iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049241

Ensembl Protein ID

CAY72043

UniProt Accession

C4R8W8; C4R8W8_KOMPG

Genbank Protein ID

CAY72043.1

Protein Name

Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA

Genbank Nucleotide ID

FN392322

Gene Name

PAS_chr4_0778

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr4_0778	CAY72043	CAY72043

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-22	77.2	55	88
UBD/Beta-Prp	7.20e-47	158.0	10	246

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtg 33
           Ht +v c+++   +  +l+s s D++ik+W ++++
   Q: 55   HTKEVLCVKWvplT-SFLLSTSEDCSIKLWKVDDN 88
           999********842.79**************9875 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdls...tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdle...tgqcleetlsghdgvvncvv 144
           g++ e ++ ++s++   +v  +   ti +w++        v tlk h+++vl++++ p +++l+s+s+d  i++w+++   t+++l  t + h+++v++++
   Q: 10   GCNRELYTSDYSERF-KRVAFGAGITISIWNPLandYKGVVTTLKSHTKEVLCVKWVPLTSFLLSTSEDCSIKLWKVDdngTDYELVGTTNHHKHSVTSLA 109
           666777788888888.688888899*****776232333678899******************************8863226677777************* PP
   S: 145  vhpdgnllvsGslDrtvrlWdl...ktgkllrtltgghtdsvysls.....fdsngkelvsgsldgtvklwdlq.....tgec......vrtlnghtdnvk 226
           + + ++l+ sG + + + +W +      +ll+++t   +d  ysls     +++  +  + g++++ + ++++      +            l gh+d+vk
   Q: 110  LAG-SSLFLSGDASGLLCFWHIsgkGDLELLHEFTV--KDGFYSLSlalqqLSDGDFLALIGGTNTNIYVYSFNydkspA--KiakfaqSAVLAGHEDWVK 205
           ***.9*****************76556678999975..9*******66665555559999**************766540..1455555778999****** PP
   S: 227  svrfs..pnderlvsgssDgsiriW........dlrsgdll 257
           s+ +   + d +++sg++D+ ir+W        d+   d +
   Q: 206  SIVVKmhEGDFFIASGAQDRYIRLWklslnekiDVSDEDST 246
           988876699****************6666555544444333 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MASVESIFIG CNRELYTSDY SERFKRVAFG AGITISIWNP LANDYKGVVT TLKSHTKEVL 60
CVKWVPLTSF LLSTSEDCSI KLWKVDDNGT DYELVGTTNH HKHSVTSLAL AGSSLFLSGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG TAGAAAGTAT CTTTATTGGT TGCAATCGAG AACTGTATAC CAGTGATTAC 60
AGTGAGAGGT TCAAACGGGT CGCTTTCGGG GCAGGAATCA CCATTTCCAT CTGGAACCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0033588--C:Elongator holoenzyme complex
GO:0005634--C:nucleus
GO:0032447--P:protein urmylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0002098--P:tRNA wobble uridine modification

KEGG

ppa:PAS_chr4_0778

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000056	Aegilops tauschii	30.43	6.00e-89	320.00
IUUC-Aml-002049	Ailuropoda melanoleuca	31.24	2.00e-89	321.00
IUUC-Atr-002456	Amborella trichopoda	30.99	6.00e-95	339.00
IUUC-Apl-004053	Anas platyrhynchos	32.93	8.00e-104	369.00
IUUC-Aca-004535	Anolis carolinensis	31.73	3.00e-97	347.00
IUUC-Aly-005746	Arabidopsis lyrata	31.57	1.00e-88	319.00
IUUC-Ath-006664	Arabidopsis thaliana	31.57	1.00e-87	315.00
IUUC-Ago-007971	Ashbya gossypii	48.68	0.00e+00	694.00
IUUC-Acl-008173	Aspergillus clavatus	36.98	3.00e-140	490.00
IUUC-Afl-008665	Aspergillus flavus	33.47	5.00e-60	223.00
IUUC-Afu-008976	Aspergillus fumigatus	37.88	4.00e-143	499.00
IUUC-Ani-009284	Aspergillus nidulans	37.06	3.00e-137	480.00
IUUC-Ang-009809	Aspergillus niger	37.48	9.00e-142	495.00
IUUC-Aor-009959	Aspergillus oryzae	37.58	1.00e-142	498.00
IUUC-Ate-010442	Aspergillus terreus	37.70	4.00e-142	496.00
IUUC-Ame-011409	Astyanax mexicanus	30.39	3.00e-87	314.00
IUUC-Bgr-012137	Blumeria graminis	34.43	6.00e-124	436.00
IUUC-Bta-012892	Bos taurus	31.66	2.00e-104	370.00
IUUC-Bci-013944	Botrytis cinerea	34.90	5.00e-124	436.00
IUUC-Bdi-014512	Brachypodium distachyon	30.53	4.00e-96	343.00
IUUC-Bol-015741	Brassica oleracea	31.46	3.00e-94	337.00
IUUC-Bra-017367	Brassica rapa	31.37	2.00e-95	341.00
IUUC-Cel-018712	Caenorhabditis elegans	31.09	2.00e-76	278.00
IUUC-Cja-018865	Callithrix jacchus	31.14	5.00e-96	343.00
IUUC-Cfa-021006	Canis familiaris	30.98	2.00e-104	371.00
IUUC-Cpo-021370	Cavia porcellus	31.84	2.00e-103	367.00
IUUC-Csa-023845	Chlorocebus sabaeus	32.22	3.00e-106	377.00
IUUC-Cho-024640	Choloepus hoffmanni	27.99	2.00e-54	205.00
IUUC-Cin-025772	Ciona intestinalis	33.33	1.00e-101	361.00
IUUC-Csv-025891	Ciona savignyi	32.18	3.00e-99	353.00
IUUC-Cgl-026443	Colletotrichum gloeosporioides	35.95	2.00e-131	460.00
IUUC-Cne-027081	Cryptococcus neoformans	30.54	4.00e-85	307.00
IUUC-Cme-027225	Cyanidioschyzon merolae	25.31	9.00e-44	169.00
IUUC-Dre-028250	Danio rerio	29.97	1.00e-88	318.00
IUUC-Dno-028847	Dasypus novemcinctus	30.97	4.00e-104	370.00
IUUC-Dor-030351	Dipodomys ordii	31.35	2.00e-100	358.00
IUUC-Dse-031317	Dothistroma septosporum	34.94	9.00e-125	439.00
IUUC-Dme-032019	Drosophila melanogaster	32.76	4.00e-102	363.00
IUUC-Ete-033194	Echinops telfairi	30.82	1.00e-48	186.00
IUUC-Eca-033779	Equus caballus	31.27	1.00e-101	362.00
IUUC-Eeu-034790	Erinaceus europaeus	31.62	1.00e-64	238.00
IUUC-Fca-036090	Felis catus	31.65	2.00e-103	368.00
IUUC-Fal-037663	Ficedula albicollis	33.38	1.00e-95	342.00
IUUC-Fox-037828	Fusarium oxysporum	34.34	2.00e-131	461.00
IUUC-Fso-038462	Fusarium solani	37.63	4.00e-135	473.00
IUUC-Gmo-039450	Gadus morhua	31.07	6.00e-90	323.00
IUUC-Ggr-040023	Gaeumannomyces graminis	34.53	6.00e-118	416.00
IUUC-Gga-040480	Gallus gallus	32.21	1.00e-99	355.00
IUUC-Gac-041544	Gasterosteus aculeatus	29.90	2.00e-92	331.00
IUUC-Gma-044048	Glycine max	30.72	1.00e-100	358.00
IUUC-Ggo-045381	Gorilla gorilla	30.17	8.00e-95	339.00
IUUC-Hsa-046096	Homo sapiens	33.08	3.00e-96	344.00
IUUC-Hvu-047494	Hordeum vulgare	30.95	6.00e-94	336.00
IUUC-Itr-048823	Ictidomys tridecemlineatus	32.78	5.00e-82	296.00
IUUC-Lch-050512	Latimeria chalumnae	32.84	2.00e-87	314.00
IUUC-Lpe-051448	Leersia perrieri	30.03	2.00e-92	331.00
IUUC-Loc-051882	Lepisosteus oculatus	31.27	7.00e-98	349.00
IUUC-Lma-053023	Leptosphaeria maculans	35.95	6.00e-135	472.00
IUUC-Laf-054519	Loxodonta africana	31.37	5.00e-103	366.00
IUUC-Mcc-055580	Macaca mulatta	30.80	9.00e-99	352.00
IUUC-Meu-056606	Macropus eugenii	41.03	8.00e-30	123.00
IUUC-Mor-057109	Magnaporthe oryzae	35.57	8.00e-138	482.00
IUUC-Mpo-057297	Magnaporthe poae	33.08	6.00e-123	432.00
IUUC-Mtr-058348	Medicago truncatula	30.12	2.00e-99	354.00
IUUC-Mla-059159	Melampsora laricipopulina	28.65	3.00e-84	304.00
IUUC-Mga-059778	Meleagris gallopavo	34.26	2.00e-62	231.00
IUUC-Mvi-060447	Microbotryum violaceum	30.25	5.00e-93	333.00
IUUC-Mmr-061139	Microcebus murinus	32.04	7.00e-97	346.00
IUUC-Mdo-061866	Monodelphis domestica	32.17	1.00e-103	369.00
IUUC-Mmu-063390	Mus musculus	31.24	2.00e-100	357.00
IUUC-Mac-064693	Musa acuminata	31.16	1.00e-93	335.00
IUUC-Mpu-066547	Mustela putorius furo	31.61	2.00e-103	367.00
IUUC-Mlu-067156	Myotis lucifugus	30.33	6.00e-100	356.00
IUUC-Nfi-068616	Neosartorya fischeri	37.20	3.00e-146	510.00
IUUC-Ncr-068915	Neurospora crassa	34.36	1.00e-122	431.00
IUUC-Nle-069958	Nomascus leucogenys	31.99	8.00e-105	372.00
IUUC-Opr-071093	Ochotona princeps	28.14	8.00e-38	149.00
IUUC-Ont-072178	Oreochromis niloticus	30.82	7.00e-96	342.00
IUUC-Oan-073667	Ornithorhynchus anatinus	32.45	1.00e-98	352.00
IUUC-Ocu-074662	Oryctolagus cuniculus	32.86	1.00e-103	368.00
IUUC-Oba-075577	Oryza barthii	30.32	7.00e-97	346.00
IUUC-Obr-076566	Oryza brachyantha	29.89	2.00e-93	334.00
IUUC-Ogl-077054	Oryza glaberrima	30.59	6.00e-98	349.00
IUUC-Ogu-078846	Oryza glumaepatula	30.19	6.00e-96	343.00
IUUC-Oin-079084	Oryza indica	30.05	1.00e-96	345.00
IUUC-Olo-080933	Oryza longistaminata	28.19	6.00e-78	283.00
IUUC-Ome-081500	Oryza meridionalis	27.88	1.00e-79	289.00
IUUC-Oni-082352	Oryza nivara	30.19	3.00e-96	344.00
IUUC-Opu-084116	Oryza punctata	30.05	5.00e-94	336.00
IUUC-Oru-085249	Oryza rufipogon	30.05	1.00e-96	345.00
IUUC-Osa-086270	Oryza sativa	30.05	1.00e-96	345.00
IUUC-Ola-086625	Oryzias latipes	29.17	6.00e-81	293.00
IUUC-Olu-087638	Ostreococcus lucimarinus	29.34	8.00e-63	232.00
IUUC-Oga-088634	Otolemur garnettii	32.78	8.00e-87	313.00
IUUC-Oar-089475	Ovis aries	31.07	4.00e-103	367.00
IUUC-Ptr-091131	Pan troglodytes	32.01	7.00e-106	375.00
IUUC-Pan-092869	Papio anubis	31.45	1.00e-104	371.00
IUUC-Psi-093146	Pelodiscus sinensis	34.80	4.00e-97	346.00
IUUC-Pma-094479	Petromyzon marinus	34.94	3.00e-92	331.00
IUUC-Pno-095061	Phaeosphaeria nodorum	34.67	1.00e-98	352.00
IUUC-Ppa-095618	Physcomitrella patens	31.25	1.00e-88	320.00
IUUC-Pfo-096816	Poecilia formosa	31.66	1.00e-93	335.00
IUUC-Pab-097548	Pongo abelii	32.09	2.00e-106	377.00
IUUC-Pop-099643	Populus trichocarpa	29.42	4.00e-94	337.00
IUUC-Pca-100983	Procavia capensis	26.62	2.00e-40	159.00
IUUC-Ppe-101301	Prunus persica	32.15	2.00e-95	341.00
IUUC-Pva-102460	Pteropus vampyrus	30.10	3.00e-100	357.00
IUUC-Pgr-103507	Puccinia graminis	30.48	3.00e-85	307.00
IUUC-Ptt-103892	Puccinia triticina	29.72	3.00e-76	277.00
IUUC-Pte-104283	Pyrenophora teres	37.74	2.00e-136	477.00
IUUC-Pyt-104465	Pyrenophora triticirepentis	36.61	1.00e-132	464.00
IUUC-Rno-105842	Rattus norvegicus	31.59	2.00e-101	361.00
IUUC-Sce-106459	Saccharomyces cerevisiae	49.49	0.00e+00	712.00
IUUC-Sha-106586	Sarcophilus harrisii	28.01	7.00e-65	240.00
IUUC-Sja-107868	Schizosaccharomyces japonicus	35.21	3.00e-111	394.00
IUUC-Spo-108302	Schizosaccharomyces pombe	35.05	1.00e-119	421.00
IUUC-Smo-108919	Selaginella moellendorffii	30.08	1.00e-94	338.00
IUUC-Sit-109915	Setaria italica	29.92	2.00e-94	338.00
IUUC-Sly-111714	Solanum lycopersicum	30.39	2.00e-90	324.00
IUUC-Stu-112631	Solanum tuberosum	30.09	2.00e-91	328.00
IUUC-Sar-113200	Sorex araneus	27.34	4.00e-55	207.00
IUUC-Sbi-114582	Sorghum bicolor	30.29	5.00e-96	343.00
IUUC-Sre-115001	Sporisorium reilianum	35.69	4.00e-39	155.00
IUUC-Ssc-115519	Sus scrofa	31.44	3.00e-102	364.00
IUUC-Tgu-116987	Taeniopygia guttata	31.04	1.00e-95	342.00
IUUC-Tru-118476	Takifugu rubripes	31.80	2.00e-91	328.00
IUUC-Tsy-119230	Tarsius syrichta	43.24	1.00e-27	116.00
IUUC-Tni-120448	Tetraodon nigroviridis	25.28	7.00e-29	120.00
IUUC-Tca-121650	Theobroma cacao	31.66	2.00e-95	341.00
IUUC-Tre-122086	Trichoderma reesei	36.02	1.00e-126	444.00
IUUC-Tvi-122397	Trichoderma virens	35.89	8.00e-123	432.00
IUUC-Tae-125257	Triticum aestivum	30.20	2.00e-92	331.00
IUUC-Tur-126578	Triticum urartu	30.17	6.00e-93	333.00
IUUC-Tme-126927	Tuber melanosporum	38.94	4.00e-138	483.00
IUUC-Tbe-127922	Tupaia belangeri	37.79	4.00e-41	160.00
IUUC-Ttr-128918	Tursiops truncatus	31.62	5.00e-103	366.00
IUUC-Uma-129474	Ustilago maydis	31.63	2.00e-38	152.00
IUUC-Vda-129944	Verticillium dahliae	35.10	8.00e-128	449.00
IUUC-Vpa-130693	Vicugna pacos	32.24	1.00e-101	362.00
IUUC-Vvi-130949	Vitis vinifera	30.64	1.00e-94	338.00
IUUC-Xtr-132639	Xenopus tropicalis	34.30	5.00e-94	337.00
IUUC-Xma-134223	Xiphophorus maculatus	35.86	4.00e-66	243.00
IUUC-Yli-134601	Yarrowia lipolytica	39.26	5.00e-150	522.00
IUUC-Zma-135952	Zea mays	30.80	5.00e-97	347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence