iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048012

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01100811

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000005336.2	ENSSTOT00000005327.2	ENSSTOP00000004775.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	4.40e-48	163.2	41	230

Active Site

Position(s)	Description	Evidence
48	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
51	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
224		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+ktkgDGnC++rA++++                                                          ll+vf+d+s sd
   Q: 41   AIRKTKGDGNCFYRALGYAylesllgksreilkfkervlqtpsdllaagfeehkfrnffnafysvvelverdgsvssLLKVFNDQSSSD 129
           79*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
           ++v++Lr+lts+++++++dff++fi+e++d+k+fc+++vep+a  +++i+i+aL+q+L+++++v++vd++++    +l++++fpe++  
   Q: 130  HIVQFLRLLTSAFIKNRADFFRHFIDEEMDIKDFCTHEVEPMAMeCDHIQITALSQALNIALQVEYVDEMDT----ALNHHVFPEAA-V 213
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+++HY++L+a
   Q: 214  PSVYLLYKTSHYNILYA 230
           ***************97 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSETSFNLIS EKCDILSILR DHPENRIYQR KIQELSKRFT AIRKTKGDGN CFYRALGYAY 60
LESLLGKSRE ILKFKERVLQ TPSDLLAAGF EEHKFRNFFN AFYSVVELVE RDGSVSSLLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGACACAGT GGCGGTCTAA CCTTTGCTTT GCGGAGCGGT CGGGTGTATT CTCCGCACGC 60
CCCCCACGCC CTCGAGGCCC CCGCCGCCCG ACCCAACGGT GGAGCCGACC AACGCCTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	96.55	2.00e-133	467.00
IUUC-Bta-012766	Bos taurus	95.73	7.00e-133	465.00
IUUC-Cja-019480	Callithrix jacchus	94.44	4.00e-132	462.00
IUUC-Cfa-021106	Canis familiaris	96.98	6.00e-134	469.00
IUUC-Cpo-022187	Cavia porcellus	94.85	4.00e-132	463.00
IUUC-Csa-023493	Chlorocebus sabaeus	95.28	2.00e-132	463.00
IUUC-Cho-024411	Choloepus hoffmanni	77.07	8.00e-86	308.00
IUUC-Dno-029346	Dasypus novemcinctus	97.00	6.00e-134	469.00
IUUC-Dor-031012	Dipodomys ordii	97.00	4.00e-135	473.00
IUUC-Ete-032266	Echinops telfairi	88.36	1.00e-120	424.00
IUUC-Eca-033356	Equus caballus	96.55	4.00e-133	466.00
IUUC-Eeu-034775	Erinaceus europaeus	96.12	5.00e-133	466.00
IUUC-Fca-035363	Felis catus	94.83	2.00e-131	460.00
IUUC-Ggo-045023	Gorilla gorilla	94.87	1.00e-132	464.00
IUUC-Hsa-046984	Homo sapiens	95.30	4.00e-133	466.00
IUUC-Lch-050514	Latimeria chalumnae	61.78	7.00e-84	303.00
IUUC-Loc-052003	Lepisosteus oculatus	51.10	1.00e-65	242.00
IUUC-Laf-054382	Loxodonta africana	96.12	3.00e-133	466.00
IUUC-Mcc-055516	Macaca mulatta	95.28	2.00e-132	464.00
IUUC-Meu-056038	Macropus eugenii	88.89	7.00e-100	355.00
IUUC-Mmr-060918	Microcebus murinus	97.01	5.00e-135	473.00
IUUC-Mdo-062638	Monodelphis domestica	90.13	2.00e-125	441.00
IUUC-Mmu-063973	Mus musculus	95.71	3.00e-133	467.00
IUUC-Mpu-066013	Mustela putorius furo	96.55	1.00e-133	468.00
IUUC-Mlu-067509	Myotis lucifugus	93.10	2.00e-128	450.00
IUUC-Nle-069673	Nomascus leucogenys	95.30	4.00e-133	466.00
IUUC-Opr-070761	Ochotona princeps	87.35	2.00e-81	294.00
IUUC-Oan-072922	Ornithorhynchus anatinus	82.53	2.00e-112	397.00
IUUC-Ocu-074643	Oryctolagus cuniculus	94.87	7.00e-133	465.00
IUUC-Oni-082026	Oryza nivara	27.43	2.00e-15	76.60
IUUC-Oru-084761	Oryza rufipogon	27.43	2.00e-15	76.60
IUUC-Ola-086603	Oryzias latipes	45.83	4.00e-52	197.00
IUUC-Oga-088936	Otolemur garnettii	95.71	7.00e-133	465.00
IUUC-Oar-089460	Ovis aries	96.14	2.00e-132	464.00
IUUC-Ptr-090805	Pan troglodytes	94.87	9.00e-133	465.00
IUUC-Pan-091969	Papio anubis	95.30	4.00e-133	466.00
IUUC-Pab-098476	Pongo abelii	94.85	8.00e-132	462.00
IUUC-Pca-100252	Procavia capensis	92.08	8.00e-54	202.00
IUUC-Pva-102204	Pteropus vampyrus	95.73	4.00e-134	469.00
IUUC-Pgr-103552	Puccinia graminis	75.00	2.30e-02	31.20
IUUC-Rno-105062	Rattus norvegicus	95.30	2.00e-133	467.00
IUUC-Sha-106968	Sarcophilus harrisii	89.96	4.00e-123	433.00
IUUC-Sar-113295	Sorex araneus	96.98	2.00e-131	460.00
IUUC-Ssc-115288	Sus scrofa	96.14	1.00e-133	468.00
IUUC-Tni-120440	Tetraodon nigroviridis	40.26	1.00e-43	168.00
IUUC-Tbe-127717	Tupaia belangeri	94.59	2.00e-78	283.00
IUUC-Ttr-128221	Tursiops truncatus	77.25	5.00e-101	359.00
IUUC-Uma-129443	Ustilago maydis	34.13	6.00e-25	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence