.00e-96	345.00
IUUC-Ola-087415	Oryzias latipes	72.67	0.00e+00	891.00
IUUC-Olu-087850	Ostreococcus lucimarinus	39.52	2.00e-97	349.00
IUUC-Oga-088434	Otolemur garnettii	94.43	0.00e+00	1155.00
IUUC-Oar-089872	Ovis aries	94.00	0.00e+00	1151.00
IUUC-Ptr-091212	Pan troglodytes	96.44	0.00e+00	1135.00
IUUC-Pan-092708	Papio anubis	99.61	4.00e-133	468.00
IUUC-Psi-093703	Pelodiscus sinensis	85.83	0.00e+00	998.00
IUUC-Pno-094953	Phaeosphaeria nodorum	46.06	5.00e-106	378.00
IUUC-Ppa-095963	Physcomitrella patens	46.22	6.00e-108	384.00
IUUC-Pfo-097515	Poecilia formosa	72.13	0.00e+00	890.00
IUUC-Pab-097951	Pongo abelii	95.64	0.00e+00	979.00
IUUC-Pop-099703	Populus trichocarpa	38.91	3.00e-91	329.00
IUUC-Pca-100426	Procavia capensis	91.49	0.00e+00	1153.00
IUUC-Ppe-101152	Prunus persica	37.60	5.00e-109	388.00
IUUC-Pva-102792	Pteropus vampyrus	89.41	0.00e+00	1098.00
IUUC-Pgr-103592	Puccinia graminis	39.09	6.00e-101	361.00
IUUC-Ptt-103805	Puccinia triticina	41.92	5.00e-87	315.00
IUUC-Pte-104215	Pyrenophora teres	44.56	1.00e-112	400.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	46.24	4.00e-111	395.00
IUUC-Rno-106117	Rattus norvegicus	91.16	0.00e+00	1146.00
IUUC-Sce-106177	Saccharomyces cerevisiae	32.82	4.00e-76	279.00
IUUC-Sha-107006	Sarcophilus harrisii	89.81	0.00e+00	1091.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	43.96	2.00e-94	340.00
IUUC-Spo-108020	Schizosaccharomyces pombe	44.38	5.00e-96	345.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	44.75	2.00e-101	362.00
IUUC-Smo-109264	Selaginella moellendorffii	40.60	5.00e-105	374.00
IUUC-Sit-110581	Setaria italica	42.30	3.00e-106	379.00
IUUC-Sly-111870	Solanum lycopersicum	38.05	1.00e-107	384.00
IUUC-Stu-112283	Solanum tuberosum	38.34	2.00e-105	376.00
IUUC-Sar-113432	Sorex araneus	69.35	0.00e+00	741.00
IUUC-Sbi-114075	Sorghum bicolor	40.73	6.00e-105	374.00
IUUC-Sre-114926	Sporisorium reilianum	46.36	4.00e-102	365.00
IUUC-Ssc-116281	Sus scrofa	98.62	3.00e-118	417.00
IUUC-Tgu-117247	Taeniopygia guttata	82.70	0.00e+00	964.00
IUUC-Tru-118075	Takifugu rubripes	68.66	0.00e+00	849.00
IUUC-Tsy-119398	Tarsius syrichta	81.49	0.00e+00	931.00
IUUC-Tni-120771	Tetraodon nigroviridis	63.72	0.00e+00	758.00
IUUC-Tca-121651	Theobroma cacao	38.24	2.00e-105	376.00
IUUC-Tre-122224	Trichoderma reesei	45.19	5.00e-92	332.00
IUUC-Tvi-122634	Trichoderma virens	43.36	2.00e-92	333.00
IUUC-Tae-125665	Triticum aestivum	42.71	7.00e-103	367.00
IUUC-Tur-126417	Triticum urartu	41.20	1.00e-102	367.00
IUUC-Tme-127016	Tuber melanosporum	44.59	2.00e-97	349.00
IUUC-Tbe-127678	Tupaia belangeri	76.61	6.00e-161	560.00
IUUC-Ttr-128598	Tursiops truncatus	90.40	0.00e+00	1132.00
IUUC-Uma-129612	Ustilago maydis	43.85	4.00e-97	348.00
IUUC-Vda-129811	Verticillium dahliae	45.41	3.00e-100	358.00
IUUC-Vpa-130732	Vicugna pacos	80.47	0.00e+00	977.00
IUUC-Vvi-130832	Vitis vinifera	39.17	3.00e-104	372.00
IUUC-Xtr-132823	Xenopus tropicalis	73.68	0.00e+00	889.00
IUUC-Xma-133552	Xiphophorus maculatus	71.97	0.00e+00	889.00
IUUC-Yli-134666	Yarrowia lipolytica	37.66	3.00e-76	279.00
IUUC-Zma-135547	Zea mays	41.65	7.00e-105	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence